Victoria M Harnik, Ph.D.

Elsevier's integrated anatomy and embryology
Bogart, Bruce Ian; Ort, Victoria H
Philadelphia : Mosby/Elsevier, 2007,
— id: 1386, year: 2007, vol: , page: , stat: ,

A review of clinically relevant human anatomy in emergency medicine
Campanella, Lisa Marie; Bloch, Helen; Gang, Maureen; Rennie, William; Ort, Victoria
2005 Oct;29(3):347-352, Journal of emergency medicine
The objectives of this project were to establish a practical model for the review of clinical anatomy relevant to the assessment and care of the ill and injured patient, and to design practice models for invasive procedures using human cadaver, porcine cadaver, and plastic model material. A practical course based on the human gross anatomy of the face, neck, thorax, airway, arm, and leg was designed. Regional anesthesia techniques, arthrocentesis, saphenous vein cutdown, central venous and arterial cannulation, surgical airway, thoracostomy tube placement and thoracotomy were integrated into the appropriate practice stations. A syllabus was developed. A clinically relevant, online anatomy atlas demonstrating all of the above was developed. In conclusion, an anatomy review course combining clinically relevant, human, gross anatomy and procedure practice stations was established
— id: 72057, year: 2005, vol: 29, page: 347, stat: Journal Article,

The use of a dissected bovine heart to teach cardiac sonography
Campanella, Lisa Marie; Pancu, Diana; Gang, Maureen; Marill, Keith A; Ort, Victoria
2004 Aug;11(7):782-785, Academic emergency medicine
OBJECTIVES: To create and test a dissected bovine heart model (BHM) to facilitate the interpretation of cardiac sonography (CS). METHODS: After a pretest and an instructional video on CS, emergency physicians (EPs) were randomized into two groups. Group 1 viewed two-dimensional (2D) anatomic pictures of human hearts. Group 2 examined the BHM and the same anatomic pictures as group 1. The EPs retook the pretest. The differences between the raw pretest and posttest scores of the groups were compared with an unpaired Student's t-test. Multiple linear regression was used to adjust for confounding by variation in education and initial test scores. EPs with previous experience in CS were excluded from the analysis. RESULTS: Thirty-five participants met the inclusion criteria, 16 in group 1 and 19 in group 2. The groups were well balanced with respect to postgraduate year training. The EPs in group 1 had a higher average pretest score of 11.6 versus 8.1 in group 2. Compared with the pretest scores, the average improvements in group 1 and group 2 were 7.6 and 11.3 points, respectively. Group 2 improved an average of 3.7 points (95% confidence interval [95% CI] = 0.7 to 6.7; p = 0.016) more than group 1. After adjusting for confounding by the difference in initial scores, group 2 improved 1.8 (95% CI = -1.1 to 4.8; p = 0.22) more points on average than group 1. CONCLUSIONS: A dissected bovine heart model did not significantly improve the ability of EPs to label structures on static ultrasounds over inspection of static-labeled anatomic pictures alone
— id: 46123, year: 2004, vol: 11, page: 782, stat: Journal Article,

ISOLATION AND CHARACTERIZATION OF CDNA CLONES FOR RIBOPHORIN-I - COMPLETE CODING SEQUENCE AND INVITRO SYNTHESIS AND INSERTION OF THE ENCODING PRODUCT INTO ER MEMBRANES
ORT, V; PRAKASH, K; COLMAN, DR; ROSENFELD, MG; ADESNIK, M; SABATINI, DD; KREIBICH, G
1986 NOV ;103(5):A65-A65, Journal of cell biology
— id: 41317, year: 1986, vol: 103, page: A65, stat: Journal Article,

Biosynthesis and processing of ribophorins in the endoplasmic reticulum
Rosenfeld MG; Marcantonio EE; Hakimi J; Ort VM; Atkinson PH; Sabatini D; Kreibich G
1984 Sep;99(3):1076-1082, Journal of cell biology
Ribophorins are two transmembrane glycoproteins characteristic of the rough endoplasmic reticulum, which are thought to be involved in the binding of ribosomes. Their biosynthesis was studied in vivo using lines of cultured rat hepatocytes (clone 9) and pituitary cells (GH 3.1) and in cell-free synthesis experiments. In vitro translation of mRNA extracted from free and bound polysomes of clone 9 cells demonstrated that ribophorins are made exclusively on bound polysomes. The primary translation products of ribophorin messengers obtained from cultured hepatocytes or from regenerating livers co-migrated with the respective mature proteins, but had slightly higher apparent molecular weights (2,000) than the unglycosylated forms immunoprecipitated from cells treated with tunicamycin. This indicates that ribophorins, in contrast to all other endoplasmic reticulum membrane proteins previously studied, contain transient amino-terminal insertion signals which are removed co-translationally. Kinetic and pulse-chase experiments with [35S]methionine and [3H]mannose demonstrated that ribophorins are not subjected to electrophoretically detectable posttranslational modifications, such as proteolytic cleavage or trimming and terminal glycosylation of oligosaccharide side chain(s). Direct analysis of the oligosaccharides of ribophorin l showed that they do not contain the terminal sugars characteristic of complex oligosaccharides and that they range in composition from Man8GlcNAc to Man5GlcNAc. These findings, as well as the observation that the mature proteins are sensitive to endoglycosidase H and insensitive to endoglycosidase D, are consistent with the notion that the biosynthetic pathway of the ribophorins does not require a stage of passage through the Golgi apparatus
— id: 18428, year: 1984, vol: 99, page: 1076, stat: Journal Article,