Helen E. Scharfman

Helen E. Scharfman, PhD

Professor, Department of Child and Adolescent Psychiatry

Professor, Department of Neuroscience

Professor, Department of Psychiatry

Keywords
hippocampus and parahippocampal areas, their role in normal function and their contribution to neurological disorders and mental illness, neurotrophins (BDNF)and neuronal plasticity , neurogenesis in the dentate gyrus , mechanisms controlling neuronal excitability; seizures; epilepsy, neuronal modulation by reproductive steroids, brain and spinal cord injury; neuroprotection, imaging, molecular, cellular, & translational neuroscience, systems, cognitive, & computational neuroscience

Phone

845-398-5427

Lab Website
Scharfman Lab
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Positions

Professor, Department of Child and Adolescent Psychiatry at NYU Grossman School of Medicine

Professor, Department of Neuroscience at NYU Grossman School of Medicine

Professor, Department of Psychiatry at NYU Grossman School of Medicine

Restoration of sFRP3 preserves the neural stem cell pool and spatial discrimination ability in a mouse model of Alzheimer's disease

Fu, Chia-Hsuan; Park, Jin; Tosi, Umberto; Blanco, Francisco A; Silva-Pérez, Manuel; Muralidharan, Kavitha; You, Jason C; Lee, Minjung; Stephens, Gabriel S; Zhang, Xiaohong; Zheng, Yi; Scharfman, Helen; Tolias, Kimberley F; Chin, Jeannie

Journal of neuroscience. 2025 Dec 03; 45(49):

Sweetens the Pot" for Drug-Resistant Epilepsy-With an After Taste"> Clioquinol "Sweetens the Pot" for Drug-Resistant Epilepsy-With an After Taste

Scharfman, Helen E

Epilepsy currents. 2025 Nov 19; 15357597251387418

Opposing interictal dynamics in Alzheimer's disease and epilepsy

Lisgaras, Christos Panagiotis; Scharfman, Helen E

Progress in neurobiology (1973). 2025 Nov 03; 102844

Getting STAT-isfaction

Scharfman, Helen E

Epilepsy currents. 2025 Jul 17; 15357597251352993

Testosterone and 17β-estradiol regulate hippocampal area CA3 sharp waves in male and female rats

Pearce, Patrice; LaFrancois, John J; Skucas, Vanessa; Friedman, Daniel; Fenton, André A; Dvorak, Dino; MacLusky, Neil J; Scharfman, Helen E

Cell reports. 2025 Jul 08; 44(7):115952

Increased excitability of dentate gyrus mossy cells occurs early in life in the Tg2576 model of Alzheimer's disease

Alcantara-Gonzalez, David; Kennedy, Meghan; Criscuolo, Chiara; Botterill, Justin; Scharfman, Helen E

Alzheimer's research & therapy. 2025 May 15; 17(1):105

Adenosine Makes a Scene

Scharfman, Helen E

Epilepsy currents. 2025 Apr 16; 15357597251323126

Field EPSPs of Dentate Gyrus Granule Cells Studied by Selective Optogenetic Activation of Hilar Mossy Cells in Hippocampal Slices

Bernstein, Hannah L; Lu, Yi-Ling; Botterill, Justin J; Duffy, Áine M; LaFrancois, John J; Scharfman, Helen E

Hippocampus. 2025 Jan; 35(1):e23652

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