Susan L Smith

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Susan L Smith, Ph.D.

Professor; Grad Ad Molecular Onc & Imm Grad Pgm
Department of Pathology (Skirball) and Molecular Pathogenesis

Contact Info

540 First Avenue
Floor 2 Room Lab 9
Skirball Institute
New York, NY 10016-6481


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— Rockefeller University, PostDoctoral Training
— State University of New York at Stony Brook, Graduate Education

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All data from NYU Health Sciences Library Faculty Bibliography — -


Persistent telomere cohesion triggers a prolonged anaphase
Kim, Mi Kyung; Smith, Susan
2014 Jan;25(1):30-40, Molecular biology of the cell
— id: 781822, year: 2014, vol: 25, page: 30, stat: Journal Article,

SA1 binds directly to DNA through its unique AT-hook to promote sister chromatid cohesion at telomeres
Bisht, Kamlesh K; Daniloski, Zharko; Smith, Susan
2013 Aug;126(Pt 15):3493-3503, Journal of cell science
— id: 484052, year: 2013, vol: 126, page: 3493, stat: Journal Article,

TIN2 stability is regulated by the E3 ligase Siah2
Bhanot, Monica; Smith, Susan
2012 Jan;32(2):376-384, Molecular & cellular biology
— id: 157613, year: 2012, vol: 32, page: 376, stat: Journal Article,

GDP-Mannose-4,6-Dehydratase Is a Cytosolic Partner of Tankyrase 1 That Inhibits Its Poly(ADP-Ribose) Polymerase Activity
Bisht, Kamlesh K; Dudognon, Charles; Chang, William G; Sokol, Ethan S; Ramirez, Alejandro; Smith, Susan
2012 Aug;32(15):3044-3053, Molecular & cellular biology
— id: 173024, year: 2012, vol: 32, page: 3044, stat: Journal Article,

A role for sister telomere cohesion in telomere elongation by telomerase
Houghtaling, Benjamin R; Canudas, Silvia; Smith, Susan
2012 Jan 1;11(1):19-25, Cell cycle
— id: 149956, year: 2012, vol: 11, page: 19, stat: Journal Article,

Tankyrase 1 regulates centrosome function by controlling CPAP stability
Kim, Mi Kyung; Dudognon, Charles; Smith, Susan
2012 Aug;13(8):724-732, EMBO reports
— id: 174386, year: 2012, vol: 13, page: 724, stat: Journal Article,

mRNA Decay Factor AUF1 Maintains Normal Aging, Telomere Maintenance, and Suppression of Senescence by Activation of Telomerase Transcription
Pont, Adam R; Sadri, Navid; Hsiao, Susan J; Smith, Susan; Schneider, Robert J
2012 Jul;47(1):5-15, Molecular cell
— id: 173022, year: 2012, vol: 47, page: 5, stat: Journal Article,

Poly(ADP-ribose) polymerase 3 (PARP3), a newcomer in cellular response to DNA damage and mitotic progression
Boehler, Christian; Gauthier, Laurent R; Mortusewicz, Oliver; Biard, Denis S; Saliou, Jean-Michel; Bresson, Anne; Sanglier-Cianferani, Sarah; Smith, Susan; Schreiber, Valerie; Boussin, Francois; Dantzer, Francoise
2011 Feb 15;108(7):2783-2788, Proceedings of the National Academy of Sciences of the United States of America
— id: 134153, year: 2011, vol: 108, page: 2783, stat: Journal Article,

A role for heterochromatin protein 1{gamma} at human telomeres
Canudas, Silvia; Houghtaling, Benjamin R; Bhanot, Monica; Sasa, Ghadir; Savage, Sharon A; Bertuch, Alison A; Smith, Susan
2011 Sep 1;25(17):1807-1819, Genes & development
— id: 137073, year: 2011, vol: 25, page: 1807, stat: Journal Article,

Differential regulation of telomere and centromere cohesion by the Scc3 homologues SA1 and SA2, respectively, in human cells
Canudas, Silvia; Smith, Susan
2009 Oct 19;187(2):165-173, Journal of cell biology
— id: 104723, year: 2009, vol: 187, page: 165, stat: Journal Article,

Sister telomeres rendered dysfunctional by persistent cohesion are fused by NHEJ
Hsiao, Susan J; Smith, Susan
2009 Feb 23;184(4):515-526, Journal of cell biology
— id: 93576, year: 2009, vol: 184, page: 515, stat: Journal Article,

The long and short of it: a new isoform of TIN2 in the nuclear matrix
Smith, Susan
2009 Mar 15;8(6):797-798, Cell cycle
— id: 137817, year: 2009, vol: 8, page: 797, stat: Journal Article,

The SAGA the end
Smith, Susan
2009 Aug 14;35(3):256-258, Molecular cell
— id: 101646, year: 2009, vol: 35, page: 256, stat: Journal Article,

Tankyrase 1 and tankyrase 2 are essential but redundant for mouse embryonic development
Chiang, Y Jeffrey; Hsiao, Susan J; Yver, Dena; Cushman, Samuel W; Tessarollo, Lino; Smith, Susan; Hodes, Richard J
2008 ;3(7):e2639-e2639, PLoS one
— id: 88580, year: 2008, vol: 3, page: e2639, stat: Journal Article,

Tankyrase function at telomeres, spindle poles, and beyond
Hsiao, Susan J; Smith, Susan
2008 Jan;90(1):83-92, Biochimie
— id: 76329, year: 2008, vol: 90, page: 83, stat: Journal Article,

Protein requirements for sister telomere association in human cells
Canudas, Silvia; Houghtaling, Benjamin R; Kim, Ju Youn; Dynek, Jasmin N; Chang, William G; Smith, Susan
2007 Nov 28;26(23):4867-4878, EMBO journal
— id: 75398, year: 2007, vol: 26, page: 4867, stat: Journal Article,

Tankyrase 2 poly(ADP-ribose) polymerase domain-deleted mice exhibit growth defects but have normal telomere length and capping
Hsiao, Susan J; Poitras, Marc F; Cook, Brandoch D; Liu, Yie; Smith, Susan
2006 Mar;26(6):2044-2054, Molecular & cellular biology
— id: 64582, year: 2006, vol: 26, page: 2044, stat: Journal Article,

NuMA is a major acceptor of poly(ADP-ribosyl)ation by tankyrase 1 in mitosis
Chang, William; Dynek, Jasmin N; Smith, Susan
2005 Oct 15;391(2):177-184, Biochemical journal
— id: 58149, year: 2005, vol: 391, page: 177, stat: Journal Article,

Resolution of sister telomere association is required for progression through mitosis
Dynek, Jasmin N; Smith, Susan
2004 Apr 2;304(5667):97-100, Science
— id: 42576, year: 2004, vol: 304, page: 97, stat: Journal Article,

A dynamic molecular link between the telomere length regulator TRF1 and the chromosome end protector TRF2
Houghtaling, Benjamin R; Cuttonaro, Leanora; Chang, William; Smith, Susan
2004 Oct 21;14(18):1621-1631, Current biology. CB
— id: 46295, year: 2004, vol: 14, page: 1621, stat: Journal Article,

Functional subdomain in the ankyrin domain of tankyrase 1 required for poly(ADP-ribosyl)ation of TRF1 and telomere elongation
Seimiya, Hiroyuki; Muramatsu, Yukiko; Smith, Susan; Tsuruo, Takashi
2004 Mar;24(5):1944-1955, Molecular & cellular biology
— id: 137818, year: 2004, vol: 24, page: 1944, stat: Journal Article,

TRF1 is degraded by ubiquitin-mediated proteolysis after release from telomeres
Chang, William; Dynek, Jasmin N; Smith, Susan
2003 Jun 1;17(11):1328-1333, Genes & development
— id: 36833, year: 2003, vol: 17, page: 1328, stat: Journal Article,

Role for the Related Poly(ADP-Ribose) Polymerases Tankyrase 1 and 2 at Human Telomeres
Cook, Brandoch D; Dynek, Jasmin N; Chang, William; Shostak, Grigoriy; Smith, Susan
2002 Jan 1;22(1):332-342, Molecular & cellular biology
— id: 24853, year: 2002, vol: 22, page: 332, stat: Journal Article,

The telomeric poly(ADP-ribose) polymerase, tankyrase 1, contains multiple binding sites for telomeric repeat binding factor 1 (TRF1) and a novel acceptor, 182-kDa tankyrase-binding protein (TAB182)
Seimiya, Hiroyuki; Smith, Susan
2002 Apr 19;277(16):14116-14126, Journal of biological chemistry
— id: 39708, year: 2002, vol: 277, page: 14116, stat: Journal Article,

The world according to PARP
Smith S
2001 Mar;26(3):174-179, Trends in biochemical sciences
— id: 20290, year: 2001, vol: 26, page: 174, stat: Journal Article,

Mammalian meiotic telomeres: protein composition and redistribution in relation to nuclear pores
Scherthan H; Jerratsch M; Li B; Smith S; Hulten M; Lock T; de Lange T
2000 Dec;11(12):4189-4203, Molecular biology of the cell
— id: 20289, year: 2000, vol: 11, page: 4189, stat: Journal Article,

Tankyrase promotes telomere elongation in human cells
Smith S; de Lange T
2000 Oct 19;10(20):1299-1302, Current biology. CB
— id: 20288, year: 2000, vol: 10, page: 1299, stat: Journal Article,

Recombination: a means to an end in human cells
Smith, S
2000 Dec;26(4):388-389, Nature genetics
— id: 137819, year: 2000, vol: 26, page: 388, stat: Journal Article,

Cell cycle dependent localization of the telomeric PARP, tankyrase, to nuclear pore complexes and centrosomes
Smith S; de Lange T
1999 Nov;112(Pt 21):3649-3656, Journal of cell science
— id: 8360, year: 1999, vol: 112, page: 3649, stat: Journal Article,

Chromosomal mapping of the tankyrase gene in human and mouse
Zhu L; Smith S; de Lange T; Seldin MF
1999 Apr 15;57(2):320-321, Genomics
— id: 8359, year: 1999, vol: 57, page: 320, stat: Journal Article,

Tankyrase, a poly(ADP-ribose) polymerase at human telomeres
Smith S; Giriat I; Schmitt A; de Lange T
1998 Nov 20;282(5393):1484-1487, Science
— id: 8358, year: 1998, vol: 282, page: 1484, stat: Journal Article,

TRF1 is a dimer and bends telomeric DNA
Bianchi A; Smith S; Chong L; Elias P; de Lange T
1997 Apr 1;16(7):1785-1794, EMBO journal
— id: 20287, year: 1997, vol: 16, page: 1785, stat: Journal Article,

TRF1, a mammalian telomeric protein
Smith S; de Lange T
1997 Jan;13(1):21-26, Trends in genetics
— id: 20286, year: 1997, vol: 13, page: 21, stat: Journal Article,