James L Salzer

Biosketch / Results /

James L Salzer, M.D., Ph.D.

Professor; Co-Dir of Center of Excellence for Mult Sclerosis
Departments of Neuroscience and Physiology (Neuro/Phys) and Neurology (Administration)

Contact Info

Address
522 First Avenue
Floor 5 Room 505
Smilow Research Building
New York, NY 10016

212-263-0758
212-263-9170
James.Salzer@nyumc.org


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Education

1980 — Washington University, Medical Education
1981-1984 — Residency Training in Neurology at New York Hospital-Cornell Medical Center, Residency

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Research Summary

Our laboratory is investigating the complex, reciprocal interactions between axons and myelinating glia, i.e. Schwann cells in the peripheral nervous system and oligodendrocytes in the central nervous system. Axons promote the proliferation, survival and differentiation of these glial cells including, most dramatically, their formation of the myelin sheath. Glial cells, in turn, provide trophic factors that promote neuronal survival; they also regulate the organization of myelinated axons into distinct physiologic domains that promote the rapid and efficient propagation of action potentials via saltatory conduction. Elucidation of the juxtacrine signaling between these cells will be critical for an understanding of how myelinated nerves form and may provide important insights into the pathogenesis of demyelinating disorders.

Our current studies are focused on three major areas. First, we are characterizing the role of the neuregulin-1 family of neuronal growth factors, and the downstream signaling pathways they activate, in glial cell genesis, differentiation and response to injury. Second, we are developing strategies to identify neuronal signals that promote myelination - signals that have been elusive to date. Lastly, we are investigating the mechanisms by which axons become organized into distinct longitudinal domain. These domains include the node of Ranvier, which contains high concentrations of sodium channels, the paranodal region, which contains specialized junctions that form between the axon and the terminal loops of the myelin sheath, and the juxtaparanodal region which is enriched in delayed rectifier potassium channels. Recent studies suggest these junctions are comprised of a multiprotein complex of cell adhesion molecules and that they function to delineate the distribution of sodium and potassium channels. We are characterizing other components of these junctions and the interactions responsible for node formation using myelinating cocultures, biochemical methods and genetic engineered murine lines.

Research Interests

Cell-Cell Interactions During Neural Development

Research Keywords

axonal-glial interactions, myelination, neural cell adhesion molecules, node of Ranvier

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All data from NYU Health Sciences Library Faculty Bibliography — -

Contact:
http://hsl.med.nyu.edu/faculty-bibliography-search

Functionally distinct PI 3-kinase pathways regulate myelination in the peripheral nervous system
Heller, Bradley A; Ghidinelli, Monica; Voelkl, Jakob; Einheber, Steven; Smith, Ryan; Grund, Ethan; Morahan, Grant; Chandler, David; Kalaydjieva, Luba; Giancotti, Filippo; King, Rosalind H; Fejes-Toth, Aniko Naray; Fejes-Toth, Gerard; Feltri, Maria Laura; Lang, Florian; Salzer, James L
2014 Mar;204(7):1219-1236, Journal of cell biology
— id: 867262, year: 2014, vol: 204, page: 1219, stat: Journal Article,

The 4.1B cytoskeletal protein regulates the domain organization and sheath thickness of myelinated axons
Einheber, Steven; Meng, Xiaosong; Rubin, Marina; Lam, Isabel; Mohandas, Narla; An, Xiuli; Shrager, Peter; Kissil, Joseph; Maurel, Patrice; Salzer, James L
2013 Feb;61(2):240-253, Glia
— id: 209572, year: 2013, vol: 61, page: 240, stat: Journal Article,

Mutation of SIMPLE in Charcot-Marie-Tooth 1C alters production of exosomes
Zhu, Hong; Guariglia, Sara; Yu, Raymond Y L; Li, Wenjing; Brancho, Deborah; Peinado, Hector; Lyden, David; Salzer, James; Bennett, Craig; Chow, Chi-Wing
2013 Jun;24(11):1619-37, S1, Molecular biology of the cell
— id: 449862, year: 2013, vol: 24, page: 1619, stat: Journal Article,

Identification of the Cysteine Residue Responsible for Disulfide Linkage of Na+ Channel alpha and beta2 Subunits
Chen, Chunling; Calhoun, Jeffrey D; Zhang, Yanqing; Lopez-Santiago, Luis; Zhou, Ningna; Davis, Tigwa H; Salzer, James L; Isom, Lori L
2012 Nov;287(46):39061-39069, Journal of biological chemistry
— id: 185522, year: 2012, vol: 287, page: 39061, stat: Journal Article,

Axonal regulation of Schwann cell ensheathment and myelination
Salzer, James L
2012 Dec;17 Suppl 3:14-19, Journal of the peripheral nervous system
— id: 211152, year: 2012, vol: 17 Suppl 3, page: 14, stat: Journal Article,

Assembly and maintenance of nodes of ranvier rely on distinct sources of proteins and targeting mechanisms
Zhang, Yanqing; Bekku, Yoko; Dzhashiashvili, Yulia; Armenti, Stephen; Meng, Xiaosong; Sasaki, Yo; Milbrandt, Jeffrey; Salzer, James L
2012 Jan 12;73(1):92-107, Neuron
— id: 149962, year: 2012, vol: 73, page: 92, stat: Journal Article,

MMP2-9 Cleavage of Dystroglycan Alters the Size and Molecular Composition of Schwann Cell Domains
Court, Felipe A; Zambroni, Desiree; Pavoni, Ernesto; Colombelli, Cristina; Baragli, Chiara; Figlia, Gianluca; Sorokin, Lydia; Ching, William; Salzer, James L; Wrabetz, Lawrence; Feltri, M Laura
2011 Aug 24;31(34):12208-12217, Journal of neuroscience
— id: 136952, year: 2011, vol: 31, page: 12208, stat: Journal Article,

TACE (ADAM17) inhibits Schwann cell myelination
La Marca, Rosa; Cerri, Federica; Horiuchi, Keisuke; Bachi, Angela; Feltri, M Laura; Wrabetz, Lawrence; Blobel, Carl P; Quattrini, Angelo; Salzer, James L; Taveggia, Carla
2011 Jul;14(7):857-865, Nature neuroscience
— id: 948102, year: 2011, vol: 14, page: 857, stat: Journal Article,

MLCK regulates Schwann cell cytoskeletal organization, differentiation and myelination
Leitman, Ellen M; Tewari, Ambika; Horn, Meryl; Urbanski, Mateusz; Damanakis, Evangelos; Einheber, Steven; Salzer, James L; de Lanerolle, Primal; Melendez-Vasquez, Carmen V
2011 Nov;124(Pt 22):3784-3796, Journal of cell science
— id: 939072, year: 2011, vol: 124, page: 3784, stat: Journal Article,

Electron tomography of paranodal septate-like junctions and the associated axonal and glial cytoskeletons in the central nervous system
Nans, Andrea; Einheber, Steven; Salzer, James L; Stokes, David L
2011 Mar;89(3):310-319, Journal of neuroscience research
— id: 121328, year: 2011, vol: 89, page: 310, stat: Journal Article,

David Colman: A Tribute
Salzer J.; Dunn R.; Brophy P.
2011 ;71(2):206-208, Neuron
— id: 135594, year: 2011, vol: 71, page: 206, stat: Journal Article,

Role of secretases in myelination
LaMarca R.; Cerri F.; Horiuchi K.; Bachi A.; Feltri M.L.; Wrabetz L.; Quattrini A.; Blobel C.P.; Salzer J.L.; Taveggia C.
2010 ;15:16-16, Journal of the peripheral nervous system
— id: 135278, year: 2010, vol: 15, page: 16, stat: Journal Article,

Soluble neuregulin-1 has bifunctional, concentration-dependent effects on Schwann cell myelination
Syed, Neeraja; Reddy, Kavya; Yang, David P; Taveggia, Carla; Salzer, James L; Maurel, Patrice; Kim, Haesun A
2010 Apr;30(17):6122-6131, Journal of neuroscience
— id: 948092, year: 2010, vol: 30, page: 6122, stat: Journal Article,

SECRETASES AND NEUREGULIN IN MYELINATION
La Marca, R; Bachi, A; Quattrini, A; Salzer, JL; Taveggia, C
2009 JUL ;14(9):84-85, Journal of the peripheral nervous system
— id: 102291, year: 2009, vol: 14, page: 84, stat: Journal Article,

AXON-SCHWANN CELL INTERACTIONS THAT PROMOTE MYELINATION
Salzer, JL
2009 JUL ;14(9):3-4, Journal of the peripheral nervous system
— id: 102288, year: 2009, vol: 14, page: 3, stat: Journal Article,

Introduction. Schwann cell biology
Jessen, Kristjan R; Mirsky, Rhona; Salzer, James
2008 Nov 1;56(14):1479-1480, Glia
— id: 135306, year: 2008, vol: 56, page: 1479, stat: Journal Article,

The nectin-like proteins are internodal adhesion molecules required for myelination
Maurel, P; Einheber, S; Thaker, P; Lam, I; Salzer, JL
2008 MAR ;104(1):84-85, Journal of neurochemistry
— id: 75949, year: 2008, vol: 104, page: 84, stat: Journal Article,

Switching myelination on and off
Salzer, James L
2008 May 19;181(4):575-577, Journal of cell biology
— id: 79152, year: 2008, vol: 181, page: 575, stat: Journal Article,

Molecular domains of myelinated axons in the peripheral nervous system
Salzer, James L; Brophy, Peter J; Peles, Elior
2008 Nov 1;56(14):1532-1540, Glia
— id: 93561, year: 2008, vol: 56, page: 1532, stat: Journal Article,

Type III neuregulin-1 promotes oligodendrocyte myelination
Taveggia, Carla; Thaker, Pratik; Petrylak, Ashley; Caporaso, Gregg L; Toews, Arrel; Falls, Douglas L; Einheber, Steven; Salzer, James L
2008 Feb;56(3):284-293, Glia
— id: 76859, year: 2008, vol: 56, page: 284, stat: Journal Article,

Myosin II has distinct functions in PNS and CNS myelin sheath formation
Wang, Haibo; Tewari, Ambika; Einheber, Steven; Salzer, James L; Melendez-Vasquez, Carmen V
2008 Sep 22;182(6):1171-1184, Journal of cell biology
— id: 94628, year: 2008, vol: 182, page: 1171, stat: Journal Article,

Nodes of Ranvier and axon initial segments are ankyrin G-dependent domains that assemble by distinct mechanisms
Dzhashiashvili, Yulia; Zhang, Yanqing; Galinska, Jolanta; Lam, Isabel; Grumet, Martin; Salzer, James L
2007 Jun 4;177(5):857-870, Journal of cell biology
— id: 73381, year: 2007, vol: 177, page: 857, stat: Journal Article,

The Nectin-like proteins form an internodal complex with 4.1B required for PNS myelination
Maurel, P; Einheber, S; Rubin, M; Thaker, P; Kissil, J; Salzer, JL
2007 DEC ;2(6):S30-S30, Neuron glia biology
— id: 87173, year: 2007, vol: 2, page: S30, stat: Journal Article,

The Nectin-like proteins are internodal adhesion molecules required for myelination
Maurel, P; Einheber, S; Thacker, P; Rubin, MB; Salzer, JL
2007 DEC ;2(6):S131-S132, Neuron glia biology
— id: 87175, year: 2007, vol: 2, page: S131, stat: Journal Article,

Nectin-like proteins mediate axon Schwann cell interactions along the internode and are essential for myelination
Maurel, Patrice; Einheber, Steven; Galinska, Jolanta; Thaker, Pratik; Lam, Isabel; Rubin, Marina B; Scherer, Steven S; Murakami, Yoshinuri; Gutmann, David H; Salzer, James L
2007 Aug 27;178(5):861-874, Journal of cell biology
— id: 75370, year: 2007, vol: 178, page: 861, stat: Journal Article,

Type III Neuregulin-1 promotes oligodendrocyte myelination
Taveggia, C; Thaker, P; Caporas, GL; Toews, A; Einheber, S; Salzer, JL
2007 DEC ;2(6):S26-S27, Neuron glia biology
— id: 87172, year: 2007, vol: 2, page: S26, stat: Journal Article,

PARsing the events of myelination
Taveggia, Carla; Salzer, James L
2007 Jan;10(1):17-18, Nature neuroscience
— id: 69485, year: 2007, vol: 10, page: 17, stat: Journal Article,

Interleukin-11 potentiates oligodendrocyte survival and maturation, and myelin formation
Zhang, YT; Taveggia, C; Melendez-Vasquez, CV; Einheber, S; Salzer, JL; Raine, CS; Brosnan, CF; John, G
2007 DEC ;2(6):S110-S110, Neuron glia biology
— id: 87174, year: 2007, vol: 2, page: S110, stat: Journal Article,

Disrupted Axo-Glial Junctions Result in Accumulation of Abnormal Mitochondria at Nodes of Ranvier
Einheber S; Bhat MA; Salzer JL
2006 Aug;2(3):165-174, Neuron glia biology
— id: 94629, year: 2006, vol: 2, page: 165, stat: Journal Article,

Expression of neurotrimin in the normal and injured adult human spinal cord
Grijalva, I; Li, X; Marcillo, A; Salzer, JL; Levi, AD
2006 MAY ;44(5):280-286, Spinal cord
— id: 64174, year: 2006, vol: 44, page: 280, stat: Journal Article,

Neurofascin interactions play a critical role in clustering sodium channels, ankyrin(G) and betaIV spectrin at peripheral nodes of Ranvier
Koticha, Darshan; Maurel, Patrice; Zanazzi, George; Kane-Goldsmith, Noriko; Basak, Sayantani; Babiarz, Joanne; Salzer, James; Grumet, Martin
2006 May 1;293(1):1-12, Developmental biology (Orlando)
— id: 63125, year: 2006, vol: 293, page: 1, stat: Journal Article,

Latent TGF-{beta}1-transduced CD4+ T cells suppress the progression of allergic encephalomyelitis
Murano, Mitsuyuki; Xiong, Xiaozhong; Murano, Naoko; Salzer, James L; Lafaille, Juan J; Tsiagbe, Vincent K
2006 Jan;79(1):140-146, Journal of leukocyte biology
— id: 61318, year: 2006, vol: 79, page: 140, stat: Journal Article,

Axonal regulation of myelination by neuregulin 1
Nave, Klaus-Armin; Salzer, James L
2006 Oct;16(5):492-500, Current opinion in neurobiology
— id: 68993, year: 2006, vol: 16, page: 492, stat: Journal Article,

Interleukin-11 potentiates oligodendrocyte survival and maturation, and myelin formation
Zhang, Yueting; Taveggia, Carla; Melendez-Vasquez, Carmen; Einheber, Steven; Raine, Cedric S; Salzer, James L; Brosnan, Celia F; John, Gareth R
2006 Nov 22;26(47):12174-12185, Journal of neuroscience
— id: 69435, year: 2006, vol: 26, page: 12174, stat: Journal Article,

Differential expression of proteoglycans at central and peripheral nodes of Ranvier
Melendez-Vasquez, Carmen; Carey, David J; Zanazzi, George; Reizes, Ofer; Maurel, Patrice; Salzer, James L
2005 Dec;52(4):301-308, Glia
— id: 61319, year: 2005, vol: 52, page: 301, stat: Journal Article,

Neuregulin-1 type III determines the ensheathment fate of axons
Taveggia, Carla; Zanazzi, George; Petrylak, Ashley; Yano, Hiroko; Rosenbluth, Jack; Einheber, Steven; Xu, Xiaorong; Esper, Raymond M; Loeb, Jeffrey A; Shrager, Peter; Chao, Moses V; Falls, Douglas L; Role, Lorna; Salzer, James L
2005 Sep 1;47(5):681-694, Neuron
— id: 58738, year: 2005, vol: 47, page: 681, stat: Journal Article,

Rho kinase regulates schwann cell myelination and formation of associated axonal domains
Melendez-Vasquez, Carmen V; Einheber, Steven; Salzer, James L
2004 Apr 21;24(16):3953-3963, Journal of neuroscience
— id: 42681, year: 2004, vol: 24, page: 3953, stat: Journal Article,

Caspr regulates the processing of contactin and inhibits its binding to neurofascin
Gollan, Leora; Salomon, Daniela; Salzer, James L; Peles, Elior
2003 Dec 22;163(6):1213-1218, Journal of cell biology
— id: 44993, year: 2003, vol: 163, page: 1213, stat: Journal Article,

Paranodal interactions regulate expression of sodium channel subtypes and provide a diffusion barrier for the node of Ranvier
Rios, Jose C; Rubin, Marina; St Martin, Mary; Downey, Ryan T; Einheber, Steven; Rosenbluth, Jack; Levinson, S Rock; Bhat, Manzoor; Salzer, James L
2003 Aug 6;23(18):7001-7011, Journal of neuroscience
— id: 39114, year: 2003, vol: 23, page: 7001, stat: Journal Article,

Polarized domains of myelinated axons
Salzer, James L
2003 Oct 9;40(2):297-318, Neuron
— id: 39032, year: 2003, vol: 40, page: 297, stat: Journal Article,

Complementary expression and heterophilic interactions between igLON family members neurotrimin and LAMP
Gil, Orlando D; Zhang, Li; Chen, Suzanne; Ren, Y Q; Pimenta, Aurea; Zanazzi, George; Hillman, Dean; Levitt, Pat; Salzer, James L
2002 Jun 5;51(3):190-204, Journal of neurobiology
— id: 27403, year: 2002, vol: 51, page: 190, stat: Journal Article,

Neurobiology. A glial spin on neurotrophins
Hempstead, Barbara L; Salzer, James L
2002 Nov 8;298(5596):1184-1186, Science
— id: 33832, year: 2002, vol: 298, page: 1184, stat: Journal Article,

Contact-Dependent Demyelination by Mycobacterium leprae in the Absence of Immune Cells
Rambukkana, Anura; Zanazzi, George; Tapinos, Nikos; Salzer, James L
2002 May 3;296(5569):927-931, Science
— id: 27404, year: 2002, vol: 296, page: 927, stat: Journal Article,

Nodes of Ranvier come of age
Salzer, James L
2002 Jan;25(1):2-5, Trends in neurosciences
— id: 27405, year: 2002, vol: 25, page: 2, stat: Journal Article,

Axon-glia interactions and the domain organization of myelinated axons requires neurexin IV/Caspr/Paranodin
Bhat MA; Rios JC; Lu Y; Garcia-Fresco GP; Ching W; St Martin M; Li J; Einheber S; Chesler M; Rosenbluth J; Salzer JL; Bellen HJ
2001 May;30(2):369-383, Neuron
— id: 27407, year: 2001, vol: 30, page: 369, stat: Journal Article,

Neurotrimin expression during cerebellar development suggests roles in axon fasciculation and synaptogenesis
Chen S; Gil O; Ren YQ; Zanazzi G; Salzer JL; Hillman DE
2001 Nov;30(11):927-937, Journal of neurocytology
— id: 33543, year: 2001, vol: 30, page: 927, stat: Journal Article,

Nr-CAM and neurofascin interactions regulate ankyrin G and sodium channel clustering at the node of Ranvier
Lustig M; Zanazzi G; Sakurai T; Blanco C; Levinson SR; Lambert S; Grumet M; Salzer JL
2001 Nov 27;11(23):1864-1869, Current biology. CB
— id: 27406, year: 2001, vol: 11, page: 1864, stat: Journal Article,

Nodes of Ranvier form in association with ezrin-radixin-moesin (ERM)-positive Schwann cell processes
Melendez-Vasquez CV; Rios JC; Zanazzi G; Lambert S; Bretscher A; Salzer JL
2001 Jan 30;98(3):1235-1240, Proceedings of the National Academy of Sciences of the United States of America
— id: 26791, year: 2001, vol: 98, page: 1235, stat: Journal Article,

Axon-Schwann cell interactions during peripheral nerve degeneration and regeneration
Scherer SS; Salzer JL
Glial cell development : basic principles and clinical relevance Oxford ; New York : Oxford University Press, 2001,
— id: 3531, year: 2001, vol: , page: 165, stat: Chapter,

Glial growth factor/neuregulin inhibits Schwann cell myelination and induces demyelination
Zanazzi G; Einheber S; Westreich R; Hannocks MJ; Bedell-Hogan D; Marchionni MA; Salzer JL
2001 Mar 19;152(6):1289-1299, Journal of cell biology
— id: 21230, year: 2001, vol: 152, page: 1289, stat: Journal Article,

A glial investment of axons defrayed
Einheber S; Salzer JL
2000 Dec;28(3):627-628, Neuron
— id: 33544, year: 2000, vol: 28, page: 627, stat: Journal Article,

Axonal regulation of Schwann cell proliferation and survival and the initial events of myelination requires PI 3-kinase activity
Maurel P; Salzer JL
2000 Jun 15;20(12):4635-4645, Journal of neuroscience
— id: 11654, year: 2000, vol: 20, page: 4635, stat: Journal Article,

Role of the cell wall phenolic glycolipid-1 in the peripheral nerve predilection of Mycobacterium leprae
Ng V; Zanazzi G; Timpl R; Talts JF; Salzer JL; Brennan PJ; Rambukkana A
2000 Oct 27;103(3):511-524, Cell
— id: 33546, year: 2000, vol: 103, page: 511, stat: Journal Article,

Molecular domains of myelinated axons
Peles E; Salzer JL
2000 Oct;10(5):558-565, Current opinion in neurobiology
— id: 33545, year: 2000, vol: 10, page: 558, stat: Journal Article,

Contactin-associated protein (Caspr) and contactin form a complex that is targeted to the paranodal junctions during myelination
Rios JC; Melendez-Vasquez CV; Einheber S; Lustig M; Grumet M; Hemperly J; Peles E; Salzer JL
2000 Nov 15;20(22):8354-8364, Journal of neuroscience
— id: 33547, year: 2000, vol: 20, page: 8354, stat: Journal Article,

Cell cycle control of Schwann cell proliferation: role of cyclin-dependent kinase-2
Tikoo R; Zanazzi G; Shiffman D; Salzer J; Chao MV
2000 Jun 15;20(12):4627-4634, Journal of neuroscience
— id: 14640, year: 2000, vol: 20, page: 4627, stat: Journal Article,

GGF/neuregulin induces a phenotypic reversion of oligodendrocytes
Canoll PD; Kraemer R; Teng KK; Marchionni MA; Salzer JL
1999 Feb;13(2):79-94, Molecular & cellular neurosciences
— id: 6079, year: 1999, vol: 13, page: 79, stat: Journal Article,

Clustering of neuronal sodium channels requires contact with myelinating Schwann cells
Ching W; Zanazzi G; Levinson SR; Salzer JL
1999 Apr-May;28(4-5):295-301, Journal of neurocytology
— id: 11784, year: 1999, vol: 28, page: 295, stat: Journal Article,

Expression of caveolin-1 and -2 in neurons
Galbiati F; Volonte D; Gil O; Zanazzi G; Salzer JL; Sargiacomo M; Scherer PE; Engelman JA; Schlegel A; Parenti M; Okamoto T; Lisanti MP
1999 ;72:S87-S87, Journal of neurochemistry
— id: 8135, year: 1999, vol: 72, page: S87, stat: Journal Article,

Caspr2, a new member of the neurexin superfamily, is localized at the juxtaparanodes of myelinated axons and associates with K+ channels
Poliak S; Gollan L; Martinez R; Custer A; Einheber S; Salzer JL; Trimmer JS; Shrager P; Peles E
1999 Dec;24(4):1037-1047, Neuron
— id: 27874, year: 1999, vol: 24, page: 1037, stat: Journal Article,

Creating barriers: a new role for Schwann cells and Desert hedgehog
Salzer JL
1999 Aug;23(4):627-629, Neuron
— id: 6199, year: 1999, vol: 23, page: 627, stat: Journal Article,

Spatial and temporal distribution of neurotrimin during cerebellar development
Chen, S.; Gil, O.; Ren, Y. Q.; Salzer, J.; Hillman, D.
1998 ;24(1-2):287-287, Abstracts (Society for Neuroscience)
— id: 92253, year: 1998, vol: 24, page: 287, stat: Journal Article,

Neurotrimin mediates bifunctional effects on neurite outgrowth via homophilic and heterophilic interactions
Gil OD; Zanazzi G; Struyk AF; Salzer JL
1998 Nov 15;18(22):9312-9325, Journal of neuroscience
— id: 7335, year: 1998, vol: 18, page: 9312, stat: Journal Article,

A monoclonal antibody specific for the IgCAM neurotrimin stains sensorimotor and olfactory projections in the rat CNS
Gil, O. D.; Chen, S.; Ren, Y. Q.; Pimenta, A.; Hillman, D.; Levitt, P.; Salzer, J.
1998 ;24(1-2):289-289, Abstracts (Society for Neuroscience)
— id: 92252, year: 1998, vol: 24, page: 289, stat: Journal Article,

Role of alpha-dystroglycan as a Schwann cell receptor for Mycobacterium leprae [see comments]
Rambukkana A; Yamada H; Zanazzi G; Mathus T; Salzer JL; Yurchenco PD; Campbell KP; Fischetti VA
1998 Dec 11;282(5396):2076-2079, Science
— id: 7750, year: 1998, vol: 282, page: 2076, stat: Journal Article,

Ran-2, a glial lineage marker, is a GPI-anchored form of ceruloplasmin
Salzer JL; Lovejoy L; Linder MC; Rosen C
1998 Oct 15;54(2):147-157, Journal of neuroscience research
— id: 7440, year: 1998, vol: 54, page: 147, stat: Journal Article,

Myelin-associated glycoprotein in myelin and expressed by Schwann cells inhibits axonal regeneration and branching
Shen YJ; DeBellard ME; Salzer JL; Roder J; Filbin MT
1998 Sep;12(1-2):79-91, Molecular & cellular neurosciences
— id: 7790, year: 1998, vol: 12, page: 79, stat: Journal Article,

The axonal membrane protein Caspr, a homologue of neurexin IV, is a component of the septate-like paranodal junctions that assemble during myelination
Einheber S; Zanazzi G; Ching W; Scherer S; Milner TA; Peles E; Salzer JL
1997 Dec 15;139(6):1495-1506, Journal of cell biology
— id: 7325, year: 1997, vol: 139, page: 1495, stat: Journal Article,

Neural targeting of Mycobacterium leprae mediated by the G domain of the laminin-alpha2 chain
Rambukkana A; Salzer JL; Yurchenco PD; Tuomanen EI
1997 Mar 21;88(6):811-821, Cell
— id: 18859, year: 1997, vol: 88, page: 811, stat: Journal Article,

Clustering sodium channels at the node of Ranvier: close encounters of the axon-glia kind
Salzer JL
1997 Jun;18(6):843-846, Neuron
— id: 7255, year: 1997, vol: 18, page: 843, stat: Journal Article,

GGF/neuregulin is a neuronal signal that promotes the proliferation and survival and inhibits the differentiation of oligodendrocyte progenitors
Canoll PD; Musacchio JM; Hardy R; Reynolds R; Marchionni MA; Salzer JL
1996 Aug;17(2):229-243, Neuron
— id: 12572, year: 1996, vol: 17, page: 229, stat: Journal Article,

Role of GPI anchored proteins in neural cell adhesion
Struyk AF; Rosen C; Salzer JL
1996 ;16:?-?, Advances in molecular & cell biology
— id: 55828, year: 1996, vol: 16, page: ?, stat: Journal Article,

Transforming growth factor-beta 1 regulates axon/Schwann cell interactions
Einheber S; Hannocks MJ; Metz CN; Rifkin DB; Salzer JL
1995 Apr;129(2):443-458, Journal of cell biology
— id: 7896, year: 1995, vol: 129, page: 443, stat: Journal Article,

POTENTIAL ROLE OF INTEGRINS IN MYELINATION
EINHEBER, S; MILNER, T; GIANCOTTI, F; SALZER, J
1995 AUG ;65(4):S69-S69, Journal of neurochemistry
— id: 86753, year: 1995, vol: 65, page: S69, stat: Journal Article,

Mechanisms of adhesion between axons and glial cells
Salzer JL
The axon : structure, function, and pathophysiology New York : Oxford University Press, 1995,
— id: 3524, year: 1995, vol: , page: 164, stat: Chapter,

Cloning of neurotrimin defines a new subfamily of differentially expressed neural cell adhesion molecules
Struyk AF; Canoll PD; Wolfgang MJ; Rosen CL; D'Eustachio P; Salzer JL
1995 Mar;15(3 Pt 2):2141-2156, Journal of neuroscience
— id: 6757, year: 1995, vol: 15, page: 2141, stat: Journal Article,

Axonal regulation of Schwann cell integrin expression suggests a role for alpha 6 beta 4 in myelination
Einheber S; Milner TA; Giancotti F; Salzer JL
1993 Dec;123(5):1223-1236, Journal of cell biology
— id: 6362, year: 1993, vol: 123, page: 1223, stat: Journal Article,

Expression of unique sets of GPI-linked proteins by different primary neurons in vitro
Rosen CL; Lisanti MP; Salzer JL
1992 May;117(3):617-627, Journal of cell biology
— id: 13624, year: 1992, vol: 117, page: 617, stat: Journal Article,

Expression of recombinant myelin-associated glycoprotein in primary Schwann cells promotes the initial investment of axons by myelinating Schwann cells
Owens GC; Boyd CJ; Bunge RP; Salzer JL
1990 Sep;111(3):1171-1182, Journal of cell biology
— id: 33554, year: 1990, vol: 111, page: 1171, stat: Journal Article,

The myelin-associated glycoproteins: membrane disposition, evidence of a novel disulfide linkage between immunoglobulin-like domains, and posttranslational palmitylation
Pedraza L; Owens GC; Green LA; Salzer JL
1990 Dec;111(6 Pt 1):2651-2661, Journal of cell biology
— id: 14274, year: 1990, vol: 111, page: 2651, stat: Journal Article,

Structure and function of the myelin-associated glycoproteins
Salzer JL; Pedraza L; Brown M; Struyk A; Afar D; Bell J
1990 ;605(3):302-312, Annals of the New York Academy of Sciences
— id: 33555, year: 1990, vol: 605, page: 302, stat: Journal Article,

Mechanisms of cell adhesion in the nervous system: role of the immunoglobulin gene superfamily
Salzer JL; Colman DR
1989 ;11(6):377-390, Developmental neuroscience
— id: 10785, year: 1989, vol: 11, page: 377, stat: Journal Article,

Chromosomal location of the mouse gene that encodes the myelin-associated glycoproteins
D'Eustachio P; Colman DR; Salzer JL
1988 Feb;50(2):589-593, Journal of neurochemistry
— id: 11203, year: 1988, vol: 50, page: 589, stat: Journal Article,

The amino acid sequences of the myelin-associated glycoproteins: homology to the immunoglobulin gene superfamily
Salzer JL; Holmes WP; Colman DR
1987 Apr;104(4):957-965, Journal of cell biology
— id: 33556, year: 1987, vol: 104, page: 957, stat: Journal Article,

Axolemma-enriched fractions isolated from PNS and CNS are mitogenic for cultured Schwann cells
DeVries GH; Salzer JL; Bunge RP
1982 Feb;255(2):295-299, Brain research
— id: 33557, year: 1982, vol: 255, page: 295, stat: Journal Article,

Studies of Schwann cell proliferation. I. An analysis in tissue culture of proliferation during development, Wallerian degeneration, and direct injury
Salzer JL; Bunge RP
1980 Mar;84(3):739-752, Journal of cell biology
— id: 33559, year: 1980, vol: 84, page: 739, stat: Journal Article,

Studies of Schwann cell proliferation. III. Evidence for the surface localization of the neurite mitogen
Salzer JL; Bunge RP; Glaser L
1980 Mar;84(3):767-778, Journal of cell biology
— id: 33560, year: 1980, vol: 84, page: 767, stat: Journal Article,

Studies of Schwann cell proliferation. II. Characterization of the stimulation and specificity of the response to a neurite membrane fraction
Salzer JL; Williams AK; Glaser L; Bunge RP
1980 Mar;84(3):753-766, Journal of cell biology
— id: 33558, year: 1980, vol: 84, page: 753, stat: Journal Article,