Robert J Schneider

Biosketch / Results /

Robert Schneider

Albert B. Sabin Professor of Microbiology and Molecular Pathogenesis, Department of Microbiology;Professor, Department of Radiation Oncology
Microbiology

Contact Info

212/263-6006
Robert.Schneider@nyumc.org

Research Summary

I am an Associate Director of the NYU Cancer Institute, Director of Translational Cancer Research, and Co-director of the Breast Cancer Research Program at NYU School of Medicine. Our research is directed to three major areas: (1) the molecular and genetic understanding of advanced breast cancers and the development of new treatment strategies and therapeutics for advanced breast cancers, focusing particularly on the role of protein synthesis and mTOR kinase regulation; (2) the molecular understanding of gene regulation by ionizing radiation, particularly its ability to regulate protein synthesis and use of this knowledge for development of new cancer treatment strategies; and (3) regulation of the inflammatory response by targeted rapid degradation of inflammatory cytokine mRNAs, and the connection to cancer development and progression.

Research Interests

Breast cancer genetics and molecular biology, Post-transcriptional control of gene expression, role of protein synthesis in cancer development

Equol, an Isoflavone Metabolite, Regulates Cancer Cell Viability and Protein Synthesis Initiation via c-Myc and eIF4G
de la Parra, Columba; Borrero-Garcia, Luis D; Cruz-Collazo, Ailed; Schneider, Robert J; Dharmawardhane, Suranganie
2015-03-16; 0021-9258,Journal of biological chemistry - id: 1495552, year: 2015 Journal Article

eIF4E is a Feed-forward Translational Coactivator of TGFbeta Early Pro-transforming Events in Breast Epithelial Cells
Decarlo, Lindsey; Mestel, Celine; Barcellos-Hoff, Mary-Helen; Schneider, Robert J
2015-05-24; 1098-5549,Molecular & cellular biology - id: 1590752, year: 2015 JOURNAL ARTICLE

Inflammatory breast cancer: Mixed viral infections within carcinoma tissues and the expression of Ki-67 proliferation marker.
Mohamed, Hossam Taha; Hesham, Hadeer; Fattah, Abdel; El-Shinawi, Mohamed; Ibrahim, Sherif Abdelaziz; El-Halawany, Medhat S; El Ghazaly, Hesham; Schneider, Robert; Mohamed, Mona
2015-08-20; 1527-7755,Journal of clinical oncology - id: 1729852, year: 2015

Interleukin-17 enhances immunosuppression by mesenchymal stem cells
Han, X; Yang, Q; Lin, L; Xu, C; Zheng, C; Chen, X; Han, Y; Li, M; Cao, W; Cao, K; Chen, Q; Xu, G; Zhang, Y; Zhang, J; Schneider, R J; Qian, Y; Wang, Y; Brewer, G; Shi, Y
2014-10-13; 1350-9047,Cell death & differentiation - id: 1298722, year: 2014 Journal Article

Dual mTORC1/2 inhibition in a preclinical xenograft tumor model of endometrial cancer
Korets, Sharmilee Bansal; Musa, Fernanda; Curtin, John; Blank, Stephanie V; Schneider, Robert J
2014-02-24; 0090-8258,Gynecologic oncology - id: 810962, year: 2014 Journal Article