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Paolo Mita, PhD

Institute for Systems Genetics

Research Assistant Professor, Department of Biochemistry and Molecular Pharmacology

Positions

Research Assistant Professor, Department of Biochemistry and Molecular Pharmacology at NYU Grossman School of Medicine

Graduate Education

PhD from New York University

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LINE-1 expression in cancer correlates with p53 mutation, copy number alteration, and S phase checkpoint

McKerrow, Wilson; Wang, Xuya; Mendez-Dorantes, Carlos; Mita, Paolo; Cao, Song; Grivainis, Mark; Ding, Li; LaCava, John; Burns, Kathleen H; Boeke, Jef D; Fenyö, David

Proceedings of the National Academy of Sciences of the United States of America (PNAS). 2022 Feb 22; 119(8):

Unbiased proteomic mapping of the LINE-1 promoter using CRISPR Cas9

Briggs, Erica M; Mita, Paolo; Sun, Xiaoji; Ha, Susan; Vasilyev, Nikita; Leopold, Zev R; Nudler, Evgeny; Boeke, Jef D; Logan, Susan K

Mobile DNA. 2021 Aug 23; 12(1):21

The role of retrotransposable elements in ageing and age-associated diseases

Gorbunova, Vera; Seluanov, Andrei; Mita, Paolo; McKerrow, Wilson; Fenyö, David; Boeke, Jef D; Linker, Sara B; Gage, Fred H; Kreiling, Jill A; Petrashen, Anna P; Woodham, Trenton A; Taylor, Jackson R; Helfand, Stephen L; Sedivy, John M

Nature. 2021 08; 596(7870):43-53

RIP-seq reveals LINE-1 ORF1p association with p-body enriched mRNAs

Briggs, Erica M; McKerrow, Wilson; Mita, Paolo; Boeke, Jef D; Logan, Susan K; Fenyö, David

Mobile DNA. 2021 Feb 09; 12(1):5

SHP2 inhibition diminishes KRASG12C cycling and promotes tumor microenvironment remodeling

Fedele, Carmine; Li, Shuai; Teng, Kai Wen; Foster, Connor J R; Peng, David; Ran, Hao; Mita, Paolo; Geer, Mitchell J; Hattori, Takamitsu; Koide, Akiko; Wang, Yubao; Tang, Kwan Ho; Leinwand, Joshua; Wang, Wei; Diskin, Brian; Deng, Jiehui; Chen, Ting; Dolgalev, Igor; Ozerdem, Ugur; Miller, George; Koide, Shohei; Wong, Kwok-Kin; Neel, Benjamin G

Journal of experimental medicine. 2021 Jan 04; 218(1):

BRCA1 and S phase DNA repair pathways restrict LINE-1 retrotransposition in human cells

Mita, Paolo; Sun, Xiaoji; Fenyö, David; Kahler, David J; Li, Donghui; Agmon, Neta; Wudzinska, Aleksandra; Keegan, Sarah; Bader, Joel S; Yun, Chi; Boeke, Jef D

Nature structural & molecular biology. 2020 Feb; 27(2):179-191

Phylogenetic debugging of a complete human biosynthetic pathway transplanted into yeast

Agmon, Neta; Temple, Jasmine; Tang, Zuojian; Schraink, Tobias; Baron, Maayan; Chen, Jun; Mita, Paolo; Martin, James A; Tu, Benjamin P; Yanai, Itai; Fenyö, David; Boeke, Jef D

Nucleic acids research. 2020 Jan 10; 48(1):486-499

Comprehensive Scanning Mutagenesis of Human Retrotransposon LINE-1 Identifies Motifs Essential for Function

Adney, Emily M; Ochmann, Matthias T; Sil, Srinjoy; Truong, David M; Mita, Paolo; Wang, Xuya; Kahler, David J; Fenyö, David; Holt, Liam J; Boeke, Jef D

Genetics. 2019 Dec; 213(4):1401-1414

See All Publications (27)