Xue-Ru Wu, M.D.

Aristolochic acid-associated urothelial cancer in Taiwan
Chen, CH; Dickman, KG; Moriya, M; Zavadil, J; Sidorenko, VS; Edwards, KL; Gnatenko, DV; Wu, L; Turesky, RJ; Wu, XR; Pu, YS; Grollman, AP
2012 Apr;:8241-8246, Proceedings of the National Academy of Sciences of the United States of America
— id: 164510, year: 2012, vol: , page: 8241, stat: Journal Article,

Uromodulin in Kidney Injury: An Instigator, Bystander, or Protector?
El-Achkar TM; Wu XR
2012 Jan 23;:452-461 #, American journal of kidney diseases
— id: 150549, year: 2012, vol: , page: 452, stat: Journal Article,

Tissue-specific mutagenesis by N-butyl-N-(4-hydroxybutyl)nitrosamine as the basis for urothelial carcinogenesis
He, Zhiming; Kosinska, Wieslawa; Zhao, Zhong-Lin; Wu, Xue-Ru; Guttenplan, Joseph B
2012 Feb;742(1-2):92-95, Mutation research
— id: 156491, year: 2012, vol: 742, page: 92, stat: Journal Article,

Regulation of a novel androgen receptor target gene, cyclin B1, through androgen-dependent E2F family member switching
Li, Y; Zhang, DY; Ren, Q; Ye, F; Zhao, X; Daniels, G; Wu, X; Dynlacht, B; Lee, P
2012 Apr;:?-?, Molecular & cellular biology
— id: 164476, year: 2012, vol: , page: ?, stat: Journal Article,

E3 Ligase Activity of XIAP RING Domain Is Required for XIAP-Mediated Cancer Cell Migration, but Not for Its RhoGDI Binding Activity
Liu, Jinyi; Zhang, Dongyun; Luo, Wenjing; Yu, Jianxiu; Li, Jingxia; Yu, Yonghui; Zhang, Xinhai; Chen, Jingyuan; Wu, Xue-Ru; Huang, Chuanshu
2012 ;7(4):e35682-e35682 e35682, PLoS ONE
— id: 165633, year: 2012, vol: 7, page: e35682, stat: Journal Article,

Tamm-Horsfall protein regulates circulating and renal cytokines by affecting glomerular filtration rate and acting as a urinary cytokine trap
Liu, Y; El-Achkar, TM; Wu, XR
2012 Mar;:16365-16378, Journal of biological chemistry
— id: 162338, year: 2012, vol: , page: 16365, stat: Journal Article,

Molecular and cellular effects of Tamm-Horsfall protein mutations and their rescue by chemical chaperones
Ma L; Liu Y; El-Achkar TM; Wu XR
2012 Jan;287(2):1290-1305, Journal of biological chemistry
— id: 145778, year: 2012, vol: 287, page: 1290, stat: Journal Article,

Effect of carcinogenic acrolein on DNA repair and mutagenic susceptibility
Wang HT; Hu Y; Tong D; Huang J; Gu L; Wu XR; Chung FL; Li GM; Tang MS
2012 Jan 24;:12379-12386 #, Journal of biological chemistry
— id: 150550, year: 2012, vol: , page: 12379, stat: Journal Article,

Defects in the endoderm survival and polarity of cell divisions in the mouse model for rectourethral malformations
Xu, K.; Wu, X.; Shapiro, E.; Huang, H.; Zhang, L.; Deng, Y.; Mandelshtam, V; Li, J.; Lepor, H.; Grishina, I. B.
2012 FEB;11(1):E812-U719, European Urology Supplements
— id: 166869, year: 2012, vol: 11, page: E812, stat: Journal Article,

RhoGDI SUMOylation at K138 Increases Its Binding Activity to Rho GTPase and its Inhibiting Cancer Cell Motility
Yu, J; Zhang, D; Liu, J; Li, J; Yu, Y; Wu, XR; Huang, C
2012 Mar;:13752-13760, Journal of biological chemistry
— id: 162339, year: 2012, vol: , page: 13752, stat: Journal Article,

Urothelial tumor initiation requires deregulation of multiple signaling pathways: implications in target-based therapies
Zhou, H; Huang, HY; Shapiro, E; Lepor, H; Huang, WC; Mohammadi, M; Mohr, I; Tang, MS; Huang, C; Wu, XR
2012 Feb;:770-780, Carcinogenesis
— id: 162340, year: 2012, vol: , page: 770, stat: Journal Article,

K-Ras and {beta}-catenin mutations cooperate with Fgfr3 mutations in mice to promote tumorigenesis in the skin and lung, but not in the bladder
Ahmad I; Singh LB; Foth M; Morris CA; Taketo MM; Wu XR; Leung HY; Sansom OJ; Iwata T
2011 Jul-Aug;4(4):548-555, Disease models & mechanisms
— id: 131662, year: 2011, vol: 4, page: 548, stat: Journal Article,

beta-Catenin activation synergizes with PTEN loss to cause bladder cancer formation
Ahmad, I; Morton, J P; Singh, L B; Radulescu, S M; Ridgway, R A; Patel, S; Woodgett, J; Winton, D J; Taketo, M M; Wu, X-R; Leung, H Y; Sansom, O J
2011 Jan 13;30(2):178-189, Oncogene
— id: 132742, year: 2011, vol: 30, page: 178, stat: Journal Article,

Ras mutation cooperates with beta-catenin activation to drive bladder tumourigenesis
Ahmad, I; Patel, R; Liu, Y; Singh, L B; Taketo, M M; Wu, X-R; Leung, H Y; Sansom, O J
2011 ;2:e124-e124, Cell death & disease
— id: 132242, year: 2011, vol: 2, page: e124, stat: Journal Article,

Tamm-Horsfall Protein Deficient Thick Ascending Limbs Promote Injury to Neighboring S3 Segments in an MIP-2 Dependent Mechanism
El-Achkar TM; McCracken R; Rauchman M; Heitmeier MR; Al-Aly Z; Dagher PC; Wu XR
2011 Apr;300(4):F999-F1007, American journal of physiology. Renal physiology
— id: 120836, year: 2011, vol: 300, page: F999, stat: Journal Article,

Organ, species and sex differences in mutagenesis induced by butyl-hydroxybutyl-N-nitrosamine in big blue transgenic rodents as the basis for the strict organ specificity of this environmental carcinogen metabolite
He, Z; Strasberg-Rieber, Z -L Z; Kosinska, W; Wu, X -R; Guttenplan, J B
2011 15 Apr 2011;71(8):-, Cancer research
— id: 162905, year: 2011, vol: 71, page: , stat: Journal Article,

The X-linked inhibitor of apoptosis protein (XIAP) mediates cancer cell motility Via RhoGDP dissociation inhibitor (RhoGDI)-dependent regulation of cytoskeleton
Liu J; Zhang D; Luo W; Yu Y; Yu J; Li J; Zhang X; Zhang B; Chen J; Wu XR; Rosas-Acosta G; Huang C
2011 May 6;286(18):15630-15640, Journal of biological chemistry
— id: 131663, year: 2011, vol: 286, page: 15630, stat: Journal Article,

The epithelium-molecular landscaping for an interactive barrier
Chai, Karl; Kitamura, Kenichiro; McCann, Amanda; Wu, Xue-Ru
2010 ;2010:870506-870506, Journal of biomedicine & biotechnology
— id: 132737, year: 2010, vol: 2010, page: 870506, stat: Journal Article,

Comparison of the pathology of interstitial plaque in human ICSF stone patients to NHERF-1 and THP-null mice
Evan, Andrew P; Weinman, Edward J; Wu, Xue-Ru; Lingeman, James E; Worcester, Elaine M; Coe, Fredric L
2010 Dec;38(6):439-452, Urological research
— id: 132736, year: 2010, vol: 38, page: 439, stat: Journal Article,

Progressive renal papillary calcification and ureteral stone formation in mice deficient for Tamm-Horsfall protein
Liu, Yan; Mo, Lan; Goldfarb, David S; Evan, Andrew P; Liang, Fengxia; Khan, Saeed R; Lieske, John C; Wu, Xue-Ru
2010 Sep;299(3):F469-F478, American journal of physiology. Renal physiology
— id: 138204, year: 2010, vol: 299, page: F469, stat: Journal Article,

Neuropilin-VEGF signaling pathway acts as a key modulator of vascular, lymphatic, and inflammatory cell responses of the bladder to intravesical BCG treatment
Saban, Marcia R; Sferra, Thomas J; Davis, Carole A; Simpson, Cindy; Allen, Arielle; Maier, Julie; Fowler, Ben; Knowlton, Nicholas; Birder, Lori; Wu, Xue-Ru; Saban, Ricardo
2010 Dec;299(6):F1245-F1256, American journal of physiology. Renal physiology
— id: 132735, year: 2010, vol: 299, page: F1245, stat: Journal Article,

Utility of Uroplakin and PAX-2 Immunohistochemistry in the Diagnosis of Primary Adenocarcinoma of the Urinary Bladder
Ye, H; Wu, X; Hansel, DE; Melamed, J; Epstein, JI
2010 FEB ;23(3):229A-230A, Modern pathology
— id: 109937, year: 2010, vol: 23, page: 229A, stat: Journal Article,

Utility of Uroplakin and PAX-2 Immunohistochemistry in the Diagnosis of Primary Adenocarcinoma of the Urinary Bladder
Ye, H; Wu, X; Hansel, DE; Melamed, J; Epstein, JI
2010 FEB ;90(11):229A-230A, Laboratory investigation
— id: 109956, year: 2010, vol: 90, page: 229A, stat: Journal Article,

Temporally and spatially controllable gene expression and knockout in mouse urothelium
Zhou, Haiping; Liu, Yan; He, Feng; Mo, Lan; Sun, Tung-Tien; Wu, Xue-Ru
2010 Aug;299(2):F387-F395, American journal of physiology. Renal physiology
— id: 138180, year: 2010, vol: 299, page: F387, stat: Journal Article,

Deficiency of pRb family proteins and p53 in invasive urothelial tumorigenesis
He, Feng; Mo, Lan; Zheng, Xiao-Yong; Hu, Changkun; Lepor, Herbert; Lee, Eva Y-H P; Sun, Tung-Tien; Wu, Xue-Ru
2009 Dec 15;69(24):9413-9421, Cancer research
— id: 105925, year: 2009, vol: 69, page: 9413, stat: Journal Article,

Immunohistochemical Panel to Identify the Primary Site of Invasive Micropapillary Carcinoma
Lotan, Tamara L; Ye, Huihui; Melamed, Jonathan; Wu, Xue-Ru; Shih, Ie-Ming; Epstein, Jonathan I
2009 Jul;33(7):1037-1041, American journal of surgical pathology
— id: 95436, year: 2009, vol: 33, page: 1037, stat: Journal Article,

Biology of urothelial tumorigenesis: insights from genetically engineered mice
Wu, Xue-Ru
2009 Dec;28(3-4):281-290, Cancer metastasis reviews
— id: 106275, year: 2009, vol: 28, page: 281, stat: Journal Article,

Uroplakins in urothelial biology, function, and disease
Wu, Xue-Ru; Kong, Xiang-Peng; Pellicer, Angel; Kreibich, Gert; Sun, Tung-Tien
2009 Jun;75(11):1153-1165, Kidney international
— id: 98907, year: 2009, vol: 75, page: 1153, stat: Journal Article,

Tamm-Horsfall protein protects the kidney from ischemic injury by decreasing inflammation and altering TLR4 expression
El-Achkar, Tarek M; Wu, Xue-Ru; Rauchman, Michael; McCracken, Ruth; Kiefer, Susan; Dagher, Pierre C
2008 Aug;295(2):F534-F544, American journal of physiology. Renal physiology
— id: 132739, year: 2008, vol: 295, page: F534, stat: Journal Article,

VEGF receptors and neuropilins are expressed in the urothelial and neuronal cells in normal mouse urinary bladder and are upregulated in inflammation
Saban, Marcia R; Backer, Joseph M; Backer, Marina V; Maier, Julie; Fowler, Ben; Davis, Carole A; Simpson, Cindy; Wu, Xue-Ru; Birder, Lori; Freeman, Michael R; Soker, Shay; Hurst, Robert E; Saban, Ricardo
2008 Jul;295(1):F60-F72, American journal of physiology. Renal physiology
— id: 132740, year: 2008, vol: 295, page: F60, stat: Journal Article,

Molecular networks discriminating mouse bladder responses to intravesical bacillus Calmette-Guerin (BCG), LPS, and TNF-alpha
Saban, Marcia R; O'Donnell, Michael A; Hurst, Robert E; Wu, Xue-Ru; Simpson, Cindy; Dozmorov, Igor; Davis, Carole; Saban, Ricardo
2008 ;9:4-4, BMC Immunology
— id: 132741, year: 2008, vol: 9, page: 4, stat: Journal Article,

Urothelial expression of neuropilins and VEGF receptors in control and interstitial cystitis patients
Saban, Ricardo; Saban, Marcia R; Maier, Julie; Fowler, Ben; Tengowski, Mark; Davis, Carole A; Wu, Xue-Ru; Culkin, Daniel J; Hauser, Paul; Backer, Joseph; Hurst, Robert E
2008 Dec;295(6):F1613-F1623, American journal of physiology. Renal physiology
— id: 132738, year: 2008, vol: 295, page: F1613, stat: Journal Article,

Oncogene-induced replication stress preferentially targets common fragile sites in preneoplastic lesions. A genome-wide study
Tsantoulis, P K; Kotsinas, A; Sfikakis, P P; Evangelou, K; Sideridou, M; Levy, B; Mo, L; Kittas, C; Wu, X-R; Papavassiliou, A G; Gorgoulis, V G
2008 May 22;27(23):3256-3264, Oncogene
— id: 75193, year: 2008, vol: 27, page: 3256, stat: Journal Article,

Loss of Urinary Macromolecules in Mice Causes Interstitial and Intratubular Renal Calcification Dependent on the Underlying Conditions
Wu, XR; Lieske, JC; Evan, AP; Sommer, AJ; Liaw, L; Mo, L
2008 NOV 25 ;1049(22):113-119, AIP conference proceedings
— id: 91289, year: 2008, vol: 1049, page: 113, stat: Journal Article,

The histone deacetylase inhibitor belinostat (PXD101) suppresses bladder cancer cell growth in vitro and in vivo
Buckley, Michael T; Yoon, Joanne; Yee, Herman; Chiriboga, Luis; Liebes, Leonard; Ara, Gulshan; Qian, Xiaozhong; Bajorin, Dean F; Sun, Tung-Tien; Wu, Xue-Ru; Osman, Iman
2007 Oct 12;5(1):49-49, Journal of translational medicine
— id: 74320, year: 2007, vol: 5, page: 49, stat: Journal Article,

Persistent uroplakin expression in advanced urothelial carcinomas: implications in urothelial tumor progression and clinical outcome
Huang, Hong-Ying; Shariat, Shahrokh F; Sun, Tung-Tien; Lepor, Herbert; Shapiro, Ellen; Hsieh, Jer-Tsong; Ashfaq, Raheela; Lotan, Yair; Wu, Xue-Ru
2007 Nov;38(11):1703-1713, Human pathology
— id: 73404, year: 2007, vol: 38, page: 1703, stat: Journal Article,

Decreased DOC-2/DAB2 expression in urothelial carcinoma of the bladder
Karam, Jose A; Shariat, Shahrokh F; Huang, Hong-Ying; Pong, Rey-Chen; Ashfaq, Raheela; Shapiro, Ellen; Lotan, Yair; Sagalowsky, Arthur I; Wu, Xue-Ru; Hsieh, Jer-Tsong
2007 Aug 1;13(15 Pt 1):4400-4406, Clinical cancer research
— id: 73405, year: 2007, vol: 13, page: 4400, stat: Journal Article,

Renal Calcinosis and Stone Formation in Mice Lacking Osteopontin, Tamm-Horsfall Protein or Both
Mo, Lan; Liaw, Lucy; Evan, Andrew P; Sommer, Andre J; Lieske, John C; Wu, Xue-Ru
2007 Dec;293(6):F1935-F1943, American journal of physiology. Renal physiology
— id: 74321, year: 2007, vol: 293, page: F1935, stat: Journal Article,

Hyperactivation of Ha-ras oncogene, but not Ink4a/Arf deficiency, triggers bladder tumorigenesis
Mo, Lan; Zheng, Xiaoyong; Huang, Hong-Ying; Shapiro, Ellen; Lepor, Herbert; Cordon-Cardo, Carlos; Sun, Tung-Tien; Wu, Xue-Ru
2007 Feb 1;117(2):314-325, Journal of clinical investigation
— id: 70641, year: 2007, vol: 117, page: 314, stat: Journal Article,

Repeated BCG treatment of mouse bladder selectively stimulates small GTPases and HLA antigens and inhibits single-spanning uroplakins
Saban, Marcia R; Hellmich, Helen L; Simpson, Cindy; Davis, Carole A; Lang, Mark L; Ihnat, Michael A; O'Donnell, Michael A; Wu, Xue-Ru; Saban, Ricardo
2007 Nov 2;7(1):204-204, BMC cancer
— id: 75191, year: 2007, vol: 7, page: 204, stat: Journal Article,

Lymphatic vessel density and function in experimental bladder cancer
Saban, Marcia R; Towner, Rheal; Smith, Nataliya; Abbott, Andrew; Neeman, Michal; Davis, Carole A; Simpson, Cindy; Maier, Julie; Memet, Sylvie; Wu, Xue-Ru; Saban, Ricardo
2007 Nov 29;7(1):219-219, BMC cancer
— id: 75190, year: 2007, vol: 7, page: 219, stat: Journal Article,

Early detection and measurement of urothelial tumors in mice
Johnson, Aimee M; Conover, David L; Huang, Jiaoti; Messing, Edward M; Ning, Ruola; O'Connell, Mary J; Rossi, M Adrian; Sun, Tung-Tien; Wood, Ronald W; Wu, Xue-Ru; Reeder, Jay E
2006 Jun;67(6):1309-1314, Urology
— id: 66475, year: 2006, vol: 67, page: 1309, stat: Journal Article,

Gene deletion in urothelium by specific expression of Cre recombinase
Mo L; Cheng J; Lee EY; Sun TT; Wu XR
2006 ;175(4):1569-, Journal of urology
— id: 62773, year: 2006, vol: 175, page: 1569, stat: Journal Article,

Distinct glycan structures of uroplakins Ia and Ib: structural basis for the selective binding of FimH adhesin to uroplakin Ia
Xie, Bo; Zhou, Ge; Chan, Shiu-Yung; Shapiro, Ellen; Kong, Xiang-Peng; Wu, Xue-Ru; Sun, Tung-Tien; Costello, Catherine E
2006 May 26;281(21):14644-14653, Journal of biological chemistry
— id: 66476, year: 2006, vol: 281, page: 14644, stat: Journal Article,

Differential expression of cell cycle regulators in phenotypic variants of transgenically induced bladder tumors: implications for tumor behavior
Garcia-Espana, Antonio; Salazar, Edgard; Sun, Tung-Tien; Wu, Xue-Ru; Pellicer, Angel
2005 Feb 15;65(4):1150-1157, Cancer research
— id: 48701, year: 2005, vol: 65, page: 1150, stat: Journal Article,

Cellular basis of urothelial squamous metaplasia: roles of lineage heterogeneity and cell replacement
Liang, Feng-Xia; Bosland, Maarten C; Huang, Hongying; Romih, Rok; Baptiste, Solange; Deng, Fang-Ming; Wu, Xue-Ru; Shapiro, Ellen; Sun, Tung-Tien
2005 Dec 5;171(5):835-844, Journal of cell biology
— id: 59934, year: 2005, vol: 171, page: 835, stat: Journal Article,

Gene Deletion in Urothelium by Specific Expression of Cre Recombinase
Mo, Lan; Cheng, Jin; Lee, Eva Y-H P; Sun, Tung-Tien; Wu, Xue-Ru
2005 Apr 19;289(3):F562-F568, American journal of physiology. Renal physiology
— id: 51116, year: 2005, vol: 289, page: F562, stat: Journal Article,

Urothelial umbrella cells of human ureter are heterogeneous with respect to their uroplakin composition: different degrees of urothelial maturity in ureter and bladder?
Riedel, Ina; Liang, Feng-Xia; Deng, Fang-Ming; Tu, Liyu; Kreibich, Gert; Wu, Xue-Ru; Sun, Tung-Tien; Hergt, Michaela; Moll, Roland
2005 Mar;84(2-3):393-405, European journal of cell biology
— id: 51032, year: 2005, vol: 84, page: 393, stat: Journal Article,

A survivin gene signature predicts aggressive tumor behavior
Salz, Whitney; Eisenberg, Dan; Plescia, Janet; Garlick, David S; Weiss, Robert M; Wu, Xue-Ru; Sun, Tung-Tien; Altieri, Dario C
2005 May 1;65(9):3531-3534, Cancer research
— id: 51752, year: 2005, vol: 65, page: 3531, stat: Journal Article,

IMMUNOLOCALIZATION OF ESTROGEN RECEPTOR alpha AND beta IN HUMAN FETAL PROSTATE
Shapiro, Ellen; Huang, Hongying; Masch, Rachel J; McFadden, Deborah E; Wilson, E Lynette; Wu, Xue-Ru
2005 Nov;174(5):2051-2053, Journal of urology
— id: 58459, year: 2005, vol: 174, page: 2051, stat: Journal Article,

IMMUNOLOCALIZATION OF ANDROGEN RECEPTOR AND ESTROGEN RECEPTORS alpha AND beta IN HUMAN FETAL TESTIS AND EPIDIDYMIS
Shapiro, Ellen; Huang, Hongying; Masch, Rachel J; McFadden, Deborah E; Wu, Xue-Ru; Ostrer, Harry
2005 Oct;174(4, Part 2 of 2):1695-1698, Journal of urology
— id: 57793, year: 2005, vol: 174, page: 1695, stat: Journal Article,

Urothelial tumorigenesis: a tale of divergent pathways
Wu, Xue-Ru
2005 Sep;5(9):713-725, Nature reviews. Cancer
— id: 57725, year: 2005, vol: 5, page: 713, stat: Journal Article,

Variation of high mannose chains of Tamm-Horsfall glycoprotein confers differential binding to type 1-fimbriated Escherichia coli
Cavallone, Daniela; Malagolini, Nadia; Monti, Angela; Wu, Xue-Ru; Serafini-Cessi, Franca
2004 Jan 2;279(1):216-222, Journal of biological chemistry
— id: 42020, year: 2004, vol: 279, page: 216, stat: Journal Article,

p53 deficiency provokes urothelial proliferation and synergizes with activated Ha-ras in promoting urothelial tumorigenesis
Gao, Jing; Huang, Hong-Ying; Pak, Joanne; Cheng, Jin; Zhang, Zhong-Ting; Shapiro, Ellen; Pellicer, Angel; Sun, Tung-Tien; Wu, Xue-Ru
2004 Jan 22;23(3):687-696, Oncogene
— id: 42019, year: 2004, vol: 23, page: 687, stat: Journal Article,

Lack of major involvement of human uroplakin genes in vesicoureteral reflux: Implications for disease heterogeneity
Jiang, Songshan; Gitlin, Jordan; Deng, Fang-Ming; Liang, Feng-Xia; Lee, Andy; Atala, Anthony; Bauer, Stuart B; Ehrlich, Garth D; Feather, Sally A; Goldberg, Judith D; Goodship, Judith A; Goodship, Timothy H J; Hermanns, Monika; Hu, Fen Ze; Jones, Katrin E; Malcolm, Sue; Mendelsohn, Cathy; Preston, Robert A; Retik, Alan B; Schneck, Francis X; Wright, Victoria; Ye, Xiang Y; Woolf, Adrian S; Wu, Xue-Ru; Ostrer, Harry; Shapiro, Ellen; Yu, Jun; Sun, Tung-Tien
2004 Jul;66(1):10-19, Kidney international
— id: 43158, year: 2004, vol: 66, page: 10, stat: Journal Article,

Tamm-Horsfall protein is a critical renal defense factor protecting against calcium oxalate crystal formation
Mo, Lan; Huang, Hong-Ying; Zhu, Xin-Hua; Shapiro, Ellen; Hasty, David L; Wu, Xue-Ru
2004 Sep;66(3):1159-1166, Kidney international
— id: 44481, year: 2004, vol: 66, page: 1159, stat: Journal Article,

Ablation of the Tamm-Horsfall protein gene increases susceptibility of mice to bladder colonization by type 1-fimbriated Escherichia coli
Mo, Lan; Zhu, Xin-Hua; Huang, Hong-Ying; Shapiro, Ellen; Hasty, David L; Wu, Xue-Ru
2004 Apr;286(4):F795-F802, American journal of physiology. Renal physiology
— id: 48190, year: 2004, vol: 286, page: F795, stat: Journal Article,

Detection of circulating cancer cells expressing uroplakins and epidermal growth factor receptor in bladder cancer patients
Osman, Iman; Kang, Melissa; Lee, Andy; Deng, Fang-Ming; Polsky, David; Mikhail, Maryann; Chang, Caroline; David, Dexter A; Mitra, Nandita; Wu, Xue-Ru; Sun, Tung-Tien; Bajorin, Dean F
2004 Oct 10;111(6):934-939, International journal of cancer
— id: 44185, year: 2004, vol: 111, page: 934, stat: Journal Article,

THE PROSTATIC UTRICLE IS NOT A MULLERIAN DUCT REMNANT: IMMUNOHISTOCHEMICAL EVIDENCE FOR A DISTINCT UROGENITAL SINUS ORIGIN
Shapiro, Ellen; Huang, Hongying; McFadden, Deborah E; Masch, Rachel J; Ng, Eliza; Lepor, Herbert; Wu, Xue-Ru
2004 Oct;172(4, Part 2 Of 2):1753-1756, Journal of urology
— id: 44930, year: 2004, vol: 172, page: 1753, stat: Journal Article,

New concepts on the development of the vagina
Shapiro, Ellen; Huang, Hongying; Wu, Xue-Ru
2004 ;545(1):173-185, Advances in experimental medicine & biology
— id: 42301, year: 2004, vol: 545, page: 173, stat: Journal Article,

Allelic loss of p53 gene is associated with genesis and maintenance, but not invasion, of mouse carcinoma in situ of the bladder
Cheng, Jin; Huang, Hongying; Pak, Joanne; Shapiro, Ellen; Sun, Tung-Tien; Cordon-Cardo, Carlos; Waldman, Frederic M; Wu, Xue-Ru
2003 Jan 1;63(1):179-185, Cancer research
— id: 34168, year: 2003, vol: 63, page: 179, stat: Journal Article,

Renal tubule-specific expression and urinary secretion of human hormone: a kidney-based transgenic bioreactor growth
Zhu, Xinhua; Cheng, Jin; Huang, Liwei; Gao, Jin; Zhang, Zhong-Ting; Pak, Joanne; Wu, Xue-Ru
2003 Apr;12(2):155-162, Transgenic research
— id: 39231, year: 2003, vol: 12, page: 155, stat: Journal Article,

The human prostate expresses sonic hedgehog during fetal development
Barnett, Daniel H; Huang, Hong-Ying; Wu, Xue-Ru; Laciak, Robert; Shapiro, Ellen; Bushman, Wade
2002 Nov;168(5):2206-2210, Journal of urology
— id: 75192, year: 2002, vol: 168, page: 2206, stat: Journal Article,

Overexpression of epidermal growth factor receptor in urothelium elicits urothelial hyperplasia and promotes bladder tumor growth
Cheng, Jin; Huang, Hongying; Zhang, Zhong-Ting; Shapiro, Ellen; Pellicer, Angel; Sun, Tung-Tien; Wu, Xue-Ru
2002 Jul 15;62(14):4157-4163, Cancer research
— id: 32471, year: 2002, vol: 62, page: 4157, stat: Journal Article,

Isolation of mouse THP gene promoter and demonstration of its kidney-specific activity in transgenic mice
Zhu, Xinhua; Cheng, Jin; Gao, Jing; Lepor, Herbert; Zhang, Zhong-Ting; Pak, Joanne; Wu, Xue-Ru
2002 Apr;282(4):F608-F617, American journal of physiology. Renal physiology
— id: 39700, year: 2002, vol: 282, page: F608, stat: Journal Article,

Ablation of uroplakin III gene results in small urothelial plaques, urothelial leakage, and vesicoureteral reflux
Hu P; Deng F; Liang F; Hu C; Auerbach A; Shapiro E; Wu X; Kachar B; Sun T
2001 Jun;57(6 Suppl 1):117-117, Urology
— id: 21194, year: 2001, vol: 57, page: 117, stat: Journal Article,

Organization of uroplakin subunits: transmembrane topology, pair formation and plaque composition
Liang FX; Riedel I; Deng FM; Zhou G; Xu C; Wu XR; Kong XP; Moll R; Sun TT
2001 Apr 1;355(Pt 1):13-18, Biochemical journal
— id: 21231, year: 2001, vol: 355, page: 13, stat: Journal Article,

Tamm-Horsfall protein binds to type 1 fimbriated Escherichia coli and prevents E. coli from binding to uroplakin Ia and Ib receptors
Pak J; Pu Y; Zhang ZT; Hasty DL; Wu XR
2001 Mar 30;276(13):9924-9930, Journal of biological chemistry
— id: 26762, year: 2001, vol: 276, page: 9924, stat: Journal Article,

Brenner tumors but not transitional cell carcinomas of the ovary show urothelial differentiation: immunohistochemical staining of urothelial markers, including cytokeratins and uroplakins
Riedel I; Czernobilsky B; Lifschitz-Mercer B; Roth LM; Wu XR; Sun TT; Moll R
2001 Feb;438(2):181-191, Virchows archive
— id: 26905, year: 2001, vol: 438, page: 181, stat: Journal Article,

Role of Ha-ras activation in superficial papillary pathway of urothelial tumor formation
Zhang ZT; Pak J; Huang HY; Shapiro E; Sun TT; Pellicer A; Wu XR
2001 Apr 12;20(16):1973-1980, Oncogene
— id: 20658, year: 2001, vol: 20, page: 1973, stat: Journal Article,

Uroplakin Ia is the urothelial receptor for uropathogenic Escherichia coli: evidence from in vitro FimH binding
Zhou G; Mo WJ; Sebbel P; Min G; Neubert TA; Glockshuber R; Wu XR; Sun TT; Kong XP
2001 Nov;114(Pt 22):4095-4103, Journal of cell science
— id: 26903, year: 2001, vol: 114, page: 4095, stat: Journal Article,

Ablation of uroplakin III gene results in small urothelial plaques, urothelial leakage, and vesicoureteral reflux
Hu P; Deng FM; Liang FX; Hu CM; Auerbach AB; Shapiro E; Wu XR; Kachar B; Sun TT
2000 Nov 27;151(5):961-972, Journal of cell biology
— id: 26906, year: 2000, vol: 151, page: 961, stat: Journal Article,

Terminal glycosylation of bovine uroplakin III, one of the major integral-membrane glycoproteins of mammalian bladder
Malagolini N; Cavallone D; Wu XR; Serafini-Cessi F
2000 Jul 26;1475(3):231-237, Biochimica & biophysica acta
— id: 34164, year: 2000, vol: 1475, page: 231, stat: Journal Article,

Uroplakin and androgen receptor expression in the human fetal genital tract: insights into the development of the vagina
Shapiro E; Huang HY; Wu XR
2000 Sep;164(3 Pt 2):1048-1051, Journal of urology
— id: 11531, year: 2000, vol: 164, page: 1048, stat: Journal Article,

New concepts of histological changes in experimental augmentation cystoplasty: insights into the development of neoplastic transformation at the enterovesical and gastrovesical anastomosis
Gitlin JS; Wu XR; Sun TT; Ritchey ML; Shapiro E
1999 Sep;162(3 Pt 2):1096-1100, Journal of urology
— id: 11968, year: 1999, vol: 162, page: 1096, stat: Journal Article,

Three-dimensional analysis of the 16 nm urothelial plaque particle: luminal surface exposure, preferential head-to-head interaction, and hinge formation
Kachar B; Liang F; Lins U; Ding M; Wu XR; Stoffler D; Aebi U; Sun TT
1999 Jan 15;285(2):595-608, Journal of molecular biology
— id: 7961, year: 1999, vol: 285, page: 595, stat: Journal Article,

Detection of circulating uroplakin-positive cells in patients with transitional cell carcinoma of the bladder
Li SM; Zhang ZT; Chan S; McLenan O; Dixon C; Taneja S; Lepor H; Sun TT; Wu XR
1999 Sep;162(3 Pt 1):931-935, Journal of urology
— id: 6182, year: 1999, vol: 162, page: 931, stat: Journal Article,

Urothelial hinge as a highly specialized membrane: detergent-insolubility, urohingin association, and in vitro formation
Liang F; Kachar B; Ding M; Zhai Z; Wu XR; Sun TT
1999 Jul;65(1):59-69, Differentiation
— id: 6177, year: 1999, vol: 65, page: 59, stat: Journal Article,

Uroplakin and androgen receptor expression in the human fetal female genital tract: Insights into the development of the vagina in normal females and in congenital adrenal hyperplasia
Shapiro, E; Huang, HY; Wu, XR
1999 SEP ;104(3):859-860, Pediatrics
— id: 53840, year: 1999, vol: 104, page: 859, stat: Journal Article,

Uroplakins as markers of urothelial differentiation
Sun TT; Liang FX; Wu XR
1999 ;462:7-18, Advances in experimental medicine & biology
— id: 11902, year: 1999, vol: 462, page: 7, stat: Journal Article,

Urothelium-specific expression of an oncogene in transgenic mice induced the formation of carcinoma in situ and invasive transitional cell carcinoma
Zhang ZT; Pak J; Shapiro E; Sun TT; Wu XR
1999 Jul 15;59(14):3512-3517, Cancer research
— id: 11977, year: 1999, vol: 59, page: 3512, stat: Journal Article,

New concepts on the histological changes in experimental augmentation cystoplasty: Insights into the development of neoplastic transformation at the enterovesical anastomosis
Gitlin, JS; Wu, XR; Ritchey, ML; Shapiro, E
1998 SEP ;102(3):843-843, Pediatrics
— id: 53771, year: 1998, vol: 102, page: 843, stat: Journal Article,

Variants of the FimH adhesion confer distinct patterns of interaction of E-coli with urinary bladder
Hasty, DL; Wu, XR; Sokurenko, E
1998 NOV ;9(11):501A-501A, Molecular biology of the cell
— id: 53653, year: 1998, vol: 9, page: 501A, stat: Journal Article,

Three dimensional analysis of the 16-nm urothelial plaque particle: Luminal surface exposure, preferential head-to-head interaction, and dynamic plaque/hinge formation
Kachar, B; Liang, F; Lins, U; Ding, M; Wu, XR; Stoffler, D; Acbi, U; Sun, TT
1998 NOV ;9(11):78A-78A, Molecular biology of the cell
— id: 53642, year: 1998, vol: 9, page: 78A, stat: Journal Article,

Pathogenic adaptation of Escherichia coli by natural variation of the FimH adhesin
Sokurenko EV; Chesnokova V; Dykhuizen DE; Ofek I; Wu XR; Krogfelt KA; Struve C; Schembri MA; Hasty DL
1998 Jul 21;95(15):8922-8926, Proceedings of the National Academy of Sciences of the United States of America
— id: 7800, year: 1998, vol: 95, page: 8922, stat: Journal Article,

Uroplakin II gene is expressed in transitional cell carcinoma but not in bilharzial bladder squamous cell carcinoma: alternative pathways of bladder epithelial differentiation and tumor formation [published erratum appears in Cancer Res 1998 Jul 1;58(13):2904]
Wu RL; Osman I; Wu XR; Lu ML; Zhang ZF; Liang FX; Hamza R; Scher H; Cordon-Cardo C; Sun TT
1998 Mar 15;58(6):1291-1297, Cancer research
— id: 7863, year: 1998, vol: 58, page: 1291, stat: Journal Article,

Formation of asymmetric unit membrane during urothelial differentiation
Sun TT; Zhao H; Provet J; Aebi U; Wu XR
1996 ;23(1):3-11, Molecular biology reports
— id: 12665, year: 1996, vol: 23, page: 3, stat: Journal Article,

In vitro binding of type 1-fimbriated Escherichia coli to uroplakins Ia and Ib: relation to urinary tract infections
Wu XR; Sun TT; Medina JJ
1996 Sep 3;93(18):9630-9635, Proceedings of the National Academy of Sciences of the United States of America
— id: 8388, year: 1996, vol: 93, page: 9630, stat: Journal Article,

Uroplakins, specific membrane proteins of urothelial umbrella cells, as histological markers of metastatic transitional cell carcinomas
Moll R; Wu XR; Lin JH; Sun TT
1995 Nov;147(5):1383-1397, American journal of pathology
— id: 26914, year: 1995, vol: 147, page: 1383, stat: Journal Article,

Towards the molecular architecture of the asymmetric unit membrane of the mammalian urinary bladder epithelium: a closed "twisted ribbon" structure
Walz T; Haner M; Wu XR; Henn C; Engel A; Sun TT; Aebi U
1995 May 19;248(5):887-900, Journal of molecular biology
— id: 8380, year: 1995, vol: 248, page: 887, stat: Journal Article,

Selective interactions of UPIa and UPIb, two members of the transmembrane 4 superfamily, with distinct single transmembrane-domained proteins in differentiated urothelial cells
Wu XR; Medina JJ; Sun TT
1995 Dec 15;270(50):29752-29759, Journal of biological chemistry
— id: 6976, year: 1995, vol: 270, page: 29752, stat: Journal Article,

Precursor sequence, processing, and urothelium-specific expression of a major 15-kDa protein subunit of asymmetric unit membrane
Lin JH; Wu XR; Kreibich G; Sun TT
1994 Jan 21;269(3):1775-1784, Journal of biological chemistry
— id: 8249, year: 1994, vol: 269, page: 1775, stat: Journal Article,

Rapid communication: PstI, HindIII, and TaqI restriction fragment length polymorphisms in the bovine Uroplakin IB gene
Ryan AM; Womack JE; Lin JH; Yu J; Wu XR; Sun TT
1994 Jul;72(7):1909-1909, Jounral of animal science
— id: 34165, year: 1994, vol: 72, page: 1909, stat: Journal Article,

TaqI and BglII RFLPs for the bovine uroplakin III loci UPK3A and UPK3B
Ryan AM; Womack JE; Wu XR; Sun TT
1994 Feb;25(1):64-64, Animal genetics
— id: 34167, year: 1994, vol: 25, page: 64, stat: Journal Article,

Rapid communication: BamHI and TaqI restriction fragment length polymorphisms in the bovine Uroplakin IA gene
Ryan AM; Womack JE; Yu J; Lin JH; Wu XR; Sun TT
1994 Jul;72(7):1908-1908, Jounral of animal science
— id: 34166, year: 1994, vol: 72, page: 1908, stat: Journal Article,

Mammalian uroplakins. A group of highly conserved urothelial differentiation-related membrane proteins
Wu XR; Lin JH; Walz T; Haner M; Yu J; Aebi U; Sun TT
1994 May 6;269(18):13716-13724, Journal of biological chemistry
— id: 12966, year: 1994, vol: 269, page: 13716, stat: Journal Article,

Uroplakins Ia and Ib, two major differentiation products of bladder epithelium, belong to a family of four transmembrane domain (4TM) proteins
Yu J; Lin JH; Wu XR; Sun TT
1994 Apr;125(1):171-182, Journal of cell biology
— id: 6560, year: 1994, vol: 125, page: 171, stat: Journal Article,

[Uroplakin III, a specific membrane protein of urothelial umbrella cells, as a histological markers for metastatic transitional cell carcinomas]
Moll, R; Laufer, J; Wu, X R; Sun, T T
1993 ;77:260-265, Verhandlungen der Deutschen Gesellschaft fur Pathologie
— id: 132744, year: 1993, vol: 77, page: 260, stat: Journal Article,

Chromosomal localization of uroplakin genes of cattle and mice
Ryan AM; Womack JE; Yu J; Lin JH; Wu XR; Sun TT; Clarke V; D'Eustachio P
1993 Nov;4(11):656-661, Mammalian genome
— id: 17236, year: 1993, vol: 4, page: 656, stat: Journal Article,

Molecular cloning of a 47 kDa tissue-specific and differentiation-dependent urothelial cell surface glycoprotein
Wu XR; Sun TT
1993 Sep;106(Pt 1):31-43, Journal of cell science
— id: 13082, year: 1993, vol: 106, page: 31, stat: Journal Article,

Large scale purification and immunolocalization of bovine uroplakins I, II, and III. Molecular markers of urothelial differentiation
Wu XR; Manabe M; Yu J; Sun TT
1990 Nov 5;265(31):19170-19179, Journal of biological chemistry
— id: 14277, year: 1990, vol: 265, page: 19170, stat: Journal Article,

Uroplakin I: a 27-kD protein associated with the asymmetric unit membrane of mammalian urothelium
Yu J; Manabe M; Wu XR; Xu C; Surya B; Sun TT
1990 Sep;111(3):1207-1216, Journal of cell biology
— id: 26925, year: 1990, vol: 111, page: 1207, stat: Journal Article,