Nathaniel R. Landau

Biosketch / Results /

Nathaniel R. Landau, D.Phil., Ph.D.

Professor;
Department of Microbiology (Microbiology )

Contact Info

Address
522 First Avenue
Dept of Microbiology Floor 10 Room 1003
Smilow Research Building
New York, NY 10016

212-263-9197
Nathaniel.Landau@med.nyu.edu

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Education

— Dr. Landau was a Postdoctoral Associate at MIT in 1986. He was a Fellow of the Cancer Research Institute at the University of California, San Francisco from 1987-1991, PostDoctoral Training
1986 — MIT, Medical Education
1986 — MIT, Graduate Education

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All data from NYU Health Sciences Library Faculty Bibliography — -

Contact:
http://hsl.med.nyu.edu/faculty-bibliography-search

Interactions with DCAF1 and DDB1 in the CRL4 E3 ubiquitin ligase are required for Vpr-mediated G2 arrest
Hakata, Yoshiyuki; Miyazawa, Masaaki; Landau, Nathaniel R
2014 ;11(1):108-108, Virology journal
— id: 1042312, year: 2014, vol: 11, page: 108, stat: Journal Article,

Inhibition of Cul4A Neddylation Causes a Reversible Block To SAMHD1-Mediated Restriction of HIV-1
Hofmann, H; Norton, T D; Logue, E C; Schultz, M L; Polsky, S B; Sunseri, N; Landau, N R
2014 Apr 2014;(568(pages22):25-25, Topics in antiviral medicine
— id: 1291982, year: 2014, vol: (568, page: 25, stat: Journal Article,

SAMHD1 Has Differential Impact on the Efficacies of HIV Nucleoside Reverse Transcriptase Inhibitors
Huber, Andrew D; Michailidis, Eleftherios; Schultz, Megan L; Ong, Yee T; Bloch, Nicolin; Puray-Chavez, Maritza N; Leslie, Maxwell D; Ji, Juan; Lucas, Anthony D; Kirby, Karen A; Landau, Nathaniel R; Sarafianos, Stefan G
2014 Aug;58(8):4915-4919, Antimicrobial agents & chemotherapy
— id: 1153732, year: 2014, vol: 58, page: 4915, stat: Journal Article,

The Innate Immune Response to HIV-1: To Sense or Not to Sense
Landau, Nathaniel R
2014 May;33(5):271-274, DNA & cell biology
— id: 970082, year: 2014, vol: 33, page: 271, stat: Journal Article,

A DNA Sequence Recognition Loop on APOBEC3A Controls Substrate Specificity
Logue, Eric C; Bloch, Nicolin; Dhuey, Erica; Zhang, Ruonan; Cao, Ping; Herate, Cecile; Chauveau, Lise; Hubbard, Stevan R; Landau, Nathaniel R
2014 ;9(5):e97062-e97062 e97062, PLoS one
— id: 996992, year: 2014, vol: 9, page: e97062, stat: Journal Article,

Host restriction of murine gammaherpesvirus 68 replication by human APOBEC3 cytidine deaminases but not murine APOBEC3
Minkah, Nana; Chavez, Kevin; Shah, Parth; Maccarthy, Thomas; Chen, Hui; Landau, Nathaniel; Krug, Laurie T
2014 Apr;454-455:215-226, Virology
— id: 882002, year: 2014, vol: 454-455, page: 215, stat: Journal Article,

SAMHD1 Restricts HIV-1 Replication and Regulates Interferon Production in Mouse Myeloid Cells
Zhang, Ruonan; Bloch, Nicolin; Nguyen, Laura A; Kim, Baek; Landau, Nathaniel R
2014 ;9(2):e89558-e89558 e89558, PLoS one
— id: 829622, year: 2014, vol: 9, page: e89558, stat: Journal Article,

CCR5 is a receptor for Staphylococcus aureus leukotoxin ED
Alonzo, Francis 3rd; Kozhaya, Lina; Rawlings, Stephen A; Reyes-Robles, Tamara; DuMont, Ashley L; Myszka, David G; Landau, Nathaniel R; Unutmaz, Derya; Torres, Victor J
2013 Jan;493(7430):51-55, Nature
— id: 211102, year: 2013, vol: 493, page: 51, stat: Journal Article,

HIV Type 1 Infection of Plasmacytoid and Myeloid Dendritic Cells Is Restricted by High Levels of SAMHD1 and Cannot be Counteracted by Vpx
Bloch, Nicolin; O'Brien, Meagan; Norton, Thomas D; Polsky, Sylvie B; Bhardwaj, Nina; Landau, Nathaniel R
2013 Sep;:195-203, AIDS research & human retroviruses
— id: 674952, year: 2013, vol: , page: 195, stat: Journal Article,

Efficient transduction of myeloid cells by an HIV-1-derived lentiviral vector that packages the Vpx accessory protein
Bobadilla, S; Sunseri, N; Landau, N R
2013 May;20(5):514-520, Gene therapy
— id: 335432, year: 2013, vol: 20, page: 514, stat: Journal Article,

Restriction of diverse retroviruses by SAMHD1
Gramberg, Thomas; Kahle, Tanja; Bloch, Nicolin; Wittmann, Sabine; Mullers, Erik; Daddacha, Waaqo; Hofmann, Henning; Kim, Baek; Lindemann, Dirk; Landau, Nathaniel R
2013 ;10:26-26, Retrovirology
— id: 248242, year: 2013, vol: 10, page: 26, stat: Journal Article,

Inhibition of CUL4A Neddylation Causes a Reversible Block to SAMHD1-Mediated Restriction of HIV-1
Hofmann, Henning; Norton, Thomas D; Schultz, Megan L; Polsky, Sylvie B; Sunseri, Nicole; Landau, Nathaniel R
2013 Nov;87(21):11741-11750, Journal of virology
— id: 573852, year: 2013, vol: 87, page: 11741, stat: Journal Article,

Vpx improves nuclear import and uncovers a restriction to lentiviral integration in quiescent human hematopoietic stem and progenitor cells
Petrillo, C.; Piras, F.; Bartolaccini, S.; Landau, N. R.; Naldini, L.; Kajaste-Rudnitski, A.
2013 DEC 1;24(12):A73-A73, Human gene therapy
— id: 781392, year: 2013, vol: 24, page: A73, stat: Journal Article,

SAMHD1 restricts HIV-1 infection in resting CD4(+) T cells
Baldauf, Hanna-Mari; Pan, Xiaoyu; Erikson, Elina; Schmidt, Sarah; Daddacha, Waaqo; Burggraf, Manja; Schenkova, Kristina; Ambiel, Ina; Wabnitz, Guido; Gramberg, Thomas; Panitz, Sylvia; Flory, Egbert; Landau, Nathaniel R; Sertel, Serkan; Rutsch, Frank; Lasitschka, Felix; Kim, Baek; Konig, Renate; Fackler, Oliver T; Keppler, Oliver T
2012 Nov;18(11):1682-1687, Nature medicine
— id: 185452, year: 2012, vol: 18, page: 1682, stat: Journal Article,

The Vpx Lentiviral Accessory Protein Targets SAMHD1 for Degradation in the Nucleus
Hofmann, Henning; Logue, Eric C; Bloch, Nicolin; Daddacha, Waaqo; Polsky, Sylvie B; Schultz, Megan L; Kim, Baek; Landau, Nathaniel R
2012 Dec;86(23):12552-12560, Journal of virology
— id: 184822, year: 2012, vol: 86, page: 12552, stat: Journal Article,

SAMHD1 restricts the replication of human immunodeficiency virus type 1 by depleting the intracellular pool of deoxynucleoside triphosphates
Lahouassa, Hichem; Daddacha, Waaqo; Hofmann, Henning; Ayinde, Diana; Logue, Eric C; Dragin, Loic; Bloch, Nicolin; Maudet, Claire; Bertrand, Matthieu; Gramberg, Thomas; Pancino, Gianfranco; Priet, Stephane; Canard, Bruno; Laguette, Nadine; Benkirane, Monsef; Transy, Catherine; Landau, Nathaniel R; Kim, Baek; Margottin-Goguet, Florence
2012 ;13(3):223-228, Nature immunology
— id: 158627, year: 2012, vol: 13, page: 223, stat: Journal Article,

The cargo-binding domain of transportin 3 is required for lentivirus nuclear import
Logue, Eric C; Taylor, Kayleigh T; Goff, Peter H; Landau, Nathaniel R
2011 Dec;85(24):12950-12961, Journal of virology
— id: 141700, year: 2011, vol: 85, page: 12950, stat: Journal Article,

Human immunodeficiency virus type 1 modified to package simian immunodeficiency virus vpx efficiently infects macrophages and dendritic cells
Sunseri, Nicole; O'Brien, Meagan; Bhardwaj, Nina; Landau, Nathaniel R
2011 Jul;85(13):6263-6274, Journal of virology
— id: 134443, year: 2011, vol: 85, page: 6263, stat: Journal Article,

Evidence for an Activation Domain at the Amino-terminus of SIV Vpx
Gramberg, Thomas; Sunseri, Nicole; Landau, Nathaniel R
2010 Feb;84(3):1387-1396, Journal of virology
— id: 105999, year: 2010, vol: 84, page: 1387, stat: Journal Article,

Restriction of HIV-1 by APOBEC3G is cytidine deaminase-dependent
Browne, Edward P; Allers, Carolina; Landau, Nathaniel R
2009 May 10;387(2):313-321, Virology
— id: 99588, year: 2009, vol: 387, page: 313, stat: Journal Article,

Accessories to the crime: recent advances in HIV accessory protein biology
Gramberg, Thomas; Sunseri, Nicole; Landau, Nathaniel R
2009 Feb;6(1):36-42, Current HIV/AIDS reports
— id: 97756, year: 2009, vol: 6, page: 36, stat: Journal Article,

Guidelines for naming nonprimate APOBEC3 genes and proteins
LaRue, Rebecca S; Andresdottir, Valgerdur; Blanchard, Yannick; Conticello, Silvestro G; Derse, David; Emerman, Michael; Greene, Warner C; Jonsson, Stefan R; Landau, Nathaniel R; Lochelt, Martin; Malik, Harmit S; Malim, Michael H; Munk, Carsten; O'Brien, Stephen J; Pathak, Vinay K; Strebel, Klaus; Wain-Hobson, Simon; Yu, Xiao-Fang; Yuhki, Naoya; Harris, Reuben S
2009 Jan;83(2):494-497, Journal of virology
— id: 106001, year: 2009, vol: 83, page: 494, stat: Journal Article,

Inhibition of Adeno-Associated Virus by the Host Factors APOBEC3A and APOBEC3B
Narvaiza, I; Linfesty, DC; Greener, BN; Hakata, Y; Lilley, CE; Landau, NR; Weitzman, MD
2009 MAY ;17(10):S146-S146, Molecular therapy
— id: 111898, year: 2009, vol: 17, page: S146, stat: Journal Article,

Deaminase-independent inhibition of parvoviruses by the APOBEC3A cytidine deaminase
Narvaiza, Inigo; Linfesty, Daniel C; Greener, Benjamin N; Hakata, Yoshiyuki; Pintel, David J; Logue, Eric; Landau, Nathaniel R; Weitzman, Matthew D
2009 May;5(5):e1000439-e1000439, PLoS pathogens
— id: 106000, year: 2009, vol: 5, page: e1000439, stat: Journal Article,

Analysis of Vif-induced APOBEC3G degradation using an alpha-complementation assay
Fang, Lei; Landau, Nathaniel R
2007 Mar 1;359(1):162-169, Virology
— id: 72039, year: 2007, vol: 359, page: 162, stat: Journal Article,

HIV-1 Vpr function is mediated by interaction with the damage-specific DNA-binding protein DDB1
Schrofelbauer, Barbel; Hakata, Yoshiyuki; Landau, Nathaniel R
2007 Mar 6;104(10):4130-4135, Proceedings of the National Academy of Sciences of the United States of America
— id: 72038, year: 2007, vol: 104, page: 4130, stat: Journal Article,

APOBEC3A is a potent inhibitor of adeno-associated virus and retrotransposons
Chen, Hui; Lilley, Caroline E; Yu, Qin; Lee, Darwin V; Chou, Jody; Narvaiza, Inigo; Landau, Nathaniel R; Weitzman, Matthew D
2006 Mar 7;16(5):480-485, Current biology. CB
— id: 68236, year: 2006, vol: 16, page: 480, stat: Journal Article,

Reversed functional organization of mouse and human APOBEC3 cytidine deaminase domains
Hakata, Yoshiyuki; Landau, Nathaniel R
2006 Dec 1;281(48):36624-36631, Journal of biological chemistry
— id: 72040, year: 2006, vol: 281, page: 36624, stat: Journal Article,

Mutational alteration of human immunodeficiency virus type 1 Vif allows for functional interaction with nonhuman primate APOBEC3G
Schrofelbauer, Barbel; Senger, Tilo; Manning, Gerard; Landau, Nathaniel R
2006 Jun;80(12):5984-5991, Journal of virology
— id: 68235, year: 2006, vol: 80, page: 5984, stat: Journal Article,

Complementary function of the two catalytic domains of APOBEC3G
Navarro, Francisco; Bollman, Brooke; Chen, Hui; Konig, Renate; Yu, Qin; Chiles, Kristopher; Landau, Nathaniel R
2005 Mar 15;333(2):374-386, Virology
— id: 68238, year: 2005, vol: 333, page: 374, stat: Journal Article,

Human immunodeficiency virus type 1 Vpr induces the degradation of the UNG and SMUG uracil-DNA glycosylases
Schrofelbauer, Barbel; Yu, Qin; Zeitlin, Samantha G; Landau, Nathaniel R
2005 Sep;79(17):10978-10987, Journal of virology
— id: 68237, year: 2005, vol: 79, page: 10978, stat: Journal Article,

Alpha-complementation assay for HIV envelope glycoprotein-mediated fusion
Holland, Anne U; Munk, Carsten; Lucero, Ginger R; Nguyen, Lucia D; Landau, Nathaniel R
2004 Feb 20;319(2):343-352, Virology
— id: 68243, year: 2004, vol: 319, page: 343, stat: Journal Article,

Recent insights into HIV-1 Vif
Navarro, Francisco; Landau, Nathaniel R
2004 Aug;16(4):477-482, Current opinion in immunology
— id: 68240, year: 2004, vol: 16, page: 477, stat: Journal Article,

A single amino acid of APOBEC3G controls its species-specific interaction with virion infectivity factor (Vif)
Schrofelbauer, Barbel; Chen, Darlene; Landau, Nathaniel R
2004 Mar 16;101(11):3927-3932, Proceedings of the National Academy of Sciences of the United States of America
— id: 68244, year: 2004, vol: 101, page: 3927, stat: Journal Article,

New insights into the role of Vif in HIV-1 replication
Schrofelbauer, Barbel; Yu, Qin; Landau, Nathaniel R
2004 Jan-Mar;6(1):34-39, AIDS reviews
— id: 68241, year: 2004, vol: 6, page: 34, stat: Journal Article,

APOBEC3B and APOBEC3C are potent inhibitors of simian immunodeficiency virus replication
Yu, Qin; Chen, Darlene; Konig, Renate; Mariani, Roberto; Unutmaz, Derya; Landau, Nathaniel R
2004 Dec 17;279(51):53379-53386, Journal of biological chemistry
— id: 68239, year: 2004, vol: 279, page: 53379, stat: Journal Article,

Single-strand specificity of APOBEC3G accounts for minus-strand deamination of the HIV genome
Yu, Qin; Konig, Renate; Pillai, Satish; Chiles, Kristopher; Kearney, Mary; Palmer, Sarah; Richman, Douglas; Coffin, John M; Landau, Nathaniel R
2004 May;11(5):435-442, Nature structural & molecular biology
— id: 68242, year: 2004, vol: 11, page: 435, stat: Journal Article,

HIV-1 Vpr activates cell cycle inhibitor p21/Waf1/Cip1: a potential mechanism of G2/M cell cycle arrest
Chowdhury, Iqbal H; Wang, Xiao-Fan; Landau, Nathaniel R; Robb, Merlin L; Polonis, Victoria R; Birx, Deborah L; Kim, Jerome H
2003 Jan 20;305(2):371-377, Virology
— id: 68248, year: 2003, vol: 305, page: 371, stat: Journal Article,

Inhibition of HIV-1 infection by a CCR5-binding cyclophilin from Toxoplasma gondii
Golding, Hana; Aliberti, Julio; King, Lisa R; Manischewitz, Jody; Andersen, John; Valenzuela, Jesus; Landau, Nathaniel R; Sher, Alan
2003 Nov 1;102(9):3280-3286, Blood
— id: 68247, year: 2003, vol: 102, page: 3280, stat: Journal Article,

Abrogation of postentry restriction of HIV-1-based lentiviral vector transduction in simian cells
Kootstra, Neeltje A; Munk, Carsten; Tonnu, Nina; Landau, Nathaniel R; Verma, Inder M
2003 Feb 4;100(3):1298-1303, Proceedings of the National Academy of Sciences of the United States of America
— id: 68249, year: 2003, vol: 100, page: 1298, stat: Journal Article,

Species-specific exclusion of APOBEC3G from HIV-1 virions by Vif
Mariani, Roberto; Chen, Darlene; Schrofelbauer, Barbel; Navarro, Francisco; Konig, Renate; Bollman, Brooke; Munk, Carsten; Nymark-McMahon, Henrietta; Landau, Nathaniel R
2003 Jul 11;114(1):21-31, Cell
— id: 68246, year: 2003, vol: 114, page: 21, stat: Journal Article,

The theta-defensin, retrocyclin, inhibits HIV-1 entry
Munk, Carsten; Wei, Ge; Yang, Otto O; Waring, Alan J; Wang, Wei; Hong, Teresa; Lehrer, Robert I; Landau, Nathaniel R; Cole, Alexander M
2003 Oct;19(10):875-881, AIDS research & human retroviruses
— id: 68245, year: 2003, vol: 19, page: 875, stat: Journal Article,

Association of chemokine-mediated block to HIV entry with coreceptor internalization
Brandt, Stephanie M; Mariani, Roberto; Holland, Anne U; Hope, Thomas J; Landau, Nathaniel R
2002 May 10;277(19):17291-17299, Journal of biological chemistry
— id: 68253, year: 2002, vol: 277, page: 17291, stat: Journal Article,

A cellular cofactor in HIV-1 assembly: INI1 is also an "outtie"
Landau, Nathaniel R
2002 Jun;23(6):252-253, Trends in pharmacological science
— id: 68252, year: 2002, vol: 23, page: 252, stat: Journal Article,

A dominant block to HIV-1 replication at reverse transcription in simian cells
Munk, Carsten; Brandt, Stephanie M; Lucero, Ginger; Landau, Nathaniel R
2002 Oct 15;99(21):13843-13848, Proceedings of the National Academy of Sciences of the United States of America
— id: 68250, year: 2002, vol: 99, page: 13843, stat: Journal Article,

Chimeric human immunodeficiency virus type 1 containing murine leukemia virus matrix assembles in murine cells
Reed, Margaret; Mariani, Roberto; Sheppard, Liana; Pekrun, Katja; Landau, Nathaniel R; Soong, Nay-Wei
2002 Jan;76(1):436-443, Journal of virology
— id: 68254, year: 2002, vol: 76, page: 436, stat: Journal Article,

Vpr- and Nef-dependent induction of RANTES/CCL5 in microglial cells
Si, Qiusheng; Kim, Mee-Ohk; Zhao, Meng-Liang; Landau, Nathaniel R; Goldstein, Harris; Lee, Sunhee
2002 Sep 30;301(2):342-353, Virology
— id: 68251, year: 2002, vol: 301, page: 342, stat: Journal Article,

Mouse-human heterokaryons support efficient human immunodeficiency virus type 1 assembly
Mariani, R; Rasala, B A; Rutter, G; Wiegers, K; Brandt, S M; Krausslich, H G; Landau, N R
2001 Apr;75(7):3141-3151, Journal of virology
— id: 68255, year: 2001, vol: 75, page: 3141, stat: Journal Article,

Soluble CD40 ligand induces beta-chemokine production by macrophages and resistance to HIV-1 entry
di Marzio, P; Mariani, R; Lui, R; Thomas, E K; Landau, N R
2000 Oct;12(10):1489-1495, Cytokine
— id: 68256, year: 2000, vol: 12, page: 1489, stat: Journal Article,

A block to human immunodeficiency virus type 1 assembly in murine cells
Mariani, R; Rutter, G; Harris, M E; Hope, T J; Krausslich, H G; Landau, N R
2000 Apr;74(8):3859-3870, Journal of virology
— id: 68258, year: 2000, vol: 74, page: 3859, stat: Journal Article,

Aminooxypentane addition to the chemokine macrophage inflammatory protein-1alpha P increases receptor affinities and HIV inhibition
Townson, J R; Graham, G J; Landau, N R; Rasala, B; Nibbs, R J
2000 Dec 15;275(50):39254-39261, Journal of biological chemistry
— id: 68257, year: 2000, vol: 275, page: 39254, stat: Journal Article,

HIV recent advances in AIDS research: genetics, molecular biology and immunology
Landau, N R
1999 Aug;11(4):449-450, Current opinion in immunology
— id: 68259, year: 1999, vol: 11, page: 449, stat: Journal Article,

CCR2-64I polymorphism is not associated with altered CCR5 expression or coreceptor function
Mariani R; Wong S; Mulder LC; Wilkinson DA; Reinhart AL; LaRosa G; Nibbs R; O'Brien TR; Michael NL; Connor RI; Macdonald M; Busch M; Koup RA; Landau NR
1999 Mar;73(3):2450-2459, Journal of virology
— id: 65550, year: 1999, vol: 73, page: 2450, stat: Journal Article,

Altered expression of CD4, CD54, CD62L, and CCR5 in primary lymphocytes productively infected with the human immunodeficiency virus
Marodon, G; Landau, N R; Posnett, D N
1999 Jan 20;15(2):161-171, AIDS research & human retroviruses
— id: 68261, year: 1999, vol: 15, page: 161, stat: Journal Article,

LD78beta, a non-allelic variant of human MIP-1alpha (LD78alpha), has enhanced receptor interactions and potent HIV suppressive activity
Nibbs, R J; Yang, J; Landau, N R; Mao, J H; Graham, G J
1999 Jun 18;274(25):17478-17483, Journal of biological chemistry
— id: 68260, year: 1999, vol: 274, page: 17478, stat: Journal Article,

HIV-1 infectability of CD4+ lymphocytes with relation to beta-chemokines and the CCR5 coreceptor
Paxton WA; Kang S; Liu R; Landau NR; Gingeras TR; Wu L; Mackay CR; Koup RA
1999 Mar;66(1-3):71-75, Immunology letters
— id: 65546, year: 1999, vol: 66, page: 71, stat: Journal Article,

New developments in the biology and treatment of HIV
Bushman, F; Landau, N R; Emini, E A
1998 Sep 15;95(19):11041-11042, Proceedings of the National Academy of Sciences of the United States of America
— id: 68263, year: 1998, vol: 95, page: 11041, stat: Journal Article,

Chemokine receptor regulation and HIV type 1 tropism in monocyte-macrophages
Di Marzio, P; Tse, J; Landau, N R
1998 Jan 20;14(2):129-138, AIDS research & human retroviruses
— id: 68264, year: 1998, vol: 14, page: 129, stat: Journal Article,

Functional analysis of the proximal CCR5 promoter
Liu, R; Zhao, X; Gurney, T A; Landau, N R
1998 Nov 20;14(17):1509-1519, AIDS research & human retroviruses
— id: 68262, year: 1998, vol: 14, page: 1509, stat: Journal Article,

Reduced HIV-1 infectability of CD4+ lymphocytes from exposed-uninfected individuals: association with low expression of CCR5 and high production of beta-chemokines
Paxton WA; Liu R; Kang S; Wu L; Gingeras TR; Landau NR; Mackay CR; Koup RA
1998 Apr 25;244(1):66-73, Virology
— id: 65556, year: 1998, vol: 244, page: 66, stat: Journal Article,

Genetically divergent strains of simian immunodeficiency virus use CCR5 as a coreceptor for entry
Chen Z; Zhou P; Ho DD; Landau NR; Marx PA
1997 Apr;71(4):2705-2714, Journal of virology
— id: 57530, year: 1997, vol: 71, page: 2705, stat: Journal Article,

Macrophage tropism of human immunodeficiency virus type 1 and utilization of the CC-CKR5 coreceptor
Cheng-Mayer, C; Liu, R; Landau, N R; Stamatatos, L
1997 Feb;71(2):1657-1661, Journal of virology
— id: 68268, year: 1997, vol: 71, page: 1657, stat: Journal Article,

Change in coreceptor use coreceptor use correlates with disease progression in HIV-1--infected individuals
Connor, R I; Sheridan, K E; Ceradini, D; Choe, S; Landau, N R
1997 Feb 17;185(4):621-628, Journal of experimental medicine
— id: 68267, year: 1997, vol: 185, page: 621, stat: Journal Article,

HIV co-receptor identification: good or bad news for drug discovery?
Landau, N R
1997 Oct;9(5):628-630, Current opinion in immunology
— id: 68266, year: 1997, vol: 9, page: 628, stat: Journal Article,

CCR-5: A hot target for drug discovery
Landau, NR; Liu, R; DiMarzio, P; Choe, S; Ceradini, D; Yang, J; Paxton, WA; Koup, RA
1997 JUL 31 ;11(9):A855-A855, FASEB journal
— id: 146290, year: 1997, vol: 11, page: A855, stat: Journal Article,

Cloning and characterization of a novel promiscuous human beta-chemokine receptor D6
Nibbs, R J; Wylie, S M; Yang, J; Landau, N R; Graham, G J
1997 Dec 19;272(51):32078-32083, Journal of biological chemistry
— id: 68265, year: 1997, vol: 272, page: 32078, stat: Journal Article,

Identification of a major co-receptor for primary isolates of HIV-1
Deng H; Liu R; Ellmeier W; Choe S; Unutmaz D; Burkhart M; Di Marzio P; Marmon S; Sutton RE; Hill CM; Davis CB; Peiper SC; Schall TJ; Littman DR; Landau NR
1996 Jun 20;381(6584):661-666, Nature
— id: 57390, year: 1996, vol: 381, page: 661, stat: Journal Article,

CD4-independent infection by HIV-2 is mediated by fusin/CXCR4
Endres, M J; Clapham, P R; Marsh, M; Ahuja, M; Turner, J D; McKnight, A; Thomas, J F; Stoebenau-Haggarty, B; Choe, S; Vance, P J; Wells, T N; Power, C A; Sutterwala, S S; Doms, R W; Landau, N R; Hoxie, J A
1996 Nov 15;87(4):745-756, Cell
— id: 68269, year: 1996, vol: 87, page: 745, stat: Journal Article,

The role of a mutant CCR5 allele in HIV-1 transmission and disease progression
Huang Y; Paxton WA; Wolinsky SM; Neumann AU; Zhang L; He T; Kang S; Ceradini D; Jin Z; Yazdanbakhsh K; Kunstman K; Erickson D; Dragon E; Landau NR; Phair J; Ho DD; Koup RA
1996 Nov;2(11):1240-1243, Nature medicine
— id: 65569, year: 1996, vol: 2, page: 1240, stat: Journal Article,

Homozygous defect in HIV-1 coreceptor accounts for resistance of some multiply-exposed individuals to HIV-1 infection
Liu R; Paxton WA; Choe S; Ceradini D; Martin SR; Horuk R; MacDonald ME; Stuhlmann H; Koup RA; Landau NR
1996 Aug 9;86(3):367-377, Cell
— id: 65571, year: 1996, vol: 86, page: 367, stat: Journal Article,

HIV-1 VPR AND SIV VPR AND VPX ARE DIRECTLY DEPENDENT ON GAG P6 FOR INCORPORATION INTO VIRIONS
CHOE, S; LU, T; LANDAU, N
1995 APR 2 ;54(3):187-187, Journal of cellular biochemistry
— id: 87310, year: 1995, vol: 54, page: 187, stat: Journal Article,

Vpr is required for efficient replication of human immunodeficiency virus type-1 in mononuclear phagocytes
Connor RI; Chen BK; Choe S; Landau NR
1995 Feb 1;206(2):935-944, Virology
— id: 6595, year: 1995, vol: 206, page: 935, stat: Journal Article,

Structural and functional studies on HIV-1 Vpr suggest the importance of a predicted alpha-helical amino-terminal domain
Di Marzio P; Choe S; Connor RI; Knoblauch R; Ebright M; Isakoff S; Landau NR
1995 Jan 29-Feb 2;2:60-60, National Conference on Human Retroviruses & Related Infections
— id: 5984, year: 1995, vol: 2, page: 60, stat: Journal Article,

Mutational analysis of cell cycle arrest, nuclear localization and virion packaging of human immunodeficiency virus type 1 Vpr
Di Marzio, P; Choe, S; Ebright, M; Knoblauch, R; Landau, N R
1995 Dec;69(12):7909-7916, Journal of virology
— id: 68270, year: 1995, vol: 69, page: 7909, stat: Journal Article,

STRUCTURAL AND FUNCTIONAL-STUDIES ON HIV-1 VPR SUGGEST THE IMPORTANCE ON A PREDICTED ALPHA-HELICAL AMINO-TERMINAL DOMAIN AND SUGGEST THAT VPR BLOCKS CELL-DIVISION IN G2 OF THE CELL-CYCLE
DIMARZIO, P; CHOE, S; EBRIGHT, M; KNOBLAUCH, R; ISAKOFF, S; LANDAU, NR
1995 APR 2 ;54(3):188-188, Journal of cellular biochemistry
— id: 87311, year: 1995, vol: 54, page: 188, stat: Journal Article,

Human immunodeficiency virus type 1 viral protein R (Vpr) arrests cells in the G2 phase of the cell cycle by inhibiting p34cdc2 activity
He J; Choe S; Walker R; Di Marzio P; Morgan DO; Landau NR
1995 Nov;69(11):6705-6711, Journal of virology
— id: 56820, year: 1995, vol: 69, page: 6705, stat: Journal Article,

Use of a novel human immunodeficiency virus type 1 reporter virus expressing human placental alkaline phosphatase to detect an alternative viral receptor
He J; Landau NR
1995 Jul;69(7):4587-4592, Journal of virology
— id: 12753, year: 1995, vol: 69, page: 4587, stat: Journal Article,

CONSTRUCTION AND USE OF AN HIV-1 REPORTER VIRUS EXPRESSING HUMAN-PLACENTAL ALKALINE-PHOSPHATASE
HE, JL; ISAKOFF, S; LANDAU, NR
1995 APR 2 ;54(3):191-191, Journal of cellular biochemistry
— id: 87312, year: 1995, vol: 54, page: 191, stat: Journal Article,

Nef induces CD4 endocytosis: requirement for a critical dileucine motif in the membrane-proximal CD4 cytoplasmic domain
Aiken, C; Konner, J; Landau, N R; Lenburg, M E; Trono, D
1994 Mar 11;76(5):853-864, Cell
— id: 68271, year: 1994, vol: 76, page: 853, stat: Journal Article,

CYTOPLASMIC DOMAIN OF CD4 IS SUFFICIENT FOR ITS DOWN-REGULATION FROM THE CELL-SURFACE BY HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 NEF (VOL 68, PG 3095, 1994)
ANDERSEN, SJ; LENBURG, M; LANDAU, NR; GARCIA, JV
1994 JUL ;68(7):4705-4705, Journal of virology
— id: 52430, year: 1994, vol: 68, page: 4705, stat: Journal Article,

The cytoplasmic domain of CD4 is sufficient for its down-regulation from the cell surface by human immunodeficiency virus type 1 Nef
Anderson SJ; Lenburg M; Landau NR; Garcia JV
1994 May;68(5):3092-3101, Journal of virology
— id: 57478, year: 1994, vol: 68, page: 3092, stat: Journal Article,

VPU AFFECTS THE ABILITY OF HIV-1 TO REPLICATE AND FORM SYNCYTIA IN CELLS EXPRESSING HIGH-LEVELS OF CD4
LANDAU, NR; LENBURG, ME; PAXTON, W
1993 MAR 29 ;43(4):50-50, Journal of cellular biochemistry
— id: 54213, year: 1993, vol: 43, page: 50, stat: Journal Article,

Vpu-induced degradation of CD4: requirement for specific amino acid residues in the cytoplasmic domain of CD4
Lenburg ME; Landau NR
1993 Dec;67(12):7238-7245, Journal of virology
— id: 56555, year: 1993, vol: 67, page: 7238, stat: Journal Article,

Incorporation of Vpr into human immunodeficiency virus type 1 virions: requirement for the p6 region of gag and mutational analysis
Paxton W; Connor RI; Landau NR
1993 Dec;67(12):7229-7237, Journal of virology
— id: 56571, year: 1993, vol: 67, page: 7229, stat: Journal Article,

Packaging system for rapid production of murine leukemia virus vectors with variable tropism
Landau NR; Littman DR
1992 Aug;66(8):5110-5113, Journal of virology
— id: 15154, year: 1992, vol: 66, page: 5110, stat: Journal Article,

Pseudotyping with human T-cell leukemia virus type I broadens the human immunodeficiency virus host range
Landau NR; Page KA; Littman DR
1991 Jan;65(1):162-169, Journal of virology
— id: 15166, year: 1991, vol: 65, page: 162, stat: Journal Article,

LyF-1, a transcriptional regulator that interacts with a novel class of promoters for lymphocyte-specific genes
Lo, K; Landau, N R; Smale, S T
1991 Oct;11(10):5229-5243, Molecular & cellular biology
— id: 68272, year: 1991, vol: 11, page: 5229, stat: Journal Article,

BCR first exon sequences specifically activate the BCR/ABL tyrosine kinase oncogene of Philadelphia chromosome-positive human leukemias
Muller AJ; Young JC; Pendergast AM; Pondel M; Landau NR; Littman DR; Witte ON
1991 Apr;11(4):1785-1792, Molecular & cellular biology
— id: 15163, year: 1991, vol: 11, page: 1785, stat: Journal Article,

Construction and use of a human immunodeficiency virus vector for analysis of virus infectivity
Page KA; Landau NR; Littman DR
1990 Nov;64(11):5270-5276, Journal of virology
— id: 15168, year: 1990, vol: 64, page: 5270, stat: Journal Article,

The envelope glycoprotein of the human immunodeficiency virus binds to the immunoglobulin-like domain of CD4
Landau NR; Warton M; Littman DR
1988 Jul 14;334(6178):159-162, Nature
— id: 57528, year: 1988, vol: 334, page: 159, stat: Journal Article,

2',3'-Dideoxyadenosine is selectively toxic for TdT-positive cells
Spigelman, Z; Duff, R; Beardsley, G P; Broder, S; Cooney, D; Landau, N R; Mitsuya, H; Ullman, B; McCaffrey, R
1988 Jun;71(6):1601-1608, Blood
— id: 68273, year: 1988, vol: 71, page: 1601, stat: Journal Article,

Increased frequency of N-region insertion in a murine pre-B-cell line infected with a terminal deoxynucleotidyl transferase retroviral expression vector
Landau, N R; Schatz, D G; Rosa, M; Baltimore, D
1987 Sep;7(9):3237-3243, Molecular & cellular biology
— id: 68274, year: 1987, vol: 7, page: 3237, stat: Journal Article,

Measurement of terminal deoxynucleotidyl transferase mRNA in clinical samples: a new parameter in analysis of leukemia cells
Wolf, S C; Steinherz, P G; Landau, N R; Silverstone, A E
1987 Jul;25(3):259-269, American journal of hematology
— id: 68275, year: 1987, vol: 25, page: 259, stat: Journal Article,

The terminal deoxynucleotidyltransferase gene is located on human chromosome 10 (10q23----q24) and on mouse chromosome 19
Yang-Feng, T L; Landau, N R; Baltimore, D; Francke, U
1986 ;43(3-4):121-126, Cytogenetics & cell genetics
— id: 68276, year: 1986, vol: 43, page: 121, stat: Journal Article,

Cloning of terminal transferase cDNA by antibody screening
Landau, N R; St John, T P; Weissman, I L; Wolf, S C; Silverstone, A E; Baltimore, D
1984 Sep;81(18):5836-5840, Proceedings of the National Academy of Sciences of the United States of America
— id: 68277, year: 1984, vol: 81, page: 5836, stat: Journal Article,