Donald A. Wilson

Biosketch / Results /

Donald Wilson

Professor, Department of Child and Adolescent Psychiatry
Professor, Department of Neuroscience and Physiology


Contact Info

Address
1 Park Avenue
New York, NY 10016

646/754-5159
Donald.Wilson@nyumc.org


Research Summary

My lab and I are interested in how the mammalian brain processes and remembers information. As a model system we focus on rat discrimination and memory for odors. Using electrophysiological, behavioral, neuroanatomical and pharmacological approaches, we explore the neurobiology of memory and the role of experience in sensory system function. The underlying hypothesis of much of our work is that memory plays a critical role in even basic sensory discrimination. In addition, we are interested in how experience and pathology across the life span can influence sensory system function and perception. For example, we are interested in how disruptions of even very simple neural mechanisms during early development can lead to a cascade of long-lasting consequences for brain and behavior, and how the deposition of amyloid proteins in the brain in an animal model of Alzheimer's disease shape sensory coding and perception. An overview of our understanding of odor perception is summarized in the TEDx talk linked above.

Research Keywords

molecular, cellular, & translational neuroscience, systems, cognitive, & computational neuroscience

Neurobehavioral Assessment of Maternal Odor in Developing Rat Pups: Implications for Social Buffering
Al Ain, Syrina; Perry, Rosemarie E; Nunez, Bestina; Kayser, Kassandra; Hochman, Chase; Brehman, Elizabeth; LaComb, Miranda; Wilson, Donald A; Sullivan, Regina M. Neurobehavioral Assessment of Maternal Odor in Developing Rat Pups: Implications for Social Buffering. Social neuroscience. 2017 Feb;12(1):32-49 (2009342)

Apolipoprotein E4 causes early olfactory network abnormalities and short-term olfactory memory impairments
Peng, Katherine Y; Mathews, Paul M; Levy, Efrat; Wilson, Donald A. Apolipoprotein E4 causes early olfactory network abnormalities and short-term olfactory memory impairments. Neuroscience. 2016 Dec 18;343:364-371 (2374382)

Stimulation-induced transient changes in neuronal activity, blood flow and N-acetylaspartate content in rat prefrontal cortex: a chemogenetic fMRS-BOLD study
Baslow, Morris H; Cain, Christopher K; Sears, Robert; Wilson, Donald A; Bachman, Alvin; Gerum, Scott; Guilfoyle, David N. Stimulation-induced transient changes in neuronal activity, blood flow and N-acetylaspartate content in rat prefrontal cortex: a chemogenetic fMRS-BOLD study. NMR in biomedicine. 2016 Dec;29(12):1678-1687 (2273962)

Default mode network deactivation during odor-visual association
Karunanayaka, Prasanna R; Wilson, Donald A; Tobia, Michael J; Martinez, Brittany E; Meadowcroft, Mark D; Eslinger, Paul J; Yang, Qing X. Default mode network deactivation during odor-visual association. Human brain mapping. 2016 Oct 27;:?-? (2288772)

The Olfactory Mosaic: Bringing an Olfactory Network Together for Odor Perception
Courtiol, Emmanuelle; Wilson, Donald A. The Olfactory Mosaic: Bringing an Olfactory Network Together for Odor Perception. Perception. 2016 Sep 28;:?-? (2262742)