Iman Osman

Biosketch / Results /

Iman Osman, M.D.

Professor; Associate Director, Perlmutter Cancer Center; Dir Interdisciplinary Melanoma Cooperative Grp
Ronald O. Perelman Department of Dermatology (Fac), Medicine (Medicine) and Urology (Administration)

Contact Info

Address
522 First Avenue
Floor 4th Room 405
Smilow Research Building
New York, NY 10016-6481

212-263-9076
212-263-9090
Iman.Osman@nyumc.org

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Education

1988-1991 — National Cancer Institute (Egypt): Fellowship in Medical Oncology, Clinical Fellowships
1994-1997 — Memorial Sloan-Kettering Cancer Center: Fellowship in Molecular Pathology, Clinical Fellowships
1997-1999 — Memorial Sloan-Kettering Cancer Center: Fellowship in Oncology Clinical Research, Clinical Fellowships

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Research Interests

Melanoma, Racial Disparity in Genitourinary Oncology

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All data from NYU Health Sciences Library Faculty Bibliography — -

Contact:
http://hsl.med.nyu.edu/faculty-bibliography-search

FBXW7 mutations in melanoma and a new therapeutic paradigm
Aydin, Iraz T; Melamed, Rachel D; Adams, Sarah J; Castillo-Martin, Mireia; Demir, Ahu; Bryk, Diana; Brunner, Georg; Cordon-Cardo, Carlos; Osman, Iman; Rabadan, Raul; Celebi, Julide Tok
2014 Jun;106(6):dju107-dju107 dju107, Journal of the National Cancer Institute
— id: 1065322, year: 2014, vol: 106, page: dju107, stat: Journal Article,

PP6C Hotspot Mutations in Melanoma Display Sensitivity to Aurora Kinase Inhibition
Gold, Heidi L; Wengrod, Jordan; de Miera, Eleazar Vega-Saenz; Wang, Ding; Fleming, Nathaniel; Sikkema, Lisa; Kirchhoff, Tomas; Hochman, Tsivia; Goldberg, Judith D; Osman, Iman; Gardner, Lawrence B
2014 Mar;12(3):433-439, Molecular cancer research
— id: 883502, year: 2014, vol: 12, page: 433, stat: Journal Article,

Epithelial and stromal expression of miRNAs during prostate cancer progression
Ren, Qinghu; Liang, Jiaqian; Wei, Jianjun; Basturk, Olca; Wang, Jinhua; Daniels, Garrett; Gellert, Lan Lin; Li, Yirong; Shen, Ying; Osman, Iman; Zhao, Jun; Melamed, Jonathan; Lee, Peng
2014 ;6(4):329-339, American journal of translational research
— id: 1105942, year: 2014, vol: 6, page: 329, stat: Journal Article,

Enhanced immunohistochemical detection of neural infiltration in primary melanoma: is there a clinical value?
Scanlon, Patrick; Tian, Jaiying; Zhong, Judy; Silva, Ines; Shapiro, Richard; Pavlick, Anna; Berman, Russell; Osman, Iman; Darvishian, Farbod
2014 Apr;:155-156, Human pathology
— id: 1030852, year: 2014, vol: , page: 155, stat: Journal Article,

Impact of age on treatment of primary melanoma patients
Fleming, N H; Tian, J; De, Miera E V -S; Gold, H L; Darvishian, F; Pavlick, A C; Berman, R S; Shapiro, R L; Polsky, D; Osman, I
2013 20 May 2013;31(15):-, Journal of clinical oncology
— id: 451902, year: 2013, vol: 31, page: , stat: Journal Article,

Impact of age on the management of primary melanoma patients
Fleming, Nathaniel H; Tian, Jiaying; Vega-Saenz de Miera, Eleazar; Gold, Heidi; Darvishian, Farbod; Pavlick, Anna C; Berman, Russell S; Shapiro, Richard L; Polsky, David; Osman, Iman
2013 ;85(3):173-181, Oncology (New York)
— id: 573882, year: 2013, vol: 85, page: 173, stat: Journal Article,

In vivo Modeling and Molecular Characterization: A Path Toward Targeted Therapy of Melanoma Brain Metastasis
Gaziel-Sovran, Avital; Osman, Iman; Hernando, Eva
2013 ;3:127-127, Frontiers in oncology
— id: 394062, year: 2013, vol: 3, page: 127, stat: Journal Article,

The clinical and biologic impact of PPP6C mutations in melanoma
Gold, H L; Wengrod, J; Tian, J; Vega-Saenz, de Miera E; Nadeem, Z; Fleming, N H; Shapiro, R; Hernando-Monge, E; Gardner, L; Osman, I
2013 20 May 2013;31(15):-, Journal of clinical oncology
— id: 451882, year: 2013, vol: 31, page: , stat: Journal Article,

Mitotic Rate in Melanoma: Prognostic Value of Immunostaining and Computer-assisted Image Analysis
Hale, Christopher S; Qian, Meng; Ma, Michelle W; Scanlon, Patrick; Berman, Russell S; Shapiro, Richard L; Pavlick, Anna C; Shao, Yongzhao; Polsky, David; Osman, Iman; Darvishian, Farbod
2013 Jun;37(6):882-889, American journal of surgical pathology
— id: 346512, year: 2013, vol: 37, page: 882, stat: Journal Article,

Hedgehog pathway blockade inhibits melanoma cell growth in vitro and in vivo
O'Reilly, Kathryn E; de Miera, Eleazar Vega-Saenz; Segura, Miguel F; Friedman, Erica; Poliseno, Laura; Han, Sung Won; Zhong, Judy; Zavadil, Jiri; Pavlick, Anna; Hernando, Eva; Osman, Iman
2013 ;6(11):1429-1450, Pharmaceuticals
— id: 688062, year: 2013, vol: 6, page: 1429, stat: Journal Article,

Targeting BET proteins in melanoma: A novel treatment approach
Paoluzzi, L; Segura, M F; Fontanals-Cirera, B; Gaziel-Sovran, A; Guijarro, M V; Hanniford, D; Gonzales-Gomez, P; Zhang, W; Zhang, G; Darvishian, F; Ohlmeyer, M; Osman, I; Zhou, M -M; Hernando, E
2013 20 May 2013;31(15):-, Journal of clinical oncology
— id: 451862, year: 2013, vol: 31, page: , stat: Journal Article,

Analysis of plasma-based BRAF and NRAS mutation detection in patients with stage III and IV melanoma
Polsky, D; Tadepalli, J S; Hafner, S; Chang, G; Fleming, N H; Shao, Y; Darvishian, F; Pavlick, A C; Berman, R S; Shapiro, R L; Osman, I; Spittle, C
2013 20 May 2013;31(15):-, Journal of clinical oncology
— id: 451912, year: 2013, vol: 31, page: , stat: Journal Article,

Clinicopathological characteristics at primary melanoma diagnosis as risk factors for brain metastasis
Qian, Meng; Ma, Michelle W; Fleming, Nathaniel H; Lackaye, Daniel J; Hernando, Eva; Osman, Iman; Shao, Yongzhao
2013 Dec;23(6):461-467, Melanoma research
— id: 598572, year: 2013, vol: 23, page: 461, stat: Journal Article,

Genetic variation in immunomodulatory genes as markers of melanoma recurrence-free and overall survival
Rendleman, J; Shang, S; Shields, J; Adaniel, C; Fleming, N H; Shapiro, R; Berman, R S; Pavlick, A C; Shao, Y; Osman, I; Kirchhoff, T
2013 20 May 2013;31(15):-, Journal of clinical oncology
— id: 451922, year: 2013, vol: 31, page: , stat: Journal Article,

Melanoma risk loci as determinants of melanoma recurrence and survival
Rendleman, Justin; Shang, Shulian; Dominianni, Christine; Shields, Jerry F; Scanlon, Patrick; Adaniel, Christina; Desrichard, Alexis; Ma, Michelle; Shapiro, Richard; Berman, Russell; Pavlick, Anna; Polsky, David; Shao, Yongzhao; Osman, Iman; Kirchhoff, Tomas
2013 Nov;11(1):279-279, Journal of translational medicine
— id: 617512, year: 2013, vol: 11, page: 279, stat: Journal Article,

BRD4 Sustains Melanoma Proliferation and Represents a New Target for Epigenetic Therapy
Segura, Miguel F; Fontanals-Cirera, Barbara; Gaziel-Sovran, Avital; Guijarro, Maria V; Hanniford, Doug; Zhang, Guangtao; Gonzalez-Gomez, Pilar; Morante, Marta; Jubierre, Luz; Zhang, Weijia; Darvishian, Farbod; Ohlmeyer, Michael; Osman, Iman; Zhou, Ming-Ming; Hernando, Eva
2013 Oct;73(20):6264-6276, Cancer research
— id: 573772, year: 2013, vol: 73, page: 6264, stat: Journal Article,

Melanoma recurrence risk stratification using Bayesian systems biology modeling
Styrmisdottir, E L; Scanlon, P; Hanniford, D; Eberhardt, J; Jones, T; Hernando, E; Osman, I
2013 20 May 2013;31(15):-, Journal of clinical oncology
— id: 451872, year: 2013, vol: 31, page: , stat: Journal Article,

Skin disease in individuals with liver and kidney transplants: influence of skin phototype and transplanted organ
Vuong, Charlotte H; Brauer, Jeremy A; Hochman, Tsivia; Teperman, Lewis; Osman, Iman; Stein, Jennifer A
2013 Oct;39(10):1539-1543, Dermatologic surgery
— id: 573682, year: 2013, vol: 39, page: 1539, stat: Journal Article,

T-cell receptor affinity and avidity defines antitumor response and autoimmunity in T-cell immunotherapy
Zhong, Shi; Malecek, Karolina; Johnson, Laura A; Yu, Zhiya; Vega-Saenz de Miera, Eleazar; Darvishian, Farbod; McGary, Katelyn; Huang, Kevin; Boyer, Josh; Corse, Emily; Shao, Yongzhao; Rosenberg, Steven A; Restifo, Nicholas P; Osman, Iman; Krogsgaard, Michelle
2013 Apr;110(17):6973-6978, Proceedings of the National Academy of Sciences of the United States of America
— id: 304932, year: 2013, vol: 110, page: 6973, stat: Journal Article,

TILs in metastatic melanoma tumors: A biomarker for immunotherapy?
Chandra, S; Ding, Y; Ma, M W; Bannan, M; Darvishian, F; Berman, R S; Shapiro, R; Krogsgaard, M; Osman, I; Pavlick, A C
2012 20 May 2012;30(15):-, Journal of clinical oncology
— id: 249972, year: 2012, vol: 30, page: , stat: Journal Article,

Development of five new melanoma low passage cell lines representing the clinical and genetic profile of their tumors of origin
de Miera, Eleazar Vega-Saenz; Friedman, Erica B; Greenwald, Holly S; Perle, Mary A; Osman, Iman
2012 May;25(3):395-397, Pigment cell & melanoma research
— id: 164344, year: 2012, vol: 25, page: 395, stat: Journal Article,

Elucidating distinct tumorigenic pathways in nodular versus superficial spreading melanoma
Farhadian, J A; O'Reilly, K E; De, Miera E V -S; Ye, F; Zavadil, J; Taunton, J; Zhang, D Y; Osman, I
2012 20 May 2012;30(15):-, Journal of clinical oncology
— id: 250032, year: 2012, vol: 30, page: , stat: Journal Article,

Identification of melanoma-specific alterations in cell surface glycosylation
Friedman, E B; Rakus, J F; Zavadil, J; Hernando, E; Mahal, L K; Osman, I
2012 20 May 2012;30(15):-, Journal of clinical oncology
— id: 249872, year: 2012, vol: 30, page: , stat: Journal Article,

Serum microRNAs as biomarkers for recurrence in melanoma
Friedman, Erica B; Shang, Shulian; de Miera, Eleazar Vega-Saenz; Fog, Jacob Ulrik; Teilum, Maria Wrang; Ma, Michelle W; Berman, Russell S; Shapiro, Richard L; Pavlick, Anna C; Hernando, Eva; Baker, Adam; Shao, Yongzhao; Osman, Iman
2012 ;10:155-155, Journal of translational medicine
— id: 180442, year: 2012, vol: 10, page: 155, stat: Journal Article,

Expression of miR-16 is not a suitable reference for analysis of serum microRNAs in melanoma patients
Friedman, Erica B; Shang, Shulian; Fleming, Nathaniel H; Vega-Saenz De Miera, Eleazar; Hernando, Eva; Shao, Yongzhao; Osman, Iman
2012 ;5:647-651, Journal of biomedical science & engineering
— id: 347512, year: 2012, vol: 5, page: 647, stat: Journal Article,

Superficial spreading and nodular melanoma are distinct biological entities: a challenge to the linear progression model
Greenwald, Holly S; Friedman, Erica B; Osman, Iman
2012 Feb;22(1):1-8, Melanoma research
— id: 149797, year: 2012, vol: 22, page: 1, stat: Journal Article,

Prognostic value of mitosis-specific antibodies and computer image analysis in calculating mitotic rate in melanoma
Hale, C; Qian, M; Ma, M W; Shao, Y; Polsky, D; Shapiro, R L; Berman, R S; Pavlick, A C; Osman, I; Darvishian, F
2012 20 May 2012;30(15):-, Journal of clinical oncology
— id: 249892, year: 2012, vol: 30, page: , stat: Journal Article,

Early alterations of microRNA expression to predict and modulate melanoma metastasis
Hernando, E; Hanniford, D; Shang, S; Segura, M F; Pavlick, A C; Berman, R S; Shapiro, R L; Darvishian, F; Osman, I; Shao, Y
2012 20 May 2012;30(15):-, Journal of clinical oncology
— id: 250022, year: 2012, vol: 30, page: , stat: Journal Article,

Single versus multiple primary melanomas: Old questions and new answers
Hwa C; Price LS; Belitskaya-Levy I; Ma MW; Shapiro RL; Berman RS; Kamino H; Darvishian F; Osman I; Stein JA
2012 Jan 13;:4184-4192, Cancer
— id: 150011, year: 2012, vol: , page: 4184, stat: Journal Article,

Impact of race on survival in patients with clinically nonmetastatic prostate cancer who deferred primary treatment
Koscuiszka M; Hatcher D; Christos PJ; Rose AE; Greenwald HS; Chiu YL; Taneja SS; Mazumdar M; Lee P; Osman I
2012 Oct 21;:3145-3152, Cancer
— id: 139502, year: 2012, vol: , page: 3145, stat: Journal Article,

MicroRNA alterations associated with BRAF status in melanoma
Ma, M W; Farhadian, J A; Friedman, E B; De, Miera E V -S; Hanniford, D; Segura, M F; Berman, R S; Shapiro, R L; Pavlick, A C; Zavadil, J; Hernando, E; Osman, I
2012 20 May 2012;30(15):-, Journal of clinical oncology
— id: 250002, year: 2012, vol: 30, page: , stat: Journal Article,

Immune response in melanoma: an in-depth analysis of the primary tumor and corresponding sentinel lymph node
Ma, Michelle W; Medicherla, Ratna C; Qian, Meng; Vega-Saenz de Miera, Eleazar; Friedman, Erica B; Berman, Russell S; Shapiro, Richard L; Pavlick, Anna C; Ott, Patrick A; Bhardwaj, Nina; Shao, Yongzhao; Osman, Iman; Darvishian, Farbod
2012 Jul;25(7):1000-1010, Modern pathology
— id: 171118, year: 2012, vol: 25, page: 1000, stat: Journal Article,

Challenging the current paradigm of melanoma progression: brain metastasis as isolated first visceral site
Ma, Michelle W; Qian, Meng; Lackaye, Daniel J; Berman, Russell S; Shapiro, Richard L; Pavlick, Anna C; Golfinos, John G; Parker, Erik C; Darvishian, Farbod; Hernando, Eva; Shao, Yongzhao; Osman, Iman
2012 Jul;14(7):849-858, Neuro-oncology
— id: 169477, year: 2012, vol: 14, page: 849, stat: Journal Article,

Targeting embryonic signaling pathways in melanoma
OReilly, K E; Poliseno, L; De, Miera E V -S; Friedman, E; Hernando, E; Osman, I
2012 15 Apr 2012;72(8):-, Cancer research
— id: 422452, year: 2012, vol: 72, page: , stat: Journal Article,

Histology-Specific MicroRNA Alterations in Melanoma
Poliseno, Laura; Haimovic, Adele; Segura, Miguel F; Hanniford, Douglas; Christos, Paul J; Darvishian, Farbod; Wang, Jinhua; Shapiro, Richard L; Pavlick, Anna C; Berman, Russell S; Hernando, Eva; Zavadil, Jiri; Osman, Iman
2012 Jul;132(7):1860-1868, Journal of investigative dermatology
— id: 169476, year: 2012, vol: 132, page: 1860, stat: Journal Article,

THE MELANOMA RISK LOCI AS DETERMINANTS OF MELANOMA PROGNOSIS
Rendleman, J.; Shang, S.; Brocia, C.; Ma, M.; Shapiro, R.; Berman, R.; Pavlick, A.; Shao, Y.; Osman, I.; Kirchhoff, T.
2012 SEP;23 9 9:363-363, Annals of oncology
— id: 181682, year: 2012, vol: 23 9 9, page: 363, stat: Journal Article,

The melanoma risk loci as determinants of melanoma prognosis
Rendleman, J; Shang, S; Brocia, C; Ma, M W; Shapiro, R L; Berman, R S; Pavlick, A C; Shao, Y; Osman, I; Kirchhoff, T
2012 20 May 2012;30(15):-, Journal of clinical oncology
— id: 306092, year: 2012, vol: 30, page: , stat: Journal Article,

BRD4 is a novel therapeutic target in melanoma
Segura, M F; Di, Micco R; Zhang, G; Zhang, W; Osman, I; Zhou, M -M; Hernando, E
2012 15 Apr 2012;72(8):-, Cancer research
— id: 422432, year: 2012, vol: 72, page: , stat: Journal Article,

MicroRNA and cutaneous melanoma: from discovery to prognosis and therapy
Segura, Miguel F; Greenwald, Holly S; Hanniford, Doug; Osman, Iman; Hernando, Eva
2012 Oct;33(10):1823-1832, Carcinogenesis
— id: 182332, year: 2012, vol: 33, page: 1823, stat: Journal Article,

Unraveling the roles of the histone variant H2A.Z in melanoma progression
Vardabasso, C; Panda, T; Straub, T; Boenisch, C; Montagna, C; Verma, A; Kapoor, A; Segura, M; Duarte, L F; Hernando, E; Bhardwaj, N; Osman, I; Sosman, J A; Hake, S B; Bernstein, E
2012 November 2012;25(6):894-894, Pigment cell & melanoma research
— id: 241402, year: 2012, vol: 25, page: 894, stat: Journal Article,

Roles of Polo-like kinase 3 in suppressing tumor angiogenesis
Xu, Dazhong; Wang, Qi; Jiang, Yongping; Zhang, Yanxi; Vega-Saenzdemiera, Eleazar; Osman, Iman; Dai, Wei
2012 ;1(1):5-5, Experimental hematology & oncology
— id: 197492, year: 2012, vol: 1, page: 5, stat: Journal Article,

Intra- and Inter-Tumor Heterogeneity of BRAFMutations in Primary and Metastatic Melanoma
Yancovitz, Molly; Litterman, Adam; Yoon, Joanne; Ng, Elise; Shapiro, Richard L; Berman, Russell S; Pavlick, Anna C; Darvishian, Farbod; Christos, Paul; Mazumdar, Madhu; Osman, Iman; Polsky, David
2012 ;7(1):e29336-e29336, PLoS one
— id: 149812, year: 2012, vol: 7, page: e29336, stat: Journal Article,

miR-30b/30d Regulation of GalNAc Transferases Enhances Invasion and Immunosuppression during Metastasis
Gaziel-Sovran, Avital; Segura, Miguel F; Di Micco, Raffaella; Collins, Mary K; Hanniford, Douglas; Vega-Saenz de Miera, Eleazar; Rakus, John F; Dankert, John F; Shang, Shulian; Kerbel, Robert S; Bhardwaj, Nina; Shao, Yongzhao; Darvishian, Farbod; Zavadil, Jiri; Erlebacher, Adrian; Mahal, Lara K; Osman, Iman; Hernando, Eva
2011 Jul 12;20(1):104-118, Cancer cell
— id: 135264, year: 2011, vol: 20, page: 104, stat: Journal Article,

microRNA Associated with Aggressive Prostate Cancer in Racial Disparity
Huang, H.; Wu, X.; Zhou, L.; Li, Y.; Basturk, O.; Ostrer, H.; Freedland, S.; Osman, I.; Reuter, V.; Melamed, J.; Lee, P.
2011 FEB ;91(6):199A-199A, Laboratory investigation
— id: 134484, year: 2011, vol: 91, page: 199A, stat: Journal Article,

microRNA Associated with Aggressive Prostate Cancer in Racial Disparity
Huang, H.; Wu, X.; Zhou, L.; Li, Y.; Basturk, O.; Ostrer, H.; Freedland, S.; Osman, I.; Reuter, V.; Melamed, J.; Lee, P.
2011 FEB ;24(11):199A-199A, Modern pathology
— id: 132755, year: 2011, vol: 24, page: 199A, stat: Journal Article,

Efficient in vivo microRNA targeting of liver metastasis
Huynh, C; Segura, M F; Gaziel-Sovran, A; Menendez, S; Darvishian, F; Chiriboga, L; Levin, B; Meruelo, D; Osman, I; Zavadil, J; Marcusson, E G; Hernando, E
2011 Mar 24;30(12):1481-1488, Oncogene
— id: 138159, year: 2011, vol: 30, page: 1481, stat: Journal Article,

Correction: The Novel Gamma Secretase Inhibitor RO4929097 Reduces the Tumor Initiating Potential of Melanoma
Huynh, Chanh; Poliseno, Laura; Segura, Miguel F; Medicherla, Ratna; Haimovic, Adele; Menendez, Silvia; Shang, Shulian; Pavlick, Anna; Shao, Yongzhao; Darvishian, Farbod; Boylan, John F; Osman, Iman; Hernando, Eva
2011 ;6(11):?-?, PLoS one
— id: 141637, year: 2011, vol: 6, page: ?, stat: Journal Article,

The Novel Gamma Secretase Inhibitor RO4929097 Reduces the Tumor Initiating Potential of Melanoma
Huynh, Chanh; Poliseno, Laura; Segura, Miguel F; Medicherla, Ratna; Haimovic, Adele; Menendez, Silvia; Shang, Shulian; Pavlick, Anna; Shao, Yongzhao; Darvishian, Farbod; Boylan, John F; Osman, Iman; Hernando, Eva
2011 ;6(9):e25264-e25264, PLoS one
— id: 138712, year: 2011, vol: 6, page: e25264, stat: Journal Article,

Metastatic balloon cell malignant melanoma: a case report and literature review
Lee, Lili; Zhou, Fang; Simms, Anthony; Wieczorek, Rosemary; Fang, Yanan; Subietas-Mayol, Antonio; Wang, Beverly; Heller, Patricia; Huang, Hongying; Pei, Zhiheng; Osman, Iman; Meehan, Shane; Lee, Peng
2011 Mar;4(3):315-321, International journal of clinical & experimental pathology
— id: 133175, year: 2011, vol: 4, page: 315, stat: Journal Article,

Natura-alpha targets forkhead box m1 and inhibits androgen-dependent and -independent prostate cancer growth and invasion
Li, Yirong; Ligr, Martin; McCarron, James P; Daniels, Garrett; Zhang, David; Zhao, Xin; Ye, Fei; Wang, Jinhua; Liu, Xiaomei; Osman, Iman; Mencher, Simon K; Lepor, Hebert; Wang, Long G; Ferrari, Anna; Lee, Peng
2011 Jul;17(13):4414-4424, Clinical cancer research
— id: 174599, year: 2011, vol: 17, page: 4414, stat: Journal Article,

Impact of population genetic substructure on association studies and risk assessment for melanoma
Lobach I; Belitskaya-Levy I; Goldberg JD; Ostrer H; Berman RS; Pavlick AC; Shapiro RL; Osman I; Manga P
2011 ;29(Suppl):?-? #8521, Journal of clinical oncology
— id: 132473, year: 2011, vol: 29, page: ?, stat: Journal Article,

microRNA-214 contributes to melanoma tumor progression through suppression of TFAP2C
Penna E.; Orso F.; Cimino D.; Tenaglia E.; Lembo A.; Quaglino E.; Poliseno L.; Haimovic A.; Osella S.; De Pitta C.; Pinatel E.; Stadler M.; Provero P.; Bernengo M.G.; Osman I.; Taverna D.
2011 ;278:228-228, FEBS journal
— id: 136626, year: 2011, vol: 278, page: 228, stat: Journal Article,

microRNA-214 contributes to melanoma tumour progression through suppression of TFAP2C
Penna, Elisa; Orso, Francesca; Cimino, Daniela; Tenaglia, Enrico; Lembo, Antonio; Quaglino, Elena; Poliseno, Laura; Haimovic, Adele; Osella-Abate, Simona; De Pitta, Cristiano; Pinatel, Eva; Stadler, Michael B; Provero, Paolo; Bernengo, Maria Grazia; Osman, Iman; Taverna, Daniela
2011 May;30(10):1990-2007, EMBO journal
— id: 159239, year: 2011, vol: 30, page: 1990, stat: Journal Article,

Deletion of PTENP1 Pseudogene in Human Melanoma
Poliseno, Laura; Haimovic, Adele; Christos, Paul J; Vega Y Saenz de Miera, Eleazar C; Shapiro, Richard; Pavlick, Anna; Berman, Russell S; Darvishian, Farbod; Osman, Iman
2011 Dec;131(12):2497-2500, Journal of investigative dermatology
— id: 141068, year: 2011, vol: 131, page: 2497, stat: Journal Article,

Integrative genomics identifies molecular alterations that challenge the linear model of melanoma progression
Rose AE; Poliseno L; Wang J; Clark M; Pearlman A; Wang G; Vega Y Saenz de Miera EC; Medicherla R; Christos PJ; Shapiro RL; Pavlick AC; Darvishian F; Zavadil J; Polsky D; Hernando E; Ostrer H; Osman I
2011 Apr 1;71(7):2561-2571, Cancer research
— id: 124135, year: 2011, vol: 71, page: 2561, stat: Journal Article,

Clinical Relevance of Detection of Lymphovascular Invasion in Primary Melanoma Using Endothelial Markers D2-40 and CD34
Rose, Amy E; Christos, Paul J; Lackaye, Dan; Shapiro, Richard L; Berman, Russell; Mazumdar, Madhu; Kamino, Hideko; Osman, Iman; Darvishian, Farbod
2011 Oct;35(10):1441-1449, American journal of surgical pathology
— id: 137842, year: 2011, vol: 35, page: 1441, stat: Journal Article,

Clinical relevance of SKP2 alterations in metastatic melanoma
Rose, Amy E; Wang, Guimin; Hanniford, Douglas; Monni, Stefano; Tu, Ting; Shapiro, Richard L; Berman, Russell S; Pavlick, Anna C; Pagano, Michele; Darvishian, Farbod; Mazumdar, Madhu; Hernando, Eva; Osman, Iman
2011 Feb;24(1):197-206, Pigment cell & melanoma research
— id: 138133, year: 2011, vol: 24, page: 197, stat: Journal Article,

Enrollment in clinical trials correlates with improved survival in metastatic melanoma
Seetharamu, Nagashree; Tu, Ting J; Christos, Paul; Ott, Patrick A; Berman, Russell S; Shapiro, Richard L; Osman, Iman; Pavlick, Anna C
2011 ;81(5-6):403-409, Oncology (New York)
— id: 157480, year: 2011, vol: 81, page: 403, stat: Journal Article,

A high proliferative index of recurrent melanoma is associated with worse survival
Tu, Ting J; Ma, Michelle W; Monni, Stefano; Rose, Amy E; Yee, Herman; Darvishian, Farbod; Polsky, David; Berman, Russell S; Shapiro, Richard L; Pavlick, Anna C; Mazumdar, Madhu; Osman, Iman
2011 ;80(3-4):181-187, Oncology (New York)
— id: 135575, year: 2011, vol: 80, page: 181, stat: Journal Article,

Regulation of HMGA1 expression by microRNA296 affects prostate cancer growth and invasion
Wei JJ; Wu X; Peng Y; Shi G; Olca B; Yang X; Daniels G; Osman I; Ouyang J; Hernando E; Pellicer A; Rhim J; Melamed J; Lee P
2011 Mar 15;17(6):1297-1305, Clinical cancer research
— id: 115464, year: 2011, vol: 17, page: 1297, stat: Journal Article,

Impact of socioeconomic status and sociodemographic factors on melanoma presentation among ethnic minorities
Wich, Lindsay G; Ma, Michelle W; Price, Leah S; Sidash, Stanislav; Berman, Russell S; Pavlick, Anna C; Miller, George; Sarpel, Umut; Goldberg, Judith D; Osman, Iman
2011 Jun;36(3):461-468, Journal of community health
— id: 138281, year: 2011, vol: 36, page: 461, stat: Journal Article,

Clinical variables and primary tumor characteristics predictive of the development of melanoma brain metastases and post-brain metastases survival
Zakrzewski, Jan; Geraghty, Laurel N; Rose, Amy E; Christos, Paul J; Mazumdar, Madhu; Polsky, David; Shapiro, Richard; Berman, Russell; Darvishian, Farbod; Hernando, Eva; Pavlick, Anna; Osman, Iman
2011 Apr 15;117(8):1711-1720, Cancer
— id: 130314, year: 2011, vol: 117, page: 1711, stat: Journal Article,

Androgen receptor expression is associated with prostate cancer-specific survival in castrate patients with metastatic disease
Donovan, Michael J; Osman, Iman; Khan, Faisal M; Vengrenyuk, Yevgen; Capodieci, Paola; Koscuiszka, Michael; Anand, Aseem; Cordon-Cardo, Carlos; Costa, Jose; Scher, Howard I
2010 Feb 1;105(4):462-467, BJU international
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Increased shedding of HU177 correlates with worse prognosis in primary melanoma
Hamilton, Heather K; Rose, Amy E; Christos, Paul J; Shapiro, Richard L; Berman, Russell S; Mazumdar, Madhu; Ma, Michelle W; Krich, Daniel; Liebes, Leonard; Brooks, Peter C; Osman, Iman
2010 Feb 23;8(1):19-19, Journal of translational medicine
— id: 107363, year: 2010, vol: 8, page: 19, stat: Journal Article,

The histone variant macroH2A suppresses melanoma progression through regulation of CDK8
Kapoor, Avnish; Goldberg, Matthew S; Cumberland, Lara K; Ratnakumar, Kajan; Segura, Miguel F; Emanuel, Patrick O; Menendez, Silvia; Vardabasso, Chiara; Leroy, Gary; Vidal, Claudia I; Polsky, David; Osman, Iman; Garcia, Benjamin A; Hernando, Eva; Bernstein, Emily
2010 Dec 23;468(7327):1105-1109, Nature
— id: 134348, year: 2010, vol: 468, page: 1105, stat: Journal Article,

New gamma-secretase inhibitor (RO4929097) targeting notch signaling in melanoma
Osman, I; Poliseno, L; Huynh, C T; Segura, M F; Medicherla, R; Menendez, S; Rose, A E; Pavlick, A C; Boylan, J; Hernando, E
2010 November 2010;11:61-62, Current treatment options in oncology
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A Phase II Trial of Sorafenib in Metastatic Melanoma with Tissue Correlates
Ott, Patrick A; Hamilton, Anne; Min, Christina; Safarzadeh-Amiri, Sara; Goldberg, Lauren; Yoon, Joanne; Yee, Herman; Buckley, Michael; Christos, Paul J; Wright, John J; Polsky, David; Osman, Iman; Liebes, Leonard; Pavlick, Anna C
2010 ;5(12):e15588-e15588, PLoS one
— id: 117357, year: 2010, vol: 5, page: e15588, stat: Journal Article,

Novel PRKAR1A gene mutations in Carney Complex
Pan, Lorraine; Peng, Lan; Jean-Gilles, J; Zhang, Ximin; Wieczorek, Rosemary; Jain, Shilpa; Levine, Vicki; Osman, Iman; Prieto, Victor G; Lee, Peng
2010 ;3(5):545-548, International journal of clinical & experimental pathology
— id: 110695, year: 2010, vol: 3, page: 545, stat: Journal Article,

Identification of tyrosinase polymorphisms for use in melanoma risk assessment
Pervolaraki E; Lobach I; Belitskaya-Levy I; Ostrer H; Goldberg JD; Polsky D; Shapiro RL; Berman RS; Osman I; Manga P
2010 ;28(15S):?-? #8570, Journal of clinical oncology
— id: 111554, year: 2010, vol: 28, page: ?, stat: Journal Article,

Copy number and gene expression differences between African American and Caucasian American prostate cancer
Rose, Amy E; Satagopan, Jaya M; Oddoux, Carole; Zhou, Qin; Xu, Ruliang; Olshen, Adam B; Yu, Jessie Z; Dash, Atreya; Jean-Gilles, Jerome; Reuter, Victor; Gerald, William L; Lee, Peng; Osman, Iman
2010 ;8(1):70-70, Journal of translational medicine
— id: 111525, year: 2010, vol: 8, page: 70, stat: Journal Article,

Melanoma MicroRNA Signature Predicts Post-Recurrence Survival
Segura, Miguel F; Belitskaya-Levy, Ilana; Rose, Amy E; Zakrzewski, Jan; Gaziel, Avital; Hanniford, Douglas; Darvishian, Farbod; Berman, Russell S; Shapiro, Richard L; Pavlick, Anna C; Osman, Iman; Hernando, Eva
2010 Mar 1;16(5):1577-1586, Clinical cancer research
— id: 107357, year: 2010, vol: 16, page: 1577, stat: Journal Article,

Clinical variables and primary tumor characteristics predictive of the development of melanoma brain metastases and post-brain metastases survival
Zakrzewski J; Geraghty LN; Rose AE; Christos PJ; Mazumdar M; Polsky D; Shapiro R; Berman R; Darvishian F; Hernando E; Pavlick A; Osman I
2010 Nov 8;:?-?, Cancer
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The Expression of GPR 30, a G Protein-Coupled Receptor, in Prostate Cancer
Zhang, M; Lam, HM; Yu, MQ; Wang, JH; Ouyang, B; Jain, S; Daniels, G; Reuter, V; Gopalan, A; Osman, I; Lee, P; Ho, SM
2010 FEB ;23(3):231A-231A, Modern pathology
— id: 109938, year: 2010, vol: 23, page: 231A, stat: Journal Article,

The Expression of GPR 30, a G Protein-Coupled Receptor, in Prostate Cancer
Zhang, M; Lam, HM; Yu, MQ; Wang, JH; Ouyang, B; Jain, S; Daniels, G; Reuter, V; Gopalan, A; Osman, I; Lee, P; Ho, SM
2010 FEB ;90(11):231A-231A, Laboratory investigation
— id: 109957, year: 2010, vol: 90, page: 231A, stat: Journal Article,

Immune profile and mitotic index of metastatic melanoma lesions enhance clinical staging in predicting patient survival
Bogunovic, Dusan; O'Neill, David W; Belitskaya-Levy, Ilana; Vacic, Vladimir; Yu, Yi-Lo; Adams, Sylvia; Darvishian, Farbod; Berman, Russell; Shapiro, Richard; Pavlick, Anna C; Lonardi, Stefano; Zavadil, Jiri; Osman, Iman; Bhardwaj, Nina
2009 Dec 1;106(48):20429-20434, Proceedings of the National Academy of Sciences of the United States of America
— id: 105312, year: 2009, vol: 106, page: 20429, stat: Journal Article,

Effect of celastrol on temozolomide cytotoxicity in melanoma cells and inhibition of NF-kB signaling
Chen M.; Osman I.; Orlow S.J.
2009 ;27(15 Suppl 1):9076-9076, Journal of clinical oncology
— id: 111808, year: 2009, vol: 27, page: 9076, stat: Journal Article,

Antifolate activity of pyrimethamine enhances temozolomide-induced cytotoxicity in melanoma cells
Chen, Ming; Osman, Iman; Orlow, Seth J
2009 May;7(5):703-712, Molecular cancer research
— id: 99017, year: 2009, vol: 7, page: 703, stat: Journal Article,

Celastrol Synergistically Enhances Temozolomide Cytotoxicity in Melanoma Cells
Chen, Ming; Rose, Amy E; Doudican, Nicole; Osman, Iman; Orlow, Seth J
2009 Dec;7(12):1946-1953, Molecular cancer research
— id: 105467, year: 2009, vol: 7, page: 1946, stat: Journal Article,

Effect of mebendazole on melanoma xenograft growth through targeting of bcl-2
Doudican N.A.; Pennell R.; Tu T.; Liebes L.; Pavlick A.; Berman R.; Shapiro R.; Goldberg J.D.; Osman I.; Orlow S.
2009 ;27(15 Suppl 1):9075-9075, Journal of clinical oncology
— id: 111807, year: 2009, vol: 27, page: 9075, stat: Journal Article,

Association of MDM2 SNP309, age of onset, and gender in cutaneous melanoma
Firoz, Elnaz F; Warycha, Melanie; Zakrzewski, Jan; Pollens, Danuta; Wang, Guimin; Shapiro, Richard; Berman, Russell; Pavlick, Anna; Manga, Prashiela; Ostrer, Harry; Celebi, Julide Tok; Kamino, Hideko; Darvishian, Farbod; Rolnitzky, Linda; Goldberg, Judith D; Osman, Iman; Polsky, David
2009 Apr 1;15(7):2573-2580, Clinical cancer research
— id: 104875, year: 2009, vol: 15, page: 2573, stat: Journal Article,

Molecular mechanisms involving prostate cancer racial disparity
Hatcher, David; Daniels, Garrett; Osman, Iman; Lee, Peng
2009 ;1(3):235-248, American journal of translational research
— id: 105528, year: 2009, vol: 1, page: 235, stat: Journal Article,

Detection of BRAF kinase mutations in melanoma, ovarian, and prostate carcinomas: Evidence for tumor heterogeneity in clinical samples
Litterman A.J.; Yancovitz M.; Shapiro R.; Berman R.; Pavlick A.; Daarvishian F.; Blank S.; Lee P.; Osman I.; Polsky D.
2009 ;27(15 Suppl 1):11031-11031, Journal of clinical oncology
— id: 111809, year: 2009, vol: 27, page: 11031, stat: Journal Article,

Developing genetic markers for melanoma risk assessment
Manga P.; Goldberg J.D.; Belitskaya-Levy I.; Lobach I.; Polsky D.; Pavlick A.; Shapiro R.; Berman R.; Osman I.; Ostrer H.
2009 ;27(15 Suppl 1):9046-9046, Journal of clinical oncology
— id: 111805, year: 2009, vol: 27, page: 9046, stat: Journal Article,

Phosphorylated 4E-BP1 is associated with poor survival in melanoma
O'Reilly, Kathryn E; Warycha, Melanie; Davies, Michael A; Rodrik, Vanessa; Zhou, Xi K; Yee, Herman; Polsky, David; Pavlick, Anna C; Rosen, Neal; Bhardwaj, Nina; Mills, Gordon; Osman, Iman
2009 Apr 15;15(8):2872-2878, Clinical cancer research
— id: 99295, year: 2009, vol: 15, page: 2872, stat: Journal Article,

The unique molecular signatures of nodular and superficial spreading melanoma
Rose A.E.; Wang J.; Pearlman A.; Doudican N.; Hernando E.; J. Orlow S.; Polsky D.; Ostrer H.; Osman I.
2009 ;27(15 Suppl 1):9047-9047, Journal of clinical oncology
— id: 111806, year: 2009, vol: 27, page: 9047, stat: Journal Article,

Aberrant miR-182 expression promotes melanoma metastasis by repressing FOXO3 and microphthalmia-associated transcription factor
Segura, Miguel F; Hanniford, Douglas; Menendez, Silvia; Reavie, Linsey; Zou, Xuanyi; Alvarez-Diaz, Silvia; Zakrzewski, Jan; Blochin, Elen; Rose, Amy; Bogunovic, Dusan; Polsky, David; Wei, Jianjun; Lee, Peng; Belitskaya-Levy, Ilana; Bhardwaj, Nina; Osman, Iman; Hernando, Eva
2009 Feb 10;106(6):1814-1819, Proceedings of the National Academy of Sciences of the United States of America
— id: 92154, year: 2009, vol: 106, page: 1814, stat: Journal Article,

Evaluation of the melanocortin-1-receptor gene in melanoma predisposition, progression and recurrence
Sidash S; Ostrer H; Goldberg JD; Belitskaya-Levy I; Lobach I; Polsky D; Shapiro RL; Berman RS; Osman I; Manga P
2009 ;27:15S-15S, Journal of clinical oncology
— id: 102306, year: 2009, vol: 27, page: 15S, stat: Journal Article,

MDM2 Expression and Regulation in Prostate Cancer Racial Disparity
Wang, Guimin; Firoz, Elnaz F; Rose, Amy; Blochin, Elen; Christos, Paul; Pollens, Danuta; Mazumdar, Madhu; Gerald, William; Oddoux, Carole; Lee, Peng; Osman, Iman
2009 ;2(4):353-360, International journal of clinical & experimental pathology
— id: 92155, year: 2009, vol: 2, page: 353, stat: Journal Article,

Increased expression of histone deacetylaces (HDACs) and inhibition of prostate cancer growth and invasion by HDAC inhibitor SAHA
Wang, Longgui; Zou, Xuanyi; Berger, Aaron D; Twiss, Christian; Peng, Yi; Li, Yirong; Chiu, Jason; Guo, Hongfeng; Satagopan, Jaya; Wilton, Andrew; Gerald, William; Basch, Ross; Wang, Zhengxin; Osman, Iman; Lee, Peng
2009 ;1(1):62-71, American journal of translational research
— id: 115887, year: 2009, vol: 1, page: 62, stat: Journal Article,

Changes in the presentation of nodular and superficial spreading melanomas over 35 years
Warycha, M; Kopf, A; Polsky, D; Osman, I
2009 MAR ;60(3):AB11-AB11, Journal of the American Academy of Dermatology
— id: 97560, year: 2009, vol: 60, page: AB11, stat: Journal Article,

Metaanalysis of sentinel lymph node positivity in thin melanoma (<= 1 mm)
Warycha, M; Polsky, D; Osman, I; Mazumdar, M
2009 MAR ;60(3):AB10-AB10, Journal of the American Academy of Dermatology
— id: 97559, year: 2009, vol: 60, page: AB10, stat: Journal Article,

Meta-analysis of sentinel lymph node positivity in thin melanoma (</=1 mm)
Warycha, Melanie A; Zakrzewski, Jan; Ni, Quanhong; Shapiro, Richard L; Berman, Russell S; Pavlick, Anna C; Polsky, David; Mazumdar, Madhu; Osman, Iman
2009 Feb 15;115(4):869-879, Cancer
— id: 92156, year: 2009, vol: 115, page: 869, stat: Journal Article,

Developing a multidisciplinary prospective melanoma biospecimen repository to advance translational research
Wich, Lindsay G; Hamilton, Heather K; Shapiro, Richard L; Pavlick, Anna; Berman, Russell S; Polsky, David; Goldberg, Judith D; Hernando, Eva; Manga, Prashiela; Krogsgaard, Michelle; Kamino, Hideko; Darvishian, Farbod; Lee, Peng; Orlow, Seth J; Ostrer, Harry; Bhardwaj, Nina; Osman, Iman
2009 ;1(1):35-43, American journal of translational research
— id: 105566, year: 2009, vol: 1, page: 35, stat: Journal Article,

Stromal anti-apoptotic androgen receptor target gene c-FLIP in prostate cancer
Ye, Huihui; Li, Yirong; Melamed, Jonathan; Pearce, Patrice; Wei, Jianjun; Chiriboga, Luis; Wang, Zhengxin; Osman, Iman; Lee, Peng
2009 Feb;181(2):872-877, Journal of urology
— id: 92157, year: 2009, vol: 181, page: 872, stat: Journal Article,

Utility of lesion diameter in the clinical diagnosis of cutaneous melanoma
Abbasi, Naheed R; Yancovitz, Molly; Gutkowicz-Krusin, Dina; Panageas, Katherine S; Mihm, Martin C; Googe, Paul; King, Roy; Prieto, Victor; Osman, Iman; Friedman, Robert J; Rigel, Darrell S; Kopf, Alfred W; Polsky, David
2008 Apr;144(4):469-474, Archives of dermatology (1960)
— id: 78338, year: 2008, vol: 144, page: 469, stat: Journal Article,

Gene expression profile for metastatic melanoma and patient survival
Bogunovic D; O'Neill D; Adams S; Wang J; Darvishian F; Pavlick AC; Shapiro RL; Zavadil J; Osman I; Bhardwaj N
2008 May 20;26(Suppl):?-? #9049, Proceedings (American Society of Clinical Oncology)
— id: 106301, year: 2008, vol: 26, page: ?, stat: Journal Article,

Epidermal growth factor receptor activation in prostate cancer by three novel missense mutations
Cai, C Q; Peng, Y; Buckley, M T; Wei, J; Chen, F; Liebes, L; Gerald, W L; Pincus, M R; Osman, I; Lee, P
2008 May 15;27(22):3201-3210, Oncogene
— id: 76447, year: 2008, vol: 27, page: 3201, stat: Journal Article,

Impact of Socioeconomic Factors on Prostate Cancer Outcomes in Black Patients Treated with Surgery
Dash, Atreya; Lee, Peng; Zhou, Qin; Jean-Gilles, Jerome; Taneja, Samir; Satagopan, Jaya; Reuter, Victor; Gerald, William; Eastham, James; Osman, Iman
2008 Sep;72(3):641-646, Urology
— id: 76449, year: 2008, vol: 72, page: 641, stat: Journal Article,

Mebendazole induces apoptosis via Bcl-2 inactivation in chemoresistant melanoma cells
Doudican, Nicole; Rodriguez, Adrianna; Osman, Iman; Orlow, Seth J
2008 Aug;6(8):1308-1315, Molecular cancer research
— id: 86657, year: 2008, vol: 6, page: 1308, stat: Journal Article,

Polymorphisms of p53 and its negative regulator MDM2 in human melanoma
Firoz, EF; Warycha, M; Shapiro, R; Berman, R; Kamino, H; Darvishian, F; Rolnitzky, L; Goldberg, J; Osman, I; Polsky, D
2008 APR ;128(5):S226-S226, Journal of investigative dermatology
— id: 78655, year: 2008, vol: 128, page: S226, stat: Journal Article,

Frequent p16-independent inactivation of p14ARF in human melanoma
Freedberg, Daniel E; Rigas, Sushila H; Russak, Julie; Gai, Weiming; Kaplow, Margarita; Osman, Iman; Turner, Faye; Randerson-Moor, Juliette A; Houghton, Alan; Busam, Klaus; Timothy Bishop, D; Bastian, Boris C; Newton-Bishop, Julia A; Polsky, David
2008 Jun 4;100(11):784-795, Journal of the National Cancer Institute
— id: 79367, year: 2008, vol: 100, page: 784, stat: Journal Article,

Nucleofection is a highly effective gene transfer technique for human melanoma cell lines
Han, Sandra Y; Gai, Weiming; Yancovitz, Molly; Osman, Iman; Di Como, Charles J; Polsky, David
2008 May;17(5):405-411, Experimental dermatology
— id: 76778, year: 2008, vol: 17, page: 405, stat: Journal Article,

Shedding of distinct cryptic collagen epitope (HU177) in sera of melanoma patients
Ng, Bruce; Zakrzewski, Jan; Warycha, Melanie; Christos, Paul J; Bajorin, Dean F; Shapiro, Richard L; Berman, Russell S; Pavlick, Anna C; Polsky, David; Mazumdar, Madhu; Montgomery, Anthony; Liebes, Leonard; Brooks, Peter C; Osman, Iman
2008 Oct 1;14(19):6253-6258, Clinical cancer research
— id: 92160, year: 2008, vol: 14, page: 6253, stat: Journal Article,

Phase II trial of 17-allylamino-17-demethoxygeldanamycin in patients with metastatic melanoma
Solit, David B; Osman, Iman; Polsky, David; Panageas, Katherine S; Daud, Adil; Goydos, James S; Teitcher, Jerrold; Wolchok, Jedd D; Germino, F Joseph; Krown, Susan E; Coit, Daniel; Rosen, Neal; Chapman, Paul B
2008 Dec 15;14(24):8302-8307, Clinical cancer research
— id: 92158, year: 2008, vol: 14, page: 8302, stat: Journal Article,

Changes in the presentation of nodular and superficial spreading melanomas over 35 years
Warycha, Melanie A; Christos, Paul J; Mazumdar, Madhu; Darvishian, Farbod; Shapiro, Richard L; Berman, Russell S; Pavlick, Anna C; Kopf, Alfred W; Polsky, David; Osman, Iman
2008 Dec 15;113(12):3341-3348, Cancer
— id: 91976, year: 2008, vol: 113, page: 3341, stat: Journal Article,

Assessing the clinical utility of measuring Insulin-like Growth Factor Binding Proteins in tissues and sera of melanoma patients
Yu, Jessie Z; Warycha, Melanie A; Christos, Paul J; Darvishian, Farbod; Yee, Herman; Kaminio, Hideko; Berman, Russell S; Shapiro, Richard L; Buckley, Michael T; Liebes, Leonard F; Pavlick, Anna C; Polsky, David; Brooks, Peter C; Osman, Iman
2008 ;6:70-70, Journal of translational medicine
— id: 92159, year: 2008, vol: 6, page: 70, stat: Journal Article,

The histone deacetylase inhibitor belinostat (PXD101) suppresses bladder cancer cell growth in vitro and in vivo
Buckley, Michael T; Yoon, Joanne; Yee, Herman; Chiriboga, Luis; Liebes, Leonard; Ara, Gulshan; Qian, Xiaozhong; Bajorin, Dean F; Sun, Tung-Tien; Wu, Xue-Ru; Osman, Iman
2007 Oct 12;5(1):49-49, Journal of translational medicine
— id: 74320, year: 2007, vol: 5, page: 49, stat: Journal Article,

Identification of angiogenesis/metastases genes predicting chemoradiotherapy response in patients with laryngopharyngeal carcinoma
Ganly, Ian; Talbot, Simon; Carlson, Diane; Viale, Agnes; Maghami, Ellie; Osman, Iman; Sherman, Eric; Pfister, David; Chuai, Shaokun; Shaha, Ashok R; Kraus, Dennis; Shah, Jatin P; Socci, Nicholas D; Singh, Bhuvanesh
2007 Apr 10;25(11):1369-1376, Journal of clinical oncology
— id: 96941, year: 2007, vol: 25, page: 1369, stat: Journal Article,

Expression of the cancer/testis antigen NY-ESO-1 in primary and metastatic malignant melanoma (MM)--correlation with prognostic factors
Velazquez, Elsa F; Jungbluth, Achim A; Yancovitz, Molly; Gnjatic, Sacha; Adams, Sylvia; O'Neill, David; Zavilevich, Kira; Albukh, Tatyana; Christos, Paul; Mazumdar, Madhu; Pavlick, Anna; Polsky, David; Shapiro, Richard; Berman, Russell; Spira, Joanna; Busam, Klaus; Osman, Iman; Bhardwaj, Nina
2007 ;7:11-11, Cancer imunity
— id: 73347, year: 2007, vol: 7, page: 11, stat: Journal Article,

Clinical relevance of neutral endopeptidase (NEP/CD10) in melanoma
Velazquez, Elsa F; Yancovitz, Molly; Pavlick, Anna; Berman, Russell; Shapiro, Richard; Bogunovic, Dusan; O'Neill, David; Yu, Yi-Lo; Spira, Joanna; Christos, Paul J; Zhou, Xi Kathy; Mazumdar, Madhu; Nanus, David M; Liebes, Leonard; Bhardwaj, Nina; Polsky, David; Osman, Iman
2007 ;5:2-2, Journal of translational medicine
— id: 74679, year: 2007, vol: 5, page: 2, stat: Journal Article,

Role of radiologic imaging at the time of initial diagnosis of stage T1b-T3b melanoma
Yancovitz, Molly; Finelt, Nika; Warycha, Melanie A; Christos, Paul J; Mazumdar, Madhu; Shapiro, Richard L; Pavlick, Anna C; Osman, Iman; Polsky, David; Berman, Russell S
2007 Sep 1;110(5):1107-1114, Cancer
— id: 74405, year: 2007, vol: 110, page: 1107, stat: Journal Article,

Detection of mutant BRAF alleles in the plasma of patients with metastatic melanoma
Yancovitz, Molly; Yoon, Joanne; Mikhail, Maryann; Gai, Weiming; Shapiro, Richard L; Berman, Russell S; Pavlick, Anna C; Chapman, Paul B; Osman, Iman; Polsky, David
2007 Apr;9(2):178-183, Journal of molecular diagnostics
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Mutational profiling of protein kinases in prostate carcinoma
Andea, A; Osman, I; Scardino, P; Scher, H; Gerald, W
2006 JUN 20 ;24(18):250S-250S, Journal of clinical oncology
— id: 69298, year: 2006, vol: 24, page: 250S, stat: Journal Article,

Differences in clinicopathologic features of prostate cancer between black and white patients treated in the 1990s and 2000s
Berger, Aaron D; Satagopan, Jaya; Lee, Peng; Taneja, Samir S; Osman, Iman
2006 Jan;67(1):120-124, Urology
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Novel mutations in tyrosine kinase domain of epidermal growth factor receptor in prostate cancer
Douglas, D; Zhong, H; Ro, J; Oddoux, C; Pincus, M; Satagopan, J; Gerald, W; Schei, H; Lee, P; Osman, I
2006 JUN 20 ;24(18):244S-244S, Journal of clinical oncology
— id: 69297, year: 2006, vol: 24, page: 244S, stat: Journal Article,

Novel mutations of epidermal growth factor receptor in localized prostate cancer
Douglas, Diah A; Zhong, Hong; Ro, Jae Y; Oddoux, Carole; Berger, Aaron D; Pincus, Matthew R; Satagopan, Jaya M; Gerald, William L; Scher, Howard I; Lee, Peng; Osman, Iman
2006 ;11:2518-2525, Frontiers in biosciences
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Novel blood biomarkers of human urinary bladder cancer
Osman, Iman; Bajorin, Dean F; Sun, Tung-Tien; Zhong, Hong; Douglas, Diah; Scattergood, Joseph; Zheng, Run; Han, Mark; Marshall, K Wayne; Liew, Choong-Chin
2006 Jun 1;12(11 Pt 1):3374-3380, Clinical cancer research
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Loss of neutral endopeptidase and activation of protein kinase B (Akt) is associated with prostate cancer progression
Osman, Iman; Dai, Jie; Mikhail, Maryann; Navarro, Daniel; Taneja, Samir S; Lee, Peng; Christos, Paul; Shen, Ruoqian; Nanus, David M
2006 Dec 1;107(11):2628-2636, Cancer
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Altered patterns of RB expression define groups of soft tissue sarcoma patients with distinct biological and clinical behavior
Polsky, D; Mastorides, S; Kim, D; Dudas, M; Leon, L; Leung, D; Woodruff, J M; Brennan, M F; Osman, I; Cordon-Cardo, C
2006 Jul;21(7):743-752, Histology & histopathology
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BRAF mutation predicts sensitivity to MEK inhibition
Solit, David B; Garraway, Levi A; Pratilas, Christine A; Sawai, Ayana; Getz, Gad; Basso, Andrea; Ye, Qing; Lobo, Jose M; She, Yuhong; Osman, Iman; Golub, Todd R; Sebolt-Leopold, Judith; Sellers, William R; Rosen, Neal
2006 Jan 19;439(7074):358-362, Nature
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Expression of cancer testis (CT) antigen NY-ESO-1 in primary and metastatic malignant melanoma (MM), correlation with prognostic factors and potential role in a melanoma vaccine
Velazquez, EF; Jungbluth, AA; Osman, I; Yancovitz, M; Adams, S; O'Neill, D; Zavilevich, K; Albukh, T; Pavlick, A; Polsky, D; Shapiro, R; Berman, R; Spira, J; Busam, K; Bhardwaj, N
2006 JAN ;19(4):89A-89A, Modern pathology
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Expression of cancer testis (CT) antigen NY-ESO-1 in primary and metastatic malignant melanoma (MM), correlation with prognostic factors and potential role in a melanoma vaccine
Velazquez, EF; Jungbluth, AA; Osman, I; Yancovitz, M; Adams, S; O'Neill, D; Zavilevich, K; Albukh, T; Pavlick, A; Polsky, D; Shapiro, R; Berman, R; Spira, J; Busam, K; Bhardwaj, N
2006 JAN ;86(4):89A-89A, Laboratory investigation
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Neutral endopeptidase (NEP) overexpression is associated with progression in malignant melanoma (MM) and is a potential target of treatment
Velazquez, EF; Yancovitz, M; Sorhaindo, L; Bogunovic, D; O'Neill, D; Shapiro, R; Pavlick, A; Berman, R; Bhardwaj, N; Spira, J; Christos, P; Nanus, D; Polsky, D; Osman, I
2006 JAN ;19(4):89A-89A, Modern pathology
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Neutral endopeptidase (NEP) overexpression is associated with progression in malignant melanoma (MM)and is a potential target of treatment
Velazquez, EF; Yancovitz, M; Sorhaindo, L; Bogunovic, D; O'Neill, D; Shapiro, R; Pavlick, A; Berman, R; Bhardwaj, N; Spira, J; Christos, P; Nanus, D; Polsky, D; Osman, I
2006 JAN ;86(4):89A-89A, Laboratory investigation
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Clinical relevance of neutral endopeptidase overexpression in melanoma
Yancovitz, M; Velazquez, E; Christos, P; Pavlick, A; Berman, R; Shapiro, R; Bhardwaj, N; Nanus, D; Polsky, D; Osman, I
2006 JUN 20 ;24(18):459S-459S, Journal of clinical oncology
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Association of melanoma and neurocutaneous melanocytosis with large congenital melanocytic naevi-results from the NYU-LCMN registry
Hale, E K; Stein, J; Ben-Porat, L; Panageas, K S; Eichenbaum, M S; Marghoob, A A; Osman, I; Kopf, A W; Polsky, D
2005 Mar;152(3):512-517, British journal of dermatology
— id: 49368, year: 2005, vol: 152, page: 512, stat: Journal Article,

PTEN expression in melanoma: relationship with patient survival, Bcl-2 expression, and proliferation
Mikhail, Maryann; Velazquez, Elsa; Shapiro, Richard; Berman, Russell; Pavlick, Anna; Sorhaindo, Lian; Spira, Joanna; Mir, Carmen; Panageas, Katherine S; Polsky, David; Osman, Iman
2005 Jul 15;11(14):5153-5157, Clinical cancer research
— id: 57826, year: 2005, vol: 11, page: 5153, stat: Journal Article,

Novel human cancer biomarkers identified by blood cells gene expression
Osman, I; Bajorin, D; Sun, TT; Mikhail, M; Zhong, H; Zheng, R; Han, M; Marshall, W; Liew, CC
2005 JUN 1 ;23(16):385S-385S, Journal of clinical oncology
— id: 57797, year: 2005, vol: 23, page: 385S, stat: Journal Article,

Serum levels of shed Her2/neu protein in men with prostate cancer correlate with disease progression
Osman, Iman; Mikhail, Maryann; Shuch, Brian; Clute, Megan; Cheli, Carol D; Ghani, Farooq; Thiel, Robert P; Taneja, Samir S
2005 Dec;174(6):2174-2177, Journal of urology
— id: 68182, year: 2005, vol: 174, page: 2174, stat: Journal Article,

Early diagnosis of cutaneous melanoma: revisiting the ABCD criteria
Abbasi, Naheed R; Shaw, Helen M; Rigel, Darrell S; Friedman, Robert J; McCarthy, William H; Osman, Iman; Kopf, Alfred W; Polsky, David
2004 Dec 8;292(22):2771-2776, JAMA
— id: 47818, year: 2004, vol: 292, page: 2771, stat: Journal Article,

Altered N-myc downstream-regulated gene 1 protein expression in African-American compared with caucasian prostate cancer patients
Caruso, Robert P; Levinson, Benjamin; Melamed, Jonathan; Wieczorek, Rosemary; Taneja, Samir; Polsky, David; Chang, Caroline; Zeleniuch-Jacquotte, Anne; Salnikow, Konstantin; Yee, Herman; Costa, Max; Osman, Iman
2004 Jan 1;10(1 Pt 1):222-227, Clinical cancer research
— id: 44771, year: 2004, vol: 10, page: 222, stat: Journal Article,

Clinical significance of BRAF mutations in metastatic melanoma
Chang DZ; Panageas KS; Osman I; Polsky D; Busam K; Chapman PB
2004 Dec 21;2(1):46-46, Journal of translational medicine
— id: 57827, year: 2004, vol: 2, page: 46, stat: Journal Article,

Tissue microarrays, tread carefully
Chiriboga, Luis; Osman, Iman; Mikhail, Maryann; Lau, Christie
2004 Dec;84(12):1677-1677, Laboratory investigation
— id: 57828, year: 2004, vol: 84, page: 1677, stat: Journal Article,

Racial disparity of epidermal growth factor receptor (EGFR) expression in prostate cancer (PC)
Osman, I; Shuch, B; Yee, H; Lee, P; Cordon-Crado, C; Taneja, S; Chang, C; Satagopan, J
2004 JUL 15 ;22(14):395S-395S, Journal of clinical oncology
— id: 48683, year: 2004, vol: 22, page: 395S, stat: Journal Article,

Detection of circulating cancer cells expressing uroplakins and epidermal growth factor receptor in bladder cancer patients
Osman, Iman; Kang, Melissa; Lee, Andy; Deng, Fang-Ming; Polsky, David; Mikhail, Maryann; Chang, Caroline; David, Dexter A; Mitra, Nandita; Wu, Xue-Ru; Sun, Tung-Tien; Bajorin, Dean F
2004 Oct 10;111(6):934-939, International journal of cancer
— id: 44185, year: 2004, vol: 111, page: 934, stat: Journal Article,

Neutral endopeptidase protein expression and prognosis in localized prostate cancer
Osman, Iman; Yee, Herman; Taneja, Samir S; Levinson, Benjamin; Zeleniuch-Jacquotte, Anne; Chang, Caroline; Nobert, Craig; Nanus, David M
2004 Jun 15;10(12 Pt 1):4096-4100, Clinical cancer research
— id: 44832, year: 2004, vol: 10, page: 4096, stat: Journal Article,

Frequent alteration of the p161NK4A tumor suppressor gene by deletion, promotoer methylation, and point mutation in human melanoma metastases
Polsky, D; Freedberg, D; Russak, J; Kaplow, M; Busam, K; Osman, I
2004 MAR ;122(3):A159-A159, Journal of investigative dermatology
— id: 46586, year: 2004, vol: 122, page: A159, stat: Journal Article,

Racial disparity of epidermal growth factor receptor expression in prostate cancer
Shuch, Brian; Mikhail, Maryann; Satagopan, Jaya; Lee, Peng; Yee, Herman; Chang, Caroline; Cordon-Cardo, Carlos; Taneja, Samir S; Osman, Iman
2004 Dec 1;22(23):4725-4729, Journal of clinical oncology
— id: 46900, year: 2004, vol: 22, page: 4725, stat: Journal Article,

Altered expression of p27 and Skp2 proteins in prostate cancer of African-American patients
Drobnjak, Marija; Melamed, Jonathan; Taneja, Samir; Melzer, Kate; Wieczorek, Rosemary; Levinson, Benjamin; Zeleniuch-Jacquotte, Anne; Polsky, David; Ferrara, Jay; Perez-Soler, Roman; Cordon-Cardo, Carlos; Pagano, Michele; Osman, Iman
2003 Jul;9(7):2613-2619, Clinical cancer research
— id: 38153, year: 2003, vol: 9, page: 2613, stat: Journal Article,

Analysis of BRAF and N-RAS mutations in metastatic melanoma tissues
Gorden, Alexis; Osman, Iman; Gai, Weiming; He, Dan; Huang, Weiqing; Davidson, Anne; Houghton, Alan N; Busam, Klaus; Polsky, David
2003 Jul 15;63(14):3955-3957, Cancer research
— id: 38152, year: 2003, vol: 63, page: 3955, stat: Journal Article,

Evaluation of the proliferation marker MIB-1 in the prognosis of cutaneous malignant melanoma
Hazan, Carole; Melzer, Kate; Panageas, Katherine S; Li, Eric; Kamino, Hideko; Kopf, Alfred; Cordon-Cardo, Carlos; Osman, Iman; Polsky, David
2002 Aug 1;95(3):634-640, Cancer
— id: 39596, year: 2002, vol: 95, page: 634, stat: Journal Article,

Fluorinated deoxyglucose positron emission tomography imaging in progressive metastatic prostate cancer
Morris, Michael J; Akhurst, Timothy; Osman, Iman; Nunez, Rodolfo; Macapinlac, Homer; Siedlecki, Karen; Verbel, David; Schwartz, Lawrence; Larson, Steven M; Scher, Howard I
2002 Jun;59(6):913-918, Urology
— id: 38438, year: 2002, vol: 59, page: 913, stat: Journal Article,

HER-2 profiling and targeting in prostate carcinoma
Morris, Michael J; Reuter, Victor E; Kelly, W Kevin; Slovin, Susan F; Kenneson, Kate; Verbel, David; Osman, Iman; Scher, Howard I
2002 Feb 15;94(4):980-986, Cancer
— id: 68527, year: 2002, vol: 94, page: 980, stat: Journal Article,

Combined 18F-FDG and 11C-methionine PET scans in patients with newly progressive metastatic prostate cancer
Nunez, Rodolfo; Macapinlac, Homer A; Yeung, Henry W D; Akhurst, Tim; Cai, Shangde; Osman, Iman; Gonen, Mithat; Riedel, Elyn; Scher, Howard I; Larson, Steven M
2002 Jan;43(1):46-55, Journal of nuclear medicine
— id: 38439, year: 2002, vol: 43, page: 46, stat: Journal Article,

Alteration of p53 pathway in squamous cell carcinoma of the head and neck: impact on treatment outcome in patients treated with larynx preservation intent
Osman, Iman; Sherman, Eric; Singh, Bhuvanesh; Venkatraman, Ennapadam; Zelefsky, Michael; Bosl, George; Scher, Howard; Shah, Jatin; Shaha, Ashok; Kraus, Dennis; Cordon-Cardo, Carlos; Pfister, David G
2002 Jul 1;20(13):2980-2987, Journal of clinical oncology
— id: 38136, year: 2002, vol: 20, page: 2980, stat: Journal Article,

HDM2 protein overexpression and prognosis in primary malignant melanoma
Polsky, David; Melzer, Kate; Hazan, Carole; Panageas, Katherine S; Busam, Klaus; Drobnjak, Maria; Kamino, Hideko; Spira, Joanna G; Kopf, Alfred W; Houghton, Alan; Cordon-Cardo, Carlos; Osman, Iman
2002 Dec 4;94(23):1803-1806, Journal of the National Cancer Institute
— id: 39357, year: 2002, vol: 94, page: 1803, stat: Journal Article,

HER-2/neu (p185neu) protein expression in the natural or treated history of prostate cancer
Osman I; Scher HI; Drobnjak M; Verbel D; Morris M; Agus D; Ross JS; Cordon-Cardo C
2001 Sep;7(9):2643-2647, Clinical cancer research
— id: 38137, year: 2001, vol: 7, page: 2643, stat: Journal Article,

HDM2 protein overexpression: a potential target of treatment of cutaneous melanoma
Osman, I; Polsky, D; Melzer, K; Hazan, C; Cordon-Cardo, C; Houghton, A; Busam, K; Bastian, B
2001 NOV ;7(11):3790S-3790S, Clinical cancer research
— id: 54801, year: 2001, vol: 7, page: 3790S, stat: Journal Article,

HDM2 protein overexpression, but not gene amplification, is related to tumorigenesis of cutaneous melanoma
Polsky D; Bastian BC; Hazan C; Melzer K; Pack J; Houghton A; Busam K; Cordon-Cardo C; Osman I
2001 Oct 15;61(20):7642-7646, Cancer research
— id: 26597, year: 2001, vol: 61, page: 7642, stat: Journal Article,

Overexpression of cyclin D1 is associated with metastatic prostate cancer to bone
Drobnjak M; Osman I; Scher HI; Fazzari M; Cordon-Cardo C
2000 May;6(5):1891-1895, Clinical cancer research
— id: 38138, year: 2000, vol: 6, page: 1891, stat: Journal Article,

The development of biologic end points in patients treated with differentiation agents: an experience of retinoids in prostate cancer
Kelly WK; Osman I; Reuter VE; Curley T; Heston WD; Nanus DM; Scher HI
2000 Mar;6(3):838-846, Clinical cancer research
— id: 38139, year: 2000, vol: 6, page: 838, stat: Journal Article,

Detection of prostatic specific membrane antigen messenger RNA using immunobead reverse transcriptase polymerase chain reaction
Ghossein RA; Osman I; Bhattacharya S; Ferrara J; Fazzari M; Cordon-Cardo C; Scher HI
1999 Jun;8(2):59-65, Diagnostic molecular pathology
— id: 38140, year: 1999, vol: 8, page: 59, stat: Journal Article,

Overexpression of the cyclin-dependent kinase inhibitor p16 is associated with tumor recurrence in human prostate cancer
Lee CT; Capodieci P; Osman I; Fazzari M; Ferrara J; Scher HI; Cordon-Cardo C
1999 May;5(5):977-983, Clinical cancer research
— id: 38142, year: 1999, vol: 5, page: 977, stat: Journal Article,

Differential Metabolism and Pharmacokinetics of L-[1-(11)C]-Methionine and 2-[(18)F] Fluoro-2-deoxy-D-glucose (FDG) in Androgen Independent Prostate Cancer
Macapinlac HA; Humm JL; Akhurst T; Osman I; Pentlow K; Shangde C; Yeung HW; Squire O; Finn RD; Scher HI; Larson SM
1999 May;2(3):173-181, Clinical positron imaging
— id: 38130, year: 1999, vol: 2, page: 173, stat: Journal Article,

Inactivation of the p53 pathway in prostate cancer: impact on tumor progression
Osman I; Drobnjak M; Fazzari M; Ferrara J; Scher HI; Cordon-Cardo C
1999 Aug;5(8):2082-2088, Clinical cancer research
— id: 38141, year: 1999, vol: 5, page: 2082, stat: Journal Article,

Distinct altered patterns of p27KIP1 gene expression in benign prostatic hyperplasia and prostatic carcinoma
Cordon-Cardo C; Koff A; Drobnjak M; Capodieci P; Osman I; Millard SS; Gaudin PB; Fazzari M; Zhang ZF; Massague J; Scher HI
1998 Sep 2;90(17):1284-1291, Journal of the National Cancer Institute
— id: 38145, year: 1998, vol: 90, page: 1284, stat: Journal Article,

Uroplakin II gene is expressed in transitional cell carcinoma but not in bilharzial bladder squamous cell carcinoma: alternative pathways of bladder epithelial differentiation and tumor formation [published erratum appears in Cancer Res 1998 Jul 1;58(13):2904]
Wu RL; Osman I; Wu XR; Lu ML; Zhang ZF; Liang FX; Hamza R; Scher H; Cordon-Cardo C; Sun TT
1998 Mar 15;58(6):1291-1297, Cancer research
— id: 7863, year: 1998, vol: 58, page: 1291, stat: Journal Article,

Chromosome 16 in primary prostate cancer: a microsatellite analysis
Osman I; Scher H; Dalbagni G; Reuter V; Zhang ZF; Cordon-Cardo C
1997 May 16;71(4):580-584, International journal of cancer
— id: 38146, year: 1997, vol: 71, page: 580, stat: Journal Article,

Expression of cyclin D1, but not cyclins E and A, is related to progression in bilharzial bladder cancer
Osman I; Scher H; Zhang ZF; Soos TJ; Hamza R; Eissa S; Khaled H; Koff A; Cordon-Cardo C
1997 Dec;3(12 Pt 1):2247-2251, Clinical cancer research
— id: 38144, year: 1997, vol: 3, page: 2247, stat: Journal Article,

Alterations affecting the p53 control pathway in bilharzial-related bladder cancer
Osman I; Scher HI; Zhang ZF; Pellicer I; Hamza R; Eissa S; Khaled H; Cordon-Cardo C
1997 Apr;3(4):531-536, Clinical cancer research
— id: 38143, year: 1997, vol: 3, page: 531, stat: Journal Article,

A randomized study of recombinant colony stimulating factor as adjuvant to induction treatment of aggressive non-Hodgkin lymphoma
Osman I; Hamza R; El-Khodary A; Khaled H; Gaafer R; El-Zawahry H
1994 ;7:115-122, Journal of the Egyptian National Cancer Institute
— id: 38148, year: 1994, vol: 7, page: 115, stat: Journal Article,

The efficacy and tolerability of tropistron in the prevention of chemotherapy induced emesis
Osman I; Hamza R; El-Khodary A; Khaled H; Gaafer R; Kamel H; El-Zawahry H
1993 ;6:249-254, Journal of the Egyptian National Cancer Institute
— id: 38147, year: 1993, vol: 6, page: 249, stat: Journal Article,