Mukundan Gopala Krishnan Attur

Biosketch / Results /

Mukundan Gopala Krishnan Attur, Ph.D.

Assistant Professor;
Departments of Medicine (Medicine) and Hospital for Joint Diseases

Contact Info

Address
301 East 17 Streeet
Rheumatology Floor 16 Room 1612
NYU Hospital for Joint Diseases
New York, NY 10003

212-598-6578
212-548-7604
Mukundan.Attur@nyumc.org

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All data from NYU Health Sciences Library Faculty Bibliography — -

Contact:
http://hsl.med.nyu.edu/faculty-bibliography-search

The coupling of bone and cartilage turnover in osteoarthritis: opportunities for bone antiresorptives and anabolics as potential treatments?
Karsdal, M A; Bay-Jensen, A C; Lories, R J; Abramson, S; Spector, T; Pastoureau, P; Christiansen, C; Attur, M; Henriksen, K; Goldring, S R; Kraus, V
2014 Feb;73(2):336-348, Annals of rheumatic diseases
— id: 781682, year: 2014, vol: 73, page: 336, stat: Journal Article,

Age-dependent ferritin elevations and HFE C282Y mutation as risk factors for symptomatic knee osteoarthritis in males: a longitudinal cohort study
Kennish, Lauren; Attur, Mukundan; Oh, Cheongeun; Krasnokutsky, Svetlana; Samuels, Jonathan; Greenberg, Jeffrey D; Huang, Xi; Abramson, Steven B
2014 Jan;15(1):8-8, BMC musculoskeletal disorders
— id: 723462, year: 2014, vol: 15, page: 8, stat: Journal Article,

F-spondin deficient mice have a high bone mass phenotype
Palmer, Glyn D; Attur, Mukundan G; Yang, Qing; Liu, James; Moon, Paxton; Beier, Frank; Abramson, Steven B
2014 ;9(5):e98388-e98388 e98388, PLoS ONE
— id: 1019052, year: 2014, vol: 9, page: e98388, stat: Journal Article,

TSG-6 activity as a novel biomarker of progression in knee osteoarthritis
Wisniewski, H-G; Colon, E; Liublinska, V; Karia, R J; Stabler, T V; Attur, M; Abramson, S B; Band, P A; Kraus, V B
2014 Feb;22(2):235-241, Osteoarthritis & cartilage
— id: 806742, year: 2014, vol: 22, page: 235, stat: Journal Article,

Interleukin-1 Receptor Antagonist (IL-1Ra) Plasma Levels Predict Radiographic Progression Of Symptomatic Knee Osteoarthritis Over 24 Months
Attur, Mukundan ; Statnikov, Alexander ; Samuels, Jonathan ; Krasnokutsky, Svetlana ; Greenberg, Jeffrey D. ; Li, Zhiguo ; Rybak, Leon ; Aliferis, Constantin F. ; Abramson, Steven B.
2013 OCT;65 10 10(SI):S804-S804, Arthritis & rheumatism
— id: 657592, year: 2013, vol: 65 10 10, page: S804, stat: Journal Article,

Prognostic biomarkers in osteoarthritis
Attur, Mukundan; Krasnokutsky-Samuels, Svetlana; Samuels, Jonathan; Abramson, Steven B
2013 Jan;25(1):136-144, Current opinion in rheumatology
— id: 184992, year: 2013, vol: 25, page: 136, stat: Journal Article,

F-SPONDIN (SPONDIN-1) NULL MICE EXHIBIT INCREASED BONE FORMATION, DECREASED OSTEOCLAST FUNCTION AND ACCELERATED OSTEOARTHRITIS
Attur, M.; Palmer, C.; Liu, J.; Qing, Y.; Rifkin, D.; Bryce, D.; Beier, F.; Abramson, S. B.
2012 APR;20 1 1:S59-S59, Osteoarthritis & cartilage
— id: 166902, year: 2012, vol: 20 1 1, page: S59, stat: Journal Article,

INFLAMMATORY GENOMIC AND PLASMA BIOMARKERS PREDICT PROGRESSION OF SYMPTOMATIC KNEE OA (SKOA)
Attur, M.; Statnikov, A.; Aliferis, C. F.; Li, Z.; Krasnokutsky, S.; Samuels, J.; Greenberg, J. D.; Patel, J.; Oh, C.; Lu, Q. A.; Ramirez, R.; Todd, J.; Abramson, S. B.
2012 APR;20 1 1:S34-S35, Osteoarthritis & cartilage
— id: 166845, year: 2012, vol: 20 1 1, page: S34, stat: Journal Article,

Perturbation of nuclear lamin A causes cell death in chondrocytes
Attur, Mukundan; Ben-Artzi, Ami; Yang, Qing; Al-Mussawir, Hayf E; Worman, Howard J; Palmer, Glyn; Abramson, Steven B
2012 Jun;64(6):1940-1949, Arthritis & rheumatism
— id: 169241, year: 2012, vol: 64, page: 1940, stat: Journal Article,

Activation of diverse eicosanoid pathways in osteoarthritic cartilage: a lipidomic and genomic analysis
Attur, Mukundan; Dave, Mandar; Abramson, Steven B; Amin, Ashok
2012 ;70(2):99-108, Bulletin of the NYU Hospital for Joint Diseases
— id: 177088, year: 2012, vol: 70, page: 99, stat: Journal Article,

Elevated Fecal Secretory Immunoglobulin A, Anti-Cyclic Citrullinated Peptide Antibodies, and Cytokine Levels in Rheumatoid Arthritis Patients
Dalvi, Sam; Scher, Jose U.; Attur, Mukundan; Patel, Jyoti; Abramson, Steven B.
2012 OCT;64(10 S S):S518-S518, Arthritis & rheumatism
— id: 184172, year: 2012, vol: 64, page: S518, stat: Journal Article,

Carotid Arterial Wall Inflammation Is Associated with a Specific Profile of Inflammatory Biomarkers and Anti-Citrullinated Protein Antibodies in Rheumatoid Arthritis Patients
Groenwall, Caroline; Silverman, Gregg; Fayad, Zahi; Mani, Venkatesh; Furer, Victoria; Farkouh, Michael; Jain, Manish; Oh, Cheongeun; Todd, John; Attur, Mukundan; Abramson, Steven B.; Greenberg, Jeffrey D.
2012 OCT;64(10 S S):S539-S540, Arthritis & rheumatism
— id: 184072, year: 2012, vol: 64, page: S539, stat: Journal Article,

Carotid arterial wall inflammation is associated with a specific profile of inflammatory biomarkers and anti-citrullinated protein antibodies in rheumatoid arthritis patients
Gronwall, C; Silverman, G; Fayad, Z; Mani, V; Furer, V; Farkouh, M; Jain, M; Oh, C; Todd, J; Attur, M; Abramson, S B; Greenberg, J D
2012 October 2012;64:S539-S540, Arthritis & rheumatism
— id: 241772, year: 2012, vol: 64, page: S539, stat: Journal Article,

Enhanced COMP catabolism detected in serum of patients with arthritis and animal disease models through a novel capture ELISA
Lai, Y; Yu, XP; Zhang, Y; Tian, Q; Song, H; Mucignat, MT; Perris, R; Samuels, J; Krasnokutsky, S; Attur, M; Greenberg, JD; Abramson, SB; Di, Cesare PE; Liu, C
2012 May;:854-862, Osteoarthritis & cartilage
— id: 169424, year: 2012, vol: , page: 854, stat: Journal Article,

Orphan nuclear receptor NR4A2 induces synoviocyte proliferation, invasion, and matrix metalloproteinase 13 transcription
Mix, Kimberlee S; McMahon, Kevin; McMorrow, Jason P; Walkenhorst, Dana E; Smyth, Aisling M; Petrella, Brenda L; Gogarty, Martina; Fearon, Ursula; Veale, Douglas; Attur, Mukundan G; Abramson, Steven B; Murphy, Evelyn P
2012 Jul;64(7):2126-2136, Arthritis & rheumatism
— id: 172992, year: 2012, vol: 64, page: 2126, stat: Journal Article,

Periodontal disease and the oral microbiota in new-onset rheumatoid arthritis
Scher, Jose U; Ubeda, Carles; Equinda, Michele; Khanin, Raya; Buischi, Yvonne; Viale, Agnes; Lipuma, Lauren; Attur, Mukundan; Pillinger, Michael H; Weissmann, Gerald; Littman, Dan R; Pamer, Eric G; Bretz, Walter A; Abramson, Steven B
2012 May;:3083-3094, Arthritis & rheumatism
— id: 178156, year: 2012, vol: , page: 3083, stat: Journal Article,

Glatiramer acetate (GA), the immunomodulatory drug, inhibits inflammatory mediators and collagen degradation in osteoarthritis (OA) cartilage
Attur, M; Millman, J S; Dave, M N; Al-Mussawir, H E; Patel, J; Palmer, G; Abramson, S B
2011 Sep;19(9):1158-1164, Osteoarthritis & cartilage
— id: 136941, year: 2011, vol: 19, page: 1158, stat: Journal Article,

F-spondin (spondin-1) null mice exhibit increased bone formation
Attur, M; Palmer, G; Liu, J; Qing, Y; Rifkin, D; Beier, F; Abramson, S B
2011 October 2011;63(10):-, Arthritis & rheumatism
— id: 170463, year: 2011, vol: 63, page: , stat: Journal Article,

Increased interleukin-1beta gene expression in peripheral blood leukocytes is associated with increased pain and predicts risk for progression of symptomatic knee osteoarthritis
Attur, Mukundan; Belitskaya-Levy, Ilana; Oh, Cheongeun; Krasnokutsky, Svetlana; Greenberg, Jeffrey; Samuels, Jonathan; Smiles, Stephen; Lee, Sicy; Patel, Jyoti; Al-Mussawir, Hayf; McDaniel, Gary; Kraus, Virginia Byers; Abramson, Steven B
2011 Jul;63(7):1908-1917, Arthritis & rheumatism
— id: 134740, year: 2011, vol: 63, page: 1908, stat: Journal Article,

Elevated Expression of Inflammatory Mediators Cyclooxygenase-2, Its Product Prostaglandin E2 and Interleukin-1 Beta by Peripheral Blood Leukocytes in Symptomatic Knee Osteoarthritis
Attur, Mukundan; Statnikov, Alexander; Aliferis, Constantin F.; Li, Zhiguo; Krasnokutsky, Svetlana; Samuels, Jonathan; Greenberg, Jeffrey D.; Patel, Jyoti; Oh, Cheongeun; Abramson, Steven B.
2011 OCT;63(10):S61-S62, Arthritis & rheumatism
— id: 764062, year: 2011, vol: 63, page: S61, stat: Journal Article,

Large-scale meta-analysis of interleukin-1 beta and interleukin-1 receptor antagonist polymorphisms on risk of radiographic hip and knee osteoarthritis and severity of knee osteoarthritis
Kerkhof, H J M; Doherty, M; Arden, N K; Abramson, S B; Attur, M; Bos, S D; Cooper, C; Dennison, E M; Doherty, S A; Evangelou, E; Hart, D J; Hofman, A; Javaid, K; Kerna, I; Kisand, K; Kloppenburg, M; Krasnokutsky, S; Maciewicz, R A; Meulenbelt, I; Muir, K R; Rivadeneira, F; Samuels, J; Sezgin, M; Slagboom, E; Smith, A J P; Spector, T D; Tamm, A; Tamm, A; Uitterlinden, A G; Wheeler, M; Zhai, G; Zhang, W; van Meurs, J B J; Valdes, A M
2011 Mar;19(3):265-271, Osteoarthritis & cartilage
— id: 133192, year: 2011, vol: 19, page: 265, stat: Journal Article,

Quantitative magnetic resonance imaging evidence of synovial proliferation is associated with radiographic severity of knee osteoarthritis
Krasnokutsky, Svetlana; Belitskaya-Levy, Ilana; Bencardino, Jenny; Samuels, Jonathan; Attur, Mukundan; Regatte, Ravinder; Rosenthal, Pamela; Greenberg, Jeffrey; Schweitzer, Mark; Abramson, Steven B; Rybak, Leon
2011 Oct;63(10):2983-2991, Arthritis & rheumatism
— id: 137878, year: 2011, vol: 63, page: 2983, stat: Journal Article,

Interleukin-1 receptor antagonist (IL-1RN) gene variations predict the severity and progression of knee osteoarthritis
Attur M.; Oh C.; Krasnokutsky S.; Samuels J.; Rybak L.; Bencardino J.; Greenberg J.D.
2010 ;62:707-707, Arthritis & rheumatism
— id: 130940, year: 2010, vol: 62, page: 707, stat: Journal Article,

ASSOCIATION OF INTERLEUKIN-1 RECEPTOR ANTAGONIST (IL-1RN) TTG HAPLOTYPE WITH RADIOGRAPHIC KNEE OA SEVERITY IN META-ANALYSIS
Attur, M.; Kerkhof, H.; Oh, C.; Krasnokutsky, S.; Samuels, J.; Uitterlinden, A. G.; Hofman, A.; Rivadeneira, F.; Valdes, A.; Spector, T. D.; van Meurs, J.; Abramson, S. B.
2010 OCT ;18(12):S172-S172, Osteoarthritis & cartilage
— id: 120556, year: 2010, vol: 18, page: S172, stat: Journal Article,

INTERLEUKIN-1 RECEPTOR ANTAGONIST GENE VARIATIONS PREDICT THE SEVERITY AND PROGRESSION OF KNEE OSTEOARTHRITIS
Attur, M.; Oh, C.; Krasnokutsky, S.; Samuels, J.; Rybak, L.; Bencardino, J.; Kraus, V.; Kornman, K.; Abramson, S. B.
2010 OCT ;18(12):S172-S172, Osteoarthritis & cartilage
— id: 120557, year: 2010, vol: 18, page: S172, stat: Journal Article,

Targeting the synovial tissue for treating osteoarthritis (OA): where is the evidence?
Attur, Mukundan; Samuels, Jonathan; Krasnokutsky, Svetlana; Abramson, Steven B
2010 Feb;24(1):71-79, Bailliere's best practice & research. Clinical rheumatology
— id: 107276, year: 2010, vol: 24, page: 71, stat: Journal Article,

Radiographic severity of knee osteoarthritis is conditional on interleukin 1 receptor antagonist gene variations
Attur, Mukundan; Wang, Hwa-Ying; Kraus, Virginia Byers; Bukowski, Jack F; Aziz, Nazneen; Krasnokutsky, Svetlana; Samuels, Jonathan; Greenberg, Jeffrey; McDaniel, Gary; Abramson, Steven B; Kornman, Kenneth S
2010 May;69(5):856-861, Annals of rheumatic diseases
— id: 109509, year: 2010, vol: 69, page: 856, stat: Journal Article,

Effects of NSAIDs and the Cyclooxygenase-Inhibiting Nitric Oxide Donator (CINOD) NCX 429 on human chondrocytes and cartilage from OA patients
Bolla M.; Viappiani S.; Dave M.; Patel J.; Abramson S.B.; Attur M.
2010 ;62:1477-1477, Arthritis & rheumatism
— id: 130933, year: 2010, vol: 62, page: 1477, stat: Journal Article,

The role of microRNA in rheumatoid arthritis and other autoimmune diseases
Furer, Victoria; Greenberg, Jeffrey D; Attur, Mukundan; Abramson, Steven B; Pillinger, Michael H
2010 Jul;136(1):1-15, Clinical immunology
— id: 110075, year: 2010, vol: 136, page: 1, stat: Journal Article,

LARGE SCALE META-ANALYSIS OF INTERLEUKIN-1 BETA AND INTERLEUKIN-1 RECEPTOR ANTAGONIST POLYMORPHISMS ON RISK OF RADIOGRAPHIC HIP AND KNEE OSTEOARTHRITIS AND SEVERITY OF KNEE OSTEOARTHRITIS
Kerkhof, H. J.; Doherty, M.; Abramson, S. B.; Arden, N. K.; Attur, M.; Bos, S.; Cooper, C.; Doherty, S. A.; Evangelou, E.; Kerna, I.; Kisand, K.; Kloppenburg, M.; Maciewicz, R. A.; Meulenbelt, I.; Sezgin, M.; Slagboom, E.; Smith, A.; Spector, T. D.; Tamm, A.; Tamm, A.; Uitterlinden, A. G.; Wheeler, M.; Zhang, W.; van Meurs, J. B.; Valdes, A. M.
2010 OCT ;18(12):S166-S166, Osteoarthritis & cartilage
— id: 120555, year: 2010, vol: 18, page: S166, stat: Journal Article,

Radiographic severity of knee osteoarthritis predicts quantitative Bone Marrow Lesions on MRI
Krasnokutsky S.; Regatte R.; Bencardino J.; Rybak L.; Belitskaya-Levy I.; Samuels J.; Attur M.
2010 ;62:137-137, Arthritis & rheumatism
— id: 130946, year: 2010, vol: 62, page: 137, stat: Journal Article,

miR-7 and miR-130b are differentially regulated during Mesenchymal Stem Cell commitment
Palmer G.; Danielson L.S.; Attur M.; Abramson S.B.; Hernando E.
2010 ;62:1490-1490, Arthritis & rheumatism
— id: 130943, year: 2010, vol: 62, page: 1490, stat: Journal Article,

MIR-7 AND MIR-130B ARE DIFFERENTIALLY REGULATED DURING MESENCHYMAL STEM CELL COMMITMENT
Palmer, G.; Danielson, L.; Attur, M.; Abramson, S. B.; Hernando, E.
2010 OCT ;18(12):S39-S39, Osteoarthritis & cartilage
— id: 120554, year: 2010, vol: 18, page: S39, stat: Journal Article,

F-spondin regulates chondrocyte terminal differentiation and endochondral bone formation
Palmer, Glyn D; Piton, Alejandro H; Thant, Lwin Mon; Oliveira, Serafim M; D'Angelo, Marina; Attur, Mukundan G; Abramson, Steven B; Teixeira, Cristina C
2010 Oct;28(10):1323-1329, Journal of orthopaedic research
— id: 156193, year: 2010, vol: 28, page: 1323, stat: Journal Article,

Hand osteoarthritis (OA) a predictor of accelerated progression in knee OA?
Samuels J.; Petchprapa C.; Carpenter E.L.; Krasnokutsky S.; Attur M.; Rybak L.; Bencardino J.
2010 ;62:708-708, Arthritis & rheumatism
— id: 130937, year: 2010, vol: 62, page: 708, stat: Journal Article,

Protein kinase C-theta mediates negative feedback on regulatory T cell function
Zanin-Zhorov, Alexandra; Ding, Yi; Kumari, Sudha; Attur, Mukundan; Hippen, Keli L; Brown, Maryanne; Blazar, Bruce R; Abramson, Steven B; Lafaille, Juan J; Dustin, Michael L
2010 Apr 16;328(5976):372-376, Science
— id: 109214, year: 2010, vol: 328, page: 372, stat: Journal Article,

Developments in the scientific understanding of osteoarthritis
Abramson, Steven B; Attur, Mukundan
2009 ;11(3):227-227, Arthritis research & therapy
— id: 101117, year: 2009, vol: 11, page: 227, stat: Journal Article,

Association of genetic polymorphism in inflammatory cytokines with radiographic knee OA severity and generalized Osteoarthritis (GOA)
Attur M.; Samuels J.; Krasnokutsky S.; Kornman K.; Aziz N.; Kraus V.B.; McDaniel G.
2009 ;60:767-767, Arthritis & rheumatism
— id: 130318, year: 2009, vol: 60, page: 767, stat: Journal Article,

F-spondin, a neuroregulatory protein, is up-regulated in osteoarthritis and regulates cartilage metabolism via TGF-beta activation
Attur, Mukundan G; Palmer, Glyn D; Al-Mussawir, Hayf E; Dave, Mandar; Teixeira, Cristina C; Rifkin, Daniel B; Appleton, C Thomas G; Beier, Frank; Abramson, Steven B
2009 Jan;23(1):79-89, FASEB journal
— id: 156956, year: 2009, vol: 23, page: 79, stat: Journal Article,

PGE2 differentially regulates expression of chondrocyte markers during chondrogenesis of human bone marrow derived MSCs
Palmer G.; Al-Mussawir H.; Attur M.; Abramson S.B.
2009 ;60:1309-1309, Arthritis & rheumatism
— id: 130337, year: 2009, vol: 60, page: 1309, stat: Journal Article,

F-spondin, a neuroregulatory protein, is upregulated in human and surgically-induced osteoarthritis: Evidence for regulation of cartilage metabolism via latent tgf-b1 activation
Attur, M; Palmer, G; Al-Mussawir, HE; Rifkin, DB; Teixeira, CC; Appleton, CTG; Beier, F; Abramson, SB
2008 SEP ;58(9):S895-S895, Arthritis & rheumatism
— id: 88578, year: 2008, vol: 58, page: S895, stat: Journal Article,

Prostaglandin E2 exerts catabolic effects in osteoarthritis cartilage: evidence for signaling via the EP4 receptor
Attur, Mukundan; Al-Mussawir, Hayf E; Patel, Jyoti; Kitay, Alison; Dave, Mandar; Palmer, Glyn; Pillinger, Michael H; Abramson, Steven B
2008 Oct 1;181(7):5082-5088, Journal of immunology
— id: 91441, year: 2008, vol: 181, page: 5082, stat: Journal Article,

The progeria-associated protein lamin a is upregulated in osteoarthritis: Evidence for premature chondrocyte senescence
Ben-Artzi, A; Attur, M; Dave, M; Al-Mussawir, H; Palmer, G; Abramson, SB
2008 SEP ;58(9):S874-S874, Arthritis & rheumatism
— id: 88576, year: 2008, vol: 58, page: S874, stat: Journal Article,

The antioxidant resveratrol protects against chondrocyte apoptosis via effects on mitochondrial polarization and ATP production
Dave, Mandar; Attur, Mukundan; Palmer, Glyn; Al-Mussawir, Hayf E; Kennish, Lauren; Patel, Jyoti; Abramson, Steven B
2008 Sep;58(9):2786-2797, Arthritis & rheumatism
— id: 93878, year: 2008, vol: 58, page: 2786, stat: Journal Article,

Synovial but not cartilage volumes on MRI predict radiographic severity of knee Osteoarthritis (OA)
Krasnokutsky, S; Samuels, J; Attur, M; Regatte, R; Belitskaya-Levy, I; Babb, J; Rosenthal, P; Al-Mussawir, H; Abellana, V; Greenberg, J; Schweitzer, M; Abramson, SB
2008 SEP ;58(9):S889-S890, Arthritis & rheumatism
— id: 88577, year: 2008, vol: 58, page: S889, stat: Journal Article,

Annexin-1 mediates TNF-alpha-stimulated matrix metalloproteinase secretion from rheumatoid arthritis synovial fibroblasts
Tagoe, Clement E; Marjanovic, Nada; Park, Jean Y; Chan, Edwin S; Abeles, Aryeh M; Attur, Mukundan; Abramson, Steven B; Pillinger, Michael H
2008 Aug 15;181(4):2813-2820, Journal of immunology
— id: 87806, year: 2008, vol: 181, page: 2813, stat: Journal Article,

Protein isoprenylation regulates secretion of matrix metalloproteinase 1 from rheumatoid synovial fibroblasts: effects of statins and farnesyl and geranylgeranyl transferase inhibitors
Abeles, Aryeh M; Marjanovic, Nada; Park, Jean; Attur, Mukundan; Chan, Edwin S; Al-Mussawir, Hayf E; Dave, Mandar; Fisher, Mark C; Stuchin, Steven A; Abramson, Steven B; Pillinger, Michael H
2007 Sep;56(9):2840-2853, Arthritis & rheumatism
— id: 93879, year: 2007, vol: 56, page: 2840, stat: Journal Article,

A subclass of peripheral blood T cells demonstrates increased CD86 expression in patients with rheumatoid arthritis (RA
Ben-Artzi, A; Tse, DB; Attur, M; Greenberg, JD; Nasir, A; Pillinger, MH; Abramson, SB
2007 DEC ;56(12):4305-4306, Arthritis & rheumatism
— id: 87214, year: 2007, vol: 56, page: 4305, stat: Journal Article,

Transcriptional repression of matrix metalloproteinase gene expression by the orphan nuclear receptor NURR1 in cartilage
Mix, Kimberlee S; Attur, Mukundan G; Al-Mussawir, Hayf; Abramson, Steven B; Brinckerhoff, Constance E; Murphy, Evelyn P
2007 Mar 30;282(13):9492-9504, Journal of biological chemistry
— id: 93880, year: 2007, vol: 282, page: 9492, stat: Journal Article,

Anticancer effects of licofelone (ML-3000) in prostate cancer cells
Narayanan, Narayanan K; Nargi, Dominic; Attur, Mukundan; Abramson, Steven B; Narayanan, Bhagavathi A
2007 Jul-Aug;27(4B):2393-2402, Anticancer research
— id: 73813, year: 2007, vol: 27, page: 2393, stat: Journal Article,

Bone marrow changes (edema and fatty infiltration) on MRI predict radiographic severity of knee OA
Regatte R; Krasnokutsky S; Samuels J; Rosenthal P; Abellana V; Greenberg J; Babb J; Schweitzer M; Attur M; Abramson SB
2007 ;15:C180-C180, Osteoarthritis & cartilage
— id: 86572, year: 2007, vol: 15, page: C180, stat: Journal Article,

Prospects for disease modification in osteoarthritis
Abramson, Steven B; Attur, Mukundan; Yazici, Yusuf
2006 Jun;2(6):304-312, Nature clinical practice. Rheumatology
— id: 67863, year: 2006, vol: 2, page: 304, stat: Journal Article,

NURR1 expression is increased in osteoarthritic cartilage and regulates cytokine and metalloproteinase gene transcription: A downstream action of cyclooxygenase 2-derived PGE2
Attur, M; Al-Mussawir, HE; Pillinger, MH; Mix, K; Tetradis, S; Abramson, SB
2006 SEP ;54(9):S616-S616, Arthritis & rheumatism
— id: 70128, year: 2006, vol: 54, page: S616, stat: Journal Article,

Prostaglandin E2 induces mitochondrial dysfunction in osteoarthritic chondrocytes and exerts catabolic effects aa the EP4 receptor
Attur, M; Dave, M; Patel, J; Al-Mussawir, HE; Pillinger, MH; Abramson, SB
2006 SEP ;54(9):S93-S93, Arthritis & rheumatism
— id: 70104, year: 2006, vol: 54, page: S93, stat: Journal Article,

Classification of osteoarthritis biomarkers: a proposed approach
Bauer, D C; Hunter, D J; Abramson, S B; Attur, M; Corr, M; Felson, D; Heinegard, D; Jordan, J M; Kepler, T B; Lane, N E; Saxne, T; Tyree, B; Kraus, V B
2006 Aug;14(8):723-727, Osteoarthritis & cartilage
— id: 522942, year: 2006, vol: 14, page: 723, stat: Journal Article,

Il-1 promotes mitochondrial dysfunction, increases cytosolic cytochrome C and activates caspases in osteoarthritic chondrocytes
Dave, M; Attur, M; AI-Mussawir, HE; Patel, J; Abramson, SB
2006 SEP ;54(9):S72-S72, Arthritis & rheumatism
— id: 70102, year: 2006, vol: 54, page: S72, stat: Journal Article,

Peripheral blood leukocytes (PBL) gene expression profiles as biomarkers in patients with human knee osteciarthritis (OA)
Krasnokutsky, S; Attur, M; Belitskaya-Levy, I; Patel, J; Al-Mussawir, H; Smiles, S; Lee, S; Kraus, V; Kong, SY; McDaniel, G; Abramson, SB
2006 DEC ;54(12):4103-4103, Arthritis & rheumatism
— id: 70764, year: 2006, vol: 54, page: 4103, stat: Journal Article,

APRIL and BAFF promote increased viability of replicating human B2 cells via mechanism involving cyclooxygenase 2
Mongini, Patricia K A; Inman, John K; Han, Hanna; Fattah, Rasem J; Abramson, Steven B; Attur, Mukundan
2006 Jun 1;176(11):6736-6751, Journal of immunology
— id: 64789, year: 2006, vol: 176, page: 6736, stat: Journal Article,

APRIL and BAFF promote clonal expansion of human B2 cells via a COX-2-dependent mechanism
Mongini, PKA; Inman, J; Abramson, S; Attur, M
2006 APR 1 ;176(4):S190-S190, Journal of immunology
— id: 68844, year: 2006, vol: 176, page: S190, stat: Journal Article,

Early-phase PGE(2) production in IL-1-stimulated chondrocytes: Coordinated nuclear localization of COX-1, heat shock protein 90 (Hsp90) and cytosolic prostaglandin e synthase (cPGES)
Park, JY; Marjanovic, N; Attur, M; Al-Mussawir, H; Dave, M; Abeles, AM; Krasnokutsky, S; Pillinger, MH; Abramson, SB
2006 SEP ;54(9):S90-S91, Arthritis & rheumatism
— id: 70103, year: 2006, vol: 54, page: S90, stat: Journal Article,

Simvastatin and geranyl-geranyl transferase inhibitor exhibit chondroprotective effects
Attur, M; Al-Mussawir, H; Abeles, AM; Pillinger, MH; Abramson, SB
2005 SEP ;52(9):S59-S59, Arthritis & rheumatism
— id: 59270, year: 2005, vol: 52, page: S59, stat: Journal Article,

Prostaglandin E2 exerts catabolic effects in OA cartilage: Evidence for signaling via the EP4 receptor
Attur, M; Dave, M; Patel, J; Pillinger, MH; Abramson, SB
2005 SEP ;52(9):S707-S707, Arthritis & rheumatism
— id: 59298, year: 2005, vol: 52, page: S707, stat: Journal Article,

The inflammatory mediator leukotriene B4 (ltb4) exerts catabolic effects on chondrocyte metabolism
Attur, M; Gomez, PF; Patel, J; Al-Mussawir, H; Pillinger, MH; Abramson, SB
2005 SEP ;52(9):S59-S59, Arthritis & rheumatism
— id: 59269, year: 2005, vol: 52, page: S59, stat: Journal Article,

Oxidative injury in osteoarthritis: Is resveratrol of red wine the answer?
Dave, M; Attur, M; Krasnokutsky, S; Patel, J; Abramson, SB
2005 SEP ;52(9):S499-S499, Arthritis & rheumatism
— id: 59289, year: 2005, vol: 52, page: S499, stat: Journal Article,

Expression and subcellular localization of COX 1 and 2 and their associated terminal synthases, cPGES and mPGES, in Il-1-stimulated chondrocytes
Pillinger, MH; Attur, M; Marjanovic, N; Dave, M; Abeles, AM; Merola, J; Krasnokutsky, S; Abramson, SB
2005 SEP ;52(9):S475-S475, Arthritis & rheumatism
— id: 59288, year: 2005, vol: 52, page: S475, stat: Journal Article,

Salutary effects of statins in vitro on cartilage and bone metabolism
Attur, M; Dave, M; Abramson, SB
2004 SEP ;50(9):S287-S288, Arthritis & rheumatism
— id: 49036, year: 2004, vol: 50, page: S287, stat: Journal Article,

Human osteoarthritis chondrocytes produce leukotriene B4 and lipoxin A4: Counter regulatory impact in cartilage
Attur, M; Dave, M; Serhan, C; Abramson, SB
2004 SEP ;50(9):S282-S282, Arthritis & rheumatism
— id: 49035, year: 2004, vol: 50, page: S282, stat: Journal Article,

A family of novel phospholipase A2 enzymes are expressed in synovial tissue and differentially regulated by proinflammatory cytokines in rheumatoid synovial fibroblasts
Bingham, CO; Reddy, SM; Al-Mussawir, H; Attur, M; Abramson, SB
2004 SEP ;50(9):S327-S327, Arthritis & rheumatism
— id: 49040, year: 2004, vol: 50, page: S327, stat: Journal Article,

Resveratrol exerts salutary effects on cartilage metabolism: A French paradox for osteoarthritis?
Dave, MN; Attur, MG; Patel, JN; Abramson, SB
2004 MAR 15 ;12(11):S50-S50, Osteoarthritis & cartilage
— id: 50139, year: 2004, vol: 12, page: S50, stat: Journal Article,

Paracrine pathways of cartilage destruction in osteoarthritis
Abramson, S; Attur, M; Dave, M; Leung, M; Patel, J; Gomez, P; Amin, A
2003 FEB ;5(1):S1-S1, Arthritis research & therapy
— id: 46848, year: 2003, vol: 5, page: S1, stat: Journal Article,

Gene mining and functional genomics in human osteoarthritis
Attur, MG; Dave, MN; Amin, AR
2003 ;4(2):109-121, Current genomics
— id: 564072, year: 2003, vol: 4, page: 109, stat: Journal Article,

The resolution of inflammation: Prostaglandin E dissociates nuclear trafficking of individual NF-kB subunits (p65, p50) in stimulated rheumatoid synoviocytes
Gomez, PF; Pillinger, M; Clancy, R; Attur, M; Amin, A; Al-mussawir, H; Apsel, B; Bingham, CO; Abramson, SB
2003 SEP ;48(9):S253-S253, Arthritis & rheumatism
— id: 55434, year: 2003, vol: 48, page: S253, stat: Journal Article,

Differential expression of novel secretory phospholipase A2 enzymes in osteoarthritic and normal human chondrocytes
Bingham, CO; Reddy, S; Attur, M; Amin, A; Abramson, SB
2002 SEP ;46(9):S220-S221, Arthritis & rheumatism
— id: 55552, year: 2002, vol: 46, page: S220, stat: Journal Article,

Model protocol to study pharmacogenomics in inflammatory diseases: Human rheumatoid arthritis
Attur, M; Bingham, CO; Dave, M; Abramson, SB; Amin, AR
2000 JAN ;49(1):29-33, Drug development research
— id: 54733, year: 2000, vol: 49, page: 29, stat: Journal Article,

Functional genomic analysis in arthritis-affected cartilage: Yin-yang regulation of inflammatory mediators by a5bl and avb3
Attur, MG; Dave, MN; Clancy, RM; Patel, IR; Abramson, SB; Amin, AR
2000 APR 20 ;14(6):A1152-A1152, FASEB journal
— id: 54645, year: 2000, vol: 14, page: A1152, stat: Journal Article,

Gene discovery and functional genomics in human osteoarthritis: Upregulation of osteopontin in human-osteoarthritis affected cartilage and regulation of of nitric oxide and prostaglandin E2
Attur, MG; Dave, MN; Stuchin, SA; Kowalski, AS; Lopez, CA; Zhang, J; Abramson, SB; Denhardt, DT; Amin, AR
2000 APR 20 ;14(6):A1152-A1152, FASEB journal
— id: 54644, year: 2000, vol: 14, page: A1152, stat: Journal Article,

A novel mechanism of action of chemically modified tetracyclines (CMTS): inhibition of COX-2 mediated PGE2 production
Attur, MG; Patel, RN; Dave, MN; Patel, IV; Abramson, SB; Amin, AR
2000 APR 20 ;14(6):A1078-A1078, FASEB journal
— id: 54640, year: 2000, vol: 14, page: A1078, stat: Journal Article,

Tetracycline upregulates COX-2 expression and PGE2 production independent of its effect on nitric oxide
Attur, MG; Patel, RN; Patel, PD; Abramson, SB; Amin, AR
2000 APR 20 ;14(6):A1129-A1129, FASEB journal
— id: 54642, year: 2000, vol: 14, page: A1129, stat: Journal Article,

Regulation of cytosolic COX-2 and prostaglandin E2 production by nitric oxide in activated murine macrophages
Patel, RN; Attur, MG; Dave, MN; Abramson, SB; Amin, AR
2000 APR 20 ;14(6):A1129-A1129, FASEB journal
— id: 54643, year: 2000, vol: 14, page: A1129, stat: Journal Article,

Localization and regulation of COX-2 by nitric oxide in activated murine macrophages
Amin, A; Attur, M; Dave, M; Abramson, S
1998 SEP ;41(9):S143-S143, Arthritis & rheumatism
— id: 53739, year: 1998, vol: 41, page: S143, stat: Journal Article,

Autocrine production of IL-1-beta by human osteoarthritis-affected cartilage and differential regulation of endogenous nitric oxide IL-6, prostaglandin E-2 and IL-8
Amin, AR; Attur, MG; Patel, IR; Patel, RN; Abramson, SB
1998 MAR ;46(3):226A-226A, Journal of investigative medicine
— id: 53498, year: 1998, vol: 46, page: 226A, stat: Journal Article,

Inflammatory mediators (nitric oxide PGE(2)) spontaneously produced by osteoarthritis-affected cartilage regulate stromelysin (MMP-3) production
Amin, AR; Barail, V; Attur, M; Patel, R; Abramson, SB
1998 MAR ;46(3):226A-226A, Journal of investigative medicine
— id: 53497, year: 1998, vol: 46, page: 226A, stat: Journal Article,

TNF-alpha convertase (TACE) from human arthritis-affected cartilage isolation of cDNA by differential display, expression of the active enzyme and regulation of TNF-alpha
Amin, AR; Patel, IR; Attur, MG; Patel, R; Stuchin, SA; Abagyan, R; Abramson, SB
1998 MAR ;46(3):226A-226A, Journal of investigative medicine
— id: 53499, year: 1998, vol: 46, page: 226A, stat: Journal Article,

Tetracyclines upregulate COX-2 expression and PGE(2) production independently from the inhibition of nitric oxide
Amin, AR; Patel, RN; Attur, MG; Patel, PD; Abramson, SB
1998 MAR ;46(3):227A-227A, Journal of investigative medicine
— id: 53500, year: 1998, vol: 46, page: 227A, stat: Journal Article,

Tetracyclines upregulate COX-2 expression and PGE(2) production independently from the inhibition of nitric oxide
Arnin, AR; Patel, RN; Attur, MG; Patel, PD; Abramson, SB
1998 SEP ;41(9):S342-S342, Arthritis & rheumatism
— id: 53749, year: 1998, vol: 41, page: S342, stat: Journal Article,

Autocrine production of IL-1 beta by human osteoarthritis-affected cartilage and differential regulation of endogenous nitric oxide IL-6, prostaglandin E-2 and IL-8
Amin, AK; Attur, MG; Patel, IR; Patel, RN; Thakker, GD; Abramson, SB
1997 SEP ;40(9):902-902, Arthritis & rheumatism
— id: 53194, year: 1997, vol: 40, page: 902, stat: Journal Article,

Inflammatory mediators (nitric oxide, PGE(2)) spontaneously produced by osteoarthritis-affected cartilage regulate stromelysin (MMP-3) production
Amin, AR; Baraji, V; Attur, M; Patel, R; Abramson, SB
1997 SEP ;40(9):904-904, Arthritis & rheumatism
— id: 53195, year: 1997, vol: 40, page: 904, stat: Journal Article,

A novel snake venom-like protease (SVP) from human arthritis-affected cartilage has properties of TNF-alpha convertase regulation in arthritis-affected cartilage
Amin, AR; Patel, IR; Attur, M; Patel, R; Thakker, G; Solomon, K; Abagyan, R; Abramson, SB
1997 SEP ;40(9):285-285, Arthritis & rheumatism
— id: 53181, year: 1997, vol: 40, page: 285, stat: Journal Article,

Post-transcriptional regulation of inducible nitric oxide synthase mRNA in murine macrophages by doxycycline and chemically modified tetracyclines
Amin, AR; Patel, RN; Thakker, GD; Attur, MG; Lowenstein, CJ; Patel, IR; Abramson, SB
1997 SEP ;40(9):398-398, Arthritis & rheumatism
— id: 53184, year: 1997, vol: 40, page: 398, stat: Journal Article,

Cloning and expression of a functional, dimeric, multi-cofactor-requiring murine macrophage inducible nitric oxide synthase in bacteria-to-bacmid transposition-baculovirus system
Patel, IR; Vyas, P; Attur, M; Thakker, G; Abramson, SB; Amin, AR
1997 ;2(2):161-166, Transgenics : biological analysis through DNA transfer
— id: 564772, year: 1997, vol: 2, page: 161, stat: Journal Article,

Osteoarthritis-affected cartilage spontaneously produces COX-2-derived prostaglandin E(2): Regulation by nitric oxide synthase
Amin, AR; Attur, M; Patel, RN; Thakker, GD; Marshall, PJ; Rediske, J; Stuchin, SA; Abramson, SB
1996 SEP ;39(9):1466-1466, Arthritis & rheumatism
— id: 52788, year: 1996, vol: 39, page: 1466, stat: Journal Article,

Nonsteroidal antiinflammatory drugs inhibit the activity of COX-2 and nitric oxide synthase expressed in osteoarthritis-affected cartilage
Amin, AR; Attur, M; Vyas, P; DiCesare, PE; Patel, P; Patel, RN; Steiner, G; Abramson, SB
1996 SEP ;39(9):326-326, Arthritis & rheumatism
— id: 52778, year: 1996, vol: 39, page: 326, stat: Journal Article,

Regulation of osteoarthritis-affected nitric oxide synthase (OA-NOS) by anti-inflammatory drugs
Amin, AR; Attur, M; Vyas, P; DiCesare, PE; Patel, P; Steiner, G; Abramson, SB
1996 MAR ;44(3):A221-A221, Journal of investigative medicine
— id: 52941, year: 1996, vol: 44, page: A221, stat: Journal Article,

Human neutrophils express mRNA for inducible nitric oxide synthase and exhibit intracellular nitric oxide-dependent autacoid functions upon activation, but lack detectable translated product and nitric oxide synthase enzyme activity
Amin, AR; Attur, M; Vyas, P; LeszczynskaPiziak, J; Levartovsky, D; Rediske, J; Clancy, RM; Vora, KA; Abramson, SB
1996 MAR ;44(3):A267-A267, Journal of investigative medicine
— id: 52957, year: 1996, vol: 44, page: A267, stat: Journal Article,

A novel mechanism of action of tetracyclines: Inhibitory effects on nitric oxide synthase activity in osteoarthritis
Amin, AR; Attur, MG; Thakker, DG; Patel, PD; Vyas, PR; Patel, RN; Patel, IR; Abramson, SB
1996 SEP ;39(9):1103-1103, Arthritis & rheumatism
— id: 52783, year: 1996, vol: 39, page: 1103, stat: Journal Article,

Prostaglandin E; PGEY is an inflammatory component in osteoarthrrns-affected cartilage: The Yin-Yang regulation of nitric oxide synthase and cyclooxygenase-2
Amin, AR; Marshall, PJ; Attur, M; Vyas, P; Dicesare, PE; Stucbin, SA; Rediske, J; Abramson, SB
1996 ;44(3):-, Journal of investigative medicine
— id: 564802, year: 1996, vol: 44, page: , stat: Journal Article,

Prostaglandin E(2) (PGE(2)) is an inflammatory component in osteoarthritis-affected cartilage: The yin-yang regulation of nitric oxide synthase and cyclooxygenase-2
Amin, AR; Marshall, PJ; Attur, M; Vyas, P; DiCesare, PE; Stuchin, SA; Rediske, J; Abramson, SB
1996 MAR ;44(3):A292-A292, Journal of investigative medicine
— id: 52962, year: 1996, vol: 44, page: A292, stat: Journal Article,

Nitric oxide produced by cartilage-specific nitric oxide synthase is a common mediator of cartilage degradation in both rheumatoid arthritis and osteoarthritis
Amin, AR; Patel, P; Vyas, P; DiCesare, PE; Attur, M; Abramson, SB
1996 MAR ;44(3):A236-A236, Journal of investigative medicine
— id: 52948, year: 1996, vol: 44, page: A236, stat: Journal Article,

Differential effect of the immunosuppressive drugs cyclosporin, rapamycin and FK506 on inducible nitric oxide synthase and cyclooxygenase-2 expression and function
Attur, M; Vyas, P; Levartovsky, D; Thakker, G; Patel, P; Assef, F; Naqvi, S; Raza, R; Abramson, SB; Amin, AR
1996 MAR ;44(3):A240-A240, Journal of investigative medicine
— id: 52954, year: 1996, vol: 44, page: A240, stat: Journal Article,

Cloning and expression of a functional, dimeric, multi-cofactor-requiring inducible nitric oxide synthase in a novel bacteria-to-bacmid transposition-baculovirus system
Patel, IR; Vyas, P; Attur, M; Abramson, SB; Amin, AR
1996 MAR ;44(3):A205-A205, Journal of investigative medicine
— id: 52937, year: 1996, vol: 44, page: A205, stat: Journal Article,

HUMAN OSTEOARTHRITIS-AFFECTED CHONDROCYTES SPONTANEOUSLY RELEASE NITRIC-OXIDE BY AN INDUCIBLE NEURONAL NITRIC-OXIDE SYNTHASE (OA-NOS) - A NEW TARGET FOR PHARMACOLOGICAL INTERVENTION
AMIN, AR; DICESARE, PE; VYAS, P; ATTUR, M; TZENG, E; BILLIAR, TR; STUCHIN, SA; ABRAMSON, SB
1995 SEP ;38(9):63-63, Arthritis & rheumatism
— id: 86685, year: 1995, vol: 38, page: 63, stat: Journal Article,

PROSTAGLANDIN E(2) (PGE(2)) IS AND INFLAMMATORY COMPONENT IN OSTEOARTHRITIS-AFFECTED CARTILAGE - THE YIN-YANG REGULATION OF NITRIC-OXIDE SYNTHASE AND CYCLOOXYGENASE-2
AMIN, AR; MARSHALL, PJ; ATTUR, M; VYAS, P; REDISKE, J; ABRAMSON, SB
1995 SEP ;38(9):64-64, Arthritis & rheumatism
— id: 86686, year: 1995, vol: 38, page: 64, stat: Journal Article,

A NOVEL MECHANISM OF ACTION FOR NONSTEROIDAL ANTIINFLAMMATORY DRUGS - EFFECTS ON INDUCIBLE NITRIC-OXIDE SYNTHASE
AMIN, AR; VYAS, P; ATTUR, M; LESZCZYNSKAPIZIAK, J; PATEL, IR; WEISSMANN, G; ABRAMSON, SB
1995 SEP ;38(9):1144-1144, Arthritis & rheumatism
— id: 86699, year: 1995, vol: 38, page: 1144, stat: Journal Article,

DIFFERENTIAL REGULATION OF INDUCIBLE NITRIC-OXIDE SYNTHASE BY IMMUNOPHILINS IN MURINE MACROPHAGES
ATTUR, M; VYAS, P; LEVARTOVSKY, D; THAKKER, G; PATEL, P; ASSEF, F; NAQVI, S; RAZA, R; ABRAMSON, SB; AMIN, AR
1995 SEP ;38(9):725-725, Arthritis & rheumatism
— id: 86696, year: 1995, vol: 38, page: 725, stat: Journal Article,