Research

More Power to the Mitochondria: Cells’ Energy Plant Also Plays Key Role in Stem Cell Development

Researchers at NYU Langone Medical Center have discovered that mitochondria, the major energy source for most cells, also play an important role in stem cell development. Specifically, the NYU Langone team, led by senior study investigator and cell biologist, Ruth Lehmann, PhD, found that blocking the action of the mitochondrial ATP synthase enzyme stalled egg cell development from stem cells in experiments in fruit flies, one of the main organisms used to study cell biology. The results were published in the journal Nature Cell Biology. Read more…


Extending Treatment Up To Eight Weeks with Infusion Medication Shown Safe and Effective in Patients with Multiple Sclerosis

Extending the dose of an infusion medication for multiple sclerosis (MS) from four weeks up to eight has been shown to be well tolerated and effective—and resulted in no cases of the potentially fatal side effect progressive multifocal leukoencephalopathy (PML), according to a new study led by NYULMC researchers. The study of close to 2,000 patients showed that the drug, natalizumab, had similar efficacy in treating disease activity, says lead investigator Lana Zhovtis Ryerson, MD. The findings were presented at the American Academy of Neurology annual meeting, held April 18-25 in Washington, D.C. Read more…