Dmitry Novikov

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Dmitry Novikov

Associate Professor, Department of Radiology

Contact Info

Address
660 First Avenue
New York, NY 10016

212/263-2718
Dmitry.Novikov@nyumc.org


Research Summary

I bring the wealth of modern analytical tools from theoretical physics in order to quantify and interpret a variety of MRI modalities in terms of tissue structure below the nominal imaging resolution. I focus on MRI measurements of diffusion, transverse relaxation and perfusion, in order to quantify biophysical parameters such as cell structure and size, membrane permeability, amount of accumulated iron, etc, and to identify quantitative disease biomarkers in neurodegenerative diseases, tumors and myopathies. 

Research Keywords

mapping of tissue microstructure using diffusion and transverse relaxation MRI combined with biophysical modeling, imaging

In vivo observation and biophysical interpretation of time-dependent diffusion in human white matter
Fieremans, Els; Burcaw, Lauren M; Lee, Hong-Hsi; Lemberskiy, Gregory; Veraart, Jelle; Novikov, Dmitry S. In vivo observation and biophysical interpretation of time-dependent diffusion in human white matter. Neuroimage. 2016 Jan 20;129:414-427 (1929552)

In vivo measurement of membrane permeability and myofiber size in human muscle using time-dependent diffusion tensor imaging and the random permeable barrier model
Fieremans, Els; Lemberskiy, Gregory; Veraart, Jelle; Sigmund, Eric E; Gyftopoulos, Soterios; Novikov, Dmitry S. In vivo measurement of membrane permeability and myofiber size in human muscle using time-dependent diffusion tensor imaging and the random permeable barrier model. NMR in biomedicine. 2016 Oct 7;:?-? (2274332)

In vivo quantification of demyelination and recovery using compartment-specific diffusion MRI metrics validated by electron microscopy
Jelescu, Ileana O; Zurek, Magdalena; Winters, Kerryanne V; Veraart, Jelle; Rajaratnam, Anjali; Kim, Nathanael S; Babb, James S; Shepherd, Timothy M; Novikov, Dmitry S; Kim, Sungheon G; Fieremans, Els. In vivo quantification of demyelination and recovery using compartment-specific diffusion MRI metrics validated by electron microscopy. Neuroimage. 2016 Feb 11;132:104-114 (1949552)

Optimal target VOI size for accurate 4D coregistration of DCE-MRI
Park, Brian; Mikheev, Artem; Wadghiri, Youssef Zaim; Bertrand, Anne; Novikov, Dmitry; Chandarana, Hersh; Rusinek, Henry. Optimal target VOI size for accurate 4D coregistration of DCE-MRI [Meeting Abstract]. Proceedings of SPIE (The International Society for Optical Engineering). 2016 ;9788:?-? (2228152)

Pulsed and oscillating gradient MRI for assessment of cell size and extracellular space (POMACE) in mouse gliomas
Reynaud, Olivier; Winters, Kerryanne Veronica; Hoang, Dung Minh; Wadghiri, Youssef Zaim; Novikov, Dmitry S; Kim, Sungheon Gene. Pulsed and oscillating gradient MRI for assessment of cell size and extracellular space (POMACE) in mouse gliomas. NMR in biomedicine. 2016 Oct;29(10):1350-1363 (2261502)