Brian W. Hainline, M.D.

Neuropathic Pain: Mind-body Considerations
Hainline, Brian
2011 Feb;29(1):19-33, Neurologic clinics
Emerging research in neuroscience is bridging the gap between mind and body. Thought is brain based and influences brain function. The continuum and bidirectionality of mind and body, thought and brain, emotions and physiology forms the basis of understanding neuropathic pain, a neuropsychiatric condition with myriad clinical manifestations
— id: 116218, year: 2011, vol: 29, page: 19, stat: Journal Article,

Chronic pain: physiological, diagnostic, and management considerations
Hainline, Brian
2005 Sep;28(3):713-35, 731, Psychiatric clinics of North America
Neuropathic pain is a neuropsychiatric condition in which pain is initiated or caused by a primary lesion or dysfunction in the nervous system. Understanding the complexity of neuropathic pain becomes the cornerstone for appropriate diagnosis and management. Diagnosis must take into account comorbid conditions. Successful management depends on realistic patient and physician expectations and an individualized, multidisciplinary approach
— id: 58891, year: 2005, vol: 28, page: 713, stat: Journal Article,

Neurological complications of pregnancy
Devinsky, Orrin; Feldmann, Edward; Hainline, Brian
Philadelphia, PA. : Lippincott Williams & Wilkins, c2002,
— id: 736, year: 2002, vol: , page: , stat: ,

Low back pain
Hainline, Brian
2002 ;90(3):9-23, Advances in neurology
— id: 35832, year: 2002, vol: 90, page: 9, stat: Journal Article,

Migraine and other headache conditions
Hainline, Brian
2002 ;90(3):25-40, Advances in neurology
Migraine and other headache conditions are relatively common during pregnancy. Physicians and other primary health care providers should not assume that because a patient presents with headache alone, such symptoms can be taken lightly. Most patients do not develop new-onset headache during pregnancy, and all patients who do develop such a condition must be evaluated thoroughly. Similarly, patients who develop any change in their headache condition must undergo a careful evaluation. Fig. 3.1 is an algorithm to aid in evaluating pregnant patients with headache. Postpartum headaches also must be evaluated and treated appropriately. In most cases of headache during pregnancy and postpartum, the patient is suffering with a benign medical condition. Even so, quality of life is an important consideration in preserving the patient's physical and emotional well-being (102, 103). A stepwise approach to symptomatic treatment should be provided for all patients. A high index of suspicion for nonbenign causes of headache will assist in decreasing morbidity and mortality to the mother and fetus
— id: 35834, year: 2002, vol: 90, page: 25, stat: Journal Article,

Complementary and alternative medicine
Rosman, Steven M; Hainline, Brian
2002 ;90(3):307-316, Advances in neurology
— id: 35833, year: 2002, vol: 90, page: 307, stat: Journal Article,

To the Editor
Hainline B
2001 Jun;2(3):300-302, Epilepsy & behavior
— id: 35831, year: 2001, vol: 2, page: 300, stat: Journal Article,

Growth failure in Prader-Willi syndrome is secondary to growth hormone deficiency
Thacker MJ; Hainline B; St. Dennis-Feezle L; Johnson NB; Pescovitz OH
1998 ;49(5):216-220, Hormone research
Growth failure is a recognized feature of the Prader-Willi syndrome (PWS). Despite evidence that hypothalamic dysfunction accompanies the syndrome, the etiology of this growth failure remains controversial because most patients with PWS are obese. In order to contribute to resolution of this controversy, we performed a retrospective analysis of 16 obese and non-obese PWS children. GH deficiency was diagnosed in 12 of the 16 subjects and occurred independently of weight status. All of the non-obese subjects were GH deficient. Of the 4 GH-sufficient children, 2 were moderately obese and 2 were morbidly obese. One of these children had clinical evidence of GH deficiency including a low IGF-1 level. Only one of the children had evidence of GH deficiency and a normal IGF-1 level, a pattern that could be attributable to obesity. We conclude that most short children with PWS have growth hormone deficiency and that this deficiency probably results from hypothalamic dysfunction
— id: 9078, year: 1998, vol: 49, page: 216, stat: Journal Article,

Low back injury
Hainline B
1995 Jan;14(1):241-265, Clinics in sports medicine
Low back injuries occur commonly in tennis, but the pathophysiologic, biomechanical, and clinical characteristics are not well defined. Tennis players may be at an increased risk of lumbar disc pathology from rotational and hyperextension shearing effects. Treatment of low back injury at present is empiric, but sport-specific lumbar stabilization and unloading of the lumbar disc should be developed. Prospective longitudinal research protocols are needed to study the lumbar spine in tennis players
— id: 9079, year: 1995, vol: 14, page: 241, stat: Journal Article,

Psychogenic basilar migraine: report of four cases
Sanchez-Villasenor F; Devinsky O; Hainline B; Weinreb H; Luciano D; Vazquez B
1995 Jul;45(7):1291-1294, Neurology
We discuss four patients with the clinical diagnosis of basilar migraine and suspected coexisting epilepsy who were referred to our epilepsy center. Their symptoms suggested episodic dysfunction in the distribution of the basilar artery, followed by pulsating headache with nausea. Verbal unresponsiveness and sensory symptoms occurred in all four patients; two also had focal paresis or jerking movements. Diagnostic studies excluded other disorders with similar symptoms. None of the patients improved with antimigraine or antiepileptic drugs. Provocation tests with suggestion elicited typical events in three patients and aura and headache in one patient. There were no EEG or ECG abnormalities during spontaneous or provoked episodes. Two patients improved with psychiatric treatment. Conversion disorder or malingering should be considered in patients whose symptoms of basilar migraine are atypical or refractory to treatment
— id: 56844, year: 1995, vol: 45, page: 1291, stat: Journal Article,

Neurological complications of pregnancy
Devinsky, Orrin; Feldmann, Edward; Hainline, Brian
New York, N.Y : Raven Press, 1994,
— id: 483, year: 1994, vol: , page: , stat: ,

Headache
Hainline B
1994 Aug;12(3):443-460, Neurologic clinics
Headache is very common among women of childbearing age and can be influenced by hormonal fluctuations. When pregnant women develop headache, the cause is usually tension-type headache or migraine, but headache may be a symptom of a more serious neurologic or medical condition. This article discusses the differential diagnosis and management of major causes of headache during pregnancy
— id: 9080, year: 1994, vol: 12, page: 443, stat: Journal Article,

Low-back pain in pregnancy
Hainline B
1994 ;64:65-76, Advances in neurology
— id: 9082, year: 1994, vol: 64, page: 65, stat: Journal Article,

Nerve injuries
Hainline B
1994 Mar;78(2):327-343, Medical clinics of North America
Sports medicine physicians should be able to recognize and manage peripheral nerve injuries in athletes. Most often, the injury is a result of repetitive microtrauma, linking peripheral nerve injury to other musculoskeletal injuries in athletes. As with other musculoskeletal injuries, rest and a modification of the athlete's regimen often lead to clinical improvement. If the physician is uncertain about the diagnosis, if the athlete develops a rapid worsening of symptoms and signs, or if the athlete is refractory to treatment, a physician who specializes in peripheral nerve injuries should be consulted
— id: 9081, year: 1994, vol: 78, page: 327, stat: Journal Article,

Semi-pro football player who suffered a cerebral vascular accident following forced cervical flexion and subsequent spinal manipulation
Hainline B
1992 Sep;24(9):1066-1066, Medicine & science in sports & excercise
— id: 9084, year: 1992, vol: 24, page: 1066, stat: Journal Article,

Ataxia in epidural spinal cord compression [see comments]
Hainline B; Tuszynski MH; Posner JB
1992 Nov;42(11):2193-2195, Neurology
Nine patients presented with ataxia as the primary manifestation of epidural spinal cord compression. Eight had known cancer, the ninth an epidural abscess. Lower-extremity dysmetria, gait ataxia, or both, were the only neurologic signs in five patients. An incorrect initial diagnosis led to delay in treatment and subsequent neurologic deterioration in six patients. Failure to recognize isolated, painless ataxia as the initial manifestation of spinal cord compression and appropriately treat the disorder can result in irreversible spinal cord deterioration
— id: 9083, year: 1992, vol: 42, page: 2193, stat: Journal Article,

Use of the Dementia Rating Scale as a test for neuropsychological dysfunction in HIV-positive i.v. drug abusers
Kovner R; Lazar JW; Lesser M; Perecman E; Kaplan MH; Hainline B; Napolitano B
1992 ;9(2):133-137, Journal of substance abuse treatment
Intravenous drug abusers (IVDAs) represent an increasing proportion of the HIV epidemic. Forty-three IVDA's (22 HIV-negative, 21 HIV-positive) were studied using the Mattis Dementia Rating Scale (DRS). All subjects had used intravenous heroin, but reported that they were drug-free at the time of testing. HIV-positive subjects were predominantly symptomatic and were dichotomized into AIDS and non-AIDS groups. All subjects with abnormal DRS scores were HIV-positive (57% of all HIV-positives). All HIV-negative subjects had normal DRS scores while 43% of the positive group obtained such scores. The DRS reliably identifies neuropsychological impairment, and may be a useful screening tool in this population
— id: 9085, year: 1992, vol: 9, page: 133, stat: Journal Article,

Relation of personality and attentional factors to cognitive deficits in human immunodeficiency virus-infected subjects
Kovner R; Perecman E; Lazar W; Hainline B; Kaplan MH; Lesser M; Beresford R
1989 Mar;46(3):274-277, Archives of neurology
In view of the evidence that patients with human immunodeficiency virus infection experience reactive depression and anxiety, it is important to determine whether these factors might account for some of the cognitive deficiencies observed in this group, as is often the case in psychiatric populations. An extensive battery of cognitive, personality, and attention tests was administered to 26 patients who tested positive for the human immunodeficiency virus. In this group were patients who demonstrated no symptoms, patients who had acquired immunodeficiency syndrome-related complex, and patients who had acquired immunodeficiency syndrome. Pearson Product Moment correlations were computed between scores on the three types of measures. The results of this correlational study suggest that cognitive decline in patients infected with human immunodeficiency virus is independent of mood and attentional changes
— id: 9086, year: 1989, vol: 46, page: 274, stat: Journal Article,