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Betty Bigio, PhD

Research Assistant Professor, Department of Psychiatry

Keywords
Bioinformatics, Computational approaches, Antidepressant drugs, Neurobiology of stress, Depression

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Positions

Research Assistant Professor, Department of Psychiatry at NYU Grossman School of Medicine

Graduate Education

PhD from University of Paris

Insulin receptor substrate in brain-enriched exosomes in subjects with major depression: on the path of creation of biosignatures of central insulin resistance

Nasca, Carla; Dobbin, Josh; Bigio, Benedetta; Watson, Kathleen; de Angelis, Paolo; Kautz, Marin; Cochran, Ashly; Mathé, Aleksander A; Kocsis, James H; Lee, Francis S; Murrough, James W; McEwen, Bruce S; Rasgon, Natalie

Molecular psychiatry. 2021 Sep; 26(9):5140-5149

Epigenetics and energetics in ventral hippocampus mediate rapid antidepressant action: Implications for treatment resistance

Bigio, Benedetta; Mathé, Aleksander A; Sousa, Vasco C; Zelli, Danielle; Svenningsson, Per; McEwen, Bruce S; Nasca, Carla

Proceedings of the National Academy of Sciences of the United States of America (PNAS). 2016 07 12; 113(28):7906-11

Mind the gap: glucocorticoids modulate hippocampal glutamate tone underlying individual differences in stress susceptibility

Nasca, C; Bigio, B; Zelli, D; Nicoletti, F; McEwen, B S

Molecular psychiatry. 2015 Jun; 20(6):755-63

Multidimensional predictors of antidepressant responses: Integrating mitochondrial, genetic, metabolic and environmental factors with clinical outcomes

Nasca, Carla; Barnhill, Olivia; DeAngelis, Paolo; Watson, Kathleen; Lin, Jue; Beasley, James; Young, Sarah P; Myoraku, Alison; Dobbin, Josh; Bigio, Benedetta; McEwen, Bruce; Rasgon, Natalie

Neurobiology of stress. 2021 Nov; 15:100407

Multidimensional Predictors of Susceptibility and Resilience to Social Defeat Stress

Nasca, Carla; Menard, Caroline; Hodes, Georgia; Bigio, Benedetta; Pena, Catherine; Lorsch, Zachary; Zelli, Danielle; Ferris, Anjali; Kana, Veronika; Purushothaman, Immanuel; Dobbin, Josh; Nassim, Marouane; DeAngelis, Paolo; Merad, Miriam; Rasgon, Natalie; Meaney, Michael; Nestler, Eric J; McEwen, Bruce S; Russo, Scott J

Biological psychiatry. 2019 09 15; 86(6):483-491

Role of the Astroglial Glutamate Exchanger xCT in Ventral Hippocampus in Resilience to Stress

Nasca, Carla; Bigio, Benedetta; Zelli, Danielle; de Angelis, Paolo; Lau, Timothy; Okamoto, Masahiro; Soya, Hideyo; Ni, Jason; Brichta, Lars; Greengard, Paul; Neve, Rachael L; Lee, Francis S; McEwen, Bruce S

Neuron. 2017 Oct 11; 96(2):402-413.e5

Stress-induced structural plasticity of medial amygdala stellate neurons and rapid prevention by a candidate antidepressant

Lau, T; Bigio, B; Zelli, D; McEwen, B S; Nasca, C

Molecular psychiatry. 2017 02; 22(2):227-234

Acetyl-l-carnitine deficiency in patients with major depressive disorder

Nasca, Carla; Bigio, Benedetta; Lee, Francis S; Young, Sarah P; Kautz, Marin M; Albright, Ashly; Beasley, James; Millington, David S; Mathé, Aleksander A; Kocsis, James H; Murrough, James W; McEwen, Bruce S; Rasgon, Natalie

Proceedings of the National Academy of Sciences of the United States of America (PNAS). 2018 08 21; 115(34):8627-8632

See All Publications (43)