Richard I. Levin

Biosketch / Results /

Richard I. Levin, M.D.

Adjunct Professor; Professor Emeritus of Medicine;
Department of Medicine (Cardio Div)

Contact Info

Address
619 Palisade Avenue
The Arnold P. Gold Foundation
Englewood Cliffs, NJ 07632

Richard.Levin@nyumc.org

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Education

1974 — NYU, Medical Education
1975-1978 — NYU Medical Center (Medicine), Residency
1978-1980 — NYU Medical Center (Cardiology), Clinical Fellowships
1979-1983 — Cornell University Medical College (Cell Biology), PostDoctoral Training

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Research Summary

The NYU School of Medicine's Laboratory for Cardiovascular Research in the Department of Medicine uses a multidisciplinary approach to study atherosclerosis from bench to bedside. We focus on the effects of atherogenic biomolecules which modify endothelial function in leukocyte-endothelial interaction, thombosis and fibrinolysis, and endothelial proliferation.

The most compelling theory on the origins of atherosclerosis proposes that atherosclerosis is secondary to endothelial dysfunction or denuding endothelial injury. The mass of atherosclerosis, in turn, is proportional to both the magnitude and persistence of endothelial injury such that factors which delay reendothelialization enhance atherosclerosis. While atherosclerosis accelerates in patients with chronic renal failure (CRF) who are maintained on dialysis, the causes for this acceleration are unknown. We discovered that uremic levels of the end-metabolite oxalic acid dramatically inhibit the proliferation and migration of human endothelial cells (EC) in vitro. Oxalate inhibits endothelial regeneration and is, therefore, a candidate atherogenic toxin. Our recent work links these phenomena to an elevation in intracellular calcium [Ca++]i unique to EC. While it is clear that [Ca++]i is modulated during the cell cycle, it is not clear whether this modulation is both necessary and sufficient for progression through the cell cycle. Thus, the role of [Ca++]i as an oxalate-dependent moderator of EC proliferation is unknown. We are exploring the precise molecular mechanisms by which oxalate increases [Ca++]i, thereby inhibiting reedothelialization and promoting atherogenesis.

Research Interests

Endothelial Modulation of Atherosclerosis

Research Keywords

activators, atherosclerosis, calcium, cell proliferation, endothelium, plasminogen

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All data from NYU Health Sciences Library Faculty Bibliography — -

Contact:
http://hsl.med.nyu.edu/faculty-bibliography-search

Gazing through the crystal ball of science-cardiovascular disease in 2100
Fishman, G I; Levin, R I
2012 2012;9(2):86-89, US Cardiology
— id: 287912, year: 2012, vol: 9, page: 86, stat: Journal Article,

Publishing in the age of the digital doctor
Levin, R I
2011 Jan;18(1):11-12, Current oncology (Toronto, Ont.)
— id: 124100, year: 2011, vol: 18, page: 11, stat: Journal Article,

The power of Pasteur's quadrant: cardiovascular disease at the turn of the century
Levin, Richard I; Fishman, Glenn I
2011 Jun;25(6):1788-1792, FASEB journal
— id: 134174, year: 2011, vol: 25, page: 1788, stat: Journal Article,

Internal medicine residency training in the 21st century: aligning requirements with professional needs
Charap, Mitchell H; Levin, Richard I; Pearlman, R Ellen; Blaser, Martin J
2005 Sep;118(9):1042-1046, American journal of medicine
— id: 58700, year: 2005, vol: 118, page: 1042, stat: Journal Article,

The puzzle of aspirin and sex
Levin, RI
2005 MAR 31 ;352(13):1366-1368, New England journal of medicine
— id: 50417, year: 2005, vol: 352, page: 1366, stat: Journal Article,

Theriac found? Nitric oxide-aspirin and the search for the universal cure
Levin, Richard I
2004 Aug;44(3):642-643, Journal of the American College of Cardiology
— id: 648212, year: 2004, vol: 44, page: 642, stat: Journal Article,

Coronary artery disease and opioid use
Marmor, Michael; Penn, Arthur; Widmer, Kyle; Levin, Richard I; Maslansky, Robert
2004 Jun 15;93(10):1295-1297, American journal of cardiology
— id: 46186, year: 2004, vol: 93, page: 1295, stat: Journal Article,

Oxalic acid alters intracellular calcium in endothelial cells
Recht, Phoebe A; Tepedino, Gerard J; Siecke, Neil W; Buckley, Michael T; Mandeville, John T; Maxfield, Frederick R; Levin, Richard I
2004 May;173(2):321-328, Atherosclerosis
— id: 46112, year: 2004, vol: 173, page: 321, stat: Journal Article,

Surgical interactive multimedia modules: A novel, non-browser based architecture for medical education
Triola, MM; Holloway, W; Hopkins, MA; Levin, RI; Weiner, MJ; Riles, TS; Nachbar, MS
2004 ;17:423-427, Proceedings (IEEE Engineering in Medicine & Biology Society)
— id: 648902, year: 2004, vol: 17, page: 423, stat: Journal Article,

Medical humanities at New York University School of Medicine: an array of rich programs in diverse settings
Krackov, Sharon K; Levin, Richard I; Catanese, Veronica; Rey, Mariano; Aull, Felice; Blagev, Denitza; Dreyer, Benard; Grieco, Anthony J; Hebert, Cristy; Kalet, Adina; Lipkin, Mack Jr; Lowenstein, Jerome; Ofri, Danielle; Stevens, David
2003 Oct;78(10):977-982, Academic medicine
— id: 39038, year: 2003, vol: 78, page: 977, stat: Journal Article,

Ruptured plaques and leaking cells: cost-effectiveness in the diagnosis of acute coronary syndromes
Fox AC; Levin RI
1999 Dec 21;131(12):968-970, Annals of internal medicine
— id: 8579, year: 1999, vol: 131, page: 968, stat: Journal Article,

Natriuretic peptides: physiology, therapeutic potential, and risk stratification in ischemic heart disease
Stein BC; Levin RI
1998 May;135(5 Pt 1):914-923, American heart journal
— id: 7806, year: 1998, vol: 135, page: 914, stat: Journal Article,

Randomised double-blind trial of fixed low-dose warfarin with aspirin after myocardial infarction
Fuster V; Califf RM; Chesebro JH; Cohen M; Comp PC; Gheorghiade M; Hall J; Halperin J; Khan S; Kopecky S; Langer A; Molk B; Moss A; OConnor CM; OGara PT; Raskob E; Sutton J; Braunwald E; Bell WR; Furberg C; Rapaport E; DeMets D; Goldstein S; Richardson D; Hillis D; Bonow R; Kistler JP; Mohr JP; Sherman D; Fisher M; Feyzi J; Cook T; Califf RM; Harrington RA; Berkowitz SD; Jett L; Berdan L; McDougal M; Friedman E; Daniel J; Roncskevitz E; Hwang S; Crowell D; Paganini M; Andahl L; OConnor C; Lucas K; Collins GJ; Mark RJ; Siegel RM; Koehnemann G; Greer S; Schweitzer AC; Lawrence JE; Allen SM; Wiseman AH; Warwick DJ; Bennett WT; Simmons K; Sheikh KH; Hengerer T; Campbell PT; Patterson JT; Bates M; Mathews A; Roark SF; Marquis N; Goldner DB; Brown G; Parker JP; Wells CB; McGrew FA; Hamilton B; Carney RJ; Crispin S; Cummins FE; Nonnweiler JM; Collins GV; Hathaway J; Conn E; McWilliams C; Geroge JM; Roncevich T; Reeves BR; Dinsmore N; Bender R; DeRosa K; OConnor CM; Hoffman S; Wertheimer J; Turner S; Crandall CW; Higgins DL; Berger BC; Palazzo D; Fontanet H; Ford E; Chu AA; Pierson M; Seaworth JF; Jensen J; Hoche JP; Ford EA; Goodfield P; Sprowls H; Schmidt PJ; Ness C; ODonnell G; McNamee S; Koren MJ; Baker J; Hassel CD; Hartley D; Unks M; Rodgers K; Muhlestein JB; Allen A; Sacchi TJ; Major A; Kmonicek JM; Shane JW; Goulah RD; Harner R; Bannon PJ; Heyl AE; Wall TC; Milks S; Ramo BW; Heimgartner K; Vranian RB; Louder DR; Stack RK; Jackson LL; Berman EJ; Hawkins D; Aycock GR; Wilcox T; West SR; Fowler P; Alagona P; Moore A; Hines J; Minor JR; Kereiakes DJ; Martin LH; Frid DJ; Homan JA; Burks JM; Kirby JC; Puma J; Jones L; Schneider RM; Lyttle B; Talley JD; Ashcraft S; Joseph A; CorumHartly J; McNeer JF; Laden DL; Belkin RN; Williamson J; Langer A; Hill C; Buttoo K; Kachra A; Langer G; Kavannaugh L; Shrives DM; Strauss H; Anderson P; Kwok K; Kern C; Cheung MT; Nawrocki H; Darcel IC; Ali N; Campbell D; Sluzar V; Hink H; Lam J; Marquis J; Parker JD; Wilson J; James R; Nolf B; Zawadowski A; Bhargava R; Gupta M; Sevitt B; Fitzsimons J; Burke BR; Chomyc R; Singh N; Bozek B; Roth SL; Smith J; Fell DA; Willoughy L; Ranganathan N; Nawrocki H; Langer A; Hill C; Morgan C; Balleza L; Sasson Z; Nolf B; LenkeiKerwin S; Wilson J; McAlister NH; Karhra N; Gangbar E; Willoughby L; Hess A; Gaudet M; Bhesania T; Burge D; OGara P; Haggan C; Gibson M; Slater A; Stone PH; Clemente C; Polansky BJ; Clements PJ; Schael F; McGough E; Daum RM; Carey G; Gillam LD; Hall DJ; Venditti FJ; Woodhead G; Birkhead RG; McConnell D; Jang IK; Haggan C; Sadaniantz A; Staples E; Weinshel AJ; Weinshel G; Cohen M; Sherwood J; Palabrica T; Brown AM; Hack TC; Pavao F; McKendall FR; Wheeler JL; Gaughan C; Medici SE; Losordo DW; Hallette N; Waldman H; Criasia M; Battle R; Rowen M; Klein ME; Hankin B; Radford MJ; Kearney L; Becker RC; Ball SP; Sharma GVRK; Lapsley DP; Watrous BG; Stanton A; Kopecky S; Holland A; Shelhamer L; Gudmonson K; Basu HN; Brickman D; Ramee SR; Landry KJ; Heltne CE; Bergal LA; Lyons RM; Bussey HI; Asinger R; Fifield JH; Bruns DL; Gadient L; Kincaid D; Berg S; Storvick E; Westphal D; Rezkalla SH; White E; Safford RE; Doucette K; Cookman JJ; Fangman L; Anderson BJ; Swan M; Kouba C; Theige T; Vacek JL; Nolte B; Hurley DV; Kaskie K; Gard JR; Harre SJ; Solberg L; Miller K; Miller RR; Rickards J; Yawn RA; Kurland M; Haugland JM; Slivken R; Hession WT; Strum S; Stowers SA; Abuan T; DeWood MA; Reinhardt S; Kopecky SL; Richardson D; Isele R; Block C; Swenson LJ; Vittum KA; Weeks G; Brennan M; Chapman D; ThomMorgan J; Chelliah N; Carter D; Friedman B; Haffey K; Webel R; Rood M; Andrews TC; July ME; Edin AE; Hester TS; Sutton J; McCollough T; Schulman D; Deloplaine K; Besley D; Dunn S; Richards F; Shipman D; Josephson RA; Jasso D; Fleischer L; Lofrano S; Spriggs D; Wahl S; Font VE; Trottier M; Sutton J; DeLuca SA; Schwarz EF; Beckham T; Mickolich JR; Snyder M; Langholz D; Johnson E; Beaver BB; Tedrick R; Boyd JJ; Probst P; Bear PA; Craig MB; Blumenthal RS; Carnes T; Villa AE; Atkins F; Storer WQ; Payne MA; ODonnell MJ; Prochnow L; Yakubov S; Noethen A; Gonzalez M; Jopperi E; Joyce D; Mishak S; Reen BM; Whisnant DR; Gacioch GM; Chiodo V; Effron MB; Utley K; Frank S; Dankoski C; Krauthamer D; Welcom GT; Aguirre FV; Stonner T; Cannon L; Harris M; Brown DL; MoeHufford K; Hattemer CR; Howard W; Gilmore PS; Wofford R; Bates ER; Alexandris C; McClure JM; Dinninger J; Molk B; Danhour G; Pacheco JP; Longo JA; Molk BL; Bickett K; Baum RS; Jenkins R; Brockington L; Harding C; Luckasen GJ; Rayder K; Ptasnik MJ; Harding C; Brachfeld CA; Vincze T; Cadigan RA; Wubbena BA; Smith BR; ONeill D; Pachelo GM; Godfrey CC; Fecik C; Larson D; Rayder K; Backup LD; Drake Z; Miklin JS; Aris G; Schwartz DJ; Stark S; Smith S; Eastburn T; Marsh R; Lorenz S; Thompson R; Kleinman J; Aris G; Breckinridge JC; Dauber IM; Bell W; VanBenthuysen K; Prevedel J; Fecik C; Stringer KA; Whiterock A; Levitt PW; Petras J; Cohen M; Stoakes K; Daniels S; Sternberg C; Mazuz M; Frymoyer BS; Dickstein RA; Banger D; Kramer JH; Evans C; Victor M; Luhmann S; Worley WJ; Tuzi J; Janzer SF; Lysgaard JK; Stillabower ME; DiSabatino A; Voyce S; Keating D; Cohen M; Stoakes K; Zakrzewski M; Hayes C; Owens JS; Amburg C; Zatuchni J; Boyle M; Gheorghiade M; Mistovich M; Zayac J; DeGirolami D; Peterson D; Glick G; Reda A; Hueter D; Weszt S; Wynne J; Ladd DF; Mathew J; Davidson S; Borzak S; Cruz TA; Chiu C; Sedlarz P; Shanes JG; Calkins M; Alexander J; Steckel L; McKierman TL; Galbraith E; Sorkin RP; Moxley B; Sagar KB; Mauermann SK; Fairbairn JP; Walczak D; Willis PW; Boichot H; Barr LA; Burns A; Fintel D; Feiereisel P; Tommaso C; McDermott EV; Rosenson RS; Spokas D; AlHani A; Andrade M; Schreiber TL; Trevino C; Meisenbach JA; Bigler P; Evans J; Arslanian C; Rich S; Genthner DE; Eisenberg P; Fasholz JE; Chua KG; Schneider JM; Timmis GC; Golias R; Jafri S; Flandorfer C; Halperin J; Rothlauf E; Forman R; Furia S; Bhalodkar NC; Valeria A; Miller DA; Silvasi D; DeLeon J; Quyyami B; Mueller HS; Cosico J; Vorchheimer D; Guzman IC; Levin RI; Mele KA; Morrison J; Ward M; Gregory J; Romano J; Macina G; Kikel M; Kwan T; Julien R; Zeldis SM; Bilodeau SE; Comp P; Gates JL; Sigal SL; Oyer LF; Moss A; Brown M; Braden GA; Wesley DJ; Gillespie JA; Cohen L; Krone RJ; Humphrey JR; Bodenheimer MM; Kelly N; Lichstein E; Budzilowicz L; VanVoorhees L; Silverman A; Arora R; Blowers A; Greenberg H; McAnulty M; Hochman J; Goldstein RE; Shapiro S; Marcus FI; Gear K; Hall J; Faussett D; Border JF; Dinehart A; Atassi K; Smith F; Hahn R; ViellieuFischer B; Graham JD; Cheng WM; Rink LD; Satterfield JL; Slack JD; Burkert M; Tavel ME; Childress S; Sadiq RM; Sands P; Jennings M; Freestone J; Hall JH; Linden P; Lapp M; Habig E; Shelburne S; Khan S; Gray R; Defensor L; Fleisher JH; Patterson JA; Russell V; Karlsberg RP; Maccioni S; Cercek B; Conte S; Sowka L; Torgerson M; Levy MC; Alejandro PM; Polito S; Roll K; French WJ; Terrell D; Shook TL; Junio LN; Swan DA; Ujiiye D; Mahrer P; Noceda J; Kaushik V; Mueco A; Wallis J; Abrahamson D; Seiler B; Merz RH; Martin D; Ladenheim M; LozykZehr GM; Brodsky M; Chaim S; Bersohn MM; Silbar C; Pandian MG; Eldridge P; Lob IK; Smith C
1997 ;350(9075):389-396, Lancet
— id: 130406, year: 1997, vol: 350, page: 389, stat: Journal Article,

Wound healing is accelerated by agonists of adenosine A2 (G alpha s-linked) receptors
Montesinos MC; Gadangi P; Longaker M; Sung J; Levine J; Nilsen D; Reibman J; Li M; Jiang CK; Hirschhorn R; Recht PA; Ostad E; Levin RI; Cronstein BN
1997 Nov 3;186(9):1615-1620, Journal of experimental medicine
— id: 7954, year: 1997, vol: 186, page: 1615, stat: Journal Article,

The complement activation product C5a stimulates endothelial expression of a novel adhesion protein
Cronstein, BN; Lozada, CM; Naime, D; Morabito, L; Montesinos, MC; Levin, RI
1996 SEP ;39(9):333-333, Arthritis & rheumatism
— id: 52779, year: 1996, vol: 39, page: 333, stat: Journal Article,

Adenosine A(2) receptor occupancy promotes fibroblast and endothelial cell migration and wound healing
Cronstein, BN; Montesinos, C; Gadangi, P; Longaker, M; Ostad, E; Recht, PA; Levin, RI
1996 MAR ;44(3):A226-A226, Journal of investigative medicine
— id: 52942, year: 1996, vol: 44, page: A226, stat: Journal Article,

Effects of amlodipine on glomerular filtration, growth, and injury in experimental hypertension
Dworkin, LD; Tolbert, E; Recht, PA; Hersch, JC; Feiner, H; Levin, RI
1996 FEB ;27(2):245-250, Hypertension
— id: 53069, year: 1996, vol: 27, page: 245, stat: Journal Article,

The anti-inflammatory mechanism of sulfasalazine is related to adenosine release at inflamed sites
Gadangi P; Longaker M; Naime D; Levin RI; Recht PA; Montesinos MC; Buckley MT; Carlin G; Cronstein BN
1996 Mar 1;156(5):1937-1941, Journal of immunology
— id: 9818, year: 1996, vol: 156, page: 1937, stat: Journal Article,

Accelerated atherosclerosis in South Asian expatriates living in New York
Kathuria, N; Koenig, K; Schwartzbard, A; Mele, KA; Levin, RI
1996 MAR ;44(3):A312-A312, Journal of investigative medicine
— id: 52967, year: 1996, vol: 44, page: A312, stat: Journal Article,

Vitamin B6 prevents the endothelial toxicity and rise in intracellular free calcium induced by uremic levels of oxalic acid
Levin, RI; Maxfield, FR; Recht, PA; Buckley, MT; Mandeville, JM
1996 OCT 15 ;94(8):1295-1295, Circulation
— id: 52744, year: 1996, vol: 94, page: 1295, stat: Journal Article,

Evidence for apoptosis in Alzheimer's disease
Marcus, DL; Thomas, CG; Levin, R; Golomb, J; Recht, P; Freedman, ML
1996 MAR ;44(3):A308-A308, Journal of investigative medicine
— id: 52966, year: 1996, vol: 44, page: A308, stat: Journal Article,

Adenosine A(2) receptor occupancy promotes fibroblast and endothelial cell migration and wound healing
Montesinos, MC; Gadangi, P; Longaker, M; Ostad, E; Recht, RA; Levin, RI; Cronstein, BN
1996 SEP ;39(9):1703-1703, Arthritis & rheumatism
— id: 52794, year: 1996, vol: 39, page: 1703, stat: Journal Article,

Preliminary report: double-blind, placebo-controlled study of fluoxetine in depressed alcoholics
Cornelius, J R; Salloum, I M; Cornelius, M D; Perel, J M; Ehler, J G; Jarrett, P J; Levin, R L; Black, A; Mann, J J
1995 ;31(2):297-303, Psychopharmacology bulletin
— id: 148634, year: 1995, vol: 31, page: 297, stat: Journal Article,

Colchicine alters the quantitative and qualitative display of selectins on endothelial cells and neutrophils
Cronstein BN; Molad Y; Reibman J; Balakhane E; Levin RI; Weissmann G
1995 Aug;96(2):994-1002, Journal of clinical investigation
— id: 56750, year: 1995, vol: 96, page: 994, stat: Journal Article,

Cardiologic evaluation
Levin RI; Kronzon I
Emergency diagnostic testing St. Louis MO : Mosby, 1995,
— id: 4552, year: 1995, vol: , page: 169, stat: Chapter,

SODIUM OXALATE, A SPECIFIC ENDOTHELIAL TOXIN OF UREMIA CHRONICALLY ELEVATES INTRACELLULAR CALCIUM ONLY IN ENDOTHELIAL-CELLS
LEVIN, RI; RECHT, PA; BUCKLEY, MT; MANDEVILLE, JTH; JAFFE, EA; MAXFIELD, FR
1995 OCT 15 ;92(8):767-767, Circulation
— id: 86675, year: 1995, vol: 92, page: 767, stat: Journal Article,

Identification of C1q as the heat-labile serum cofactor required for immune complexes to stimulate endothelial expression of the adhesion molecules E-selectin and intercellular and vascular cell adhesion molecules 1
Lozada C; Levin RI; Huie M; Hirschhorn R; Naime D; Whitlow M; Recht PA; Golden B; Cronstein BN
1995 Aug 29;92(18):8378-8382, Proceedings of the National Academy of Sciences of the United States of America
— id: 7927, year: 1995, vol: 92, page: 8378, stat: Journal Article,

Nonsteroidal antiinflammatory agents inhibit stimulated neutrophil adhesion to endothelium: adenosine dependent and independent mechanisms
Cronstein BN; Van de Stouwe M; Druska L; Levin RI; Weissmann G
1994 Jun;18(3):323-335, Inflammation
— id: 8416, year: 1994, vol: 18, page: 323, stat: Journal Article,

Nomenclature and criteria for diagnosis of diseases of the heart and great vessels, Criteria Committee of the New York Heart Association
[Dolgin M; Fox AC; Gorlin R; Levin RI; Devereaux RP; et al]
Boston : Little, Brown, 1994,
— id: 751, year: 1994, vol: , page: , stat: ,

Medical education database
Abramson, Steven; Levin, Richard I
[New York, NY : The School, 1993],
— id: 426, year: 1993, vol: , page: , stat: ,

Report of the Institutional self-study : subcommittee reports : prepared for the site visit of the Liaison Committee on Medical Education, March 1-4, 1993
Abramson, Steven; Levin, Richard I
[New York, NY : The School, 1993],
— id: 428, year: 1993, vol: , page: , stat: ,

Report of the Institutional self-study : summary : prepared for the site visit of the Liaison Committee on Medical Education, March 1-4, 1993
Abramson, Steven; Levin, Richard I
[New York, NY : The School, 1993],
— id: 427, year: 1993, vol: , page: , stat: ,

A NOVEL MODE OF ACTION FOR COLCHICINE - MODULATION OF ADHESION MOLECULES ON BOTH NEUTROPHILS AND ENDOTHELIUM
CRONSTEIN, BN; MOLAD, Y; REIBMAN, J; WEISSMANN, G; LEVIN, RI
1993 APR ;41(2):A138-A138, Clinical research
— id: 54258, year: 1993, vol: 41, page: A138, stat: Journal Article,

The cardiomyopathy of Duchenne's muscular dystrophy and the function of dystrophin
Cziner DG; Levin RI
1993 Mar;40(3):169-173, Medical hypotheses
— id: 13218, year: 1993, vol: 40, page: 169, stat: Journal Article,

Oxalate, a potential atherogenic toxin of uremia, inhibits endothelial cell proliferation induced by heparin-binding growth factors in vitro
Levin RI; Moscatelli DA; Recht PA
1993 ;1:179-192, Endothelium
— id: 27438, year: 1993, vol: 1, page: 179, stat: Journal Article,

INTERLEUKIN-1 (IL-1) INHIBITS THE MIGRATORY RESPONSE OF HUMAN UMBILICAL VEIN ENDOTHELIAL-CELLS (HUVEC) TO BASIC FIBROBLAST GROWTH-FACTOR (BFGF)
ODEKON, LE; ROGHANI, M; MOSCATELLI, DA; LEVIN, RI; RIFKIN, DB
1993 FEB 19 ;7(3):A193-A193, FASEB journal
— id: 54346, year: 1993, vol: 7, page: A193, stat: Journal Article,

A mechanism for the antiinflammatory effects of corticosteroids: the glucocorticoid receptor regulates leukocyte adhesion to endothelial cells and expression of endothelial-leukocyte adhesion molecule 1 and intercellular adhesion molecule 1
Cronstein BN; Kimmel SC; Levin RI; Martiniuk F; Weissmann G
1992 Nov 1;89(21):9991-9995, Proceedings of the National Academy of Sciences of the United States of America
— id: 9824, year: 1992, vol: 89, page: 9991, stat: Journal Article,

Corticosteroids are transcriptional regulators of acute inflammation
Cronstein BN; Kimmel SC; Levin RI; Martiniuk F; Weissmann G
1992 ;105:25-35, Transactions of the Association of American Physicians
— id: 9830, year: 1992, vol: 105, page: 25, stat: Journal Article,

Neutrophil adherence to endothelium is enhanced via adenosine A1 receptors and inhibited via adenosine A2 receptors
Cronstein BN; Levin RI; Philips M; Hirschhorn R; Abramson SB; Weissmann G
1992 Apr 1;148(7):2201-2206, Journal of immunology
— id: 9751, year: 1992, vol: 148, page: 2201, stat: Journal Article,

CORTICOSTEROIDS (CS) ARE TRANSCRIPTIONAL REGULATORS OF ACUTE-INFLAMMATION
CRONSTEIN, BN; KIMMEL, SC; MARTINIUK, F; LEVIN, RI; WEISSMANN, G
1992 APR ;40(2):A193-A193, Clinical research
— id: 51976, year: 1992, vol: 40, page: A193, stat: Journal Article,

OXALIC-ACID, A POTENTIAL ATHEROGENIC TOXIN OF UREMIA, ENTERS HUMAN ENDOTHELIAL-CELLS AND INHIBITS THE ENZYMES OF INTERMEDIARY METABOLISM
LEVIN, RI; RECHT, PA
1992 APR ;40(2):A226-A226, Clinical research
— id: 51983, year: 1992, vol: 40, page: A226, stat: Journal Article,

Methotrexate inhibits neutrophil function by stimulating adenosine release from connective tissue cells
Cronstein BN; Eberle MA; Gruber HE; Levin RI
1991 Mar 15;88(6):2441-2445, Proceedings of the National Academy of Sciences of the United States of America
— id: 8444, year: 1991, vol: 88, page: 2441, stat: Journal Article,

A NOVEL ANTIINFLAMMATORY ACTION OF METHOTREXATE (MTX) - MTX INCREASES ADENOSINE RELEASE FROM CONNECTIVE-TISSUE CELLS AND, THEREBY, INHIBITS NEUTROPHIL (PMN) FUNCTION
CRONSTEIN, BN; EBERLE, MA; GRUBER, H; LEVIN, RI
1991 MAR 11 ;5(4):A510-A510, FASEB journal
— id: 51703, year: 1991, vol: 5, page: A510, stat: Journal Article,

A FINAL COMMON PATHWAY FOR ANTIINFLAMMATORY AGENTS - INHIBITION OF LEUKOCYTE-ENDOTHELIAL INTERACTIONS
CRONSTEIN, BN; KIMMEL, SC; VANDESTOUWE, MJ; LEVIN, RI; WEISSMANN, G
1991 APR ;39(2):A285-A285, Clinical research
— id: 51614, year: 1991, vol: 39, page: A285, stat: Journal Article,

A final common pathway for anti-inflammatory agents: inhibition of leukocyte-endothelial interactions
Kimmel SC; van de Stouwe MJ; Levin RI; Weissmann G; Cronstein BN
1991 ;104:113-124, Transactions of the Association of American Physicians
— id: 9833, year: 1991, vol: 104, page: 113, stat: Journal Article,

THE OPPOSING EFFECTS OF ADENOSINE A1 AND A2 RECEPTOR OCCUPANCY ON STIMULATED NEUTROPHIL (PMN) ADHERENCE
Cronstein, BN; Levin, RI; Hirschhorn, R; Weissmann, G; Philips, MR; Abramson, SB
1990 Apr;38(2):A417-A417, Clinical research
— id: 31966, year: 1990, vol: 38, page: A417, stat: Journal Article,

Effects of nifedipine and enalapril on glomerular injury in rats with deoxycorticosterone-salt hypertension
Dworkin, L D; Levin, R I; Benstein, J A; Parker, M; Ullian, M E; Kim, Y; Feiner, H D
1990 Oct;259(4 Pt 2):F598-F604, American journal of physiology
— id: 74783, year: 1990, vol: 259, page: F598, stat: Journal Article,

STIMULATION OF ADENOSINE RELEASE FROM HUMAN ENDOTHELIAL-CELLS INHIBITS NEUTROPHIL FUNCTION
Levin, RI; Eberle, MA; Marchetta, P; Cronstein, BN
1990 Oct;82(4):177-177, Circulation
— id: 32039, year: 1990, vol: 82, page: 177, stat: Journal Article,

UREMIC LEVELS OF OXALIC-ACID SUPPRESS REPLICATION AND MIGRATION OF HUMAN ENDOTHELIAL-CELLS
Levin, RI; Kantoff, PW; Jaffe, EA
1990 Mar-Apr;10(2):198-207, Arteriosclerosis
— id: 31887, year: 1990, vol: 10, page: 198, stat: Journal Article,

Inhibition of tissue plasminogen activator activity by aspirin in vivo and its relationship to levels of tissue plasminogen activator inhibitor antigen, plasminogen activator and their complexes
Levin RI; Harpel PC; Harpel JG; Recht PA
1989 Oct;74(5):1635-1643, Blood
— id: 10486, year: 1989, vol: 74, page: 1635, stat: Journal Article,

CONTINUOUS ST SEGMENT ANALYSIS FOR THE DETECTION OF PERIOPERATIVE MYOCARDIAL ISCHEMIA
CLEMENTS, FM; MCCANN, RL; LEVIN, RI
1988 JUL ;16(7):710-711, Critical care medicine
— id: 41766, year: 1988, vol: 16, page: 710, stat: Journal Article,

Myocardial preservation during ischemia and reperfusion
Ip JH; Levin RI
1988 May;115(5):1094-1104, American heart journal
— id: 11112, year: 1988, vol: 115, page: 1094, stat: Journal Article,

COCAINE ALTERS PLATELET AND ENDOTHELIAL-CELL EICOSANOID SYNTHESIS
KRAMER, JL; SILVERS, AR; RECHT, PA; LOVENVIRTH, W; BELANOFF, J; WEISSMANN, G; LEVIN, RI
1988 APR ;36(3):A365-A365, Clinical research
— id: 41786, year: 1988, vol: 36, page: A365, stat: Journal Article,

Quantitation of transient myocardial ischemia by digital, ambulatory electrocardiography
Levin RI
1988 Jan 29;61(3):13B-17B, American journal of cardiology
— id: 11204, year: 1988, vol: 61, page: 13B, stat: Journal Article,

The effect of aspirin on the hemodynamic response to nitroglycerin
Levin RI; Feit F
1988 Jul;116(1 Pt 1):77-84, American heart journal
— id: 11051, year: 1988, vol: 116, page: 77, stat: Journal Article,

SODIUM OXALATE, A UREMIC TOXIN, INHIBITS ENDOTHELIAL-CELL GROWTH BY INHIBITING PROTEIN-SYNTHESIS
Belanoff, J; Levin, RI
1987 Sep;35(5):A785-A785, Clinical research
— id: 31353, year: 1987, vol: 35, page: A785, stat: Journal Article,

ENGAGEMENT OF ADENOSINE A2 RECEPTORS ENHANCES NEUTROPHIL CHEMOTAXIS WHILE INHIBITING THEIR STICKING TO ENDOTHELIUM
Cronstein, BN; Rose, FR; Levin, RI; Recht, PA; Hirschhorn, R; Weissmann, G
1987 Apr;35(3):A597-A597, Clinical research
— id: 31198, year: 1987, vol: 35, page: A597, stat: Journal Article,

NEUTROPHILS DIMINISH THE CONCENTRATION OF TISSUE PLASMINOGEN- ACTIVATOR - A POSSIBLE MECHANISM FOR ENHANCEMENT OF INJURY DURING CORONARY-OCCLUSION
Levin, RI; Cronstein, BN; Recht, PA; Buck, SW
1987 Apr;35(3):A297-A297, Clinical research
— id: 31364, year: 1987, vol: 35, page: A297, stat: Journal Article,

COCAINE DERIVATIVES ALTER PROSTACYCLIN/THROMBOXANE BALANCE - A MODEL FOR VASCULAR INJURY IN COCAINE ABUSE
Levin, RI; Kramer, JL; Silvers, AR; Recht, PA; Weissmann, G
1987 Apr;35(3):A297-A297, Clinical research
— id: 31365, year: 1987, vol: 35, page: A297, stat: Journal Article,

Non-steroidal anti-inflammatory drugs: how do they work?
Weissmann G; Korchak H; Ludewig R; Edelson H; Haines K; Levin RI; Herman R; Rider L; Kimmel S; Abramson S
1987 ;8(1):6-17, European journal of rheumatology & inflammation
— id: 59687, year: 1987, vol: 8, page: 6, stat: Journal Article,

Adenosine: an endogenous inhibitor of neutrophil-mediated injury to endothelial cells
Cronstein BN; Levin RI; Belanoff J; Weissmann G; Hirschhorn R
1986 Sep;78(3):760-770, Journal of clinical investigation
— id: 9841, year: 1986, vol: 78, page: 760, stat: Journal Article,

A NEW FUNCTION FOR ADENOSINE - PROTECTION OF VASCULAR ENDOTHELIAL-CELLS AGAINST NEUTROPHIL MEDIATED INJURY
CRONSTEIN, BN; LEVIN, RI; BELANOFF, J; WEISSMANN, G; HIRSCHHORN, R
1986 JUN 27 ;5(1):114-114, International journal of microcirculation, clinical & experimental
— id: 41387, year: 1986, vol: 5, page: 114, stat: Journal Article,

THE TRAVELING HEART
LEVIN, RI
1986 JUN 15 ;18(11):26-&, Emergency medicine
— id: 41292, year: 1986, vol: 18, page: 26, stat: Journal Article,

A REAL-TIME, INTERACTIVE, AMBULATORY, ELECTROCARDIOGRAPHIC MONITORING DEVICE FOR THE QUANTITATION OF MYOCARDIAL-ISCHEMIA
Levin, RI; Cohen, D; Frisbie, WR
1986 Apr;34(2):A320-A320, Clinical research
— id: 31030, year: 1986, vol: 34, page: A320, stat: Journal Article,

LONG-TERM AMBULATORY ECG MONITORING FOR OPTIMIZING ANTIISCHEMIC THERAPY
Levin, RI; Keller, B; Campbell, DQ
1986 Oct;74(4):190-190, Circulation
— id: 31011, year: 1986, vol: 74, page: 190, stat: Journal Article,

LONG-TERM, INTERACTIVE, AMBULATORY MONITORING - A NEW APPROACH TO TREATMENT OF MYOCARDIAL-ISCHEMIA
Levin, RI; Keller, B; Campbell, DQ
1986 Apr;34(2):A320-A320, Clinical research
— id: 31031, year: 1986, vol: 34, page: A320, stat: Journal Article,

ASPIRIN INHIBITS TISSUE PLASMINOGEN-ACTIVATOR ANTIGEN RELEASE AND FIBRINOLYTIC-ACTIVITY AFTER VENOUS OCCLUSION INVIVO
Levin, RI; Lovenvirth, WJ; Harpel, PC
1986 Oct;74(4):236-236, Circulation
— id: 31012, year: 1986, vol: 74, page: 236, stat: Journal Article,

ASPIRIN INHIBITS TISSUE PLASMINOGEN-ACTIVATOR ANTIGEN RELEASE AND FIBRINOLYTIC-ACTIVITY AFTER VENOUS OCCLUSION INVIVO
Levin, RI; Lovenvirth, WJ; Harpel, PC
1986 Apr;34(2):A709-A709, Clinical research
— id: 31045, year: 1986, vol: 34, page: A709, stat: Journal Article,

Modes of action of aspirin-like drugs
Abramson S; Korchak H; Ludewig R; Edelson H; Haines K; Levin RI; Herman R; Rider L; Kimmel S; Weissmann G
1985 Nov;82(21):7227-7231, Proceedings of the National Academy of Sciences of the United States of America
— id: 59701, year: 1985, vol: 82, page: 7227, stat: Journal Article,

HUMAN NEUTROPHIL ELASTASE MODULATES PLATELET-FUNCTION BY LIMITED PROTEOLYSIS OF MEMBRANE-GLYCOPROTEINS
BROWER, MS; LEVIN, RI; GARRY, K
1985 ;75(2):657-666, Journal of clinical investigation
— id: 41161, year: 1985, vol: 75, page: 657, stat: Journal Article,

Physician choices in the treatment of angina pectoris
Charap MH; Levin RI; Weinglass J
1985 Oct;79(4):461-466, American journal of medicine
— id: 18894, year: 1985, vol: 79, page: 461, stat: Journal Article,

A NEW FUNCTION FOR ADENOSINE - PROTECTION OF VASCULAR ENDOTHELIAL-CELLS AGAINST NEUTROPHIL MEDIATED INJURY
Cronstein, BN; Levin, RI; Belanoff, J; Weissmann, G; Hirschhorn, R
1985 ;33(2):A517-A517, Clinical research
— id: 30927, year: 1985, vol: 33, page: A517, stat: Journal Article,

A NITROGLYCERIN PARADOX - PHARMACOLOGIC DOSES ENHANCE WHILE SUPRAPHARMACOLOGIC DOSES SUPPRESS PLATELET-FUNCTION
Friedman, G; Belanoff, J; Nachamie, M; Silvers, A; Tager, D; Gindea, A; Levin, RI
1985 ;33(3):A752-A752, Clinical research
— id: 30725, year: 1985, vol: 33, page: A752, stat: Journal Article,

NITROGLYCERIN SYNERGISTICALLY ENHANCES PLATELET-FUNCTION
Friedman, G; Belanoff, J; Nachamie, M; Silvers, A; Tager, D; Gindea, A; Levin, RI
1985 ;33(2):A340-A340, Clinical research
— id: 30747, year: 1985, vol: 33, page: A340, stat: Journal Article,

THE EFFECT OF ASPIRIN ON THE PHYSIOLOGIC RESPONSE TO NITROGLYCERIN
Levin, RI; Feit, F; Jaffe, E
1985 ;33(3):A744-A744, Clinical research
— id: 30724, year: 1985, vol: 33, page: A744, stat: Journal Article,

THE EFFECT OF ASPIRIN ON THE PHYSIOLOGIC RESPONSE TO NITROGLYCERIN
Levin, RI; Feit, F; Jaffe, EA
1985 ;72(4):460-460, Circulation
— id: 30722, year: 1985, vol: 72, page: 460, stat: Journal Article,

THE PHYSIOLOGIC RESPONSE TO NITROGLYCERIN IS NOT MEDIATED BY PROSTACYCLIN
Levin, RI; Feit, F; Jaffe, EA
1985 ;33(2):A520-A520, Clinical research
— id: 30750, year: 1985, vol: 33, page: A520, stat: Journal Article,

LEFT ATRIAL PULMONARY-ARTERY WEDGE PRESSURE RELATION - EFFECT OF ELEVATED PULMONARY VASCULAR-RESISTANCE
Levin, RI; Glassman, E
1985 ;55(6):856-857, American journal of cardiology
— id: 30785, year: 1985, vol: 55, page: 856, stat: Journal Article,

ROLE OF THROMBOXANE-A2 (TXA2) AND PROSTAGLANDIN-I2 (PGI2) ON ALTERED GLOMERULAR FUNCTION IN GENTAMICIN TREATED RATS
Negri, AL; Levin, RI; Dworkin, LD
1985 ;27(1):235-235, Kidney international
— id: 30988, year: 1985, vol: 27, page: 235, stat: Journal Article,

GENERATION OF PLASMIN-INHIBITOR-PLASMIN COMPLEXES IN PLASMA BY TISSUE PLASMINOGEN-ACTIVATOR AND UROKINASE
HARPEL, PC; WEIL, D; LEVIN, RI; RIFKIN, DB
1984 ;14(1):67-67, Haemostasis
— id: 40843, year: 1984, vol: 14, page: 67, stat: Journal Article,

Aspirin inhibits vascular plasminogen activator activity in vivo. Studies utilizing a new assay to quantify plasminogen activator activity
Levin RI; Harpel PC; Weil D; Chang TS; Rifkin DB
1984 Aug;74(2):571-580, Journal of clinical investigation
— id: 57531, year: 1984, vol: 74, page: 571, stat: Journal Article,

ASPIRIN INHIBITS VASCULAR PLASMINOGEN-ACTIVATOR ACTIVITY INVIVO
LEVIN, RI; HARPEL, PC
1984 ;32(2):A497-A497, Clinical research
— id: 40832, year: 1984, vol: 32, page: A497, stat: Journal Article,

THE SPECTRUM OF PLATELET INHIBITION BY THE THROMBOXANE SYNTHETASE INHIBITOR OKY046
LEVIN, RI; NEGRI, AL; DWORKIN, LD
1984 ;32(2):A314-A314, Clinical research
— id: 40826, year: 1984, vol: 32, page: A314, stat: Journal Article,

ANGINA-PECTORIS - PHYSICIAN CHARACTERISTICS PREDICT MANAGEMENT - A CASE VIGNETTE SURVEY METHOD
CHARAP, MH; LEVIN, R; WEINGLASS, J
1983 ;31(2):A637-A637, Clinical research
— id: 40556, year: 1983, vol: 31, page: A637, stat: Journal Article,

HUMAN-LEUKOCYTE ELASTASE INHIBITS THROMBIN-INDUCED PLATELET-AGGREGATION
LEVIN, RI; BROWER, MS
1983 ;31(2):A483-A483, Clinical research
— id: 40550, year: 1983, vol: 31, page: A483, stat: Journal Article,

The urban emergency department: the issue of professional responsibility
Abrams, N; Buckner, M D; Levin, R I
1982 Feb;11(2):86-90, Annals of emergency medicine
— id: 527762, year: 1982, vol: 11, page: 86, stat: Journal Article,

HEPATITIS IN HUMAN-SUBJECTS ASSOCIATED WITH TOCAINIDE ADMINISTRATION
Levin, RI; Fox, AC
1982 ;30(2):A200-A200, Clinical research
— id: 30551, year: 1982, vol: 30, page: A200, stat: Journal Article,

THE EFFECT OF SODIUM OXALATE ON HUMAN-ENDOTHELIAL CELLS
Levin, RI; Jaffe, EA; Weksler, BB; Kantoff, PW; Minick, CR
1982 ;2(5):A413-A413, Arteriosclerosis
— id: 30518, year: 1982, vol: 2, page: A413, stat: Journal Article,

THE EFFECT OF SODIUM OXALATE ON HUMAN-ENDOTHELIAL CELLS
Levin, RI; Jaffe, EA; Weksler, BB; Kantoff, PW; Minick, CR
1982 ;66(4):39-39, Circulation
— id: 30521, year: 1982, vol: 66, page: 39, stat: Journal Article,

THE PRODUCTS OF UREMIA ARE TOXIC TO HUMAN-ENDOTHELIAL CELLS
Levin, RI; Jaffe, EA; Weksler, BB; Minick, CR
1982 ;30(2):A483-A483, Clinical research
— id: 30559, year: 1982, vol: 30, page: A483, stat: Journal Article,

THE INTERACTION OF ERGONOVINE MALEATE WITH HUMAN-ENDOTHELIAL CELLS AND PLATELETS
Levin, RI; Weksler, BB; Jaffe, EA
1982 ;30(2):A201-A201, Clinical research
— id: 30552, year: 1982, vol: 30, page: A201, stat: Journal Article,

THE INTERACTION OF SODIUM-NITROPRUSSIDE WITH HUMAN-ENDOTHELIAL CELLS AND PLATELETS - NITROPRUSSIDE AND PROSTACYCLIN SYNERGISTICALLY INHIBIT PLATELET-FUNCTION
Levin, RI; Weksler, BB; Jaffe, EA
1982 ;66(6):1299-1307, Circulation
— id: 30298, year: 1982, vol: 66, page: 1299, stat: Journal Article,

NITROPRUSSIDE AND PROSTACYCLIN ARE SYNERGIC IN SUPPRESSING PLATELET-AGGREGATION
Levin, RI; Jaffe, EA; Weksler, BB; Tackgoldman, K
1980 ;62(4):309-309, Circulation
— id: 28096, year: 1980, vol: 62, page: 309, stat: Journal Article,

NITROGLYCERIN INDUCES PRODUCTION OF PROSTACYCLIN BY HUMAN- ENDOTHELIAL CELLS
Levin, RI; Weksler, BB; Jaffe, EA
1980 ;28(2):A471-A471, Clinical research
— id: 28115, year: 1980, vol: 28, page: A471, stat: Journal Article,

Changes in renal function and intrarenal blood flow
Vargish, T; Levin, R; Cotton, J; Cukingnan, R A; Boyd, J C; Stahl, W M
1973 Oct;178(4):496-502, Annals of surgery
— id: 130635, year: 1973, vol: 178, page: 496, stat: Journal Article,