Helen E. Scharfman

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Helen Scharfman

Professor, Department of Child and Adolescent Psychiatry;Professor, Department of Neuroscience and Physiology;Professor, Department of Psychiatry
Child and Adolescent Psychiatry

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Research Interests

1. Hippocampus and parahippocampal areas, their role in normal function and their contribution to neurological disorders and mental illness. 2. Neurotrophins (BDNF)and neuronal plasticity 3. Neurogenesis in the dentate gyrus 3. Mechanisms controlling neuronal excitability; seizures; epilepsy. 4. Neuronal modulation by reproductive steroids 5. Brain and spinal cord injury; neuroprotection

Aberrant hippocampal neurogenesis contributes to epilepsy and associated cognitive decline
Cho, Kyung-Ok; Lybrand, Zane R; Ito, Naoki; Brulet, Rebecca; Tafacory, Farrah; Zhang, Ling; Good, Levi; Ure, Kerstin; Kernie, Steven G; Birnbaum, Shari G; Scharfman, Helen E; Eisch, Amelia J; Hsieh, Jenny
2015-03-30; 2041-1723,Nature communications - id: 1514142, year: 2015 Journal Article

Interictal spike frequency varies with ovarian cycle stage in a rat model of epilepsy
D'Amour, James; Magagna-Poveda, Alejandra; Moretto, Jillian; Friedman, Daniel; LaFrancois, John J; Pearce, Patrice; Fenton, Andre A; MacLusky, Neil J; Scharfman, Helen E
2015-04-20; 1090-2430,Experimental neurology - id: 1532672, year: 2015 JOURNAL ARTICLE

Opioid receptor-dependent sex differences in synaptic plasticity in the hippocampal mossy fiber pathway of the adult rat
Harte-Hargrove, Lauren C; Varga-Wesson, Ada; Duffy, Aine M; Milner, Teresa A; Scharfman, Helen E
2015-02-02; 0270-6474,Journal of neuroscience - id: 1447912, year: 2015 Journal Article

Neuroscience. Metabolic control of epilepsy
Scharfman, Helen E
2015-03-23; 0036-8075,Science - id: 1506442, year: 2015 Comment; Journal Article

Observations on hippocampal mossy cells in mink (Neovison vison) with special reference to dendrites ascending to the granular and molecular layers
Sigurd, Jan; Blackstad, B; Osen, Kirsten K; Scharfman, Helen E; Storm-Mathisen, Jon; Blackstad, Theodor W; Leergaard, Trygve B
2015-08-23; 1098-1063,Hippocampus - id: 1732242, year: 2015 JOURNAL ARTICLE