Da-Neng Wang, Ph.D.

Assembly and mechanism of a group II ECF transporter
Karpowich, Nathan K; Wang, Da-Neng
2013 Feb;110(7):2534-2539, Proceedings of the National Academy of Sciences of the United States of America
— id: 220862, year: 2013, vol: 110, page: 2534, stat: Journal Article,

Benjamin Franklin, Philadelphia's Favorite Son, was a Membrane Biophysicist
Wang, Da-Neng; Stieglitz, Heather; Marden, Jennifer; Tamm, Lukas K
2013 Jan;104(2):287-291, Biophysical journal
— id: 231242, year: 2013, vol: 104, page: 287, stat: Journal Article,

Identification and characterization of a bacterial hydrosulphide ion channel
Czyzewski, Bryan K; Wang, Da-Neng
2012 Mar;483(7390):494-497, Nature
— id: 162034, year: 2012, vol: 483, page: 494, stat: Journal Article,

Structure and mechanism of a bacterial sodium-dependent dicarboxylate transporter
Mancusso, Romina; Gregorio, G Glenn; Liu, Qun; Wang, Da-Neng
2012 Nov;491(7425):622-626, Nature
— id: 184922, year: 2012, vol: 491, page: 622, stat: Journal Article,

GEP constitutes a negative feedback loop with MyoD and acts as a novel mediator in controlling skeletal muscle differentiation
Wang D; Bai X; Tian Q; Lai Y; Lin EA; Shi Y; Mu X; Feng JQ; Carlson CS; Liu CJ
2012 Dec 17;:1855-1873 #, Cellular & molecular life sciences: CMLS
— id: 148767, year: 2012, vol: , page: 1855, stat: Journal Article,

Simple screening method for improving membrane protein thermostability
Mancusso, Romina; Karpowich, Nathan K; Czyzewski, Bryan K; Wang, Da-Neng
2011 Dec;55(4):324-329, Methods
— id: 150557, year: 2011, vol: 55, page: 324, stat: Journal Article,

Biophysics: Transporter in the spotlight
Karpowich, Nathan K; Wang, Da-Neng
2010 May 13;465(7295):171-172, Nature
— id: 132714, year: 2010, vol: 465, page: 171, stat: Journal Article,

The New York Consortium on Membrane Protein Structure (NYCOMPS): a high-throughput platform for structural genomics of integral membrane proteins
Love, James; Mancia, Filippo; Shapiro, Lawrence; Punta, Marco; Rost, Burkhard; Girvin, Mark; Wang, Da-Neng; Zhou, Ming; Hunt, John F; Szyperski, Thomas; Gouaux, Eric; MacKinnon, Roderick; McDermott, Ann; Honig, Barry; Inouye, Masayori; Montelione, Gaetano; Hendrickson, Wayne A
2010 Sep;11(3):191-199, Journal of structural & functional genomics
— id: 132716, year: 2010, vol: 11, page: 191, stat: Journal Article,

Substrate and drug binding sites in LeuT
Nyola, Ajeeta; Karpowich, Nathan K; Zhen, Juan; Marden, Jennifer; Reith, Maarten E; Wang, Da-Neng
2010 Aug;20(4):415-422, Current opinion in structural biology
— id: 112042, year: 2010, vol: 20, page: 415, stat: Journal Article,

Structure and mechanism of a pentameric formate channel
Waight, Andrew B; Love, James; Wang, Da-Neng
2010 Jan;17(1):31-37, Nature structural & molecular biology
— id: 106095, year: 2010, vol: 17, page: 31, stat: Journal Article,

Structural basis of substrate selectivity in the glycerol-3-phosphate: phosphate antiporter GlpT
Law, Christopher J; Enkavi, Giray; Wang, Da-Neng; Tajkhorshid, Emad
2009 Sep 2;97(5):1346-1353, Biophysical journal
— id: 132717, year: 2009, vol: 97, page: 1346, stat: Journal Article,

STRUCTURE OF THE LEUCINE TRANSPORTER LeuT IN COMPLEX WITH DESIPRAMINE SUGGESTS HOW ANTIDEPRESSANTS INHIBIT NEUROTRANSMITTER REUPTAKE
Wang, DN
2009 FEB ;59(2):116-116, Journal of physiological sciences : JPS
— id: 106962, year: 2009, vol: 59, page: 116, stat: Journal Article,

Antidepressant specificity of serotonin transporter suggested by three LeuT-SSRI structures
Zhou, Zheng; Zhen, Juan; Karpowich, Nathan K; Law, Christopher J; Reith, Maarten E A; Wang, Da-Neng
2009 Jun;16(6):652-657, Nature structural & molecular biology
— id: 103150, year: 2009, vol: 16, page: 652, stat: Journal Article,

Three-dimensional Architecture of Hair-bundle Linkages Revealed by Electron-microscopic Tomography
Auer, Manfred; Koster, Abrahram J; Ziese, Ulrike; Bajaj, Chandrajit; Volkmann, Niels; Wang, Da Neng; Hudspeth, A J
2008 Jun;9(2):215-224, Journal of the Association for Research in Otolaryngology : JARO
— id: 78730, year: 2008, vol: 9, page: 215, stat: Journal Article,

Structural biology. Symmetric transporters for asymmetric transport
Karpowich, Nathan K; Wang, Da-Neng
2008 Aug 8;321(5890):781-782, Science
— id: 81068, year: 2008, vol: 321, page: 781, stat: Journal Article,

Salt-bridge dynamics control substrate-induced conformational change in the membrane transporter GlpT
Law, Christopher J; Almqvist, Jonas; Bernstein, Adam; Goetz, Regina M; Huang, Yafei; Soudant, Celine; Laaksonen, Aatto; Hovmoller, Sven; Wang, Da-Neng
2008 May 9;378(4):828-839, Journal of molecular biology
— id: 78697, year: 2008, vol: 378, page: 828, stat: Journal Article,

Ins and outs of major facilitator superfamily antiporters
Law, Christopher J; Maloney, Peter C; Wang, Da-Neng
2008 ;62:289-305, Annual review of microbiology
— id: 93312, year: 2008, vol: 62, page: 289, stat: Journal Article,

Docking and homology modeling explain inhibition of the human vesicular glutamate transporters
Almqvist, Jonas; Huang, Yafei; Laaksonen, Aatto; Wang, Da-Neng; Hovmoller, Sven
2007 Sep;16(9):1819-1829, Protein science
— id: 132718, year: 2007, vol: 16, page: 1819, stat: Journal Article,

Kinetic Evidence Is Consistent with the Rocker-Switch Mechanism of Membrane Transport by GlpT
Law, Christopher J; Yang, Qiang; Soudant, Celine; Maloney, Peter C; Wang, Da-Neng
2007 Oct 30;46(43):12190-12197, Biochemistry
— id: 74677, year: 2007, vol: 46, page: 12190, stat: Journal Article,

LeuT-Desipramine Structure Reveals How Antidepressants Block Neurotransmitter Reuptake
Zhou, Zheng; Zhen, Juan; Karpowich, Nathan K; Goetz, Regina M; Law, Christopher J; Reith, Maarten E A; Wang, Da-Neng
2007 Sep 7;317(5843):1390-1393, Science
— id: 73794, year: 2007, vol: 317, page: 1390, stat: Journal Article,

Crystal structure and mechanism of GlpT, the glycerol-3-phosphate transporter from E. coli
Lemieux, M Joanne; Huang, Yafei; Wang, Da Neng
2005 ;54 Suppl 1:i43-i46, Journal of electron microscopy
— id: 76453, year: 2005, vol: 54 Suppl 1, page: i43, stat: Journal Article,

Engineering and characterisation of chimeric monoclonal antibody 806 (ch806) for targeted immunotherapy of tumours expressing de2-7 EGFR or amplified EGFR
Panousis, C; Rayzman, V M; Johns, T G; Renner, C; Liu, Z; Cartwright, G; Lee, F-T; Wang, D; Gan, H; Cao, D; Kypridis, A; Smyth, F E; Brechbiel, M W; Burgess, A W; Old, L J; Scott, A M
2005 Mar 28;92(6):1069-1077, British journal of cancer
— id: 144958, year: 2005, vol: 92, page: 1069, stat: Journal Article,

Homology modeling of the human microsomal glucose 6-phosphate transporter explains the mutations that cause the glycogen storage disease type Ib
Almqvist, Jonas; Huang, Yafei; Hovmoller, Sven; Wang, Da-Neng
2004 Jul 27;43(29):9289-9297, Biochemistry
— id: 132719, year: 2004, vol: 43, page: 9289, stat: Journal Article,

Crystal structure and mechanism of the glycerol-3-phosphate transporter from E. coli
Huang, YF; Lemieux, J; Song, JM; Auer, M; Wang, DN
2004 JAN ;86(1):4A-4A, Biophysical journal
— id: 42554, year: 2004, vol: 86, page: 4A, stat: Journal Article,

Electron microscopic analysis of KvAP voltage-dependent K+ channels in an open conformation
Jiang, Qiu-Xing; Wang, Da-Neng; MacKinnon, Roderick
2004 Aug 12;430(7001):806-810, Nature
— id: 132715, year: 2004, vol: 430, page: 806, stat: Journal Article,

Glycerol-3-phosphate transporter of Escherichia coli: structure, function and regulation
Lemieux, M Joanne; Huang, Yafei; Wang, Da-Neng
2004 Oct;155(8):623-629, Research in microbiology
— id: 47902, year: 2004, vol: 155, page: 623, stat: Journal Article,

The structural basis of substrate translocation by the Escherichia coli glycerol-3-phosphate transporter: a member of the major facilitator superfamily
Lemieux, M Joanne; Huang, Yafei; Wang, Da-Neng
2004 Aug;14(4):405-412, Current opinion in structural biology
— id: 48996, year: 2004, vol: 14, page: 405, stat: Journal Article,

"Structural basis for substrate translocation of the escherichia coli glycerol-3-phosphate transporter, GlpT"
Lemieux, MJ; Huang, YF; Song, JM; Auer, M; Wang, DN
2004 OCT 15 ;1658(20):44-44, Biochimica & biophysica acta. Bioentergetics
— id: 46475, year: 2004, vol: 1658, page: 44, stat: Journal Article,

DnaK and DnaJ facilitated the folding process and reduced inclusion body formation of magnesium transporter CorA overexpressed in Escherichia coli
Chen, Yong; Song, Jinmei; Sui, Sen-fang; Wang, Da-Neng
2003 Apr;32(2):221-231, Protein expression & purification
— id: 46249, year: 2003, vol: 32, page: 221, stat: Journal Article,

Structure and mechanism of the glycerol-3-phosphate transporter from Escherichia coli
Huang, Yafei; Lemieux, M Joanne; Song, Jinmei; Auer, Manfred; Wang, Da-Neng
2003 Aug 1;301(5633):616-620, Science
— id: 39121, year: 2003, vol: 301, page: 616, stat: Journal Article,

Three-dimensional crystallization of the Escherichia coli glycerol-3-phosphate transporter: a member of the major facilitator superfamily
Lemieux, M Joanne; Song, Jinmei; Kim, Myong Jin; Huang, Yafei; Villa, Anthony; Auer, Manfred; Li, Xiao-Dan; Wang, Da-Neng
2003 Sep;12(12):2748-2756, Protein science
— id: 46052, year: 2003, vol: 12, page: 2748, stat: Journal Article,

TetL tetracycline efflux protein from Bacillus subtilis is a dimer in the membrane and in detergent solution
Safferling, Markus; Griffith, Heather; Jin, Jie; Sharp, Josh; De Jesus, Magdia; Ng, Caroline; Krulwich, Terry A; Wang, Da-Neng
2003 Mar 5;42(47):13969-13976, Biochemistry
— id: 46259, year: 2003, vol: 42, page: 13969, stat: Journal Article,

Purification and characterization of transporter proteins from human erythrocyte membrane
Wang, Da-Neng; Lemieux, M Joanne; Boulter, Jonathan M
2003 ;228(4 Suppl):239-255, Methods in molecular biology
— id: 39179, year: 2003, vol: 228, page: 239, stat: Journal Article,

Practical aspects of overexpressing bacterial secondary membrane transporters for structural studies
Wang, Da-Neng; Safferling, Markus; Lemieux, M Joanne; Griffith, Heather; Chen, Yong; Li, Xiao-Dan
2003 Feb 17;1610(1):23-36, Biochimica & biophysica acta
— id: 39303, year: 2003, vol: 1610, page: 23, stat: Journal Article,

Importance of detergent and phospholipid in the crystallization of the human erythrocyte anion-exchanger membrane domain
Lemieux, M Joanne; Reithmeier, Reinhart A F; Wang, Da-Neng
2002 Mar;137(3):322-332, Journal of structural biology
— id: 39422, year: 2002, vol: 137, page: 322, stat: Journal Article,

Substrate induced conformational changes of loop 6-7 in the glycerol-3-phosphate transporter
Lemieux, MJ; Auer, M; Wang, DN
2002 JAN ;82(1):569A-569A, Biophysical journal
— id: 55330, year: 2002, vol: 82, page: 569A, stat: Journal Article,

High-Yield Expression and Functional Analysis of Escherichia coli Glycerol-3-phosphate Transporter
Auer M; Kim MJ; Lemieux MJ; Villa A; Song J; Li XD; Wang DN
2001 Jun 5;40(22):6628-6635, Biochemistry
— id: 20638, year: 2001, vol: 40, page: 6628, stat: Journal Article,

Purification and characterization of human erythrocyte glucose transporter in decylmaltoside detergent solution
Boulter JM; Wang DN
2001 Jul;22(2):337-348, Protein expression & purification
— id: 21153, year: 2001, vol: 22, page: 337, stat: Journal Article,

Monomeric state and ligand binding of recombinant GABA transporter from Escherichia coli
Li XD; Villa A; Gownley C; Kim MJ; Song J; Auer M; Wang DN
2001 Apr 13;494(3):165-169, FEBS letters
— id: 20730, year: 2001, vol: 494, page: 165, stat: Journal Article,

Trimeric ring-like structure of ArsA ATPase
Wang HW; Lu YJ; Li LJ; Liu S; Wang DN; Sui S
2000 Mar 3;469(1):105-110, FEBS letters
— id: 57551, year: 2000, vol: 469, page: 105, stat: Journal Article,

Atomic model of plant light-harvesting complex by electron crystallography
Kuhlbrandt W; Wang DN; Fujiyoshi Y
1994 Feb 17;367(6464):614-621, Nature
— id: 57415, year: 1994, vol: 367, page: 614, stat: Journal Article,

Three-dimensional map of the dimeric membrane domain of the human erythrocyte anion exchanger, Band 3
Wang DN; Sarabia VE; Reithmeier RA; Kuhlbrandt W
1994 Jul 15;13(14):3230-3235, EMBO journal
— id: 18532, year: 1994, vol: 13, page: 3230, stat: Journal Article,

Lipid-protein interactions in crystals of plant light-harvesting complex
Nussberger S; Dorr K; Wang DN; Kuhlbrandt W
1993 Nov 20;234(2):347-356, Journal of molecular biology
— id: 18533, year: 1993, vol: 234, page: 347, stat: Journal Article,

Two-dimensional structure of the membrane domain of human band 3, the anion transport protein of the erythrocyte membrane
Wang DN; Kuhlbrandt W; Sarabia VE; Reithmeier RA
1993 Jun;12(6):2233-2239, EMBO journal
— id: 18534, year: 1993, vol: 12, page: 2233, stat: Journal Article,

Three-dimensional structure of plant light-harvesting complex determined by electron crystallography
Kuhlbrandt W; Wang DN
1991 Mar 14;350(6314):130-134, Nature
— id: 57509, year: 1991, vol: 350, page: 130, stat: Journal Article,

High-resolution electron crystallography of light-harvesting chlorophyll a/b-protein complex in three different media
Wang DN; Kuhlbrandt W
1991 Feb 20;217(4):691-699, Journal of molecular biology
— id: 18535, year: 1991, vol: 217, page: 691, stat: Journal Article,