Tomas Kirchhoff

Biosketch / Results /

Tomas Kirchhoff, Ph.D.

Assistant Professor;
Departments of Population Health and Environmental Medicine

Contact Info

Address
522 First Avenue
Floor 12 Room 1206
Smilow Research Building
New York, NY 10016

212-263-9473
Tomas.Kirchhoff@nyumc.org

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Research Summary

The primary interest of my laboratory is focused on the identification of the genetic basis of cancer susceptibility. A key question in these efforts is how the germline genetic events contributing to predisposition of human cancers interact mutually in particular molecular pathways or in concert with the environmental exposures. Specifically, our ongoing studies aim at identification of the genetic variants conferring an increased risk to common cancers, such as breast, colon, prostate cancers or lymphoma, focusing on the relevant molecular pathways. These studies combine the genome-wide association analysis (GWAS), high-throughput genotyping and most recently the next-generation sequencing in large case/control populations. The significant aspect of my current and future research is an integration of the information from somatic genetics in tumors to complement the germline findings. We believe that such integration of biological data will be beneficial not only for improved prevention strategies but most importantly for the future development of the targeted personalized therapies.

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All data from NYU Health Sciences Library Faculty Bibliography — -

Contact:
http://hsl.med.nyu.edu/faculty-bibliography-search

PP6C Hotspot Mutations in Melanoma Display Sensitivity to Aurora Kinase Inhibition
Gold, Heidi L; Wengrod, Jordan; de Miera, Eleazar Vega-Saenz; Wang, Ding; Fleming, Nathaniel; Sikkema, Lisa; Kirchhoff, Tomas; Hochman, Tsivia; Goldberg, Judith D; Osman, Iman; Gardner, Lawrence B
2014 Mar;12(3):433-439, Molecular cancer research
— id: 883502, year: 2014, vol: 12, page: 433, stat: Journal Article,

Genetic Variation in DNA Repair Pathways and Risk of Non-Hodgkin's Lymphoma
Rendleman, Justin; Antipin, Yevgeniy; Reva, Boris; Adaniel, Christina; Przybylo, Jennifer A; Dutra-Clarke, Ana; Hansen, Nichole; Heguy, Adriana; Huberman, Kety; Borsu, Laetitia; Paltiel, Ora; Ben-Yehuda, Dina; Brown, Jennifer R; Freedman, Arnold S; Sander, Chris; Zelenetz, Andrew; Klein, Robert J; Shao, Yongzhao; Lacher, Mortimer; Vijai, Joseph; Offit, Kenneth; Kirchhoff, Tomas
2014 ;9(7):e101685-e101685 e101685, PLoS one
— id: 1074882, year: 2014, vol: 9, page: e101685, stat: Journal Article,

Introduction to epidemiology of breast and ovarian cancers
Adaniel, C; Kirchhoff, T
2013 Nov;24 Suppl 8:viii61-viii62, Annals of oncology
— id: 598502, year: 2013, vol: 24 Suppl 8, page: viii61, stat: Journal Article,

Breast cancer risk prediction using the novel germ-line signatures in epigenome regulatory pathways
Adaniel, C; Rendleman, J; Smith, J A; Klein, R J; Schnabel, F R; Shao, Y; Offit, K; Kirchhoff, T
2013 20 May 2013;31(15):-, Journal of clinical oncology
— id: 452002, year: 2013, vol: 31, page: , stat: Journal Article,

Identification of a BRCA2-specific modifier locus at 6p24 related to breast cancer risk
Gaudet, Mia M; Kuchenbaecker, Karoline B; Vijai, Joseph; Klein, Robert J; Kirchhoff, Tomas; McGuffog, Lesley; Barrowdale, Daniel; Dunning, Alison M; Lee, Andrew; Dennis, Joe; Healey, Sue; Dicks, Ed; Soucy, Penny; Sinilnikova, Olga M; Pankratz, Vernon S; Wang, Xianshu; Eldridge, Ronald C; Tessier, Daniel C; Vincent, Daniel; Bacot, Francois; Hogervorst, Frans B L; Peock, Susan; Stoppa-Lyonnet, Dominique; Peterlongo, Paolo; Schmutzler, Rita K; Nathanson, Katherine L; Piedmonte, Marion; Singer, Christian F; Thomassen, Mads; Hansen, Thomas v O; Neuhausen, Susan L; Blanco, Ignacio; Greene, Mark H; Garber, Judith; Weitzel, Jeffrey N; Andrulis, Irene L; Goldgar, David E; D'Andrea, Emma; Caldes, Trinidad; Nevanlinna, Heli; Osorio, Ana; van Rensburg, Elizabeth J; Arason, Adalgeir; Rennert, Gad; van den Ouweland, Ans M W; van der Hout, Annemarie H; Kets, Carolien M; Aalfs, Cora M; Wijnen, Juul T; Ausems, Margreet G E M; Frost, Debra; Ellis, Steve; Fineberg, Elena; Platte, Radka; Evans, D Gareth; Jacobs, Chris; Adlard, Julian; Tischkowitz, Marc; Porteous, Mary E; Damiola, Francesca; Golmard, Lisa; Barjhoux, Laure; Longy, Michel; Belotti, Muriel; Ferrer, Sandra Fert; Mazoyer, Sylvie; Spurdle, Amanda B; Manoukian, Siranoush; Barile, Monica; Genuardi, Maurizio; Arnold, Norbert; Meindl, Alfons; Sutter, Christian; Wappenschmidt, Barbara; Domchek, Susan M; Pfeiler, Georg; Friedman, Eitan; Jensen, Uffe Birk; Robson, Mark; Shah, Sohela; Lazaro, Conxi; Mai, Phuong L; Benitez, Javier; Southey, Melissa C; Schmidt, Marjanka K; Fasching, Peter A; Peto, Julian; Humphreys, Manjeet K; Wang, Qin; Michailidou, Kyriaki; Sawyer, Elinor J; Burwinkel, Barbara; Guenel, Pascal; Bojesen, Stig E; Milne, Roger L; Brenner, Hermann; Lochmann, Magdalena; Aittomaki, Kristiina; Dork, Thilo; Margolin, Sara; Mannermaa, Arto; Lambrechts, Diether; Chang-Claude, Jenny; Radice, Paolo; Giles, Graham G; Haiman, Christopher A; Winqvist, Robert; Devillee, Peter; Garcia-Closas, Montserrat; Schoof, Nils; Hooning, Maartje J; Cox, Angela; Pharoah, Paul D P; Jakubowska, Anna; Orr, Nick; Gonzalez-Neira, Anna; Pita, Guillermo; Alonso, M Rosario; Hall, Per; Couch, Fergus J; Simard, Jacques; Altshuler, David; Easton, Douglas F; Chenevix-Trench, Georgia; Antoniou, Antonis C; Offit, Kenneth
2013 Mar;9(3):e1003173-e1003173 e1003173, PLoS genetics
— id: 335212, year: 2013, vol: 9, page: e1003173, stat: Journal Article,

Extended replication of a GWAS for breast cancer in BRCA2 mutation carriers
Kuchenbaecker, K B; Gaudet, M M; Vijai, J; Klein, R J; Kirchhoff, T; McGuffog, L; Barrowdale, D; Dunning, A M; Lee, A; Hall, P; Couch, F J; Simard, J; Altshuler, D; Easton, D F; Chenevix-Trench, G; Antoniou, A C; Offit, K
2013 March 2013;25(1):106-106, Medizinische genetik
— id: 250322, year: 2013, vol: 25, page: 106, stat: Journal Article,

Genetic variation in immunomodulatory genes as markers of melanoma recurrence-free and overall survival
Rendleman, J; Shang, S; Shields, J; Adaniel, C; Fleming, N H; Shapiro, R; Berman, R S; Pavlick, A C; Shao, Y; Osman, I; Kirchhoff, T
2013 20 May 2013;31(15):-, Journal of clinical oncology
— id: 451922, year: 2013, vol: 31, page: , stat: Journal Article,

Melanoma risk loci as determinants of melanoma recurrence and survival
Rendleman, Justin; Shang, Shulian; Dominianni, Christine; Shields, Jerry F; Scanlon, Patrick; Adaniel, Christina; Desrichard, Alexis; Ma, Michelle; Shapiro, Richard; Berman, Russell; Pavlick, Anna; Polsky, David; Shao, Yongzhao; Osman, Iman; Kirchhoff, Tomas
2013 Nov;11(1):279-279, Journal of translational medicine
— id: 617512, year: 2013, vol: 11, page: 279, stat: Journal Article,

Assessment of Mutations in Hereditary Breast Cancers
Shah, Sohela; Kim, Yonghwan; Ostrovnaya, Irina; Murali, Rajmohan; Schrader, Kasmintan A; Lach, Francis P; Sarrel, Kara; Rau-Murthy, Rohini; Hansen, Nichole; Zhang, Liyng; Kirchhoff, Tomas; Stadler, Zsofia; Robson, Mark; Vijai, Joseph; Offit, Kenneth; Smogorzewska, Agata
2013 ;8(6):e66961-e66961 e66961, PLoS one
— id: 922312, year: 2013, vol: 8, page: e66961, stat: Journal Article,

Susceptibility loci associated with specific and shared subtypes of lymphoid malignancies
Vijai, Joseph; Kirchhoff, Tomas; Schrader, Kasmintan A; Brown, Jennifer; Dutra-Clarke, Ana Virginia; Manschreck, Christopher; Hansen, Nichole; Rau-Murthy, Rohini; Sarrel, Kara; Przybylo, Jennifer; Shah, Sohela; Cheguri, Srujana; Stadler, Zsofia; Zhang, Liying; Paltiel, Ora; Ben-Yehuda, Dina; Viale, Agnes; Portlock, Carol; Straus, David; Lipkin, Steven M; Lacher, Mortimer; Robson, Mark; Klein, Robert J; Zelenetz, Andrew; Offit, Kenneth
2013 Jan;9(1):e1003220-e1003220 e1003220, PLoS genetics
— id: 232712, year: 2013, vol: 9, page: e1003220, stat: Journal Article,

Common variants at 12p11, 12q24, 9p21, 9q31.2 and in ZNF365 are associated with breast cancer risk for BRCA1 and/or BRCA2 mutation carriers
Antoniou, Antonis C; Kuchenbaecker, Karoline B; Soucy, Penny; Beesley, Jonathan; Chen, Xiaoqing; McGuffog, Lesley; Lee, Andrew; Barrowdale, Daniel; Healey, Sue; Sinilnikova, Olga M; Caligo, Maria A; Loman, Niklas; Harbst, Katja; Lindblom, Annika; Arver, Brita; Rosenquist, Richard; Karlsson, Per; Nathanson, Kate; Domchek, Susan; Rebbeck, Tim; Jakubowska, Anna; Lubinski, Jan; Jaworska, Katarzyna; Durda, Katarzyna; Zlowowcka-Perlowska, Elzbieta; Osorio, Ana; Duran, Mercedes; Andres, Raquel; Benitez, Javier; Hamann, Ute; Hogervorst, Frans B; van Os, Theo A; Verhoef, Senno; Meijers-Heijboer, Hanne E J; Wijnen, Juul; Gomez Garcia, Encarna B; Ligtenberg, Marjolijn J; Kriege, Mieke; Collee, J Margriet; Ausems, Margreet G E M; Oosterwijk, Jan C; Peock, Susan; Frost, Debra; Ellis, Steve D; Platte, Radka; Fineberg, Elena; Evans, D Gareth; Lalloo, Fiona; Jacobs, Chris; Eeles, Ros; Adlard, Julian; Davidson, Rosemarie; Cole, Trevor; Cook, Jackie; Paterson, Joan; Douglas, Fiona; Brewer, Carole; Hodgson, Shirley; Morrison, Patrick J; Walker, Lisa; Rogers, Mark T; Donaldson, Alan; Dorkins, Huw; Godwin, Andrew K; Bove, Betsy; Stoppa-Lyonnet, Dominique; Houdayer, Claude; Buecher, Bruno; de Pauw, Antoine; Mazoyer, Sylvie; Calender, Alain; Leone, Melanie; Bressac-de Paillerets, Brigitte; Caron, Olivier; Sobol, Hagay; Frenay, Marc; Prieur, Fabienne; Ferrer, Sandra U; Mortemousque, Isabelle; Buys, Saundra; Daly, Mary; Miron, Alexander; Terry, Mary U; Hopper, John L; John, Esther M; Southey, Melissa; Goldgar, David; Singer, Christian F; Fink-Retter, Anneliese; Tea, Muy-Kheng; Kaulich, Daphne U; Hansen, Thomas V; Nielsen, Finn C; Barkardottir, Rosa B; Gaudet, Mia; Kirchhoff, Tomas; Joseph, Vijai; Dutra-Clarke, Ana; Offit, Kenneth; Piedmonte, Marion; Kirk, Judy; Cohn, David; Hurteau, Jean; Byron, John; Fiorica, James; Toland, Amanda E; Montagna, Marco; Oliani, Cristina; Imyanitov, Evgeny; Isaacs, Claudine; Tihomirova, Laima; Blanco, Ignacio; Lazaro, Conxi; Teule, Alex; Valle, J Del; Gayther, Simon A; Odunsi, Kunle; Gross, Jenny; Karlan, Beth Y; Olah, Edith; Teo, Soo-Hwang; Ganz, Patricia A; Beattie, Mary S; Dorfling, Cecelia M; van Rensburg, Elizabeth U; Diez, Orland; Kwong, Ava; Schmutzler, Rita K; Wappenschmidt, Barbara; Engel, Christoph; Meindl, Alfons; Ditsch, Nina; Arnold, Norbert; Heidemann, Simone; Niederacher, Dieter; Preisler-Adams, Sabine; Gadzicki, Dorothea; Varon-Mateeva, Raymonda; Deissler, Helmut; Gehrig, Andrea; Sutter, Christian; Kast, Karin; Fiebig, Britta; Schafer, Dieter; Caldes, Trinidad; de la Hoya, Miguel; Nevanlinna, Heli; Muranen, Taru A; Lesperance, Bernard; Spurdle, Amanda B; Neuhausen, Susan L; Ding, Yuan C; Wang, Xianshu; Fredericksen, Zachary; Pankratz, Vernon S; Lindor, Noralane M; Peterlongo, Paolo; Manoukian, Siranoush; Peissel, Bernard; Zaffaroni, Daniela; Bonanni, Bernardo; Bernard, Loris; Dolcetti, Riccardo; Papi, Laura; Ottini, Laura; Radice, Paolo; Greene, Mark H; Loud, Jennifer T; Andrulis, Irene L; Ozcelik, Hilmi; Mulligan, Anna U; Glendon, Gord; Thomassen, Mads; Gerdes, Anne-Marie; Jensen, Uffe B; Skytte, Anne-Bine; Kruse, Torben A; Chenevix-Trench, Georgia; Couch, Fergus J; Simard, Jacques; Easton, Douglas F
2012 ;14(1):R33-R33 R33, Breast cancer research
— id: 232742, year: 2012, vol: 14, page: R33, stat: Journal Article,

Common variants at the 19p13.1 and ZNF365 loci are associated with ER subtypes of breast cancer and ovarian cancer risk in BRCA1 and BRCA2 mutation carriers
Couch, Fergus J; Gaudet, Mia M; Antoniou, Antonis C; Ramus, Susan J; Kuchenbaecker, Karoline B; Soucy, Penny; Beesley, Jonathan; Chen, Xiaoqing; Wang, Xianshu; Kirchhoff, Tomas; McGuffog, Lesley; Barrowdale, Daniel; Lee, Andrew; Healey, Sue; Sinilnikova, Olga M; Andrulis, Irene L; Ozcelik, Hilmi; Mulligan, Anna Marie; Thomassen, Mads; Gerdes, Anne-Marie; Jensen, Uffe Birk; Skytte, Anne-Bine; Kruse, Torben A; Caligo, Maria A; von Wachenfeldt, Anna; Barbany-Bustinza, Gisela; Loman, Niklas; Soller, Maria; Ehrencrona, Hans; Karlsson, Per; Nathanson, Katherine L; Rebbeck, Timothy R; Domchek, Susan M; Jakubowska, Ania; Lubinski, Jan; Jaworska, Katarzyna; Durda, Katarzyna; Zlowocka, Elzbieta; Huzarski, Tomasz; Byrski, Tomasz; Gronwald, Jacek; Cybulski, Cezary; Gorski, Bohdan; Osorio, Ana; Duran, Mercedes; Tejada, Maria Isabel; Benitez, Javier; Hamann, Ute; Hogervorst, Frans B L; van Os, Theo A; van Leeuwen, Flora E; Meijers-Heijboer, Hanne E J; Wijnen, Juul; Blok, Marinus J; Kets, Marleen; Hooning, Maartje J; Oldenburg, Rogier A; Ausems, Margreet G E M; Peock, Susan; Frost, Debra; Ellis, Steve D; Platte, Radka; Fineberg, Elena; Evans, D Gareth; Jacobs, Chris; Eeles, Rosalind A; Adlard, Julian; Davidson, Rosemarie; Eccles, Diana M; Cole, Trevor; Cook, Jackie; Paterson, Joan; Brewer, Carole; Douglas, Fiona; Hodgson, Shirley V; Morrison, Patrick J; Walker, Lisa; Porteous, Mary E; Kennedy, M John; Side, Lucy E; Bove, Betsy; Godwin, Andrew K; Stoppa-Lyonnet, Dominique; Fassy-Colcombet, Marion; Castera, Laurent; Cornelis, Francois; Mazoyer, Sylvie; Leone, Melanie; Boutry-Kryza, Nadia; Bressac-de Paillerets, Brigitte; Caron, Olivier; Pujol, Pascal; Coupier, Isabelle; Delnatte, Capucine; Akloul, Linda; Lynch, Henry T; Snyder, Carrie L; Buys, Saundra S; Daly, Mary B; Terry, Marybeth; Chung, Wendy K; John, Esther M; Miron, Alexander; Southey, Melissa C; Hopper, John L; Goldgar, David E; Singer, Christian F; Rappaport, Christine; Tea, Muy-Kheng M; Fink-Retter, Anneliese; Hansen, Thomas V O; Nielsen, Finn C; Arason, Aethalgeir; Vijai, Joseph; Shah, Sohela; Sarrel, Kara; Robson, Mark E; Piedmonte, Marion; Phillips, Kelly; Basil, Jack; Rubinstein, Wendy S; Boggess, John; Wakeley, Katie; Ewart-Toland, Amanda; Montagna, Marco; Agata, Simona; Imyanitov, Evgeny N; Isaacs, Claudine; Janavicius, Ramunas; Lazaro, Conxi; Blanco, Ignacio; Feliubadalo, Lidia; Brunet, Joan; Gayther, Simon A; Pharoah, Paul P D; Odunsi, Kunle O; Karlan, Beth Y; Walsh, Christine S; Olah, Edith; Teo, Soo Hwang; Ganz, Patricia A; Beattie, Mary S; van Rensburg, Elizabeth J; Dorfling, Cecelia M; Diez, Orland; Kwong, Ava; Schmutzler, Rita K; Wappenschmidt, Barbara; Engel, Christoph; Meindl, Alfons; Ditsch, Nina; Arnold, Norbert; Heidemann, Simone; Niederacher, Dieter; Preisler-Adams, Sabine; Gadzicki, Dorothea; Varon-Mateeva, Raymonda; Deissler, Helmut; Gehrig, Andrea; Sutter, Christian; Kast, Karin; Fiebig, Britta; Heinritz, Wolfram; Caldes, Trinidad; de la Hoya, Miguel; Muranen, Taru A; Nevanlinna, Heli; Tischkowitz, Marc D; Spurdle, Amanda B; Neuhausen, Susan L; Ding, Yuan Chun; Lindor, Noralane M; Fredericksen, Zachary; Pankratz, V Shane; Peterlongo, Paolo; Manoukian, Siranoush; Peissel, Bernard; Zaffaroni, Daniela; Barile, Monica; Bernard, Loris; Viel, Alessandra; Giannini, Giuseppe; Varesco, Liliana; Radice, Paolo; Greene, Mark H; Mai, Phuong L; Easton, Douglas F; Chenevix-Trench, Georgia; Offit, Kenneth; Simard, Jacques
2012 Apr;21(4):645-657, Cancer epidemiology biomarkers & prevention
— id: 232732, year: 2012, vol: 21, page: 645, stat: Journal Article,

Breast cancer risk and 6q22.33: combined results from Breast Cancer Association Consortium and Consortium of Investigators on Modifiers of BRCA1/2
Kirchhoff, Tomas; Gaudet, Mia M; Antoniou, Antonis C; McGuffog, Lesley; Humphreys, Manjeet K; Dunning, Alison M; Bojesen, Stig E; Nordestgaard, Borge G; Flyger, Henrik; Kang, Daehee; Yoo, Keun-Young; Noh, Dong-Young; Ahn, Sei-Hyun; Dork, Thilo; Schurmann, Peter; Karstens, Johann H; Hillemanns, Peter; Couch, Fergus J; Olson, Janet; Vachon, Celine; Wang, Xianshu; Cox, Angela; Brock, Ian; Elliott, Graeme; Reed, Malcolm W R; Burwinkel, Barbara; Meindl, Alfons; Brauch, Hiltrud; Hamann, Ute; Ko, Yon-Dschun; Broeks, Annegien; Schmidt, Marjanka K; Van 't Veer, Laura J; Braaf, Linde M; Johnson, Nichola; Fletcher, Olivia; Gibson, Lorna; Peto, Julian; Turnbull, Clare; Seal, Sheila; Renwick, Anthony; Rahman, Nazneen; Wu, Pei-Ei; Yu, Jyh-Cherng; Hsiung, Chia-Ni; Shen, Chen-Yang; Southey, Melissa C; Hopper, John L; Hammet, Fleur; Van Dorpe, Thijs; Dieudonne, Anne-Sophie; Hatse, Sigrid; Lambrechts, Diether; Andrulis, Irene L; Bogdanova, Natalia; Antonenkova, Natalia; Rogov, Juri I; Prokofieva, Daria; Bermisheva, Marina; Khusnutdinova, Elza; van Asperen, Christi J; Tollenaar, Robert A E M; Hooning, Maartje J; Devilee, Peter; Margolin, Sara; Lindblom, Annika; Milne, Roger L; Arias, Jose Ignacio; Zamora, M Pilar; Benitez, Javier; Severi, Gianluca; Baglietto, Laura; Giles, Graham G; Spurdle, Amanda B; Beesley, Jonathan; Chen, Xiaoqing; Holland, Helene; Healey, Sue; Wang-Gohrke, Shan; Chang-Claude, Jenny; Mannermaa, Arto; Kosma, Veli-Matti; Kauppinen, Jaana; Kataja, Vesa; Agnarsson, Bjarni A; Caligo, Maria A; Godwin, Andrew K; Nevanlinna, Heli; Heikkinen, Tuomas; Fredericksen, Zachary; Lindor, Noralane; Nathanson, Katherine L; Domchek, Susan M; Loman, Niklas; Karlsson, Per; Stenmark Askmalm, Marie; Melin, Beatrice; von Wachenfeldt, Anna; Hogervorst, Frans B L; Verheus, Martijn; Rookus, Matti A; Seynaeve, Caroline; Oldenburg, Rogier A; Ligtenberg, Marjolijn J; Ausems, Margreet G E M; Aalfs, Cora M; Gille, Hans J P; Wijnen, Juul T; Gomez Garcia, Encarna B; Peock, Susan; Cook, Margaret; Oliver, Clare T; Frost, Debra; Luccarini, Craig; Pichert, Gabriella; Davidson, Rosemarie; Chu, Carol; Eccles, Diana; Ong, Kai-Ren; Cook, Jackie; Douglas, Fiona; Hodgson, Shirley; Evans, D Gareth; Eeles, Rosalind; Gold, Bert; Pharoah, Paul D P; Offit, Kenneth; Chenevix-Trench, Georgia; Easton, Douglas F
2012 ;7(6):e35706-e35706 e35706, PLoS one
— id: 232722, year: 2012, vol: 7, page: e35706, stat: Journal Article,

The KL-VS sequence variant of Klotho and cancer risk in BRCA1 and BRCA2 mutation carriers
Laitman, Yael; Kuchenbaecker, Karoline B; Rantala, Johanna; Hogervorst, Frans; Peock, Susan; Godwin, Andrew K; Arason, Adalgeir; Kirchhoff, Tomas; Offit, Kenneth; Isaacs, Claudine; Schmutzler, Rita K; Wappenschmidt, Barbara; Nevanlinna, Heli; Chen, Xiaoqing; Chenevix-Trench, Georgia; Healey, Sue; Couch, Fergus; Peterlongo, Paolo; Radice, Paolo; Nathanson, Katherine L; Caligo, Maria Adelaide; Neuhausen, Susan L; Ganz, Patricia; Sinilnikova, Olga M; McGuffog, Lesley; Easton, Douglas F; Antoniou, Antonis C; Wolf, Ido; Friedman, Eitan
2012 Apr;132(3):1119-1126, Breast cancer research & treatment
— id: 167141, year: 2012, vol: 132, page: 1119, stat: Journal Article,

Ovarian cancer susceptibility alleles and risk of ovarian cancer in BRCA1 and BRCA2 mutation carriers
Ramus, Susan J; Antoniou, Antonis C; Kuchenbaecker, Karoline B; Soucy, Penny; Beesley, Jonathan; Chen, Xiaoqing; McGuffog, Lesley; Sinilnikova, Olga M; Healey, Sue; Barrowdale, Daniel; Lee, Andrew; Thomassen, Mads; Gerdes, Anne-Marie; Kruse, Torben A; Jensen, Uffe Birk; Skytte, Anne-Bine; Caligo, Maria A; Liljegren, Annelie; Lindblom, Annika; Olsson, Hakan; Kristoffersson, Ulf; Stenmark-Askmalm, Marie; Melin, Beatrice; Domchek, Susan M; Nathanson, Katherine L; Rebbeck, Timothy R; Jakubowska, Anna; Lubinski, Jan; Jaworska, Katarzyna; Durda, Katarzyna; Zlowocka, Elzbieta; Gronwald, Jacek; Huzarski, Tomasz; Byrski, Tomasz; Cybulski, Cezary; Toloczko-Grabarek, Aleksandra; Osorio, Ana; Benitez, Javier; Duran, Mercedes; Tejada, Maria-Isabel; Hamann, Ute; Rookus, Matti; van Leeuwen, Flora E; Aalfs, Cora M; Meijers-Heijboer, Hanne E J; van Asperen, Christi J; van Roozendaal, K E P; Hoogerbrugge, Nicoline; Collee, J Margriet; Kriege, Mieke; van der Luijt, Rob B; Peock, Susan; Frost, Debra; Ellis, Steve D; Platte, Radka; Fineberg, Elena; Evans, D Gareth; Lalloo, Fiona; Jacobs, Chris; Eeles, Ros; Adlard, Julian; Davidson, Rosemarie; Eccles, Diana; Cole, Trevor; Cook, Jackie; Paterson, Joan; Douglas, Fiona; Brewer, Carole; Hodgson, Shirley; Morrison, Patrick J; Walker, Lisa; Porteous, Mary E; Kennedy, M John; Pathak, Harsh; Godwin, Andrew K; Stoppa-Lyonnet, Dominique; Caux-Moncoutier, Virginie; de Pauw, Antoine; Gauthier-Villars, Marion; Mazoyer, Sylvie; Leone, Melanie; Calender, Alain; Lasset, Christine; Bonadona, Valerie; Hardouin, Agnes; Berthet, Pascaline; Bignon, Yves-Jean; Uhrhammer, Nancy; Faivre, Laurence; Loustalot, Catherine; Buys, Saundra; Daly, Mary; Miron, Alex; Terry, Mary Beth; Chung, Wendy K; John, Esther M; Southey, Melissa; Goldgar, David; Singer, Christian F; Tea, Muy-Kheng; Pfeiler, Georg; Fink-Retter, Anneliese; Hansen, Thomas v O; Ejlertsen, Bent; Johannsson, Oskar Th; Offit, Kenneth; Kirchhoff, Tomas; Gaudet, Mia M; Vijai, Joseph; Robson, Mark; Piedmonte, Marion; Phillips, Kelly-Anne; Van Le, Linda; Hoffman, James S; Ewart Toland, Amanda; Montagna, Marco; Tognazzo, Silvia; Imyanitov, Evgeny; Issacs, Claudine; Janavicius, Ramunas; Lazaro, Conxi; Blanco, Iganacio; Tornero, Eva; Navarro, Matilde; Moysich, Kirsten B; Karlan, Beth Y; Gross, Jenny; Olah, Edith; Vaszko, Tibor; Teo, Soo-Hwang; Ganz, Patricia A; Beattie, Mary S; Dorfling, Cecelia M; van Rensburg, Elizabeth J; Diez, Orland; Kwong, Ava; Schmutzler, Rita K; Wappenschmidt, Barbara; Engel, Christoph; Meindl, Alfons; Ditsch, Nina; Arnold, Norbert; Heidemann, Simone; Niederacher, Dieter; Preisler-Adams, Sabine; Gadzicki, Dorotehea; Varon-Mateeva, Raymonda; Deissler, Helmut; Gehrig, Andrea; Sutter, Christian; Kast, Karin; Fiebig, Britta; Schafer, Dieter; Caldes, Trinidad; de la Hoya, Miguel; Nevanlinna, Heli; Aittomaki, Kristiina; Plante, Marie; Spurdle, Amanda B; Neuhausen, Susan L; Ding, Yuan Chun; Wang, Xianshu; Lindor, Noralane; Fredericksen, Zachary; Pankratz, V Shane; Peterlongo, Paolo; Manoukian, Siranoush; Peissel, Bernard; Zaffaroni, Daniela; Bonanni, Bernardo; Bernard, Loris; Dolcetti, Riccardo; Papi, Laura; Ottini, Laura; Radice, Paolo; Greene, Mark H; Mai, Phuong L; Andrulis, Irene L; Glendon, Gord; Ozcelik, Hilmi; Pharoah, Paul D P; Gayther, Simon A; Simard, Jacques; Easton, Douglas F; Couch, Fergus J; Chenevix-Trench, Georgia
2012 Apr;33(4):690-702, Human mutation
— id: 232752, year: 2012, vol: 33, page: 690, stat: Journal Article,

THE MELANOMA RISK LOCI AS DETERMINANTS OF MELANOMA PROGNOSIS
Rendleman, J.; Shang, S.; Brocia, C.; Ma, M.; Shapiro, R.; Berman, R.; Pavlick, A.; Shao, Y.; Osman, I.; Kirchhoff, T.
2012 SEP;23 9 9:363-363, Annals of oncology
— id: 181682, year: 2012, vol: 23 9 9, page: 363, stat: Journal Article,

The melanoma risk loci as determinants of melanoma prognosis
Rendleman, J; Shang, S; Brocia, C; Ma, M W; Shapiro, R L; Berman, R S; Pavlick, A C; Shao, Y; Osman, I; Kirchhoff, T
2012 20 May 2012;30(15):-, Journal of clinical oncology
— id: 306092, year: 2012, vol: 30, page: , stat: Journal Article,

Y chromosome haplogroups and prostate cancer in populations of European and Ashkenazi Jewish ancestry
Wang, Zhaoming; Parikh, Hemang; Jia, Jinping; Myers, Timothy; Yeager, Meredith; Jacobs, Kevin B; Hutchinson, Amy; Burdett, Laurie; Ghosh, Arpita; Thun, Michael J; Gapstur, Susan M; Ryan Diver, W; Virtamo, Jarmo; Albanes, Demetrius; Cancel-Tassin, Geraldine; Valeri, Antoine; Cussenot, Olivier; Offit, Kenneth; Giovannucci, Ed; Ma, Jing; Stampfer, Meir J; Michael Gaziano, J; Hunter, David J; Dutra-Clarke, Ana; Kirchhoff, Tomas; Alavanja, Michael; Freeman, Laura B; Koutros, Stella; Hoover, Robert; Berndt, Sonja I; Hayes, Richard B; Agalliu, Ilir; Burk, Robert D; Wacholder, Sholom; Thomas, Gilles; Amundadottir, Laufey
2012 Jul;131(7):1173-1185, Human genetics
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Common alleles at 6q25.1 and 1p11.2 are associated with breast cancer risk for BRCA1 and BRCA2 mutation carriers
Antoniou, Antonis C; Kartsonaki, Christiana; Sinilnikova, Olga M; Soucy, Penny; McGuffog, Lesley; Healey, Sue; Lee, Andrew; Peterlongo, Paolo; Manoukian, Siranoush; Peissel, Bernard; Zaffaroni, Daniela; Cattaneo, Elisa; Barile, Monica; Pensotti, Valeria; Pasini, Barbara; Dolcetti, Riccardo; Giannini, Giuseppe; Putignano, Anna Laura; Varesco, Liliana; Radice, Paolo; Mai, Phuong L; Greene, Mark H; Andrulis, Irene L; Glendon, Gord; Ozcelik, Hilmi; Thomassen, Mads; Gerdes, Anne-Marie; Kruse, Torben A; Birk Jensen, Uffe; Cruger, Dorthe G; Caligo, Maria A; Laitman, Yael; Milgrom, Roni; Kaufman, Bella; Paluch-Shimon, Shani; Friedman, Eitan; Loman, Niklas; Harbst, Katja; Lindblom, Annika; Arver, Brita; Ehrencrona, Hans; Melin, Beatrice; Nathanson, Katherine L; Domchek, Susan M; Rebbeck, Timothy; Jakubowska, Ania; Lubinski, Jan; Gronwald, Jacek; Huzarski, Tomasz; Byrski, Tomasz; Cybulski, Cezary; Gorski, Bohdan; Osorio, Ana; Ramon y Cajal, Teresa; Fostira, Florentia; Andres, Raquel; Benitez, Javier; Hamann, Ute; Hogervorst, Frans B; Rookus, Matti A; Hooning, Maartje J; Nelen, Marcel R; van der Luijt, Rob B; van Os, Theo A M; van Asperen, Christi J; Devilee, Peter; Meijers-Heijboer, Hanne E J; Gomez Garcia, Encarna B; Peock, Susan; Cook, Margaret; Frost, Debra; Platte, Radka; Leyland, Jean; Evans, D Gareth; Lalloo, Fiona; Eeles, Ros; Izatt, Louise; Adlard, Julian; Davidson, Rosemarie; Eccles, Diana; Ong, Kai-ren; Cook, Jackie; Douglas, Fiona; Paterson, Joan; Kennedy, M John; Miedzybrodzka, Zosia; Godwin, Andrew; Stoppa-Lyonnet, Dominique; Buecher, Bruno; Belotti, Muriel; Tirapo, Carole; Mazoyer, Sylvie; Barjhoux, Laure; Lasset, Christine; Leroux, Dominique; Faivre, Laurence; Bronner, Myriam; Prieur, Fabienne; Nogues, Catherine; Rouleau, Etienne; Pujol, Pascal; Coupier, Isabelle; Frenay, Marc; Hopper, John L; Daly, Mary B; Terry, Mary B; John, Esther M; Buys, Saundra S; Yassin, Yosuf; Miron, Alexander; Goldgar, David; Singer, Christian F; Tea, Muy-Kheng; Pfeiler, Georg; Dressler, Anne Catharina; Hansen, Thomas v O; Jonson, Lars; Ejlertsen, Bent; Barkardottir, Rosa Bjork; Kirchhoff, Tomas; Offit, Kenneth; Piedmonte, Marion; Rodriguez, Gustavo; Small, Laurie; Boggess, John; Blank, Stephanie; Basil, Jack; Azodi, Masoud; Toland, Amanda Ewart; Montagna, Marco; Tognazzo, Silvia; Agata, Simona; Imyanitov, Evgeny; Janavicius, Ramunas; Lazaro, Conxi; Blanco, Ignacio; Pharoah, Paul D P; Sucheston, Lara; Karlan, Beth Y; Walsh, Christine S; Olah, Edith; Bozsik, Aniko; Teo, Soo-Hwang; Seldon, Joyce L; Beattie, Mary S; van Rensburg, Elizabeth J; Sluiter, Michelle D; Diez, Orland; Schmutzler, Rita K; Wappenschmidt, Barbara; Engel, Christoph; Meindl, Alfons; Ruehl, Ina; Varon-Mateeva, Raymonda; Kast, Karin; Deissler, Helmut; Niederacher, Dieter; Arnold, Norbert; Gadzicki, Dorothea; Schonbuchner, Ines; Caldes, Trinidad; de la Hoya, Miguel; Nevanlinna, Heli; Aittomaki, Kristiina; Dumont, Martine; Chiquette, Jocelyne; Tischkowitz, Marc; Chen, Xiaoqing; Beesley, Jonathan; Spurdle, Amanda B; Neuhausen, Susan L; Chun Ding, Yuan; Fredericksen, Zachary; Wang, Xianshu; Pankratz, Vernon S; Couch, Fergus; Simard, Jacques; Easton, Douglas F; Chenevix-Trench, Georgia
2011 Aug;20(16):3304-3321, Human molecular genetics
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Variants at 6q21 implicate PRDM1 in the etiology of therapy-induced second malignancies after Hodgkin's lymphoma
Best, Timothy; Li, Dalin; Skol, Andrew D; Kirchhoff, Tomas; Jackson, Sarah A; Yasui, Yutaka; Bhatia, Smita; Strong, Louise C; Domchek, Susan M; Nathanson, Katherine L; Olopade, Olufunmilayo I; Huang, R Stephanie; Mack, Thomas M; Conti, David V; Offit, Kenneth; Cozen, Wendy; Robison, Leslie L; Onel, Kenan
2011 Aug;17(8):941-943, Nature medicine
— id: 232762, year: 2011, vol: 17, page: 941, stat: Journal Article,

Haplotype structure in Ashkenazi Jewish BRCA1 and BRCA2 mutation carriers
Im KM; Kirchhoff T; Wang X; Green T; Chow CY; Vijai J; Korn J; Gaudet MM; Fredericksen Z; Shane Pankratz V; Guiducci C; Crenshaw A; McGuffog L; Kartsonaki C; Morrison J; Healey S; Sinilnikova OM; Mai PL; Greene MH; Piedmonte M; Rubinstein WS; Hogervorst FB; Rookus MA; Collee JM; Hoogerbrugge N; van Asperen CJ; Meijers-Heijboer HE; Van Roozendaal CE; Caldes T; Perez-Segura P; Jakubowska A; Lubinski J; Huzarski T; Blecharz P; Nevanlinna H; Aittomaki K; Lazaro C; Blanco I; Barkardottir RB; Montagna M; D'Andrea E; Devilee P; Olopade OI; Neuhausen SL; Peissel B; Bonanni B; Peterlongo P; Singer CF; Rennert G; Lejbkowicz F; Andrulis IL; Glendon G; Ozcelik H; Toland AE; Caligo MA; Beattie MS; Chan S; Domchek SM; Nathanson KL; Rebbeck TR; Phelan C; Narod S; John EM; Hopper JL; Buys SS; Daly MB; Southey MC; Terry MB; Tung N; Hansen TV; Osorio A; Benitez J; Duran M; Weitzel JN; Garber J; Hamann U; Peock S; Cook M; Oliver CT; Frost D; Platte R; Evans DG; Eeles R; Izatt L; Paterson J; Brewer C; Hodgson S; Morrison PJ; Porteous M; Walker L; Rogers MT; Side LE; Godwin AK; Schmutzler RK; Wappenschmidt B; Laitman Y; Meindl A; Deissler H; Varon-Mateeva R; Preisler-Adams S; Kast K; Venat-Bouvet L; Stoppa-Lyonnet D; Chenevix-Trench G; Easton DF; Klein RJ; Daly MJ; Friedman E; Dean M; Clark AG; Altshuler DM; Antoniou AC; Couch FJ; Offit K; Gold B
2011 Nov;130(5):685-699, Human genetics
— id: 138586, year: 2011, vol: 130, page: 685, stat: Journal Article,

Genetic variation at 9p22.2 and ovarian cancer risk for BRCA1 and BRCA2 mutation carriers
Ramus, Susan J; Kartsonaki, Christiana; Gayther, Simon A; Pharoah, Paul D P; Sinilnikova, Olga M; Beesley, Jonathan; Chen, Xiaoqing; McGuffog, Lesley; Healey, Sue; Couch, Fergus J; Wang, Xianshu; Fredericksen, Zachary; Peterlongo, Paolo; Manoukian, Siranoush; Peissel, Bernard; Zaffaroni, Daniela; Roversi, Gaia; Barile, Monica; Viel, Alessandra; Allavena, Anna; Ottini, Laura; Papi, Laura; Gismondi, Viviana; Capra, Fabio; Radice, Paolo; Greene, Mark H; Mai, Phuong L; Andrulis, Irene L; Glendon, Gord; Ozcelik, Hilmi; Thomassen, Mads; Gerdes, Anne-Marie; Kruse, Torben A; Cruger, Dorthe; Jensen, Uffe Birk; Caligo, Maria Adelaide; Olsson, Hakan; Kristoffersson, Ulf; Lindblom, Annika; Arver, Brita; Karlsson, Per; Stenmark Askmalm, Marie; Borg, Ake; Neuhausen, Susan L; Ding, Yuan Chun; Nathanson, Katherine L; Domchek, Susan M; Jakubowska, Anna; Lubinski, Jan; Huzarski, Tomasz; Byrski, Tomasz; Gronwald, Jacek; Gorski, Bohdan; Cybulski, Cezary; Debniak, Tadeusz; Osorio, Ana; Duran, Mercedes; Tejada, Maria-Isabel; Benitez, Javier; Hamann, Ute; Rookus, Matti A; Verhoef, Senno; Tilanus-Linthorst, Madeleine A; Vreeswijk, Maaike P; Bodmer, Danielle; Ausems, Margreet G E M; van Os, Theo A; Asperen, Christi J; Blok, Marinus J; Meijers-Heijboer, Hanne E J; Peock, Susan; Cook, Margaret; Oliver, Clare; Frost, Debra; Dunning, Alison M; Evans, D Gareth; Eeles, Ros; Pichert, Gabriella; Cole, Trevor; Hodgson, Shirley; Brewer, Carole; Morrison, Patrick J; Porteous, Mary; Kennedy, M John; Rogers, Mark T; Side, Lucy E; Donaldson, Alan; Gregory, Helen; Godwin, Andrew; Stoppa-Lyonnet, Dominique; Moncoutier, Virginie; Castera, Laurent; Mazoyer, Sylvie; Barjhoux, Laure; Bonadona, Valerie; Leroux, Dominique; Faivre, Laurence; Lidereau, Rosette; Nogues, Catherine; Bignon, Yves-Jean; Prieur, Fabienne; Collonge-Rame, Marie-Agnes; Venat-Bouvet, Laurence; Fert-Ferrer, Sandra; Miron, Alex; Buys, Saundra S; Hopper, John L; Daly, Mary B; John, Esther M; Terry, Mary Beth; Goldgar, David; Hansen, Thomas v O; Jonson, Lars; Ejlertsen, Bent; Agnarsson, Bjarni A; Offit, Kenneth; Kirchhoff, Tomas; Vijai, Joseph; Dutra-Clarke, Ana V C; Przybylo, Jennifer A; Montagna, Marco; Casella, Cinzia; Imyanitov, Evgeny N; Janavicius, Ramunas; Blanco, Ignacio; Lazaro, Conxi; Moysich, Kirsten B; Karlan, Beth Y; Gross, Jenny; Beattie, Mary S; Schmutzler, Rita; Wappenschmidt, Barbara; Meindl, Alfons; Ruehl, Ina; Fiebig, Britta; Sutter, Christian; Arnold, Norbert; Deissler, Helmut; Varon-Mateeva, Raymonda; Kast, Karin; Niederacher, Dieter; Gadzicki, Dorothea; Caldes, Trinidad; de la Hoya, Miguel; Nevanlinna, Heli; Aittomaki, Kristiina; Simard, Jacques; Soucy, Penny; Spurdle, Amanda B; Holland, Helene; Chenevix-Trench, Georgia; Easton, Douglas F; Antoniou, Antonis C
2011 Jan 19;103(2):105-116, Journal of the National Cancer Institute
— id: 128879, year: 2011, vol: 103, page: 105, stat: Journal Article,

Common breast cancer susceptibility alleles and the risk of breast cancer for BRCA1 and BRCA2 mutation carriers: implications for risk prediction
Antoniou, Antonis C; Beesley, Jonathan; McGuffog, Lesley; Sinilnikova, Olga M; Healey, Sue; Neuhausen, Susan L; Ding, Yuan Chun; Rebbeck, Timothy R; Weitzel, Jeffrey N; Lynch, Henry T; Isaacs, Claudine; Ganz, Patricia A; Tomlinson, Gail; Olopade, Olufunmilayo I; Couch, Fergus J; Wang, Xianshu; Lindor, Noralane M; Pankratz, Vernon S; Radice, Paolo; Manoukian, Siranoush; Peissel, Bernard; Zaffaroni, Daniela; Barile, Monica; Viel, Alessandra; Allavena, Anna; Dall'Olio, Valentina; Peterlongo, Paolo; Szabo, Csilla I; Zikan, Michal; Claes, Kathleen; Poppe, Bruce; Foretova, Lenka; Mai, Phuong L; Greene, Mark H; Rennert, Gad; Lejbkowicz, Flavio; Glendon, Gord; Ozcelik, Hilmi; Andrulis, Irene L; Thomassen, Mads; Gerdes, Anne-Marie; Sunde, Lone; Cruger, Dorthe; Birk Jensen, Uffe; Caligo, Maria; Friedman, Eitan; Kaufman, Bella; Laitman, Yael; Milgrom, Roni; Dubrovsky, Maya; Cohen, Shimrit; Borg, Ake; Jernstrom, Helena; Lindblom, Annika; Rantala, Johanna; Stenmark-Askmalm, Marie; Melin, Beatrice; Nathanson, Kate; Domchek, Susan; Jakubowska, Ania; Lubinski, Jan; Huzarski, Tomasz; Osorio, Ana; Lasa, Adriana; Duran, Mercedes; Tejada, Maria-Isabel; Godino, Javier; Benitez, Javier; Hamann, Ute; Kriege, Mieke; Hoogerbrugge, Nicoline; van der Luijt, Rob B; van Asperen, Christi J; Devilee, Peter; Meijers-Heijboer, E J; Blok, Marinus J; Aalfs, Cora M; Hogervorst, Frans; Rookus, Matti; Cook, Margaret; Oliver, Clare; Frost, Debra; Conroy, Don; Evans, D Gareth; Lalloo, Fiona; Pichert, Gabriella; Davidson, Rosemarie; Cole, Trevor; Cook, Jackie; Paterson, Joan; Hodgson, Shirley; Morrison, Patrick J; Porteous, Mary E; Walker, Lisa; Kennedy, M John; Dorkins, Huw; Peock, Susan; Godwin, Andrew K; Stoppa-Lyonnet, Dominique; de Pauw, Antoine; Mazoyer, Sylvie; Bonadona, Valerie; Lasset, Christine; Dreyfus, Helene; Leroux, Dominique; Hardouin, Agnes; Berthet, Pascaline; Faivre, Laurence; Loustalot, Catherine; Noguchi, Tetsuro; Sobol, Hagay; Rouleau, Etienne; Nogues, Catherine; Frenay, Marc; Venat-Bouvet, Laurence; Hopper, John L; Daly, Mary B; Terry, Mary B; John, Esther M; Buys, Saundra S; Yassin, Yosuf; Miron, Alexander; Goldgar, David; Singer, Christian F; Dressler, Anne Catharina; Gschwantler-Kaulich, Daphne; Pfeiler, Georg; Hansen, Thomas V O; Jonson, Lars; Agnarsson, Bjarni A; Kirchhoff, Tomas; Offit, Kenneth; Devlin, Vincent; Dutra-Clarke, Ana; Piedmonte, Marion; Rodriguez, Gustavo C; Wakeley, Katie; Boggess, John F; Basil, Jack; Schwartz, Peter E; Blank, Stephanie V; Toland, Amanda Ewart; Montagna, Marco; Casella, Cinzia; Imyanitov, Evgeny; Tihomirova, Laima; Blanco, Ignacio; Lazaro, Conxi; Ramus, Susan J; Sucheston, Lara; Karlan, Beth Y; Gross, Jenny; Schmutzler, Rita; Wappenschmidt, Barbara; Engel, Christoph; Meindl, Alfons; Lochmann, Magdalena; Arnold, Norbert; Heidemann, Simone; Varon-Mateeva, Raymonda; Niederacher, Dieter; Sutter, Christian; Deissler, Helmut; Gadzicki, Dorothea; Preisler-Adams, Sabine; Kast, Karin; Schonbuchner, Ines; Caldes, Trinidad; de la Hoya, Miguel; Aittomaki, Kristiina; Nevanlinna, Heli; Simard, Jacques; Spurdle, Amanda B; Holland, Helene; Chen, Xiaoqing; Platte, Radka; Chenevix-Trench, Georgia; Easton, Douglas F
2010 Dec 1;70(23):9742-9754, Cancer research
— id: 128880, year: 2010, vol: 70, page: 9742, stat: Journal Article,

A locus on 19p13 modifies risk of breast cancer in BRCA1 mutation carriers and is associated with hormone receptor-negative breast cancer in the general population
Antoniou, Antonis C; Wang, Xianshu; Fredericksen, Zachary S; McGuffog, Lesley; Tarrell, Robert; Sinilnikova, Olga M; Healey, Sue; Morrison, Jonathan; Kartsonaki, Christiana; Lesnick, Timothy; Ghoussaini, Maya; Barrowdale, Daniel; Peock, Susan; Cook, Margaret; Oliver, Clare; Frost, Debra; Eccles, Diana; Evans, D Gareth; Eeles, Ros; Izatt, Louise; Chu, Carol; Douglas, Fiona; Paterson, Joan; Stoppa-Lyonnet, Dominique; Houdayer, Claude; Mazoyer, Sylvie; Giraud, Sophie; Lasset, Christine; Remenieras, Audrey; Caron, Olivier; Hardouin, Agnes; Berthet, Pascaline; Hogervorst, Frans B L; Rookus, Matti A; Jager, Agnes; van den Ouweland, Ans; Hoogerbrugge, Nicoline; van der Luijt, Rob B; Meijers-Heijboer, Hanne; Gomez Garcia, Encarna B; Devilee, Peter; Vreeswijk, Maaike P G; Lubinski, Jan; Jakubowska, Anna; Gronwald, Jacek; Huzarski, Tomasz; Byrski, Tomasz; Gorski, Bohdan; Cybulski, Cezary; Spurdle, Amanda B; Holland, Helene; Goldgar, David E; John, Esther M; Hopper, John L; Southey, Melissa; Buys, Saundra S; Daly, Mary B; Terry, Mary-Beth; Schmutzler, Rita K; Wappenschmidt, Barbara; Engel, Christoph; Meindl, Alfons; Preisler-Adams, Sabine; Arnold, Norbert; Niederacher, Dieter; Sutter, Christian; Domchek, Susan M; Nathanson, Katherine L; Rebbeck, Timothy; Blum, Joanne L; Piedmonte, Marion; Rodriguez, Gustavo C; Wakeley, Katie; Boggess, John F; Basil, Jack; Blank, Stephanie V; Friedman, Eitan; Kaufman, Bella; Laitman, Yael; Milgrom, Roni; Andrulis, Irene L; Glendon, Gord; Ozcelik, Hilmi; Kirchhoff, Tomas; Vijai, Joseph; Gaudet, Mia M; Altshuler, David; Guiducci, Candace; Loman, Niklas; Harbst, Katja; Rantala, Johanna; Ehrencrona, Hans; Gerdes, Anne-Marie; Thomassen, Mads; Sunde, Lone; Peterlongo, Paolo; Manoukian, Siranoush; Bonanni, Bernardo; Viel, Alessandra; Radice, Paolo; Caldes, Trinidad; de la Hoya, Miguel; Singer, Christian F; Fink-Retter, Anneliese; Greene, Mark H; Mai, Phuong L; Loud, Jennifer T; Guidugli, Lucia; Lindor, Noralane M; Hansen, Thomas V O; Nielsen, Finn C; Blanco, Ignacio; Lazaro, Conxi; Garber, Judy; Ramus, Susan J; Gayther, Simon A; Phelan, Catherine; Narod, Stephen; Szabo, Csilla I; Benitez, Javier; Osorio, Ana; Nevanlinna, Heli; Heikkinen, Tuomas; Caligo, Maria A; Beattie, Mary S; Hamann, Ute; Godwin, Andrew K; Montagna, Marco; Casella, Cinzia; Neuhausen, Susan L; Karlan, Beth Y; Tung, Nadine; Toland, Amanda E; Weitzel, Jeffrey; Olopade, Olofunmilayo; Simard, Jacques; Soucy, Penny; Rubinstein, Wendy S; Arason, Adalgeir; Rennert, Gad; Martin, Nicholas G; Montgomery, Grant W; Chang-Claude, Jenny; Flesch-Janys, Dieter; Brauch, Hiltrud; Severi, Gianluca; Baglietto, Laura; Cox, Angela; Cross, Simon S; Miron, Penelope; Gerty, Sue M; Tapper, William; Yannoukakos, Drakoulis; Fountzilas, George; Fasching, Peter A; Beckmann, Matthias W; Dos Santos Silva, Isabel; Peto, Julian; Lambrechts, Diether; Paridaens, Robert; Rudiger, Thomas; Forsti, Asta; Winqvist, Robert; Pylkas, Katri; Diasio, Robert B; Lee, Adam M; Eckel-Passow, Jeanette; Vachon, Celine; Blows, Fiona; Driver, Kristy; Dunning, Alison; Pharoah, Paul P D; Offit, Kenneth; Pankratz, V Shane; Hakonarson, Hakon; Chenevix-Trench, Georgia; Easton, Douglas F; Couch, Fergus J
2010 Oct;42(10):885-892, Nature genetics
— id: 128883, year: 2010, vol: 42, page: 885, stat: Journal Article,

Germline BRCA mutations denote a clinicopathologic subset of prostate cancer
Gallagher, David J; Gaudet, Mia M; Pal, Prodipto; Kirchhoff, Tomas; Balistreri, Lisa; Vora, Kinjal; Bhatia, Jasmine; Stadler, Zsofia; Fine, Samson W; Reuter, Victor; Zelefsky, Michael; Morris, Michael J; Scher, Howard I; Klein, Robert J; Norton, Larry; Eastham, James A; Scardino, Peter T; Robson, Mark E; Offit, Kenneth
2010 Apr 1;16(7):2115-2121, Clinical cancer research
— id: 128885, year: 2010, vol: 16, page: 2115, stat: Journal Article,

Susceptibility loci associated with prostate cancer progression and mortality
Gallagher, David J; Vijai, Joseph; Cronin, Angel M; Bhatia, Jasmine; Vickers, Andrew J; Gaudet, Mia M; Fine, Samson; Reuter, Victor; Scher, Howard I; Hallden, Christer; Dutra-Clarke, Ana; Klein, Robert J; Scardino, Peter T; Eastham, James A; Lilja, Hans; Kirchhoff, Tomas; Offit, Kenneth
2010 May 15;16(10):2819-2832, Clinical cancer research
— id: 128884, year: 2010, vol: 16, page: 2819, stat: Journal Article,

Common genetic variants and modification of penetrance of BRCA2-associated breast cancer
Gaudet, Mia M; Kirchhoff, Tomas; Green, Todd; Vijai, Joseph; Korn, Joshua M; Guiducci, Candace; Segre, Ayellet V; McGee, Kate; McGuffog, Lesley; Kartsonaki, Christiana; Morrison, Jonathan; Healey, Sue; Sinilnikova, Olga M; Stoppa-Lyonnet, Dominique; Mazoyer, Sylvie; Gauthier-Villars, Marion; Sobol, Hagay; Longy, Michel; Frenay, Marc; Hogervorst, Frans B L; Rookus, Matti A; Collee, J Margriet; Hoogerbrugge, Nicoline; van Roozendaal, Kees E P; Piedmonte, Marion; Rubinstein, Wendy; Nerenstone, Stacy; Van Le, Linda; Blank, Stephanie V; Caldes, Trinidad; de la Hoya, Miguel; Nevanlinna, Heli; Aittomaki, Kristiina; Lazaro, Conxi; Blanco, Ignacio; Arason, Adalgeir; Johannsson, Oskar T; Barkardottir, Rosa B; Devilee, Peter; Olopade, Olofunmilayo I; Neuhausen, Susan L; Wang, Xianshu; Fredericksen, Zachary S; Peterlongo, Paolo; Manoukian, Siranoush; Barile, Monica; Viel, Alessandra; Radice, Paolo; Phelan, Catherine M; Narod, Steven; Rennert, Gad; Lejbkowicz, Flavio; Flugelman, Anath; Andrulis, Irene L; Glendon, Gord; Ozcelik, Hilmi; Toland, Amanda E; Montagna, Marco; D'Andrea, Emma; Friedman, Eitan; Laitman, Yael; Borg, Ake; Beattie, Mary; Ramus, Susan J; Domchek, Susan M; Nathanson, Katherine L; Rebbeck, Tim; Spurdle, Amanda B; Chen, Xiaoqing; Holland, Helene; John, Esther M; Hopper, John L; Buys, Saundra S; Daly, Mary B; Southey, Melissa C; Terry, Mary Beth; Tung, Nadine; Overeem Hansen, Thomas V; Nielsen, Finn C; Greene, Mark H; Mai, Phuong L; Osorio, Ana; Duran, Mercedes; Andres, Raquel; Benitez, Javier; Weitzel, Jeffrey N; Garber, Judy; Hamann, Ute; Peock, Susan; Cook, Margaret; Oliver, Clare; Frost, Debra; Platte, Radka; Evans, D Gareth; Lalloo, Fiona; Eeles, Ros; Izatt, Louise; Walker, Lisa; Eason, Jacqueline; Barwell, Julian; Godwin, Andrew K; Schmutzler, Rita K; Wappenschmidt, Barbara; Engert, Stefanie; Arnold, Norbert; Gadzicki, Dorothea; Dean, Michael; Gold, Bert; Klein, Robert J; Couch, Fergus J; Chenevix-Trench, Georgia; Easton, Douglas F; Daly, Mark J; Antoniou, Antonis C; Altshuler, David M; Offit, Kenneth; Sinilnikova, Olga M; Stoppa-Lyonnet, Dominique; Mazoyer, Sylvie; Gauthier-Villars, Marion; Sobol, Hagay; Longy, Michel; Frenay, Marc; Sinilnikova, Olga; Barjhoux, Laure; Giraud, Sophie; Leone, Melanie; Mazoyer, Sylvie; Stoppa-Lyonnet, Dominique; Gauthier-Villars, Marion; Houdayer, Claude; Moncoutier, Virginie; Belotti, Muriel; de Pauw, Antoine; Bressac-de-Paillerets, Brigitte; Remenieras, Audrey; Byrde, Veronique; Caron, Olivier; Lenoir, Gilbert; Bignon, Yves-Jean; Uhrhammer, Nancy; Lasset, Christine; Bonadona, Valerie; Hardouin, Agnes; Berthet, Pascaline; Sobol, Hagay; Bourdon, Violaine; Noguchi, Tetsuro; Eisinger, Francois; Coulet, Florence; Colas, Chrystelle; Soubrier, Florent; Coupier, Isabelle; Peyrat, Jean-Philippe; Fournier, Joelle; Revillion, Francoise; Vennin, Philippe; Adenis, Claude; Rouleau, Etienne; Lidereau, Rosette; Demange, Liliane; Nogues, Catherine; Muller, Daniele; Fricker, Jean-Pierre; Longy, Michel; Sevenet, Nicolas; Toulas, Christine; Guimbaud, Rosine; Gladieff, Laurence; Feillel, Viviane; Leroux, Dominique; Dreyfus, Helene; Rebischung, Christine; Cassini, Cecile; Faivre, Laurence; Prieur, Fabienne; Ferrer, Sandra Fert; Frenay, Marc; Venat-Bouvet, Laurence; Lynch, Henry T; Hogervorst, Frans B L; Rookus, Matti A; Collee, J Margriet; Hoogerbrugge, Nicoline; van Roozendaal, Kees E P; Hogervorst, Frans B L; Verhoef, Senno; Verheus, Martijn; van 't Veer, Laura J; van Leeuwen, Flora E; Rookus, Matti A; Collee, Margriet; van den Ouweland, Ans M W; Jager, Agnes; Hooning, Maartje J; Tilanus-Linthorst, Madeleine M A; Seynaeve, Caroline; van Asperen, Christi J; Wijnen, Juul T; Vreeswijk, Maaike P; Tollenaar, Rob A; Devilee, Peter; Ligtenberg, Marjolijn J; Hoogerbrugge, Nicoline; Ausems, Margreet G; van der Luijt, Rob B; Aalfs, Cora M; van Os, Theo A; Gille, Johan J P; Waisfisz, Quinten; Meijers-Heijboer, Hanne; Gomez-Garcia, Encarna B; van Roozendaal, Cees E; Blok, Marinus J; Oosterwijk, Jan C; van der Hout, Annemarie H; Mourits, Marian J; Vasen, Hans F; Spurdle, Amanda B; Chenevix-Trench, Georgia
2010 Oct;6(10):e1001183-e1001183, PLoS genetics
— id: 128881, year: 2010, vol: 6, page: e1001183, stat: Journal Article,

Genome-wide association studies of cancer predisposition
Stadler, Zsofia K; Vijai, Joseph; Thom, Peter; Kirchhoff, Tomas; Hansen, Nichole A L; Kauff, Noah D; Robson, Mark; Offit, Kenneth
2010 Oct;24(5):973-996, Hematology-oncology clinics of North America
— id: 128882, year: 2010, vol: 24, page: 973, stat: Journal Article,

Common variants in LSP1, 2q35 and 8q24 and breast cancer risk for BRCA1 and BRCA2 mutation carriers
Antoniou, Antonis C; Sinilnikova, Olga M; McGuffog, Lesley; Healey, Sue; Nevanlinna, Heli; Heikkinen, Tuomas; Simard, Jacques; Spurdle, Amanda B; Beesley, Jonathan; Chen, Xiaoqing; Neuhausen, Susan L; Ding, Yuan C; Couch, Fergus J; Wang, Xianshu; Fredericksen, Zachary; Peterlongo, Paolo; Peissel, Bernard; Bonanni, Bernardo; Viel, Alessandra; Bernard, Loris; Radice, Paolo; Szabo, Csilla I; Foretova, Lenka; Zikan, Michal; Claes, Kathleen; Greene, Mark H; Mai, Phuong L; Rennert, Gad; Lejbkowicz, Flavio; Andrulis, Irene L; Ozcelik, Hilmi; Glendon, Gord; Gerdes, Anne-Marie; Thomassen, Mads; Sunde, Lone; Caligo, Maria A; Laitman, Yael; Kontorovich, Tair; Cohen, Shimrit; Kaufman, Bella; Dagan, Efrat; Baruch, Ruth Gershoni; Friedman, Eitan; Harbst, Katja; Barbany-Bustinza, Gisela; Rantala, Johanna; Ehrencrona, Hans; Karlsson, Per; Domchek, Susan M; Nathanson, Katherine L; Osorio, Ana; Blanco, Ignacio; Lasa, Adriana; Benitez, Javier; Hamann, Ute; Hogervorst, Frans B L; Rookus, Matti A; Collee, J Margriet; Devilee, Peter; Ligtenberg, Marjolijn J; van der Luijt, Rob B; Aalfs, Cora M; Waisfisz, Quinten; Wijnen, Juul; van Roozendaal, Cornelis E P; Peock, Susan; Cook, Margaret; Frost, Debra; Oliver, Clare; Platte, Radka; Evans, D Gareth; Lalloo, Fiona; Eeles, Rosalind; Izatt, Louise; Davidson, Rosemarie; Chu, Carol; Eccles, Diana; Cole, Trevor; Hodgson, Shirley; Godwin, Andrew K; Stoppa-Lyonnet, Dominique; Buecher, Bruno; Leone, Melanie; Bressac-de Paillerets, Brigitte; Remenieras, Audrey; Caron, Olivier; Lenoir, Gilbert M; Sevenet, Nicolas; Longy, Michel; Ferrer, Sandra Fert; Prieur, Fabienne; Goldgar, David; Miron, Alexander; John, Esther M; Buys, Saundra S; Daly, Mary B; Hopper, John L; Terry, Mary Beth; Yassin, Yosuf; Singer, Christian; Gschwantler-Kaulich, Daphne; Staudigl, Christine; Hansen, Thomas v O; Barkardottir, Rosa Bjork; Kirchhoff, Tomas; Pal, Prodipto; Kosarin, Kristi; Offit, Kenneth; Piedmonte, Marion; Rodriguez, Gustavo C; Wakeley, Katie; Boggess, John F; Basil, Jack; Schwartz, Peter E; Blank, Stephanie V; Toland, Amanda E; Montagna, Marco; Casella, Cinzia; Imyanitov, Evgeny N; Allavena, Anna; Schmutzler, Rita K; Versmold, Beatrix; Engel, Christoph; Meindl, Alfons; Ditsch, Nina; Arnold, Norbert; Niederacher, Dieter; Deissler, Helmut; Fiebig, Britta; Suttner, Christian; Schonbuchner, Ines; Gadzicki, Dorothea; Caldes, Trinidad; de la Hoya, Miguel; Pooley, Karen A; Easton, Douglas F; Chenevix-Trench, Georgia
2009 Nov 15;18(22):4442-4456, Human molecular genetics
— id: 128886, year: 2009, vol: 18, page: 4442, stat: Journal Article,

Altered tumor formation and evolutionary selection of genetic variants in the human MDM4 oncogene
Atwal, Gurinder Singh; Kirchhoff, Tomas; Bond, Elisabeth E; Montagna, Marco; Menin, Chiara; Bertorelle, Roberta; Scaini, Maria Chiara; Bartel, Frank; Bohnke, Anja; Pempe, Christina; Gradhand, Elise; Hauptmann, Steffen; Offit, Kenneth; Levine, Arnold J; Bond, Gareth L
2009 Jun 23;106(25):10236-10241, Proceedings of the National Academy of Sciences of the United States of America
— id: 128891, year: 2009, vol: 106, page: 10236, stat: Journal Article,

The 6q22.33 locus and breast cancer susceptibility
Kirchhoff, Tomas; Chen, Zhang-qun; Gold, Bert; Pal, Prodipto; Gaudet, Mia M; Kosarin, Kristi; Levine, Douglas A; Gregersen, Peter; Spencer, Sara; Harlan, Megan; Robson, Mark; Klein, Robert J; Hudis, Clifford A; Norton, Larry; Dean, Michael; Offit, Kenneth
2009 Sep;18(9):2468-2475, Cancer epidemiology biomarkers & prevention
— id: 128889, year: 2009, vol: 18, page: 2468, stat: Journal Article,

Functional redundancy of exon 12 of BRCA2 revealed by a comprehensive analysis of the c.6853A>G (p.I2285V) variant
Li, Lili; Biswas, Kajal; Habib, Laura Anne; Kuznetsov, Sergey G; Hamel, Nancy; Kirchhoff, Tomas; Wong, Nora; Armel, Susan; Chong, George; Narod, Steven A; Claes, Kathleen; Offit, Kenneth; Robson, Mark E; Stauffer, Stacey; Sharan, Shyam K; Foulkes, William D
2009 Nov;30(11):1543-1550, Human mutation
— id: 128887, year: 2009, vol: 30, page: 1543, stat: Journal Article,

Evaluation of a candidate breast cancer associated SNP in ERCC4 as a risk modifier in BRCA1 and BRCA2 mutation carriers. Results from the Consortium of Investigators of Modifiers of BRCA1/BRCA2 (CIMBA)
Osorio, A; Milne, R L; Pita, G; Peterlongo, P; Heikkinen, T; Simard, J; Chenevix-Trench, G; Spurdle, A B; Beesley, J; Chen, X; Healey, S; Neuhausen, S L; Ding, Y C; Couch, F J; Wang, X; Lindor, N; Manoukian, S; Barile, M; Viel, A; Tizzoni, L; Szabo, C I; Foretova, L; Zikan, M; Claes, K; Greene, M H; Mai, P; Rennert, G; Lejbkowicz, F; Barnett-Griness, O; Andrulis, I L; Ozcelik, H; Weerasooriya, N; Gerdes, A-M; Thomassen, M; Cruger, D G; Caligo, M A; Friedman, E; Kaufman, B; Laitman, Y; Cohen, S; Kontorovich, T; Gershoni-Baruch, R; Dagan, E; Jernstrom, H; Askmalm, M S; Arver, B; Malmer, B; Domchek, S M; Nathanson, K L; Brunet, J; Ramon Y Cajal, T; Yannoukakos, D; Hamann, U; Hogervorst, F B L; Verhoef, S; Gomez Garcia, E B; Wijnen, J T; van den Ouweland, A; Easton, D F; Peock, S; Cook, M; Oliver, C T; Frost, D; Luccarini, C; Evans, D G; Lalloo, F; Eeles, R; Pichert, G; Cook, J; Hodgson, S; Morrison, P J; Douglas, F; Godwin, A K; Sinilnikova, O M; Barjhoux, L; Stoppa-Lyonnet, D; Moncoutier, V; Giraud, S; Cassini, C; Olivier-Faivre, L; Revillion, F; Peyrat, J-P; Muller, D; Fricker, J-P; Lynch, H T; John, E M; Buys, S; Daly, M; Hopper, J L; Terry, M B; Miron, A; Yassin, Y; Goldgar, D; Singer, C F; Gschwantler-Kaulich, D; Pfeiler, G; Spiess, A-C; Hansen, Thomas V O; Johannsson, O T; Kirchhoff, T; Offit, K; Kosarin, K; Piedmonte, M; Rodriguez, G C; Wakeley, K; Boggess, J F; Basil, J; Schwartz, P E; Blank, S V; Toland, A E; Montagna, M; Casella, C; Imyanitov, E N; Allavena, A; Schmutzler, R K; Versmold, B; Engel, C; Meindl, A; Ditsch, N; Arnold, N; Niederacher, D; Deissler, H; Fiebig, B; Varon-Mateeva, R; Schaefer, D; Froster, U G; Caldes, T; de la Hoya, M; McGuffog, L; Antoniou, A C; Nevanlinna, H; Radice, P; Benitez, J
2009 Dec 15;101(12):2048-2054, British journal of cancer
— id: 106601, year: 2009, vol: 101, page: 2048, stat: Journal Article,

Mutations in a gene encoding a midbody kelch protein in familial and sporadic classical Hodgkin lymphoma lead to binucleated cells
Salipante, Stephen J; Mealiffe, Matthew E; Wechsler, Jeremy; Krem, Maxwell M; Liu, Yajuan; Namkoong, Shinae; Bhagat, Govind; Kirchhoff, Tomas; Offit, Kenneth; Lynch, Henry; Wiernik, Peter H; Roshal, Mikhail; McMaster, Mary Lou; Tucker, Margaret; Fromm, Jonathan R; Goldin, Lynn R; Horwitz, Marshall S
2009 Sep 1;106(35):14920-14925, Proceedings of the National Academy of Sciences of the United States of America
— id: 128890, year: 2009, vol: 106, page: 14920, stat: Journal Article,

Characterization of a natural mutator variant of human DNA polymerase lambda which promotes chromosomal instability by compromising NHEJ
Terrados, Gloria; Capp, Jean-Pascal; Canitrot, Yvan; Garcia-Diaz, Miguel; Bebenek, Katarzyna; Kirchhoff, Tomas; Villanueva, Alberto; Boudsocq, Francois; Bergoglio, Valerie; Cazaux, Christophe; Kunkel, Thomas A; Hoffmann, Jean-Sebastien; Blanco, Luis
2009 ;4(10):e7290-e7290, PLoS one
— id: 128888, year: 2009, vol: 4, page: e7290, stat: Journal Article,

A rapid and reliable test for BRCA1 and BRCA2 founder mutation analysis in paraffin tissue using pyrosequencing
Zhang, Liying; Kirchhoff, Tomas; Yee, Cindy J; Offit, Kenneth
2009 May;11(3):176-181, Journal of molecular diagnostics
— id: 128892, year: 2009, vol: 11, page: 176, stat: Journal Article,

The signatures of autozygosity among patients with colorectal cancer
Bacolod, Manny D; Schemmann, Gunter S; Wang, Shuang; Shattock, Richard; Giardina, Sarah F; Zeng, Zhaoshi; Shia, Jinru; Stengel, Robert F; Gerry, Norman; Hoh, Josephine; Kirchhoff, Tomas; Gold, Bert; Christman, Michael F; Offit, Kenneth; Gerald, William L; Notterman, Daniel A; Ott, Jurg; Paty, Philip B; Barany, Francis
2008 Apr 15;68(8):2610-2621, Cancer research
— id: 128894, year: 2008, vol: 68, page: 2610, stat: Journal Article,

Genome-wide association study provides evidence for a breast cancer risk locus at 6q22.33
Gold, Bert; Kirchhoff, Tomas; Stefanov, Stefan; Lautenberger, James; Viale, Agnes; Garber, Judy; Friedman, Eitan; Narod, Steven; Olshen, Adam B; Gregersen, Peter; Kosarin, Kristi; Olsh, Adam; Bergeron, Julie; Ellis, Nathan A; Klein, Robert J; Clark, Andrew G; Norton, Larry; Dean, Michael; Boyd, Jeff; Offit, Kenneth
2008 Mar 18;105(11):4340-4345, Proceedings of the National Academy of Sciences of the United States of America
— id: 128895, year: 2008, vol: 105, page: 4340, stat: Journal Article,

Analysis of genetic variation in Ashkenazi Jews by high density SNP genotyping
Olshen, Adam B; Gold, Bert; Lohmueller, Kirk E; Struewing, Jeffery P; Satagopan, Jaya; Stefanov, Stefan A; Eskin, Eleazar; Kirchhoff, Tomas; Lautenberger, James A; Klein, Robert J; Friedman, Eitan; Norton, Larry; Ellis, Nathan A; Viale, Agnes; Lee, Catherine S; Borgen, Patrick I; Clark, Andrew G; Offit, Kenneth; Boyd, Jeff
2008 ;9:14-14, BMC genetics
— id: 128896, year: 2008, vol: 9, page: 14, stat: Journal Article,

Identification and characterization of novel SNPs in CHEK2 in Ashkenazi Jewish men with prostate cancer
Tischkowitz, Marc D; Yilmaz, Ahmet; Chen, Long Q; Karyadi, Danielle M; Novak, David; Kirchhoff, Tomas; Hamel, Nancy; Tavtigian, Sean V; Kolb, Suzanne; Bismar, Tarek A; Aloyz, Raquel; Nelson, Peter S; Hood, Lee; Narod, Steven A; White, Kirsten A; Ostrander, Elaine A; Isaacs, William B; Offit, Kenneth; Cooney, Kathleen A; Stanford, Janet L; Foulkes, William D
2008 Oct 18;270(1):173-180, Cancer letters
— id: 128893, year: 2008, vol: 270, page: 173, stat: Journal Article,

RAD51 135G-->C modifies breast cancer risk among BRCA2 mutation carriers: results from a combined analysis of 19 studies
Antoniou, Antonis C; Sinilnikova, Olga M; Simard, Jacques; Leone, Melanie; Dumont, Martine; Neuhausen, Susan L; Struewing, Jeffery P; Stoppa-Lyonnet, Dominique; Barjhoux, Laure; Hughes, David J; Coupier, Isabelle; Belotti, Muriel; Lasset, Christine; Bonadona, Valerie; Bignon, Yves-Jean; Rebbeck, Timothy R; Wagner, Theresa; Lynch, Henry T; Domchek, Susan M; Nathanson, Katherine L; Garber, Judy E; Weitzel, Jeffrey; Narod, Steven A; Tomlinson, Gail; Olopade, Olufunmilayo I; Godwin, Andrew; Isaacs, Claudine; Jakubowska, Anna; Lubinski, Jan; Gronwald, Jacek; Gorski, Bohdan; Byrski, Tomasz; Huzarski, Tomasz; Peock, Susan; Cook, Margaret; Baynes, Caroline; Murray, Alexandra; Rogers, Mark; Daly, Peter A; Dorkins, Huw; Schmutzler, Rita K; Versmold, Beatrix; Engel, Christoph; Meindl, Alfons; Arnold, Norbert; Niederacher, Dieter; Deissler, Helmut; Spurdle, Amanda B; Chen, Xiaoqing; Waddell, Nicola; Cloonan, Nicole; Kirchhoff, Tomas; Offit, Kenneth; Friedman, Eitan; Kaufmann, Bella; Laitman, Yael; Galore, Gilli; Rennert, Gad; Lejbkowicz, Flavio; Raskin, Leon; Andrulis, Irene L; Ilyushik, Eduard; Ozcelik, Hilmi; Devilee, Peter; Vreeswijk, Maaike P G; Greene, Mark H; Prindiville, Sheila A; Osorio, Ana; Benitez, Javier; Zikan, Michal; Szabo, Csilla I; Kilpivaara, Outi; Nevanlinna, Heli; Hamann, Ute; Durocher, Francine; Arason, Adalgeir; Couch, Fergus J; Easton, Douglas F; Chenevix-Trench, Georgia
2007 Dec;81(6):1186-1200, American journal of human genetics
— id: 128897, year: 2007, vol: 81, page: 1186, stat: Journal Article,

AURKA F31I polymorphism and breast cancer risk in BRCA1 and BRCA2 mutation carriers: a consortium of investigators of modifiers of BRCA1/2 study
Couch, Fergus J; Sinilnikova, Olga; Vierkant, Robert A; Pankratz, V Shane; Fredericksen, Zachary S; Stoppa-Lyonnet, Dominique; Coupier, Isabelle; Hughes, David; Hardouin, Agnes; Berthet, Pascaline; Peock, Susan; Cook, Margaret; Baynes, Caroline; Hodgson, Shirley; Morrison, Patrick J; Porteous, Mary E; Jakubowska, Anna; Lubinski, Jan; Gronwald, Jacek; Spurdle, Amanda B; Schmutzler, Rita; Versmold, Beatrix; Engel, Christoph; Meindl, Alfons; Sutter, Christian; Horst, Jurgen; Schaefer, Dieter; Offit, Kenneth; Kirchhoff, Tomas; Andrulis, Irene L; Ilyushik, Eduard; Glendon, Gordon; Devilee, Peter; Vreeswijk, Maaike P G; Vasen, Hans F A; Borg, Ake; Backenhorn, Katja; Struewing, Jeffery P; Greene, Mark H; Neuhausen, Susan L; Rebbeck, Timothy R; Nathanson, Katherine; Domchek, Susan; Wagner, Theresa; Garber, Judy E; Szabo, Csilla; Zikan, Michal; Foretova, Lenka; Olson, Janet E; Sellers, Thomas A; Lindor, Noralane; Nevanlinna, Heli; Tommiska, Johanna; Aittomaki, Kristiina; Hamann, Ute; Rashid, Muhammad U; Torres, Diana; Simard, Jacques; Durocher, Francine; Guenard, Frederic; Lynch, Henry T; Isaacs, Claudine; Weitzel, Jeffrey; Olopade, Olufunmilayo I; Narod, Steven; Daly, Mary B; Godwin, Andrew K; Tomlinson, Gail; Easton, Douglas F; Chenevix-Trench, Georgia; Antoniou, Antonis C
2007 Jul;16(7):1416-1421, Cancer epidemiology biomarkers & prevention
— id: 128899, year: 2007, vol: 16, page: 1416, stat: Journal Article,

Network modeling links breast cancer susceptibility and centrosome dysfunction
Pujana, Miguel Angel; Han, Jing-Dong J; Starita, Lea M; Stevens, Kristen N; Tewari, Muneesh; Ahn, Jin Sook; Rennert, Gad; Moreno, Victor; Kirchhoff, Tomas; Gold, Bert; Assmann, Volker; Elshamy, Wael M; Rual, Jean-Francois; Levine, Douglas; Rozek, Laura S; Gelman, Rebecca S; Gunsalus, Kristin C; Greenberg, Roger A; Sobhian, Bijan; Bertin, Nicolas; Venkatesan, Kavitha; Ayivi-Guedehoussou, Nono; Sole, Xavier; Hernandez, Pilar; Lazaro, Conxi; Nathanson, Katherine L; Weber, Barbara L; Cusick, Michael E; Hill, David E; Offit, Kenneth; Livingston, David M; Gruber, Stephen B; Parvin, Jeffrey D; Vidal, Marc
2007 Nov;39(11):1338-1349, Nature genetics
— id: 128898, year: 2007, vol: 39, page: 1338, stat: Journal Article,

MDM2 SNP309 accelerates tumor formation in a gender-specific and hormone-dependent manner
Bond, Gareth L; Hirshfield, Kim M; Kirchhoff, Tomas; Alexe, Gabriella; Bond, Elisabeth E; Robins, Harlan; Bartel, Frank; Taubert, Helge; Wuerl, Peter; Hait, William; Toppmeyer, Deborah; Offit, Kenneth; Levine, Arnold J
2006 May 15;66(10):5104-5110, Cancer research
— id: 128900, year: 2006, vol: 66, page: 5104, stat: Journal Article,

Localization of breast cancer susceptibility loci by genome-wide SNP linkage disequilibrium mapping
Ellis, Nathan A; Kirchhoff, Tomas; Mitra, Nandita; Ye, Tian-Zhang; Chuai, Shaokun; Huang, Helen; Nafa, Khedoudja; Norton, Larry; Neuhausen, Susan; Gordon, Derek; Struewing, Jeffery P; Narod, Steven; Offit, Kenneth
2006 Jan;30(1):48-61, Genetic epidemilogy
— id: 128901, year: 2006, vol: 30, page: 48, stat: Journal Article,

Colorectal cancer risk in individuals with biallelic or monoallelic mutations of MYH
Peterlongo, Paolo; Mitra, Nandita; Chuai, Shaokun; Kirchhoff, Tomas; Palmer, Crystal; Huang, Helen; Nafa, Khedoudja; Offit, Kenneth; Ellis, Nathan A
2005 Apr 10;114(3):505-507, International journal of cancer
— id: 128902, year: 2005, vol: 114, page: 505, stat: Journal Article,

Functional and genomic approaches reveal an ancient CHEK2 allele associated with breast cancer in the Ashkenazi Jewish population
Shaag, Avraham; Walsh, Tom; Renbaum, Paul; Kirchhoff, Tomas; Nafa, Khedoudja; Shiovitz, Stacey; Mandell, Jessica B; Welcsh, Piri; Lee, Ming K; Ellis, Nathan; Offit, Kenneth; Levy-Lahad, Ephrat; King, Mary-Claire
2005 Feb 15;14(4):555-563, Human molecular genetics
— id: 128903, year: 2005, vol: 14, page: 555, stat: Journal Article,

BRCA mutations and risk of prostate cancer in Ashkenazi Jews
Kirchhoff, Tomas; Kauff, Noah D; Mitra, Nandita; Nafa, Kedoudja; Huang, Helen; Palmer, Crystal; Gulati, Tony; Wadsworth, Eve; Donat, Sheri; Robson, Mark E; Ellis, Nathan A; Offit, Kenneth
2004 May 1;10(9):2918-2921, Clinical cancer research
— id: 128905, year: 2004, vol: 10, page: 2918, stat: Journal Article,

Frequency of BRCA1 and BRCA2 mutations in unselected Ashkenazi Jewish patients with colorectal cancer
Kirchhoff, Tomas; Satagopan, Jaya M; Kauff, Noah D; Huang, Helen; Kolachana, Prema; Palmer, Crystal; Rapaport, Hannah; Nafa, Khedoudja; Ellis, Nathan A; Offit, Kenneth
2004 Jan 7;96(1):68-70, Journal of the National Cancer Institute
— id: 128906, year: 2004, vol: 96, page: 68, stat: Journal Article,

Localization of cancer susceptibility genes by genome-wide single-nucleotide polymorphism linkage-disequilibrium mapping
Mitra, Nandita; Ye, Tian-Zhang; Smith, Alex; Chuai, Shaokun; Kirchhoff, Tomas; Peterlongo, Paolo; Nafa, Khedoudja; Phillips, Michael S; Offit, Kenneth; Ellis, Nathan A
2004 Nov 1;64(21):8116-8125, Cancer research
— id: 128904, year: 2004, vol: 64, page: 8116, stat: Journal Article,

A636P is associated with early-onset colon cancer in Ashkenazi Jews
Guillem, Jose G; Rapaport, Beth S; Kirchhoff, Tomas; Kolachana, Prema; Nafa, Khedoudja; Glogowski, Emily; Finch, Rob; Huang, Helen; Foulkes, William D; Markowitz, Arnold; Ellis, Nathan A; Offit, Kenneth
2003 Feb;196(2):222-225, Journal of the American College of Surgeons
— id: 128907, year: 2003, vol: 196, page: 222, stat: Journal Article,

Frequency of CHEK2*1100delC in New York breast cancer cases and controls
Offit, Kenneth; Pierce, Heather; Kirchhoff, Tomas; Kolachana, Prema; Rapaport, Beth; Gregersen, Peter; Johnson, Steven; Yossepowitch, Orit; Huang, Helen; Satagopan, Jaya; Robson, Mark; Scheuer, Lauren; Nafa, Khedoudja; Ellis, Nathan
2003 Jan 15;4:1-1, BMC medical genetics
— id: 128908, year: 2003, vol: 4, page: 1, stat: Journal Article,

DNA polymerase lambda, a novel DNA repair enzyme in human cells
Garcia-Diaz, Miguel; Bebenek, Katarzyna; Sabariegos, Rosario; Dominguez, Orlando; Rodriguez, Josana; Kirchhoff, Tomas; Garcia-Palomero, Esther; Picher, Angel J; Juarez, Raquel; Ruiz, Jose F; Kunkel, Thomas A; Blanco, Luis
2002 Apr 12;277(15):13184-13191, Journal of biological chemistry
— id: 128909, year: 2002, vol: 277, page: 13184, stat: Journal Article,

BLM heterozygosity and the risk of colorectal cancer
Gruber, Stephen B; Ellis, Nathan A; Scott, Karen K; Almog, Ronit; Kolachana, Prema; Bonner, Joseph D; Kirchhoff, Tomas; Tomsho, Lynn P; Nafa, Khedoudja; Pierce, Heather; Low, Marcelo; Satagopan, Jaya; Rennert, Hedy; Huang, Helen; Greenson, Joel K; Groden, Joanna; Rapaport, Beth; Shia, Jinru; Johnson, Stephen; Gregersen, Peter K; Harris, Curtis C; Boyd, Jeff; Rennert, Gad; Offit, Kenneth
2002 Sep 20;297(5589):2013-2013, Science
— id: 93151, year: 2002, vol: 297, page: 2013, stat: Journal Article,