Michelle Krogsgaard

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Michelle Krogsgaard, Ph.D.

Assistant Professor;
Departments of Pathology and Perlmutter Cancer Center (Research-Fac)

Contact Info

Address
522 First Ave
Floor 13th floor Room 1311
Smilow Research Building
New York, NY 10016

(212)-263-9250
Michelle.Krogsgaard@nyumc.org

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Education

1996-1999 — University of Copenhagen, Graduate Education
1999-2002 — Stanford University SoM, PostDoctoral Training

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All data from NYU Health Sciences Library Faculty Bibliography — -

Contact:
http://hsl.med.nyu.edu/faculty-bibliography-search

TCR Microclusters Pre-Exist and Contain Molecules Necessary for TCR Signal Transduction
Crites, Travis J; Padhan, Kartika; Muller, James; Krogsgaard, Michelle; Gudla, Prabhakar R; Lockett, Stephen J; Varma, Rajat
2014 Jul;193(1):56-67, Journal of immunology
— id: 1051812, year: 2014, vol: 193, page: 56, stat: Journal Article,

Imprinting of the mature T cell response by self
Krogsgaard, Michelle
2014 Apr;35(4):141-143, Trends in immunology
— id: 883542, year: 2014, vol: 35, page: 141, stat: Journal Article,

2D TCR-pMHC-CD8 kinetics determines T-cell responses in a self-antigen-specific TCR system
Liu, Baoyu; Zhong, Shi; Malecek, Karolina; Johnson, Laura A; Rosenberg, Steven A; Zhu, Cheng; Krogsgaard, Michelle
2014 Jan;44(1):239-250, European journal of immunology
— id: 782802, year: 2014, vol: 44, page: 239, stat: Journal Article,

Specific Increase in Potency via Structure-Based Design of a TCR
Malecek, Karolina; Grigoryan, Arsen; Zhong, Shi; Gu, Wei Jun; Johnson, Laura A; Rosenberg, Steven A; Cardozo, Timothy; Krogsgaard, Michelle
2014 Jul;:2587-2599 CD004345, Journal of immunology
— id: 1089952, year: 2014, vol: , page: 2587, stat: Journal Article,

Quantitative analysis of T cell receptor complex interaction sites using genetically encoded photo-cross-linkers
Wang, Wenjuan; Li, Tianqi; Felsovalyi, Klara; Chen, Chunlai; Cardozo, Timothy; Krogsgaard, Michelle
2014 Sep;9(9):2165-2172, ACS chemical biology
— id: 1252232, year: 2014, vol: 9, page: 2165, stat: Journal Article,

Vitellogenin recognizes cell damage through membrane binding and shields living cells from reactive oxygen species
Havukainen, Heli; Munch, Daniel; Baumann, Anne; Zhong, Shi; Halskau, Oyvind; Krogsgaard, Michelle; Amdam, Gro V
2013 Sep;288(39):28369-28381, Journal of biological chemistry
— id: 932712, year: 2013, vol: 288, page: 28369, stat: Journal Article,

Engineering improved T cell receptors using an alanine-scan guided T cell display selection system
Malecek, Karolina; Zhong, Shi; McGary, Katelyn; Yu, Connie; Huang, Kevin; Johnson, Laura A; Rosenberg, Steven A; Krogsgaard, Michelle
2013 Jun;392(1-2):1-11, Journal of immunological methods
— id: 315962, year: 2013, vol: 392, page: 1, stat: Journal Article,

Correction: Probing the Effector and Suppressive Functions of Human T Cell Subsets Using Antigen-Specific Engineered T Cell Receptors
Wan, Qi; Kozhaya, Lina; Imberg, Keren; Mercer, Frances; Zhong, Shi; Krogsgaard, Michelle; Unutmaz, Derya
2013 ;8(10):?-?, PLoS one
— id: 908422, year: 2013, vol: 8, page: ?, stat: Journal Article,

Probing the effector and suppressive functions of human T cell subsets using antigen-specific engineered T cell receptors
Wan, Qi; Kozhaya, Lina; Imberg, Keren; Mercer, Frances; Zhong, Shi; Krogsgaard, Michelle; Unutmaz, Derya
2013 ;8(2):e56302-e56302 e56302, PLoS one
— id: 287192, year: 2013, vol: 8, page: e56302, stat: Journal Article,

Strength of PD-1 signaling differentially affects T-cell effector functions
Wei, Fang; Zhong, Shi; Ma, Zhengyu; Kong, Hong; Medvec, Andrew; Ahmed, Rafi; Freeman, Gordon J; Krogsgaard, Michelle; Riley, James L
2013 Apr;:E2480-E2489 e56302, Proceedings of the National Academy of Sciences of the United States of America
— id: 377372, year: 2013, vol: , page: E2480, stat: Journal Article,

T-cell receptor affinity and avidity defines antitumor response and autoimmunity in T-cell immunotherapy
Zhong, Shi; Malecek, Karolina; Johnson, Laura A; Yu, Zhiya; Vega-Saenz de Miera, Eleazar; Darvishian, Farbod; McGary, Katelyn; Huang, Kevin; Boyer, Josh; Corse, Emily; Shao, Yongzhao; Rosenberg, Steven A; Restifo, Nicholas P; Osman, Iman; Krogsgaard, Michelle
2013 Apr;110(17):6973-6978, Proceedings of the National Academy of Sciences of the United States of America
— id: 304932, year: 2013, vol: 110, page: 6973, stat: Journal Article,

TILs in metastatic melanoma tumors: A biomarker for immunotherapy?
Chandra, S; Ding, Y; Ma, M W; Bannan, M; Darvishian, F; Berman, R S; Shapiro, R; Krogsgaard, M; Osman, I; Pavlick, A C
2012 20 May 2012;30(15):-, Journal of clinical oncology
— id: 249972, year: 2012, vol: 30, page: , stat: Journal Article,

Mage-a3 specific t-cell receptor adoptive cell transfer of multiple myeloma
Park, J; Zhong, S; Krogsgaard, M; Mazumder, A
2012 16 Nov 2012;:-, Blood
— id: 217022, year: 2012, vol: , page: , stat: Journal Article,

Attenuated T cell responses to a high-potency ligand in vivo. L
Corse, Emily; Gottschalk, Rachel A; Krogsgaard, Michelle; Allison, James P
2010 ;8(9):?-?, PLoS biology
— id: 112589, year: 2010, vol: 8, page: ?, stat: Journal Article,

Peptide-MHC heterodimers show that thymic positive selection requires a more restricted set of self-peptides than negative selection
Juang, Jeremy; Ebert, Peter J R; Feng, Dan; Garcia, K Christopher; Krogsgaard, Michelle; Davis, Mark M
2010 Jun 7;207(6):1223-1234, Journal of experimental medicine
— id: 109693, year: 2010, vol: 207, page: 1223, stat: Journal Article,

Polyreactivity increases the apparent affinity of anti-HIV antibodies by heteroligation
Mouquet, Hugo; Scheid, Johannes F; Zoller, Markus J; Krogsgaard, Michelle; Ott, Rene G; Shukair, Shetha; Artyomov, Maxim N; Pietzsch, John; Connors, Mark; Pereyra, Florencia; Walker, Bruce D; Ho, David D; Wilson, Patrick C; Seaman, Michael S; Eisen, Herman N; Chakraborty, Arup K; Hope, Thomas J; Ravetch, Jeffrey V; Wardemann, Hedda; Nussenzweig, Michel C
2010 Sep 30;467(7315):591-595, Nature
— id: 113743, year: 2010, vol: 467, page: 591, stat: Journal Article,

Retroviral transduction of T-cell receptors in mouse T-cells
Zhong, Shi; Malecek, Karolina; Perez-Garcia, Arianne; Krogsgaard, Michelle
2010 ;(44):?-? e56302, Journal of visualized experiments : JoVE
— id: 377362, year: 2010, vol: , page: ?, stat: Journal Article,

In vivo enhancement of peptide display by MHC class II molecules with small molecule catalysts of peptide exchange
Call, Melissa J; Xing, Xuechao; Cuny, Gregory D; Seth, Nilufer P; Altmann, Daniel M; Fugger, Lars; Krogsgaard, Michelle; Stein, Ross L; Wucherpfennig, Kai W
2009 May;182(10):6342-6352, Journal of immunology
— id: 377382, year: 2009, vol: 182, page: 6342, stat: Journal Article,

Developing a multidisciplinary prospective melanoma biospecimen repository to advance translational research
Wich, Lindsay G; Hamilton, Heather K; Shapiro, Richard L; Pavlick, Anna; Berman, Russell S; Polsky, David; Goldberg, Judith D; Hernando, Eva; Manga, Prashiela; Krogsgaard, Michelle; Kamino, Hideko; Darvishian, Farbod; Lee, Peng; Orlow, Seth J; Ostrer, Harry; Bhardwaj, Nina; Osman, Iman
2009 ;1(1):35-43, American journal of translational research
— id: 105566, year: 2009, vol: 1, page: 35, stat: Journal Article,

T Cells as a Self-Referential, Sensory Organ
Davis, Mark M; Krogsgaard, Michelle; Huse, Morgan; Huppa, Johannes; Lillemeier, Bjoern F; Li, Qi-jing
2007 Apr 23;25:681-695, Annual review of immunology
— id: 71174, year: 2007, vol: 25, page: 681, stat: Journal Article,

A role for "self" in T-cell activation
Krogsgaard, Michelle; Juang, Jeremy; Davis, Mark M
2007 Aug;19(4):236-244, Seminars in immunology
— id: 73008, year: 2007, vol: 19, page: 236, stat: Journal Article,

The effect of protein and carbohydrate supplementation on strength training outcome of rehabilitation in ACL patients
Holm, L; Esmarck, B; Mizuno, M; Hansen, H; Suetta, C; Holmich, P; Krogsgaard, M; Kjaer, M
2006 Nov;24(11):2114-2123, Journal of orthopaedic research
— id: 377712, year: 2006, vol: 24, page: 2114, stat: Journal Article,

Molecular flexibility can influence the stimulatory ability of receptor-ligand interactions at cell-cell junctions
Qi, Shuyan; Krogsgaard, Michelle; Davis, Mark M; Chakraborty, Arup K
2006 Mar 21;103(12):4416-4421, Proceedings of the National Academy of Sciences of the United States of America
— id: 64531, year: 2006, vol: 103, page: 4416, stat: Journal Article,

Quantitative imaging of lymphocyte membrane protein reorganization and signaling
Kasson, Peter M; Huppa, Johannes B; Krogsgaard, Michelle; Davis, Mark M; Brunger, Axel T
2005 Jan;88(1):579-589, Biophysical journal
— id: 62707, year: 2005, vol: 88, page: 579, stat: Journal Article,

How T cells 'see' antigen
Krogsgaard, Michelle; Davis, Mark M
2005 Mar;6(3):239-245, Nature immunology
— id: 62706, year: 2005, vol: 6, page: 239, stat: Journal Article,

Agonist/endogenous peptide-MHC heterodimers drive T cell activation and sensitivity
Krogsgaard, Michelle; Li, Qi-Jing; Sumen, Cenk; Huppa, Johannes B; Huse, Morgan; Davis, Mark M
2005 Mar 10;434(7030):238-243, Nature
— id: 62705, year: 2005, vol: 434, page: 238, stat: Journal Article,

High-level bacterial secretion of single-chain alphabeta T-cell receptors
Maynard, Jennifer; Adams, Erin J; Krogsgaard, Michelle; Petersson, Karin; Liu, Corey W; Garcia, K Christopher
2005 Nov 30;306(1-2):51-67, Journal of immunological methods
— id: 62703, year: 2005, vol: 306, page: 51, stat: Journal Article,

Selection of aberrant class II restricted CD8+ T cells in NOD mice expressing a glutamic acid decarboxylase (GAD)65-specific T cell receptor transgene
Ranheim, Erik A; Tarbell, Kristin V; Krogsgaard, Michelle; Mallet-Designe, Valerie; Teyton, Luc; McDevitt, Hugh O; Weissman, Irving L
2004 Dec;37(8):555-567, Autoimmunity
— id: 62704, year: 2004, vol: 37, page: 555, stat: Journal Article,

Distinct molecular mechanisms account for the specificity of two different T-cell receptors
Anikeeva, Nadja; Lebedeva, Tatiana; Krogsgaard, Michelle; Tetin, Sergey Y; Martinez-Hackert, Erik; Kalams, Spyros A; Davis, Mark M; Sykulev, Yuri
2003 Apr 29;42(16):4709-4716, Biochemistry
— id: 62711, year: 2003, vol: 42, page: 4709, stat: Journal Article,

Dynamics of cell surface molecules during T cell recognition
Davis, Mark M; Krogsgaard, Michelle; Huppa, Johannes B; Sumen, Cenk; Purbhoo, Marco A; Irvine, Darrell J; Wu, Lawren C; Ehrlich, Lauren
2003 ;72:717-742, Annual review of biochemistry
— id: 62710, year: 2003, vol: 72, page: 717, stat: Journal Article,

Linking molecular and cellular events in T-cell activation and synapse formation
Krogsgaard, Michelle; Huppa, Johannes B; Purbhoo, Marco A; Davis, Mark M
2003 Dec;15(6):307-315, Seminars in immunology
— id: 62708, year: 2003, vol: 15, page: 307, stat: Journal Article,

Evidence that structural rearrangements and/or flexibility during TCR binding can contribute to T cell activation
Krogsgaard, Michelle; Prado, Nelida; Adams, Erin J; He, Xiao-lin; Chow, Dar-Chone; Wilson, Darcy B; Garcia, K Christopher; Davis, Mark M
2003 Dec;12(6):1367-1378, Molecular cell
— id: 62709, year: 2003, vol: 12, page: 1367, stat: Journal Article,

Direct observation of ligand recognition by T cells
Irvine, Darrell J; Purbhoo, Marco A; Krogsgaard, Michelle; Davis, Mark M
2002 Oct 24;419(6909):845-849, Nature
— id: 62712, year: 2002, vol: 419, page: 845, stat: Journal Article,

Phage-display libraries of murine and human anitbody fab fragments
Engberg J; Johansen LK; Westengaard-Hildinge M; Riise ES; Albrechtsen B
The Nucleic acid protocols handbook Totowa NJ : Humana Press, 2000,
— id: 4013, year: 2000, vol: , page: 449, stat: Chapter,

Visualization of myelin basic protein (MBP) T cell epitopes in multiple sclerosis lesions using a monoclonal antibody specific for the human histocompatibility leukocyte antigen (HLA)-DR2-MBP 85-99 complex
Krogsgaard M; Wucherpfennig KW; Cannella B; Hansen BE; Svejgaard A; Pyrdol J; Ditzel H; Raine C; Engberg J; Fugger L
2000 Apr 17;191(8):1395-1412, Journal of experimental medicine
— id: 64532, year: 2000, vol: 191, page: 1395, stat: Journal Article,

Recombinant antibodies with the antigen-specific, MHC restricted specificity of T cells: novel reagents for basic and clinical investigations and immunotherapy
Engberg J; Krogsgaard M; Fugger L
1999 Mar;4(3-4):273-278, Immunotechnology
— id: 64534, year: 1999, vol: 4, page: 273, stat: Journal Article,

A humanized model for multiple sclerosis using HLA-DR2 and a human T-cell receptor
Madsen LS; Andersson EC; Jansson L; krogsgaard M; Andersen CB; Engberg J; Strominger JL; Svejgaard A; Hjorth JP; Holmdahl R; Wucherpfennig KW; Fugger L
1999 Nov;23(3):343-347, Nature genetics
— id: 64533, year: 1999, vol: 23, page: 343, stat: Journal Article,