Metabolomics Laboratory Featured Publications
Our staff members and collaborators frequently publish their research in leading peer-reviewed publications. Here is a selection of their recent accomplishments.
Selected Publications
Genome-wide screening identifies Trim33 as an essential regulator of dendritic cell differentiation
Science immunology. 2024 Apr 12; 9:eadi1023
Chemosensory detection of polyamine metabolites guides C. elegans to nutritive microbes
Science advances. 2024 Mar 22; 10:eadj4387
Disruption of lysosomal proteolysis in astrocytes facilitates midbrain organoid proteostasis failure in an early-onset Parkinson's disease model
Nature communications. 2024 Jan 10; 15:447
Targeting pancreatic cancer metabolic dependencies through glutamine antagonism
Nature cancer. 2024 Jan ; 5:85-99
Intestinal microbiome and metabolome signatures in patients with chronic granulomatous disease
Journal of allergy & clinical immunology. 2023 Dec ; 152:1619-1633.e11
The expression profile and tumorigenic mechanisms of CD97 (ADGRE5) in glioblastoma render it a targetable vulnerability
Cell reports. 2023 Nov 28; 42:113374
Modulation of GluA2-γ5 synaptic complex desensitization, polyamine block and antiepileptic perampanel inhibition by auxiliary subunit cornichon-2
Nature structural & molecular biology. 2023 Oct ; 30:1481-1494
In vivo metabolomics identifies CD38 as an emergent vulnerability in LKB1 -mutant lung cancer
bioRxiv.org : the preprint server for biology. 2023 Apr 20;