Tony T. Huang

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Tony T. Huang, Ph.D.

Associate Professor; Co Course Director
Department of Biochemistry and Molecular Pharmacology

Contact Info

550 First Avenue
NYU medical School Floor Floor 3 Room 399
Medical Science Building
New York, NY 10016


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2003-2006 — Dana Farber Cancer Institute, Harvard Med. School, PostDoctoral Training
— University of Wisconsin, Graduate Education

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All data from NYU Health Sciences Library Faculty Bibliography — -


Co-opting the Fanconi Anemia Genomic Stability Pathway Enables Herpesvirus DNA Synthesis and Productive Growth
Karttunen, Heidi; Savas, Jeffrey N; McKinney, Caleb; Chen, Yu-Hung; Yates, John R 3rd; Hukkanen, Veijo; Huang, Tony T; Mohr, Ian
2014 Jun;:111-122, Molecular cell
— id: 1055622, year: 2014, vol: , page: 111, stat: Journal Article,

DUB-Resistant Ubiquitin to Survey Ubiquitination Switches in Mammalian Cells
Bekes, Miklos; Okamoto, Keiji; Crist, Sarah B; Jones, Mathew J; Chapman, Jessica R; Brasher, Bradley B; Melandri, Francesco D; Ueberheide, Beatrix M; Lazzerini Denchi, Eros; Huang, Tony T
2013 Nov;:826-838, Cell reports
— id: 617482, year: 2013, vol: , page: 826, stat: Journal Article,

Deubiquitinases as a Signaling Target of Oxidative Stress
Cotto-Rios, Xiomaris M; Bekes, Miklos; Chapman, Jessica; Ueberheide, Beatrix; Huang, Tony T
2012 Dec;:1475-1484, Cell reports
— id: 204152, year: 2012, vol: , page: 1475, stat: Journal Article,

Dysregulation of DNA polymerase recruitment to replication forks results in genomic instability
Jones, M J K; Colnaghi, L; Huang, T T
2012 15 Feb 2012;31(4):908-918, EMBO journal
— id: 158609, year: 2012, vol: 31, page: 908, stat: Journal Article,

The Fanconi anemia pathway in replication stress and DNA crosslink repair
Jones, Mathew J. K.; Huang, Tony T.
2012 DEC;69(23):3963-3974, Cellular & molecular life sciences: CMLS
— id: 185712, year: 2012, vol: 69, page: 3963, stat: Journal Article,

The Auto-Generated Fragment of the Usp1 Deubiquitylase Is a Physiological Substrate of the N-End Rule Pathway
Piatkov, Konstantin I; Colnaghi, Luca; Bekes, Miklos; Varshavsky, Alexander; Huang, Tony T
2012 Nov;:926-933, Molecular cell
— id: 204162, year: 2012, vol: , page: 926, stat: Journal Article,

Patient-derived C-terminal mutation of FANCI causes protein mislocalization and reveals putative EDGE motif function in DNA repair
Colnaghi, Luca; Jones, Mathew J K; Cotto-Rios, Xiomaris M; Schindler, Detlev; Hanenberg, Helmut; Huang, Tony T
2011 Feb 17;117(7):2247-2256, Blood
— id: 124093, year: 2011, vol: 117, page: 2247, stat: Journal Article,

Insights into phosphorylation-dependent mechanisms regulating USP1 protein stability during the cell cycle
Cotto Rios XM; Jones MJ; Huang TT
2011 Dec 1;10(23):4009-4016, Cell cycle
— id: 145997, year: 2011, vol: 10, page: 4009, stat: Journal Article,

APC/CCdh1-dependent proteolysis of USP1 regulates the response to UV-mediated DNA damage
Cotto-Rios, Xiomaris M; Jones, Mathew J K; Busino, Luca; Pagano, Michele; Huang, Tony T
2011 Jul 25;194(2):177-186, Journal of cell biology
— id: 135576, year: 2011, vol: 194, page: 177, stat: Journal Article,

Nuclear export of the NF-kappaB inhibitor IkappaBalpha is required for proper B cell and secondary lymphoid tissue formation
Wuerzberger-Davis, Shelly M; Chen, Yuhong; Yang, David T; Kearns, Jeffrey D; Bates, Paul W; Lynch, Candace; Ladell, Nicholas C; Yu, Mei; Podd, Andrew; Zeng, Hu; Huang, Tony T; Wen, Renren; Hoffmann, Alexander; Wang, Demin; Miyamoto, Shigeki
2011 Feb 25;34(2):188-200, Immunity
— id: 130274, year: 2011, vol: 34, page: 188, stat: Journal Article,

Calcium-dependent regulation of NEMO nuclear export in response to genotoxic stimuli
Berchtold, Craig M; Wu, Zhao-Hui; Huang, Tony T; Miyamoto, Shigeki
2007 Jan;27(2):497-509, Molecular & cellular biology
— id: 69204, year: 2007, vol: 27, page: 497, stat: Journal Article,

A UAF1-containing multisubunit protein complex regulates the Fanconi anemia pathway
Cohn, Martin A; Kowal, Przemyslaw; Yang, Kailin; Haas, Wilhelm; Huang, Tony T; Gygi, Steven P; D'Andrea, Alan D
2007 Dec 14;28(5):786-797, Molecular cell
— id: 130275, year: 2007, vol: 28, page: 786, stat: Journal Article,

FANCI is a second monoubiquitinated member of the Fanconi anemia pathway
Sims, Ashley E; Spiteri, Elizabeth; Sims, Robert J 3rd; Arita, Adriana G; Lach, Francis P; Landers, Thomas; Wurm, Melanie; Freund, Marcel; Neveling, Kornelia; Hanenberg, Helmut; Auerbach, Arleen D; Huang, Tony T
2007 Jun;14(6):564-567, Nature structural & molecular biology
— id: 72707, year: 2007, vol: 14, page: 564, stat: Journal Article,

HAUSP hunting the FOX(O)
Huang, Tony T; D'Andrea, Alan D
2006 Oct;8(10):1043-1045, Nature cell biology
— id: 69205, year: 2006, vol: 8, page: 1043, stat: Journal Article,

Regulation of DNA repair by ubiquitylation
Huang, Tony T; D'Andrea, Alan D
2006 May;7(5):323-334, Nature reviews. Molecular cell biology
— id: 69206, year: 2006, vol: 7, page: 323, stat: Journal Article,

Regulation of monoubiquitinated PCNA by DUB autocleavage
Huang, Tony T; Nijman, Sebastian M B; Mirchandani, Kanchan D; Galardy, Paul J; Cohn, Martin A; Haas, Wilhelm; Gygi, Steven P; Ploegh, Hidde L; Bernards, Rene; D'Andrea, Alan D
2006 Apr;8(4):339-347, Nature cell biology
— id: 69207, year: 2006, vol: 8, page: 339, stat: Journal Article,

The deubiquitinating enzyme USP1 regulates the Fanconi anemia pathway
Nijman, Sebastian M B; Huang, Tony T; Dirac, Annette M G; Brummelkamp, Thijn R; Kerkhoven, Ron M; D'Andrea, Alan D; Bernards, Rene
2005 Feb 4;17(3):331-339, Molecular cell
— id: 69208, year: 2005, vol: 17, page: 331, stat: Journal Article,

Sequential modification of NEMO/IKKgamma by SUMO-1 and ubiquitin mediates NF-kappaB activation by genotoxic stress
Huang, Tony T; Wuerzberger-Davis, Shelly M; Wu, Zhao-Hui; Miyamoto, Shigeki
2003 Nov 26;115(5):565-576, Cell
— id: 69209, year: 2003, vol: 115, page: 565, stat: Journal Article,

The zinc finger domain of NEMO is selectively required for NF-kappa B activation by UV radiation and topoisomerase inhibitors
Huang, Tony T; Feinberg, Shelby L; Suryanarayanan, Sainath; Miyamoto, Shigeki
2002 Aug;22(16):5813-5825, Molecular & cellular biology
— id: 69210, year: 2002, vol: 22, page: 5813, stat: Journal Article,

Postrepression activation of NF-kappaB requires the amino-terminal nuclear export signal specific to IkappaBalpha
Huang, T T; Miyamoto, S
2001 Jul;21(14):4737-4747, Molecular & cellular biology
— id: 130276, year: 2001, vol: 21, page: 4737, stat: Journal Article,

A nuclear export signal in the N-terminal regulatory domain of IkappaBalpha controls cytoplasmic localization of inactive NF-kappaB/IkappaBalpha complexes
Huang, T T; Kudo, N; Yoshida, M; Miyamoto, S
2000 Feb 1;97(3):1014-1019, Proceedings of the National Academy of Sciences of the United States of America
— id: 130279, year: 2000, vol: 97, page: 1014, stat: Journal Article,

NF-kappaB activation by camptothecin. A linkage between nuclear DNA damage and cytoplasmic signaling events
Huang, T T; Wuerzberger-Davis, S M; Seufzer, B J; Shumway, S D; Kurama, T; Boothman, D A; Miyamoto, S
2000 Mar 31;275(13):9501-9509, Journal of biological chemistry
— id: 130278, year: 2000, vol: 275, page: 9501, stat: Journal Article,

Cellular and molecular responses to topoisomerase I poisons. Exploiting synergy for improved radiotherapy
Miyamoto, S; Huang, T T; Wuerzberger-Davis, S; Bornmann, W G; Pink, J J; Tagliarino, C; Kinsella, T J; Boothman, D A
2000 ;922:274-292, Annals of the New York Academy of Sciences
— id: 130277, year: 2000, vol: 922, page: 274, stat: Journal Article,