Stefan Feske

Biosketch / Results /

Stefan Feske

Associate Professor, Department of Pathology

Contact Info

Address
522 First Avenue
New York, NY 10016

212/263-9066
stefan.feske@nyumc.org


Research Summary

For more information on research in the Feske lab, please refer to: http://labs.pathology.med.nyu.edu/feske-lab/

Research Interests

My lab's research is focused on signaling pathways in cells of the immune system, particularly store-operated calcium entry (SOCE) and CRAC calcium channel function. We are investigating the mechanisms of CRAC channel activation and how calcium signals affect immune function in the context of infection and autoimmunity.

Store-Operated Ca Entry in Follicular T Cells Controls Humoral Immune Responses and Autoimmunity
Vaeth, Martin; Eckstein, Miriam; Shaw, Patrick J; Kozhaya, Lina; Yang, Jun; Berberich-Siebelt, Friederike; Clancy, Robert; Unutmaz, Derya; Feske, Stefan. Store-Operated Ca Entry in Follicular T Cells Controls Humoral Immune Responses and Autoimmunity. Immunity. 2016 May 31;44(6):1350-1364 (2125342)

A novel mutation in ORAI1 presenting with combined immunodeficiency and residual T-cell function
Chou, Janet; Badran, Yousef R; Yee, Christina S K; Bainter, Wayne; Ohsumi, Toshiro K; Al-Hammadi, Suleiman; Pai, Sung-Yun; Feske, Stefan; Geha, Raif S. A novel mutation in ORAI1 presenting with combined immunodeficiency and residual T-cell function. Journal of allergy & clinical immunology. 2015 Jun 9;136(2):479-82.e1 e1004970 (1626762)

Essential role of Orai1 store-operated calcium channels in lactation
Davis, Felicity M; Janoshazi, Agnes; Janardhan, Kyathanahalli S; Steinckwich, Natacha; D'Agostin, Diane M; Petranka, John G; Desai, Pooja N; Roberts-Thomson, Sarah J; Bird, Gary S; Tucker, Deirdre K; Fenton, Suzanne E; Feske, Stefan; Monteith, Gregory R; Putney, James W Jr. Essential role of Orai1 store-operated calcium channels in lactation. Proceedings of the National Academy of Sciences of the United States of America (PNAS). 2015 Apr 20;112(18):5827-5832 (1543492)

STIM1 controls T cell-mediated immune regulation and inflammation in chronic infection
Desvignes, Ludovic; Weidinger, Carl; Shaw, Patrick; Vaeth, Martin; Ribierre, Theo; Liu, Menghan; Fergus, Tawania; Kozhaya, Lina; McVoy, Lauren; Unutmaz, Derya; Ernst, Joel D; Feske, Stefan. STIM1 controls T cell-mediated immune regulation and inflammation in chronic infection. Journal of clinical investigation. 2015 May 4;125(6):2347-2362 (1569062)

Preserved effector functions of human ORAI1- and STIM1-deficient neutrophils
Elling, Roland; Keller, Baerbel; Weidinger, Carl; Haffner, Monika; Deshmukh, Sachin D; Zee, Isabelle; Speckmann, Carsten; Ehl, Stephan; Schwarz, Klaus; Feske, Stefan; Henneke, Philipp. Preserved effector functions of human ORAI1- and STIM1-deficient neutrophils. Journal of allergy & clinical immunology. 2015 Dec 6;137(5):1587-1591.e7 (1877942)