Research

Factor Preserves DNA Integrity in Bacteria Despite Assault from Antibiotics

A key biochemical enables bacteria to repair otherwise fatal damage to their DNA, including damage caused by antibiotics, according to a study led by researchers at NYU Langone Medical Center, which was published in the journal Science. “Most antibiotics have their effect, directly or indirectly, by causing damage to bacterial DNA, so finding ways to cripple DNA repair would represent a significant advance in the treatment of resistant infections,” says senior study author Evgeny Nudler, PhD, the Julie Wilson Anderson Professor of Biochemistry in the Department of Biochemistry and Molecular Pharmacology. Read more…


Testosterone Therapy Does Not Raise Risk of Aggressive Prostate Cancer, Study Suggests

Men with low levels of the male sex hormone testosterone need not fear that testosterone replacement therapy will increase their risk of prostate cancer according to researchers at NYU Langone’s Laura and Isaac Perlmutter Cancer Center. “Based on our findings, physicians should still watch for prostate cancer risk factors in men taking testosterone therapy, but should not hesitate to prescribe it to appropriate patients for fear of increasing prostate cancer risk,” says lead study investigator Stacy Loeb, MD, MSc. Read more...