Kenneth D. Carr

Biosketch / Results /

Kenneth D. Carr, Ph.D.

Professor;
Departments of Psychiatry (VA) and Biochemistry and Molecular Pharmacology

Contact Info

Address
450 East 29th street
Floor 8 Room 807
New York, NY

212-263-5749
212-263-5000
Kenneth.Carr@nyumc.org

« Back to Results

Education

— Ph.D. (Experimental Psychology) New York University, NY, NY, Graduate Education
— (Psychiatry) NYU School of Medicine, NY, NY, PostDoctoral Training

« Back to Results

Research Summary

Our laboratory has a general interest in the relationship between CNS mechanisms that regulate ingestive behavior and drug abuse, with a particular interest in neuroadaptations induced by food restriction that increase the reward magnitude of abused drugs and predispose subjects to binge-eating. In recent years we have established that unconditioned reward-related effects of numerous drugs of abuse and dopamine receptor agonists are increased by food restriction. In tissue preparations, we have identified a variety of dorsal and ventral striatal neuroadaptations that are hypothesized to mediate increased reward sensitivity and synaptic plasticity during chronic food restriction, including upregulation of D-1 dopamine receptor-mediated phosphorylation of NMDA receptor NR1 and AMPA receptor GluR1 subunits, and increased ERK 1/2 MAP kinase and CaM kinase II signaling. Current research is focused on striatal AMPA receptor trafficking and MAP kinase activation in response to palatable food and drugs of abuse, and their potential roles in the genesis of enduring maladaptive reward-directed behavior.

Research Interests

Neurobiology of Ingestive Behavior and Drug Addiction

Research Keywords

behavioral neuroscience, brain reward mechanisms, drug abuse, food restriction

« Back to Results

All data from NYU Health Sciences Library Faculty Bibliography — -

Contact:
http://hsl.med.nyu.edu/faculty-bibliography-search

Involvement of nucleus accumbens AMPA receptor trafficking in augmentation of D- amphetamine reward in food-restricted rats
Peng, Xing-Xiang; Cabeza de Vaca, Soledad; Ziff, Edward B; Carr, Kenneth D
2014 Feb;:538-544, Psychopharmacology
— id: 900402, year: 2014, vol: , page: 538, stat: Journal Article,

Sucrose ingestion induces rapid AMPA receptor trafficking
Tukey, David S; Ferreira, Jainne M; Antoine, Shannon O; D'amour, James A; Ninan, Ipe; Cabeza de Vaca, Soledad; Incontro, Salvatore; Wincott, Charlotte; Horwitz, Julian K; Hartner, Diana T; Guarini, Carlo B; Khatri, Latika; Goffer, Yossef; Xu, Duo; Titcombe, Roseann F; Khatri, Megna; Marzan, Dave S; Mahajan, Shahana S; Wang, Jing; Froemke, Robert C; Carr, Kenneth D; Aoki, Chiye; Ziff, Edward B
2013 Apr;33(14):6123-6132, Journal of neuroscience
— id: 271462, year: 2013, vol: 33, page: 6123, stat: Journal Article,

Effects of time of feeding on psychostimulant reward, conditioned place preference, metabolic hormone levels, and nucleus accumbens biochemical measures in food-restricted rats
Zheng, Danielle; Liu, Shan; Cabeza de Vaca, Soledad; Carr, Kenneth D
2013 May;227(2):307-320, Psychopharmacology
— id: 315862, year: 2013, vol: 227, page: 307, stat: Journal Article,

Effects of protein kinase A inhibitor and activator on rewarding effects of SKF-82958 microinjected into nucleus accumbens shell of ad libitum fed and food-restricted rats
de Vaca, Soledad Cabeza; Peng, Xing-Xiang; Concors, Seth; Farin, Casey; Lascu, Elena; Carr, Kenneth D
2012 Jun;221(4):589-599, Psychopharmacology
— id: 167794, year: 2012, vol: 221, page: 589, stat: Journal Article,

Food restriction increases acquisition, persistence and drug prime-induced expression of a cocaine-conditioned place preference in rats
Zheng, Danielle; de Vaca, Soledad Cabeza; Carr, Kenneth D
2012 Jan;100(3):538-544, Pharmacology biochemistry & behavior
— id: 147686, year: 2012, vol: 100, page: 538, stat: Journal Article,

Food scarcity, neuroadaptations, and the pathogenic potential of dieting in an unnatural ecology: Binge eating and drug abuse
Carr, Kenneth D
2011 Jul 25;104(1):162-167, Physiology & behavior
— id: 134091, year: 2011, vol: 104, page: 162, stat: Journal Article,

Enhanced cocaine-conditioned place preference and associated brain regional levels of BDNF, p-ERK1/2 and p-Ser845-GluA1 in food-restricted rats
Liu S; Zheng D; Peng XX; Cabeza de Vaca S; Carr KD
2011 Jul 11;1400:31-41, Brain research
— id: 134090, year: 2011, vol: 1400, page: 31, stat: Journal Article,

A food restriction protocol that increases drug reward decreases tropomyosin receptor kinase B in the ventral tegmental area, with no effect on brain-derived neurotrophic factor or tropomyosin receptor kinase B protein levels in dopaminergic forebrain regions
Pan, Y; Chau, L; Liu, S; Avshalumov, M V; Rice, M E; Carr, K D
2011 Dec 1;197:330-338, Neuroscience
— id: 141070, year: 2011, vol: 197, page: 330, stat: Journal Article,

Effects of food restriction and sucrose intake on synaptic delivery of AMPA receptors in nucleus accumbens
Peng XX; Ziff EB; Carr KD
2011 Oct;65(10):1024-1031, Synapse
— id: 134092, year: 2011, vol: 65, page: 1024, stat: Journal Article,

SKF-83566, a D(1) -dopamine receptor antagonist, inhibits the dopamine transporter
Stouffer, Melissa A; Ali, Solav; Reith, Maarten E A; Patel, Jyoti C; Sarti, Federica; Carr, Kenneth D; Rice, Margaret E
2011 Sep;118(5):714-720, Journal of neurochemistry
— id: 136635, year: 2011, vol: 118, page: 714, stat: Journal Article,

AMPA receptor subunit GluR1 downstream of D-1 dopamine receptor stimulation in nucleus accumbens shell mediates increased drug reward magnitude in food-restricted rats
Carr, K D; Chau, L S; Cabeza de Vaca, S; Gustafson, K; Stouffer, M; Tukey, D S; Restituito, S; Ziff, E B
2010 Feb 17;165(4):1074-1086, Neuroscience
— id: 106493, year: 2010, vol: 165, page: 1074, stat: Journal Article,

Reward-potentiating effects of D-1 dopamine receptor agonist and AMPAR GluR1 antagonist in nucleus accumbens shell and their modulation by food restriction
Carr, Kenneth D; Cabeza de Vaca, Soledad; Sun, Yanjie; Chau, Lily S
2009 Mar;202(4):731-743, Psychopharmacology
— id: 96114, year: 2009, vol: 202, page: 731, stat: Journal Article,

Effects of the MEK inhibitor, SL-327, on rewarding, motor- and cellular-activating effects of D-amphetamine and SKF-82958, and their augmentation by food restriction in rat
Carr, Kenneth D; de Vaca, Soledad Cabeza; Sun, Yanjie; Chau, Lily S; Pan, Yan; Dela Cruz, Julie
2009 Jan;201(4):495-506, Psychopharmacology
— id: 111779, year: 2009, vol: 201, page: 495, stat: Journal Article,

The adenosine A2A receptor agonist, CGS-21680, blocks excessive rearing, acquisition of wheel running, and increases nucleus accumbens CREB phosphorylation in chronically food-restricted rats
Cabeza de Vaca, Soledad; Kannan, Pavitra; Pan, Yan; Jiang, Nancy; Sun, Yanjie; Carr, Kenneth D
2007 Apr 20;1142:100-109, Brain research
— id: 72863, year: 2007, vol: 1142, page: 100, stat: Journal Article,

Chronic food restriction: Enhancing effects on drug reward and striatal cell signaling
Carr, Kenneth D
2007 ;91(5):459-472, Physiology & behavior
— id: 69632, year: 2007, vol: 91, page: 459, stat: Journal Article,

Role of alpha(1)-Adrenoceptors of the Locus Coeruleus in Self-Stimulation of the Medial Forebrain Bundle
Lin, Yan; de Vaca, Soledad Cabeza; Carr, Kenneth D; Stone, Eric A
2007 Apr;32(4):835-841, Neuropsychopharmacology
— id: 69634, year: 2007, vol: 32, page: 835, stat: Journal Article,

Effects of central leptin infusion on the reward-potentiating effect of D-amphetamine
Hao, Joy; Cabeza de Vaca, Soledad; Pan, Yan; Carr, Kenneth D
2006 May 4;1087(1):123-133, Brain research
— id: 67847, year: 2006, vol: 1087, page: 123, stat: Journal Article,

Synthesis, protein levels, activity, and phosphorylation state of tyrosine hydroxylase in mesoaccumbens and nigrostriatal dopamine pathways of chronically food-restricted rats
Pan, Yan; Berman, Yemiliya; Haberny, Sandra; Meller, Emanuel; Carr, Kenneth D
2006 Nov 29;1122(1):135-142, Brain research
— id: 69633, year: 2006, vol: 1122, page: 135, stat: Journal Article,

Striatal cell signaling in chronically food-restricted rats under basal conditions and in response to brief handling
Pan, Yan; Siregar, Ermanda; Carr, Kenneth D
2006 Jan 30;393(2-3):243-248, Neuroscience letters
— id: 62808, year: 2006, vol: 393, page: 243, stat: Journal Article,

Chronic food restriction and dopamine transporter function in rat striatum
Zhen, Juan; Reith, Maarten E A; Carr, Kenneth D
2006 Apr 12;1082(1):98-101, Brain research
— id: 68807, year: 2006, vol: 1082, page: 98, stat: Journal Article,

Feeding, body weight, and sensitivity to non-ingestive reward stimuli during and after 12-day continuous central infusions of melanocortin receptor ligands
Cabeza de Vaca, S; Hao, J; Afroz, T; Krahne, L L; Carr, K D
2005 Nov;26(11):2314-2321, Peptides
— id: 62738, year: 2005, vol: 26, page: 2314, stat: Journal Article,

Food restriction increases NMDA receptor-mediated calcium-calmodulin kinase II and NMDA receptor/extracellular signal-regulated kinase 1/2-mediated cyclic amp response element-binding protein phosphorylation in nucleus accumbens upon D-1 dopamine receptor stimulation in rats
Haberny, S L; Carr, K D
2005 ;132(4):1035-1043, Neuroscience
— id: 56355, year: 2005, vol: 132, page: 1035, stat: Journal Article,

Comparison of basal and D-1 dopamine receptor agonist-stimulated neuropeptide gene expression in caudate-putamen and nucleus accumbens of ad libitum fed and food-restricted rats
Haberny, Sandra L; Carr, Kenneth D
2005 Nov 30;141(2):121-127, Brain research. Molecular brain research
— id: 69635, year: 2005, vol: 141, page: 121, stat: Journal Article,

A progressive ratio schedule of self-stimulation testing in rats reveals profound augmentation of d-amphetamine reward by food restriction but no effect of a "sensitizing" regimen of d-amphetamine
Cabeza de Vaca, Soledad; Krahne, Lisa L; Carr, Kenneth D
2004 Aug;175(1):106-113, Psychopharmacology
— id: 48099, year: 2004, vol: 175, page: 106, stat: Journal Article,

Chronic food restriction increases D-1 dopamine receptor agonist-induced phosphorylation of extracellular signal-regulated kinase 1/2 and cyclic AMP response element-binding protein in caudate-putamen and nucleus accumbens
Haberny, S L; Berman, Y; Meller, E; Carr, K D
2004 ;125(1):289-298, Neuroscience
— id: 46194, year: 2004, vol: 125, page: 289, stat: Journal Article,

Effects of chronic ICV leptin infusion on motor-activating effects of D-amphetamine in food-restricted and ad libitum fed rats
Hao, J; Cabeza de Vaca, S; Carr, K D
2004 Dec 15;83(3):377-381, Physiology & behavior
— id: 47900, year: 2004, vol: 83, page: 377, stat: Journal Article,

Effects of the group I metabotropic glutamate receptor agonist, DHPG, and injection stress on striatal cell signaling in food-restricted and ad libitum fed rats
Pan, Yan; Berman, Yemiliya; Carr, Kenneth D
2004 Dec 3;5(1):50-50, BMC neuroscience
— id: 55996, year: 2004, vol: 5, page: 50, stat: Journal Article,

Evidence of the receptor for cocaine and amphetamine regulated transcript ( CART ) in GH3 cells and bovine anterior pituitary
Berman, Y.; Lukyanov, Y. S.; Tkalych, O.; Fiallo, A.; Helmer, E.; Petrenko, A.; Carr, K. D.
2003 ;2003:?-?, Society for Neuroscience Abstract Viewer & Itinerary Planner
— id: 92205, year: 2003, vol: 2003, page: ?, stat: Journal Article,

Effects of chronic ICV infusion of melanocortin receptor ligands on brain stimulation reward and the threshold - lowering effect of D - amphetamine
Cabeza de Vaca, S.; Krahne, L.; Carr, K. D.
2003 ;2003:?-?, Society for Neuroscience Abstract Viewer & Itinerary Planner
— id: 92208, year: 2003, vol: 2003, page: ?, stat: Journal Article,

Evidence of increased dopamine receptor signaling in food-restricted rats
Carr, K D; Tsimberg, Y; Berman, Y; Yamamoto, N
2003 ;119(4):1157-1167, Neuroscience
— id: 39172, year: 2003, vol: 119, page: 1157, stat: Journal Article,

Food restriction upregulates D-1 dopamine receptor-mediated MAP kinase signaling in caudate-putamen and nucleus accumbens
Haberny, S. L.; Berman, Y.; Meller, E.; Carr, K. D.
2003 ;2003:?-?, Society for Neuroscience Abstract Viewer & Itinerary Planner
— id: 92207, year: 2003, vol: 2003, page: ?, stat: Journal Article,

Chronic cocaine administration alters immunoreactive cocaine and amphetamine regulated transcript levels in specific rat brain regions
Lukyanov, Y. S.; Tkalych, O.; Helmer, E.; Fiallo, A.; Carr, K. D.; Berman, Y.
2003 ;2003:?-?, Society for Neuroscience Abstract Viewer & Itinerary Planner
— id: 92206, year: 2003, vol: 2003, page: ?, stat: Journal Article,

THE THRESHOLD - LOWERING EFFECT OF COCAINE ON LATERAL HYPOTHALAMIC SELF - STIMULATION IS ENHANCED BY THE MELANOCORTIN RECEPTOR AGONIST, MTII
Cabeza de Vaca, S.; Krahne, L. L.; Carr, K. D.
2002 ;2002:?-?, Society for Neuroscience Abstract Viewer & Itinerary Planner
— id: 92209, year: 2002, vol: 2002, page: ?, stat: Journal Article,

The melanocortin receptor agonist MTII augments the rewarding effect of amphetamine in ad-libitum-fed and food-restricted rats
Cabeza de Vaca, Soledad; Kim, Gye-Young; Carr, Kenneth D
2002 Apr;161(1):77-85, Psychopharmacology
— id: 39670, year: 2002, vol: 161, page: 77, stat: Journal Article,

Effects of the D(3) dopamine receptor antagonist, U99194A, on brain stimulation and d-amphetamine reward, motor activity, and c-fos expression in ad libitum fed and food-restricted rats
Carr, K D; Yamamoto, N; Omura, M; Cabeza de Vaca, S; Krahne, L
2002 Aug;163(1):76-84, Psychopharmacology
— id: 39605, year: 2002, vol: 163, page: 76, stat: Journal Article,

Augmentation of drug reward by chronic food restriction. Behavioral evidence and underlying mechanisms
Carr, Kenneth D
2002 Jul;76(3):353-364, Physiology & behavior
— id: 32240, year: 2002, vol: 76, page: 353, stat: Journal Article,

EFFECT OF CHRONIC FOOD RESTRICTION ON QUINPIROLE-STIMULATED (35S)GTPgammaS BINDING IN RAT STRIATUM
Tsimberg, Y.; Berman, Y.; Carr, K.
2002 ;2002:?-?, Society for Neuroscience Abstract Viewer & Itinerary Planner
— id: 92210, year: 2002, vol: 2002, page: ?, stat: Journal Article,

Rewarding and locomotor-activating effects of direct dopamine receptor agonists are augmented by chronic food restriction in rats
Carr KD; Kim GY; Cabeza de Vaca S
2001 Apr;154(4):420-428, Psychopharmacology
— id: 20668, year: 2001, vol: 154, page: 420, stat: Journal Article,

Repeated treatment with antidepressants differentially alters 5-HT1A agonist-stimulated (35S)GTPgammaS binding in rat brain regions
Shen, C. P.; Carr, K. D.; Meller, E.
2001 ;27(1):995-995, Abstracts (Society for Neuroscience)
— id: 92211, year: 2001, vol: 27, page: 995, stat: Journal Article,

Hypoinsulinemia may mediate the lowering of self-stimulation thresholds by food restriction and streptozotocin-induced diabetes
Carr KD; Kim G; Cabeza de Vaca S
2000 Apr 28;863(1-2):160-168, Brain research
— id: 11742, year: 2000, vol: 863, page: 160, stat: Journal Article,

Chronic food restriction in rats augments the central rewarding effect of cocaine and the delta1 opioid agonist, DPDPE, but not the delta2 agonist, deltorphin-II
Carr KD; Kim GY; Cabeza de Vaca S
2000 Oct;152(2):200-207, Psychopharmacology
— id: 39527, year: 2000, vol: 152, page: 200, stat: Journal Article,

Chronic food restriction increases fos-like immunoreactivity (FLI) induced in rat forebrain by intraventricular amphetamine
Carr KD; Kutchukhidze N
2000 Apr 7;861(1):88-96, Brain research
— id: 11773, year: 2000, vol: 861, page: 88, stat: Journal Article,

Effect of chronic food restriction on Fos-like immunoreactivity (FLI) induced in rat brain regions by intraventricular MK-801
Carr KD; Kutchukhidze N
2000 Aug 11;873(2):283-286, Brain research
— id: 11562, year: 2000, vol: 873, page: 283, stat: Journal Article,

Effects of chronic food restriction on locomotion, reward and c-fos expression induced by D-1 and D-2 dopamine agonists
Carr, K. D.; Cabeza de Vaca, S.; Kutchukhidze, N.; Kim, G. Y.
2000 ;26(1-2):?-?, Abstracts (Society for Neuroscience)
— id: 92212, year: 2000, vol: 26, page: ?, stat: Journal Article,

5-Hydroxytryptamine(1A) receptor-stimulated [(35)S]GTPgammaS binding in rat brain: absence of regional differences in coupling efficiency
Meller E; Li H; Carr KD; Hiller JM
2000 Feb;292(2):684-691, Journal of pharmacology & experimental therapeutics
— id: 11861, year: 2000, vol: 292, page: 684, stat: Journal Article,

CRF antagonist reverses the potentiation of amphetamine reward by food restriction
Cabeza de Vaca, S.; Carr, K. D.
1999 ;25(1-2):2082-2082, Abstracts (Society for Neuroscience)
— id: 92213, year: 1999, vol: 25, page: 2082, stat: Journal Article,

Differential effects of mu and kappa opioid antagonists on Fos-like immunoreactivity in extended amygdala
Carr KD; Kutchukhidze N; Park TH
1999 Mar 20;822(1-2):34-42, Brain research
— id: 6063, year: 1999, vol: 822, page: 34, stat: Journal Article,

Increased site-specific phosphorylation of tyrosine hydroxylase accompanies stimulation of enzymatic activity induced by cessation of dopamine neuronal activity
Lew JY; Garcia-Espana A; Lee KY; Carr KD; Goldstein M; Haycock JW; Meller E
1999 Feb;55(2):202-209, Molecular pharmacology
— id: 7388, year: 1999, vol: 55, page: 202, stat: Journal Article,

Cloning and characterization of a mu opioid receptor from bovine brain
Onoprishvili, I.; Andria, M. L.; Vilim, S. S.; Hiller, J. M.; Carr, K. D.; Simon, E. J.
1999 ;25(1-2):1476-1476, Abstracts (Society for Neuroscience)
— id: 92214, year: 1999, vol: 25, page: 1476, stat: Journal Article,

Food restriction enhances the central rewarding effect of abused drugs
Cabeza de Vaca S; Carr KD
1998 Sep 15;18(18):7502-7510, Journal of neuroscience
— id: 8024, year: 1998, vol: 18, page: 7502, stat: Journal Article,

A search for the metabolic signal that sensitizes lateral hypothalamic self-stimulation in food-restricted rats
Cabeza De Vaca S; Holiman S; Carr KD
1998 Jun 1;64(3):251-260, Physiology & behavior
— id: 8025, year: 1998, vol: 64, page: 251, stat: Journal Article,

Food restriction sensitizes the neural substrate for drug reward
Cabeza De Vaca, S.; Carr, K. D.
1998 ;24(1-2):1964-1964, Abstracts (Society for Neuroscience)
— id: 92215, year: 1998, vol: 24, page: 1964, stat: Journal Article,

Effect of adrenalectomy on cocaine facilitation of medial prefrontal cortex self-stimulation
Carr KD; Abrahamsen GC
1998 Mar 23;787(2):321-327, Brain research
— id: 7523, year: 1998, vol: 787, page: 321, stat: Journal Article,

Neuroanatomical patterns of Fos-like immunoreactivity induced by naltrexone in food-restricted and ad libitum fed rats
Carr KD; Park TH; Zhang Y; Stone EA
1998 Jan 1;779(1-2):26-32, Brain research
— id: 7524, year: 1998, vol: 779, page: 26, stat: Journal Article,

Effects of an intrahypothalamic injection of antisense oligonucleotides for preproenkephalin mRNA in female rats: evidence for opioid involvement in lordosis reflex (vol 777, pg 60, 1997)
Nicot, A; Ogawa, S; Berman, Y; Carr, KD; Pfaff, DW
1998 NOV 2 ;809(2):337-337, Brain research
— id: 53680, year: 1998, vol: 809, page: 337, stat: Journal Article,

Neuroanatomical patterns of fos-like immunoreactivity induced by a palatable meal and meal-paired environment in saline- and naltrexone-treated rats
Park TH; Carr KD
1998 Sep 14;805(1-2):169-180, Brain research
— id: 7422, year: 1998, vol: 805, page: 169, stat: Journal Article,

Neuroanatomical patterns of Fos-like immunoreactivity induced by a palatable meal and meal-paired environment in saline- and naltrexone-treated rats
Park, T. H.; Carr, K. D.
1998 ;24(1-2):706-706, Abstracts (Society for Neuroscience)
— id: 92216, year: 1998, vol: 24, page: 706, stat: Journal Article,

Effect of adrenalectomy on cocaine facilitation of lateral hypothalamic self-stimulation
Abrahamsen GC; Carr KD
1997 Apr 25;755(1):156-161, Brain research
— id: 7097, year: 1997, vol: 755, page: 156, stat: Journal Article,

Aminoglutethimide, a corticosteroid synthesis inhibitor, facilitates brain stimulation reward in food-restricted rats: an investigation of underlying mechanisms
Abrahamsen GC; Kandawire MJ; Carr KD
1997 Oct;133(4):405-412, Psychopharmacology
— id: 12179, year: 1997, vol: 133, page: 405, stat: Journal Article,

Effect of adrenalectomy on cocaine's facilitation of medial prefrontal cortex self-stimulation
Abrahamsen, G. C.; Ladigoski, J. M.; Carr, K. D.
1997 ;23(1-2):2146-2146, Abstracts (Society for Neuroscience)
— id: 92217, year: 1997, vol: 23, page: 2146, stat: Journal Article,

Chronic food restriction and streptozotocin-induced diabetes differentially alter prodynorphin mRNA levels in rat brain regions
Berman Y; Devi L; Spangler R; Kreek MJ; Carr KD
1997 Jun;46(1-2):25-30, Brain research. Molecular brain research
— id: 7114, year: 1997, vol: 46, page: 25, stat: Journal Article,

C-fos activation by naltrexone in food-restricted and ad libitum fed rats
Carr, K. D.; Park, T. H.; Zhang, Y.; Stone, E. A.
1997 ;23(1-2):517-517, Abstracts (Society for Neuroscience)
— id: 92218, year: 1997, vol: 23, page: 517, stat: Journal Article,

Effects of an intrahypothalamic injection of antisense oligonucleotides for preproenkephalin mRNA in female rats: evidence for opioid involvement in lordosis reflex [published erratum appears in Brain Res 1998 Nov 2;809(2):337]
Nicot A; Ogawa S; Berman Y; Carr KD; Pfaff DW
1997 Nov 28;777(1-2):60-68, Brain research
— id: 7710, year: 1997, vol: 777, page: 60, stat: Journal Article,

Blockade of estradiol-induced hypothalamic enkephalin expression by antisense oligonucleotides reduces lordosis reflex in female rats
Nicot, A.; Ogawa, S.; Berman, Y.; Carr, K. D.; Pfaff, D. W.
1997 ;23(1-2):124-124, Abstracts (Society for Neuroscience)
— id: 92219, year: 1997, vol: 23, page: 124, stat: Journal Article,

Effects of corticosteroid synthesis inhibitors on the sensitization of reward by food restriction
Abrahamsen GC; Carr KD
1996 Jul 8;726(1-2):39-48, Brain research
— id: 12580, year: 1996, vol: 726, page: 39, stat: Journal Article,

Examination of aminoglutethimide induced sensitization of lateral hypothalamic self-stimulation (LHSS) in food restricted rats
Abrahamsen, G. C.; Kandawire, M.; Carr, K. D.
1996 ;22(1-3):685-685, Abstracts (Society for Neuroscience)
— id: 92220, year: 1996, vol: 22, page: 685, stat: Journal Article,

Haloperidol antagonism of cue-elicited cocaine craving
Berger, S P; Hall, S; Mickalian, J D; Reid, M S; Crawford, C A; Delucchi, K; Carr, K; Hall, S
1996 Feb 24;347(9000):504-508, Lancet
— id: 109300, year: 1996, vol: 347, page: 504, stat: Journal Article,

Feeding, drug abuse, and the sensitization of reward by metabolic need
Carr KD
1996 Nov;21(11):1455-1467, Neurochemical research
— id: 12487, year: 1996, vol: 21, page: 1455, stat: Journal Article,

Opioid receptor types and stimulation-induced feeding
Carr KD
Drug receptor subtypes and ingestive behavior London : Academic Press, 1996,
— id: 3428, year: 1996, vol: , page: 167, stat: Chapter,

Diabetes alters mu and kappa opioid binding in rat brain regions: comparison with effects of food restriction
Wolinsky TD; Abrahamsen GC; Carr KD
1996 Oct 28;738(1):167-171, Brain research
— id: 12511, year: 1996, vol: 738, page: 167, stat: Journal Article,

Chronic food restriction alters mu and kappa opioid receptor binding in the parabrachial nucleus of the rat: a quantitative autoradiographic study
Wolinsky TD; Carr KD; Hiller JM; Simon EJ
1996 Jan 15;706(2):333-336, Brain research
— id: 8089, year: 1996, vol: 706, page: 333, stat: Journal Article,

Curve-shift analysis of self-stimulation in food-restricted rats: relationship between daily meal, plasma corticosterone and reward sensitization
Abrahamsen GC; Berman Y; Carr KD
1995 Oct 16;695(2):186-194, Brain research
— id: 6882, year: 1995, vol: 695, page: 186, stat: Journal Article,

Effects of streptozotocin-induced diabetes on prodynorphin-derived peptides in rat brain regions
Berman Y; Devi L; Carr KD
1995 Jul 10;685(1-2):129-134, Brain research
— id: 6887, year: 1995, vol: 685, page: 129, stat: Journal Article,

Repeated inescapable stress produces a neuroleptic-like effect on the conditioned avoidance response
Friedhoff AJ; Carr KD; Uysal S; Schweitzer J
1995 Oct;13(2):129-138, Neuropsychopharmacology
— id: 6826, year: 1995, vol: 13, page: 129, stat: Journal Article,

Massive activation of c-fos in forebrain after mechanical stimulation of the locus coeruleus
Stone EA; Zhang Y; Carr KD
1995 ;36(1):77-80, Brain research bulletin
— id: 12831, year: 1995, vol: 36, page: 77, stat: Journal Article,

Effects of chronic food restriction on prodynorphin-derived peptides in rat brain regions
Berman Y; Devi L; Carr KD
1994 Nov 21;664(1-2):49-53, Brain research
— id: 6573, year: 1994, vol: 664, page: 49, stat: Journal Article,

Regional distribution of neuropeptide processing endopeptidases in adult rat brain
Berman YL; Rattan AK; Carr K; Devi L
1994 ;76(3-4):245-250, Biochimie
— id: 6574, year: 1994, vol: 76, page: 245, stat: Journal Article,

Effects of chronic food restriction on prodynorphin-derived peptides in rat brain regions
Berman, Y.; Devi, L.; Carr, K. D.
1994 ;20(1-2):752-752, Abstracts (Society for Neuroscience)
— id: 92222, year: 1994, vol: 20, page: 752, stat: Journal Article,

Endogenous opioid modulation of reward in food-restricted and diabetic rats
Carr KD
1994 ;54(1):43-44, Regulatory peptides
— id: 8100, year: 1994, vol: 54, page: 43, stat: Journal Article,

Streptozotocin-induced diabetes produces a naltrexone-reversible lowering of self-stimulation threshold
Carr KD
1994 Nov 21;664(1-2):211-214, Brain research
— id: 6588, year: 1994, vol: 664, page: 211, stat: Journal Article,

The role of multiple opioid receptors in the potentiation of reward by food restriction
Carr KD; Papadouka V
1994 Mar 14;639(2):253-260, Brain research
— id: 7881, year: 1994, vol: 639, page: 253, stat: Journal Article,

Regulation of feeding by multiple opioid receptors in cingulate cortex; follow-up to an in vivo autoradiographic study
Carr KD; Wolinsky TD
1994 Mar;26(3):207-213, Neuropeptides
— id: 7880, year: 1994, vol: 26, page: 207, stat: Journal Article,

The role of multiple opioid receptors in the maintenance of stimulation-induced feeding
Papadouka V; Carr KD
1994 Mar 7;639(1):42-48, Brain research
— id: 6478, year: 1994, vol: 639, page: 42, stat: Journal Article,

Effects of chronic food restriction on mu and kappa opioid binding in rat forebrain: a quantitative autoradiographic study
Wolinsky TD; Carr KD; Hiller JM; Simon EJ
1994 Sep 12;656(2):274-280, Brain research
— id: 6781, year: 1994, vol: 656, page: 274, stat: Journal Article,

Effect of chronic food restriction on regional Kappa opioid receptor binding in the rat: A quantitative autoradiographic study
Wolinsky, T. D.; Carr, K. D.; Hiller, J. M.; Simon, E. J.
1994 ;20(1-2):752-752, Abstracts (Society for Neuroscience)
— id: 92221, year: 1994, vol: 20, page: 752, stat: Journal Article,

Distribution and characterization of a neuropeptide processing enzyme in adult rat brain
Berman, E.; Carr, K.; Fricker, L. D.; Devi, L.
1993 ;19(1-3):1362-1362, Abstracts (Society for Neuroscience)
— id: 92223, year: 1993, vol: 19, page: 1362, stat: Journal Article,

Norbinaltorphimine blocks the feeding but not the reinforcing effect of lateral hypothalamic electrical stimulation
Carr KD; Papadouka V; Wolinsky TD
1993 ;111(3):345-350, Psychopharmacology
— id: 7879, year: 1993, vol: 111, page: 345, stat: Journal Article,

Chronic food restriction and weight loss produce opioid facilitation of perifornical hypothalamic self-stimulation
Carr KD; Wolinsky TD
1993 Apr 2;607(1-2):141-148, Brain research
— id: 13189, year: 1993, vol: 607, page: 141, stat: Journal Article,

Chronic food restriction produces mu and kappa opioid facilitation of reward
Carr, K.; Papadouka, V.
1993 ;19(1-3):809-809, Abstracts (Society for Neuroscience)
— id: 92225, year: 1993, vol: 19, page: 809, stat: Journal Article,

The effect of chronic food restriction on mu opioid receptors in the rat: A quantitative autoradiographic study
Wolinsky, T. D.; Carr, K.; Hiller, J. M.; Simon, E. J.
1993 ;19(1-3):1154-1154, Abstracts (Society for Neuroscience)
— id: 92224, year: 1993, vol: 19, page: 1154, stat: Journal Article,

BRAIN OPIOID MECHANISMS THAT REGULATE INGESTIVE BEHAVIOR
CARR, KD
1992 DEC ;19(3):307-307, Appetite
— id: 54401, year: 1992, vol: 19, page: 307, stat: Journal Article,

MU OPIOID ACTIVITY IN MEDIAL THALAMUS EFFECTS ON BEHAVIOR AND DOPAMINE UTILIZATION
CARR K D; UYSAL S; SHWEITER J W; FRIEDHOFF A J
1991 ;17(1-2):1540-1540, Abstracts (Society for Neuroscience)
— id: 92226, year: 1991, vol: 17, page: 1540, stat: Journal Article,

Effects of parabrachial opioid antagonism on stimulation-induced feeding
Carr KD; Aleman DO; Bak TH; Simon EJ
1991 Apr 5;545(1-2):283-286, Brain research
— id: 14069, year: 1991, vol: 545, page: 283, stat: Journal Article,

EFFECTS OF NOCICEPTIVE AND PSYCHOSOCIAL STRESSORS ON REGIONAL DOPAMINE UTILIZATION
UYSAL S; CARR K D; SCHWEITZER J W; FRIEDHOFF A J
1991 ;17(1-2):503-503, Abstracts (Society for Neuroscience)
— id: 92227, year: 1991, vol: 17, page: 503, stat: Journal Article,

MU OPIOID ACTIVITY IN ANTERIOR CINGULATE CORTEX MAY MEDIATE STIMULATION-INDUCED FEEDING
WOLINSKY T; GILADY D; CARR K D
1991 ;17(1-2):492-492, Abstracts (Society for Neuroscience)
— id: 92228, year: 1991, vol: 17, page: 492, stat: Journal Article,

PARABRACHIAL OPIOID ANTAGONISM BLOCKS STIMULATION-INDUCED FEEDING
CARR K D; ALEMAN D
1990 ;16(1):775-775, Abstracts (Society for Neuroscience)
— id: 92229, year: 1990, vol: 16, page: 775, stat: Journal Article,

Effects of antibodies to dynorphin A and beta-endorphin on lateral hypothalamic self-stimulation in ad libitum fed and food-deprived rats
Carr KD
1990 Nov 26;534(1-2):8-14, Brain research
— id: 11479, year: 1990, vol: 534, page: 8, stat: Journal Article,

Potentiation of reward by food deprivation is blocked by antibodies to dynorphin A
Carr KD
1990 ;105:551-552, NIDA research monograph series
— id: 14230, year: 1990, vol: 105, page: 551, stat: Journal Article,

Rostral and caudal ventricular infusion of antibodies to dynorphin A(1-17) and dynorphin A(1-8): effects on electrically-elicited feeding in the rat
Carr, K D; Bak, T H
1990 Jan;507(2):289-294, Brain research
— id: 582322, year: 1990, vol: 507, page: 289, stat: Journal Article,

Brain stimulation-induced feeding alters regional opioid receptor binding in the rat: an in vivo autoradiographic study
Stein EA; Carr KD; Simon EJ
1990 Nov 19;533(2):213-222, Brain research
— id: 62163, year: 1990, vol: 533, page: 213, stat: Journal Article,

Stimulus induced feeding alters regional opiate receptor binding in the rat: an in vivo audioradiographic study
Stein EA; Carr KD; Simon EJ
1990 ;328:187-190, Progress in clinical & biological research
— id: 63632, year: 1990, vol: 328, page: 187, stat: Journal Article,

Stereotypies elicited by injection of N-propylnorapomorphine into striatal subregions and nucleus accumbens
Bordi F; Carr KD; Meller E
1989 Jun 12;489(2):205-215, Brain research
— id: 10586, year: 1989, vol: 489, page: 205, stat: Journal Article,

Effects of the selective kappa opioid antagonist, nor-binaltorphimine, on electrically-elicited feeding in the rat
Carr KD; Bak TH; Simon EJ; Portoghese PS
1989 ;45(19):1787-1792, Life sciences
— id: 10828, year: 1989, vol: 45, page: 1787, stat: Journal Article,

Central nervous system opioid mechanisms that mediate stimulation-induced feeding in the rat
Carr, KD
1989 ;575:503-505, Annals of the New York Academy of Sciences
— id: 584302, year: 1989, vol: 575, page: 503, stat: Journal Article,

CENTRAL-NERVOUS-SYSTEM OPIOID MECHANISMS THAT MEDIATE STIMULATION-INDUCED FEEDING IN THE RAT
Carr, KD
1989 Dec 18;575(4):503-505, Annals of the New York Academy of Sciences
— id: 31885, year: 1989, vol: 575, page: 503, stat: Journal Article,

Pharmacokinetics of [3H]-buprenorphine in the rat
Holland MJ; Carr KD; Simon EJ
1989 Apr;64(1):3-16, Research communications in chemical pathology & pharmacology
— id: 10690, year: 1989, vol: 64, page: 3, stat: Journal Article,

CNS REGIONAL CHANGES IN TRITIATED DIPRENORPHINE BINDING FOLLOWING ELECTRICALLY ELICITED FEEDING IN THE RAT
STEIN E A; CARR K D; SIMON E J
1989 ;15(1):896-896, Abstracts (Society for Neuroscience)
— id: 92230, year: 1989, vol: 15, page: 896, stat: Journal Article,

OPPOSITE EFFECTS OF ROSTRAL AND CAUDAL VENTRICULAR INFUSION OF NOR-BINALTORPHIMINE ON STIMULATION-INDUCED FEEDING
BAK T; CARR K D; SIMON E J; PORTOGHESE P S
1988 ;14(2):1107-1107, Abstracts (Society for Neuroscience)
— id: 92231, year: 1988, vol: 14, page: 1107, stat: Journal Article,

ANTIBODIES TO DYNORPHIN A 1-8 AND 1-17 ELEVATE THRESHOLD FOR BRAIN STIMULATION-INDUCED FEEDING IN RAT
CARR K D; BAK T H; SIMON E J
1988 ;14(2):1107-1107, Abstracts (Society for Neuroscience)
— id: 92232, year: 1988, vol: 14, page: 1107, stat: Journal Article,

Medial thalamic injection of opioid agonists: mu-agonist increases while kappa-agonist decreases stimulus thresholds for pain and reward
Carr KD; Bak TH
1988 Feb 16;441(1-2):173-184, Brain research
— id: 11182, year: 1988, vol: 441, page: 173, stat: Journal Article,

Regulation of electrically elicited feeding in the rat by CNS opioid peptides
Carr KD; Simon EJ
Regulatory roles of opioid peptides Weinheim : VCH Publishers, 1988,
— id: 3427, year: 1988, vol: , page: 378, stat: Chapter,

ANTIBODIES TO DYNORPHIN A 1-13 BUT NOT BETA ENDORPHIN INHIBIT ELECTRICALLY-ELICITED FEEDING IN THE RAT
CARR K D; BAK T H; GIOANNIN T L; SIMON E J
1987 ;13(2):877-877, Abstracts (Society for Neuroscience)
— id: 92233, year: 1987, vol: 13, page: 877, stat: Journal Article,

Lateral hypothalamic stimulation-produced analgesia: inferred refractory period of directly stimulated neurons and resistance to pimozide antagonism
Carr KD; Bak TH
1987 ;41(4):371-378, Physiology & behavior
— id: 11415, year: 1987, vol: 41, page: 371, stat: Journal Article,

Antibodies to dynorphin A(1-13) but not beta-endorphin inhibit electrically elicited feeding in the rat
Carr KD; Bak TH; Gioannini TL; Simon EJ
1987 Oct 6;422(2):384-388, Brain research
— id: 11344, year: 1987, vol: 422, page: 384, stat: Journal Article,

[3H]-BUPRENORPHINE DISSOCIATION FROM OPIATE RECEPTORS INVIVO
Holland, MJC; Carr, KD; Simon, EJ
1987 Mar 1;46(3):868-868, Federation proceedings (Federation of American Societies for Experimental Biology)
— id: 31267, year: 1987, vol: 46, page: 868, stat: Journal Article,

Regulation of alpha and beta components of noradrenergic cyclic AMP response in cortical slices
Stone EA; McEwen BS; Herrera AS; Carr KD
1987 Sep 23;141(3):347-356, European journal of pharmacology
— id: 11368, year: 1987, vol: 141, page: 347, stat: Journal Article,

OPPOSITE EFFECTS OF MEDIAL THALAMIC MU AND KAPPA OPIOID ACTIVITY ON MOTIVATIONAL-AFFECTIVE RESPONSES
CARR K D; SIMON E J
1986 ;12(2):939-939, Abstracts (Society for Neuroscience)
— id: 92235, year: 1986, vol: 12, page: 939, stat: Journal Article,

SYNTHESIS AND EVALUATION OF FLUORINATED DERIVATIVES OF FENTANYL AS CANDIDATES FOR OPIATE RECEPTOR STUDIES USING POSITRON EMISSION TOMOGRAPHY
HWANG, DR; FELIU, AL; WOLF, AP; MACGREGOR, RR; FOWLER, JS; ARNETT, CD; HOLLAND, MJ; CARR, K; SIMON, EJ
1986 MAR ;23(3):277-293, Journal of labelled compounds & radiopharmaceuticals
— id: 41607, year: 1986, vol: 23, page: 277, stat: Journal Article,

ROLE OF CENTRAL NORADRENERGIC AND PITUITARY ADRENAL SYSTEMS IN REGULATION OF BETA-ADRENOCEPTOR AND ALPHA-ADRENOCEPTOR FUNCTION IN RAT CENTRAL NERVOUS SYSTEM
STONE E A; MCEWEN B S; HERRERA A S; CARR K D
1986 ;12(2):1463-1463, Abstracts (Society for Neuroscience)
— id: 92234, year: 1986, vol: 12, page: 1463, stat: Journal Article,

SELECTIVE REGULATION OF BRAIN BETA-ADRENERGIC RECEPTORS BY THE NORADRENERGIC SYSTEM AND BRAIN ALPHA-ADRENERGIC RECEPTORS BY THE PITUITARY-ADRENAL SYSTEM
Stone, EA; Herrera, AS; Carr, KD; Mcewen, BS
1986 Mar 1;45(3):582-582, Federation proceedings (Federation of American Societies for Experimental Biology)
— id: 31083, year: 1986, vol: 45, page: 582, stat: Journal Article,

AVERSION-GATING SITES IN LATERAL HYPOTHALAMUS AN ANATOMIC AND PHARMACOLOGIC STUDY
CARR K D; UYSAL S
1985 ;11(2):1175-1175, Abstracts (Society for Neuroscience)
— id: 92236, year: 1985, vol: 11, page: 1175, stat: Journal Article,

Diphenhydramine potentiates narcotic but not endogenous opioid analgesia
Carr KD; Hiller JM; Simon EJ
1985 Feb;5(4-6):411-414, Neuropeptides
— id: 63644, year: 1985, vol: 5, page: 411, stat: Journal Article,

EVIDENCE OF A SUPRASPINAL OPIOID ANALGESIC MECHANISM ENGAGED BY LATERAL HYPOTHALAMIC ELECTRICAL-STIMULATION
CARR, KD; UYSAL, S
1985 ;335(1):55-62, Brain research
— id: 41224, year: 1985, vol: 335, page: 55, stat: Journal Article,

N-(3-Fluoropropyl)-N-normetazocine, a potentially useful opiate antagonist for opiate receptor studies with positron emission tomography (PET)
Feliu AL; Holland MJ; Carr KD; Fowler JS; Simon EJ
1985 Sep;49(3):323-336, Research communications in chemical pathology & pharmacology
— id: 62115, year: 1985, vol: 49, page: 323, stat: Journal Article,

The physiology of opiate hedonic effects and the role of opioids in motivated behavior
Carr KD
1984 ;3(3):5-8, Advances in alcohol & substance abuse
— id: 46860, year: 1984, vol: 3, page: 5, stat: Journal Article,

Analgesic effects of ethylketocyclazocine and morphine in rat and toad
Carr KD; Aleman DO; Holland MJ; Simon EJ
1984 Aug 27;35(9):997-1003, Life sciences
— id: 63650, year: 1984, vol: 35, page: 997, stat: Journal Article,

Potentiation of reward by hunger is opioid mediated
Carr KD; Simon EJ
1984 Apr 16;297(2):369-373, Brain research
— id: 63651, year: 1984, vol: 297, page: 369, stat: Journal Article,

Abuse of the elderly: screening and detection
Fulmer, T; Street, S; Carr, K
1984 May-Jun;10(3):131-140, Journal of emergency nursing
— id: 156261, year: 1984, vol: 10, page: 131, stat: Journal Article,

Effects of naloxone and its quarternary analogue on stimulation-induced feeding
Carr KD; Simon EJ
1983 Jan;22(1):127-130, Neuropharmacology
— id: 63657, year: 1983, vol: 22, page: 127, stat: Journal Article,

The role of opioids in feeding and reward elicited by lateral hypothalamic electrical stimulation
Carr KD; Simon EJ
1983 ;33 Suppl 1:563-566, Life sciences
— id: 63658, year: 1983, vol: 33 Suppl 1, page: 563, stat: Journal Article,

Medial thalamic lesions reduce the aversion-gating action of lateral hypothalamic stimulation
Carr KD; Bonnet KA; Simon EJ
1982 Aug 26;246(2):342-346, Brain research
— id: 63666, year: 1982, vol: 246, page: 342, stat: Journal Article,

Mu and kappa opioid agonists elevate brain stimulation threshold for escape by inhibiting aversion
Carr KD; Bonnet KA; Simon EJ
1982 Aug 12;245(2):389-393, Brain research
— id: 63667, year: 1982, vol: 245, page: 389, stat: Journal Article,

Lateral hypothalamic stimulation gates nucleus gigantocellularis-induced aversion via a reward-independent process
Carr KD; Coons EE
1982 Jan 28;232(2):293-316, Brain research
— id: 46859, year: 1982, vol: 232, page: 293, stat: Journal Article,

Rats self-administer nonrewarding brain stimulation to ameliorate aversion
Carr KD; Coons EE
1982 Mar 19;215(4539):1516-1517, Science
— id: 46858, year: 1982, vol: 215, page: 1516, stat: Journal Article,