An RNA pyrophosphohydrolase triggers 5' -exonucleolytic degradation of mRNA in Bacillus subtilis.
Ribonuclease J: how to lead a double life.
All things must pass: contrasts and commonalities in eukaryotic and bacterial mRNA decay.
CCR4-NOT deadenylates mRNA associated with RNA-induced silencing complexes in human cells.
A role for huntington disease protein in dendritic RNA granules.
RNase E autoregulates its synthesis in Escherichia coli by binding directly to a stem-loop in the rne 5’ untranslated region.
A new window onto translational repression by bacterial sRNAs.
Importance of translation and nonnucleolytic Ago proteins for on-target RNA interference.
Let me count the ways: mechanisms of gene regulation by miRNAs and siRNAs.
MicroRNAs direct rapid deadenylation of mRNA.
Lost in translation: the influence of ribosomes on bacterial mRNA decay.
MicroRNA regulation of the mammalian lin-28 gene during neuronal differentiation of embryonal carcinoma cells.
Catalytic activation of multimeric RNase E and RNase G by 5'-monophosphorylated RNA.
The function of RNase G in Escherichia coli is constrained by its amino and carboxyl termini.
Two distinct regions on the surface of an RNA-binding domain are crucial for RNase E function.
Critical features of a conserved RNA stem-loop important for feedback regulation of RNase E
Comparative analysis of the plant mRNA-destabilizing element, DST, in mammalian and tobacco cells.
Consequences of RNase E scarity in Escherichia coli.
T7 phage display: a novel genetic selection system for cloing RNA-binding proteins from cDNA libraries.
Structural model for the cooperative assembly of HIV-1 Rev multimers on the RRE as
deducted from analysis of assembly-defective mutants.
An evolutionarily conserved RNA stem-loop functions as a sensor that directs feedback
regulation of RNase E gene expression.
Regions of RNase E important for 5'-end-dependent RNA cleavage and autoregulated
Rapid genetic analysis of RNA-protein interactions by translational
repression in E.coli.
Importance of a 5' stem-loop for longevity of papA mRNA in Escherichia coli.
Target discrimination by RNA-binding proteins: role of the ancillary protein
U2A' and a critical leucine residue in differentiating the RNA-binding specificity
of spliceosomal proteins U1A and U2B".
mRNA stabilization by the ompA 5' untranslated region: two protective
elements hinder distinct pathways for mRNA degradation.
RNA-binding proteins tamed.
RNA recognition by the joint action of two nucleolin RNA-binding
domains: genetic analysis and structural modeling.
A rapid genetic method for the study of RNA binding proteins.
A structural model for the HIV-1 Rev-RRE complex deduced from altered-specificity rev variants isolated by a rapid genetic strategy.
Translation of the adhE transcript to produce ethanol dehydrogenase requires RNase III cleavage in Escherichia coli.
In vitro genetic analysis of RNA-binding proteins using phage display libraries.
Analysis of RNA-binding proteins by in vitro genetic selection: identification of an amino acid residue important for locking U1A onto its RNA target.
The nonamer UUAUUUAUU is the key AU-rich sequence motif that mediates mRNA degradation.
Autoregulation of RNase E synthesis in Escherichia coli.
RNase E autoregulates its synthesis by controlling the degradation rate of its own mRNA in Escherichia coli: unusual sensitivity of the rne transcript to RNase E activity.
The ompA 5' untranslated region impedes a major pathway for mRNA degradation in Escherichia coli.
Multiple elements in the c-fos protein-coding region facilitate mRNA deadenylation and decay by a mechanism coupled to translation.
The destabilizing elements in the coding region of c-fos mRNA are recognized as RNA.
Regulation of proto-oncogene mRNA stability.
Control of RNase E-mediated RNA degradation by 5'-terminal base pairing in E. coli.
A 5'-terminal stem-loop structure can stabilize mRNA in Escherichia coli.
Structure and function of a bacterial mRNA stabilizer: analysis of the 5' untranslated region of ompA mRNA.
Two distinct destabilizing elements in the c-fos message trigger deadenylation as a first step in rapid mRNA decay.
Degradation of pufLMX mRNA in Rhodobacter capsulatus is initiated by nonrandom endonucleolytic cleavage.
The ompA 5' untranslated RNA segment functions in Escherichia coli as a growth-rate-regulated mRNA stabilizer whose activity is unrelated to translational efficiency.
Deadenylylation: a mechanism controlling c-fos mRNA decay.
The c-fos transcript is targeted for rapid decay by two distinct mRNA degradation pathways.
Mechanism of puf mRNA degradation: the role of an intercistronic stem-loop structure.
Mechanisms of mRNA decay in bacteria: a perspective.
An intercistronic stem-loop structure functions as an mRNA decay terminator necessary but insufficient for puf mRNA stability.
Effect of premature termination of translation on mRNA stability depends on the site of ribosome release.
The stability of E. coli gene transcripts is dependent on determinants localized to specific mRNA segments.
Energetics of proline racemase: rates, fractionation factors, and buffer catalysis in the oversaturated region. Nature of the interconversion of the two forms of free enzyme.
Energetics of proline racemase: fractionation factors for the essential catalytic groups in the enzyme-substrate complexes.
Energetics of proline racemase: double fractionation experiment, a test for concertedness and for transition-state dominance.
Energetics of proline racemase: transition-state fractionation factors for the two protons involved in the catalytic steps.
Differential expression of photosynthesis genes in R. capsulata results from segmental differences in stability within the polycistronic rxcA transcript.
Growth-rate dependent regulation of mRNA stability in Escherichia coli.
Decay of mRNA in Escherichia coli: investigation of the fate of specific segments of transcripts.
Polarization of substrate carbonyl groups by yeast aldolase: investigation by Fourier transform infrared spectroscopy.
Beta-lactamase proceeds via an acyl-enzyme intermediate. Interaction of the Escherichia coli RTEM enzyme with cefoxitin.
Beta-lactamase inactivation by mechanism-based reagents.
Direct observation of substrate distortion by triosephosphate isomerase using Fourier transform infrared spectroscopy.
Critical ionization states in the reaction catalyzed by triosephosphate isomerase.
Belasco Lab links