Cannabinoids for the Treatment of Epilepsy

Friday, June 26, 2015

This one day course will provide an update on the latest basic and clinical science on the use cannabinoids, including cannabidiol (CBD), the nonpsychoactive component of cannabis, and medical marijuana in the treatment of epilepsy.  Recent anecdotal evidence and studies in animal models of the disease suggests that cannabinoids may be a promising therapy for epilepsy.  Many states, including New York, have recently approved the use of cannabis and cannabis-based products for the treatment of many conditions, including seizures.  Using a didactic format, we will review the pharmacology and neurobiology of cannabinoids with a special focus on mechanisms that may act on seizures.  We will also review the pre-clinical and clinical evidence for efficacy.  Finally, we will review the results of early experience of CBD and medical marijuana preparations for the treatment of severe pediatric epilepsy.  Round-table discussions will focus on highlighting knowledge gaps and next steps forward for clinical investigation and practice.