Gregory David

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Gregory David, Ph.D.

Associate Professor; Co Course Director
Department of Biochemistry and Molecular Pharmacology

Contact Info

550 First Avenue
NYU School of Medicine Floor 4 Room 417
Medical Science Building
New York, NY 10016


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1994-1998 — Inst Pasteur, Paris, Graduate Education

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All data from NYU Health Sciences Library Faculty Bibliography — -


Senescence-associated SIN3B promotes inflammation and pancreatic cancer progression
Rielland, Maite; Cantor, David J; Graveline, Richard; Hajdu, Cristina; Mara, Lisa; Diaz, Beatriz de Diego; Miller, George; David, Gregory
2014 May;124(5):2125-2135, Journal of clinical investigation
— id: 1061672, year: 2014, vol: 124, page: 2125, stat: Journal Article,

Inhibition of androgen receptor and ?-catenin activity in prostate cancer
Lee, E; Madar, A; David, G; Garabedian, MJ; Gupta, RD; Logan, SK
2013 ;110(39):15710-15715, Proceedings of the National Academy of Sciences of the United States of America
— id: 785132, year: 2013, vol: 110, page: 15710, stat: Journal Article,

Inhibition of androgen receptor and beta-catenin activity in prostate cancer
Lee, Eugine; Madar, Aviv; David, Gregory; Garabedian, Michael J; Dasgupta, Ramanuj; Logan, Susan K
2013 Sep;110(39):15710-15715, Proceedings of the National Academy of Sciences of the United States of America
— id: 542762, year: 2013, vol: 110, page: 15710, stat: Journal Article,

Regulation of oncogene-induced cell cycle exit and senescence by chromatin modifiers
David, Gregory
2012 Sep;13(11):992-1000, Cancer biology & therapy
— id: 178052, year: 2012, vol: 13, page: 992, stat: Journal Article,

Mineral dust photochemistry induces nucleation events in the presence of SO2
Dupart, Yoan; King, Stephanie M; Nekat, Bettina; Nowak, Andreas; Wiedensohler, Alfred; Herrmann, Hartmut; David, Gregory; Thomas, Benjamin; Miffre, Alain; Rairoux, Patrick; D'Anna, Barbara; George, Christian
2012 Dec;109(51):20842-20847, Proceedings of the National Academy of Sciences of the United States of America
— id: 463772, year: 2012, vol: 109, page: 20842, stat: Journal Article,

Sequence Requirements for Combinatorial Recognition of Histone H3 by the MRG15 and Pf1 Subunits of the Rpd3S/Sin3S Corepressor Complex
Kumar, Ganesan Senthil; Chang, William; Xie, Tao; Patel, Anand; Zhang, Yongbo; Wang, Gang Greg; David, Gregory; Radhakrishnan, Ishwar
2012 Sep;422(4):519-531, Journal of molecular biology
— id: 177220, year: 2012, vol: 422, page: 519, stat: Journal Article,

Chromatin associated Sin3A is essential for male germ cell lineage in the mouse
Pellegrino, Jessica; Castrillon, Diego H; David, Gregory
2012 Sep;369(2):349-355, Developmental biology (Orlando)
— id: 175783, year: 2012, vol: 369, page: 349, stat: Journal Article,

Structural basis for molecular interactions involving MRG domains: implications in chromatin biology
Xie, Tao; Graveline, Richard; Kumar, Ganesan Senthil; Zhang, Yongbo; Krishnan, Arvind; David, Gregory; Radhakrishnan, Ishwar
2012 Jan;20(1):151-160, Structure
— id: 155901, year: 2012, vol: 20, page: 151, stat: Journal Article,

Dissecting the complex regulation of Mad4 in glioblastoma multiforme cells
Yang, Wensheng; Yang, Xiaolu; David, Gregory; Dorsey, Jay F
2012 Nov;13(13):1339-1348, Cancer biology & therapy
— id: 185862, year: 2012, vol: 13, page: 1339, stat: Journal Article,

The human ankyrin insulator supports production of therapeutic levels of adult hemoglobin following beta-globin gene transfer in hematopoietic cells derived from thalassemic and sickle cell patients
Breda, L; Casu, C; Bianchi, N; Cartegni, L; Yazdanbakhsh, K; Manwani, D; Mohandas, N; Jelinic, P; David, G; Gardner, L B; Kleinert, D A; Prus, E; Fibach, E; Giardina, P; Gambari, R; Rivella, S
2011 18 Nov 2011;118(21):-, Blood
— id: 169672, year: 2011, vol: 118, page: , stat: Journal Article,

A Novel Mammalian Complex Containing Sin3B Mitigates Histone Acetylation and RNA Polymerase II Progression within Transcribed Loci
Jelinic, Petar; Pellegrino, Jessica; David, Gregory
2011 Jan;31(1):54-62, Molecular & cellular biology
— id: 115424, year: 2011, vol: 31, page: 54, stat: Journal Article,

Ras-induced senescence and its physiological relevance in cancer
Dimauro, Teresa; David, Gregory
2010 Dec;10(8):869-876, Current cancer drug targets
— id: 138210, year: 2010, vol: 10, page: 869, stat: Journal Article,

The Mammalian sin3 proteins are required for muscle development and sarcomere specification
van Oevelen, Chris; Bowman, Christopher; Pellegrino, Jessica; Asp, Patrik; Cheng, Jemmie; Parisi, Fabio; Micsinai, Mariann; Kluger, Yuval; Chu, Alphonse; Blais, Alexandre; David, Gregory; Dynlacht, Brian D
2010 Dec;30(24):5686-5697, Molecular & cellular biology
— id: 114827, year: 2010, vol: 30, page: 5686, stat: Journal Article,

Chromatin modifications: The driving force of senescence and aging?
Dimauro, Teresa; David, Gregory
2009 ;1(2):182-190, Aging
— id: 107286, year: 2009, vol: 1, page: 182, stat: Journal Article,

Sin3B expression is required for cellular senescence and is up-regulated upon oncogenic stress
Grandinetti, Kathryn B; Jelinic, Petar; DiMauro, Teresa; Pellegrino, Jessica; Fernandez Rodriguez, Ruben; Finnerty, Patricia M; Ruoff, Rachel; Bardeesy, Nabeel; Logan, Susan K; David, Gregory
2009 Aug 15;69(16):6430-6437, Cancer research
— id: 101640, year: 2009, vol: 69, page: 6430, stat: Journal Article,

Specific requirement of the chromatin modifier mSin3B in cell cycle exit and cellular differentiation
David, Gregory; Grandinetti, Kathryn B; Finnerty, Patricia M; Simpson, Natalie; Chu, Gerald C; Depinho, Ronald A
2008 Mar 18;105(11):4168-4172, Proceedings of the National Academy of Sciences of the United States of America
— id: 78025, year: 2008, vol: 105, page: 4168, stat: Journal Article,

Sin3B: an essential regulator of chromatin modifications at E2F target promoters during cell cycle withdrawal
Grandinetti, Kathryn B; David, Gregory
2008 Jun 1;7(11):1550-1554, Cell cycle
— id: 86646, year: 2008, vol: 7, page: 1550, stat: Journal Article,

The F-box protein Fbl10 is a novel transcriptional repressor of c-Jun
Koyama-Nasu, Ryo; David, Gregory; Tanese, Naoko
2007 Sep;9(9):1074-1080, Nature cell biology
— id: 75366, year: 2007, vol: 9, page: 1074, stat: Journal Article,

Haploinsufficiency of the mSds3 chromatin regulator promotes chromosomal instability and cancer only upon complete neutralization of p53
David, G; Dannenberg, J-H; Simpson, N; Finnerty, P M; Miao, L; Turner, G M; Ding, Z; Carrasco, R; Depinho, R A
2006 Nov;25(56):7354-7360, Oncogene
— id: 464122, year: 2006, vol: 25, page: 7354, stat: Journal Article,

mSin3A corepressor regulates diverse transcriptional networks governing normal and neoplastic growth and survival
Dannenberg, Jan-Hermen; David, Gregory; Zhong, Sheng; van der Torre, Jaco; Wong, Wing H; Depinho, Ronald A
2005 Jul 1;19(13):1581-1595, Genes & development
— id: 63113, year: 2005, vol: 19, page: 1581, stat: Journal Article,

New roles for the mSin3-histone deacetylase co-repressor complex in developm
David, Gregory; Dannenberg, Jan-Hermen; Miao, Lili; Turner, Garth; Yao, Ya
2005 JUN;30:94-94, Cell structure & function
— id: 464142, year: 2005, vol: 30, page: 94, stat: Journal Article,

Cdk5/p35 phosphorylates mSds3 and regulates mSds3-mediated repression of transcription
Li, Zhen; David, Gregory; Hung, Kwok-Wang; DePinho, Ronald A; Fu, Amy K Y; Ip, Nancy Y
2004 Dec 24;279(52):54438-54444, Journal of biological chemistry
— id: 63114, year: 2004, vol: 279, page: 54438, stat: Journal Article,

EBNA3C coactivation with EBNA2 requires a SUMO homology domain
Rosendorff, Adam; Illanes, Diego; David, Gregory; Lin, Jeffrey; Kieff, Elliott; Johannsen, Eric
2004 Jan;78(1):367-377, Journal of virology
— id: 63115, year: 2004, vol: 78, page: 367, stat: Journal Article,

mSin3-associated protein, mSds3, is essential for pericentric heterochromatin formation and chromosome segregation in mammalian cells
David, Gregory; Turner, Garth M; Yao, Yao; Protopopov, Alexei; DePinho, Ronald A
2003 Oct 1;17(19):2396-2405, Genes & development
— id: 63116, year: 2003, vol: 17, page: 2396, stat: Journal Article,

Identification of mammalian Sds3 as an integral component of the Sin3/histone deacetylase corepressor complex
Alland, Leila; David, Gregory; Shen-Li, Hong; Potes, Jason; Muhle, Rebecca; Lee, Hye-Chun; Hou, Harry Jr; Chen, Ken; DePinho, Ronald A
2002 Apr;22(8):2743-2750, Molecular & cellular biology
— id: 63118, year: 2002, vol: 22, page: 2743, stat: Journal Article,

SUMO-1 modification of histone deacetylase 1 (HDAC1) modulates its biological activities
David, Gregory; Neptune, Mychell A; DePinho, Ronald A
2002 Jun 28;277(26):23658-23663, Journal of biological chemistry
— id: 63117, year: 2002, vol: 277, page: 23658, stat: Journal Article,

Myc-enhanced expression of Cul1 promotes ubiquitin-dependent proteolysis and cell cycle progression
O'Hagan, R C; Ohh, M; David, G; de Alboran, I M; Alt, F W; Kaelin, W G Jr; DePinho, R A
2000 Sep 1;14(17):2185-2191, Genes & development
— id: 114150, year: 2000, vol: 14, page: 2185, stat: Journal Article,

Gene-target recognition among members of the myc superfamily and implications for oncogenesis
O'Hagan, R C; Schreiber-Agus, N; Chen, K; David, G; Engelman, J A; Schwab, R; Alland, L; Thomson, C; Ronning, D R; Sacchettini, J C; Meltzer, P; DePinho, R A
2000 Feb;24(2):113-119, Nature genetics
— id: 114151, year: 2000, vol: 24, page: 113, stat: Journal Article,

Characterization of the gene encoding the 100-kDa form of human 2',5' oligoadenylate synthetase
Rebouillat, D; Hovnanian, A; David, G; Hovanessian, A G; Williams, B R
2000 Dec;70(2):232-240, Genomics
— id: 464132, year: 2000, vol: 70, page: 232, stat: Journal Article,

Histone deacetylase associated with mSin3A mediates repression by the acute promyelocytic leukemia-associated PLZF protein
David, G; Alland, L; Hong, S H; Wong, C W; DePinho, R A; Dejean, A
1998 May 14;16(19):2549-2556, Oncogene
— id: 114152, year: 1998, vol: 16, page: 2549, stat: Journal Article,

The acute promyelocytic leukemia PML-RAR alpha protein induces hepatic preneoplastic and neoplastic lesions in transgenic mice
David, G; Terris, B; Marchio, A; Lavau, C; Dejean, A
1997 Apr 3;14(13):1547-1554, Oncogene
— id: 114155, year: 1997, vol: 14, page: 1547, stat: Journal Article,

Molecular cloning of a new interferon-induced PML nuclear body-associated protein
Gongora, C; David, G; Pintard, L; Tissot, C; Hua, T D; Dejean, A; Mechti, N
1997 Aug 1;272(31):19457-19463, Journal of biological chemistry
— id: 114153, year: 1997, vol: 272, page: 19457, stat: Journal Article,

SMRT corepressor interacts with PLZF and with the PML-retinoic acid receptor alpha (RARalpha) and PLZF-RARalpha oncoproteins associated with acute promyelocytic leukemia
Hong, S H; David, G; Wong, C W; Dejean, A; Privalsky, M L
1997 Aug 19;94(17):9028-9033, Proceedings of the National Academy of Sciences of the United States of America
— id: 114154, year: 1997, vol: 94, page: 9028, stat: Journal Article,