Helen E. Scharfman

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Helen Scharfman

Professor, Department of Child and Adolescent Psychiatry
Professor, Department of Neuroscience and Physiology
Professor, Department of Psychiatry


Contact Info

845/398-5427
Helen.Scharfman@nyumc.org

Research Interests

1. Hippocampus and parahippocampal areas, their role in normal function and their contribution to neurological disorders and mental illness. 2. Neurotrophins (BDNF)and neuronal plasticity 3. Neurogenesis in the dentate gyrus 3. Mechanisms controlling neuronal excitability; seizures; epilepsy. 4. Neuronal modulation by reproductive steroids 5. Brain and spinal cord injury; neuroprotection

Activation of local inhibitory circuits in the dentate gyrus by adult-born neurons
Drew, Liam J; Kheirbek, Mazen A; Luna, Victor M; Denny, Christine A; Cloidt, Megan A; Wu, Melody V; Jain, Swati; Scharfman, Helen E; Hen, Rene. Activation of local inhibitory circuits in the dentate gyrus by adult-born neurons. Hippocampus. 2016 Feb 8;26(6):763-778 (1877832)

Interictal spikes during sleep are an early defect in the Tg2576 mouse model of beta-amyloid neuropathology
Kam, Korey; Duffy, Aine M; Moretto, Jillian; LaFrancois, John J; Scharfman, Helen E. Interictal spikes during sleep are an early defect in the Tg2576 mouse model of beta-amyloid neuropathology. Scientific reports. 2016 Jan 28;6:20119-20119 (1929152)

Expansion of mossy fibers and CA3 apical dendritic length accompanies the fall in dendritic spine density after gonadectomy in male, but not female, rats
Mendell, Ari L; Atwi, Sarah; Bailey, Craig D C; McCloskey, Dan; Scharfman, Helen E; MacLusky, Neil J. Expansion of mossy fibers and CA3 apical dendritic length accompanies the fall in dendritic spine density after gonadectomy in male, but not female, rats. Brain structure & function. 2016 Jun 9;:?-? (2136592)

The enigmatic mossy cell of the dentate gyrus
Scharfman, Helen E. The enigmatic mossy cell of the dentate gyrus. Nature reviews. Neuroscience. 2016 Jul 28;17(9):562-575 (2191602)

Sleep EEG changes in preclinical alzheimer disease: A pilot study
Schutz, S; Varga, A; Kam, K; Ducca, E; Wohlleber, M; Lewis, C; Jean-Louis, G; Ayappa, I; Rapoport, D; Osorio, R; Scharfman, H. Sleep EEG changes in preclinical alzheimer disease: A pilot study [Meeting Abstract]. Neurology. 2016 05 Apr 2016;86(16):- (2096632)