Ravinder R Regatte

Biosketch / Results /

Ravinder Regatte

Professor, Department of Radiology
Professor, Department of Orthopaedic Surgery


Contact Info

Address
660 First Avenue
New York, NY 10016

212-263-4857
Ravinder.Regatte@nyumc.org

Research Summary

Quantitative Multinuclear Musculoskeletal Imaging Group (QMMIG) is a multidisciplinary research group within the Center for Biomedical Imaging (CBI), Department of Radiology, NYU Langone Medical Center, New York. This group specifically focuses on the development of novel multinuclear imaging techniques for cartilage (osteoarthritis), trabecular bone (osteoporosis) and skeletal muscle (diabetes). This group is led by Drs. Ravinder Regatte, Ph.D. (Director) and Gregory Chang, MD (Clinical Director) to establish not only an excellent resource for other musculoskeletal imaging investigators but also for the rapid clinical translation of new state-of-the-art methodologies into the routine clinical environment. This goal will be accomplished with the help of excellent resources already available at CBI (state-of-the-art high and ultra high field magnets, RF engineering-core, pulse sequence-core, image reconstruction and post-processing core etc) and multi-departmental and multi-institutional collaborations between basic scientists and clinical researchers from around the world. We are also committed to provide excellent education and training opportunities for post-doctoral fellows, research scientists, clinical fellows, graduate students, radiology residents, and medical students who are interested in multinuclear musculoskeletal imaging methodologies. Research Goals & Directions The primary goal of the Quantitative Multinuclear Musculoskeletal Imaging Group (QMMIG) is to develop novel, quantitative, non-invasive, multinuclear (1H, 23Na and 31P) biomedical imaging technologies for early structural, biochemical, and functional assessment of various musculoskeletal disorders using high and ultra high field MRI systems. Specifically, these new technologies will focus on the development of quantitative imaging methods, new radio-frequency pulse sequences, image post-processing and visualization tools to interrogate the functional integrity of musculoskeletal tissues and the underlying biophysical mechanisms of various clinical diseases such as osteoarthritis, osteoporosis, and diabetes. QMMIG also focuses on the rapid clinical translation of new state-of-the-art methodologies into the routine clinical environment. These methodological developments and clinical translations are driven by multi-departmental and multi-institutional collaborations between basic scientists and clinical researchers from around the world. Our research projects are currently supported by multiple National Institutes of Health (NIH) grants, Bi-national Science Foundation (BSF), Radiological Society of North America (RSNA), Bayer Corporation, and intramural NYULMC Musculoskeletal Center of Excellence seed grants.

Research Keywords

imaging

Serum Urate Levels Predict Joint Space Narrowing in Non-gout Patients with Medial Knee Osteoarthritis
Krasnokutsky, Svetlana; Oshinsky, Charles; Attur, Mukundan; Ma, Sisi; Zhou, Hua; Zheng, Fangfei; Chen, Meng; Patel, Jyoti; Samuels, Jonathan; Pike, Virginia C; Regatte, Ravinder; Bencardino, Jenny; Rybak, Leon; Abramson, Steven; Pillinger, Michael H. Serum Urate Levels Predict Joint Space Narrowing in Non-gout Patients with Medial Knee Osteoarthritis. Arthritis & rheumatology. 2017 Feb 19;:?-? (2460142)

MRI assessment of bone structure and microarchitecture
Chang, Gregory; Boone, Sean; Martel, Dimitri; Rajapakse, Chamith S; Hallyburton, Robert S; Valko, Mitch; Honig, Stephen; Regatte, Ravinder R. MRI assessment of bone structure and microarchitecture. Journal of magnetic resonance imaging. 2017 Feb 6;:?-? (2437312)

A low-cost Mr compatible ergometer to assess post-exercise phosphocreatine recovery kinetics
Naimon, Niels D; Walczyk, Jerzy; Babb, James S; Khegai, Oleksandr; Che, Xuejiao; Alon, Leeor; Regatte, Ravinder R; Brown, Ryan; Parasoglou, Prodromos. A low-cost Mr compatible ergometer to assess post-exercise phosphocreatine recovery kinetics. MAGMA (European Society for Magnetic Resonance in Medicine & Biology). 2017 Jan 4;:?-? (2386752)

Juvenile Particulate Osteochondral Allograft for Treatment of Osteochondral Lesions of the Talus: Detection of Altered Repair Tissue Biochemical Composition Using 7 Tesla MRI and T2 Mapping
Vira, Shaleen; Ramme, Austin J; Chapman, Cary; Xia, Ding; Regatte, Ravinder R; Chang, Gregory. Juvenile Particulate Osteochondral Allograft for Treatment of Osteochondral Lesions of the Talus: Detection of Altered Repair Tissue Biochemical Composition Using 7 Tesla MRI and T2 Mapping. Journal of foot & ankle surgery. 2017 Jan;56(1):26-29 (2372402)

A flexible nested sodium and proton coil array with wideband matching for knee cartilage MRI at 3T
Brown, Ryan; Lakshmanan, Karthik; Madelin, Guillaume; Alon, Leeor; Chang, Gregory; Sodickson, Daniel K; Regatte, Ravinder R; Wiggins, Graham C. A flexible nested sodium and proton coil array with wideband matching for knee cartilage MRI at 3T. Magnetic resonance in medicine. 2016 Oct;76(4):1325-1334 (1817442)