Jordan Weiss

Jordan Weiss, PhD

Assistant Professor, Department of Medicine

Keywords
aging, causal inference, dementia, electronic health records, machine learning, multistate modeling, target trial emulation
Summary
I am an assistant professor in the Division of Precision Medicine and Optimal Aging Institute. I do research to understand why some people stay healthy as they age while others do not.    My work aims to solve for the gap between healthspan (the length of time an individual maintains good health) and lifespan (the total length of time an individual lives) by identifying how and for whom key exposures over the life course shape trajectories of health and well-being. I design observational studies that leverage causal inference and AI-based methods, combined with large cohort studies and healthcare records, to emulate hypothetical randomized trials. These studies inform individualized prediction and treatment strategies to optimize health and aging processes.

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Positions

Assistant Professor, Department of Medicine at NYU Grossman School of Medicine

Graduate Education

PhD from University of Pennsylvania

Postdoctoral Training

University of California, Berkeley, Department of Demography

Key research priorities in methodological approaches for measuring the exposome and studying its role in the development of dementia

Nichols, Emma; Keller, Kayleigh P; Chang, Howard; Chiang, Yao-Yi; Gross, Alden L; Hayes-Larson, Eleanor; Claus Henn, Birgit; Kezios, Katrina L; Meijer, Erik; Shih, Regina A; Szpiro, Adam A; Weiss, Jordan; Weuve, Jennifer; Adar, Sara D; Lee, Jinkook

Alzheimer's & dementia : the journal of the Alzheimer's Association. 2025 Nov; 21(11):e70928

Transforming Mortality Prediction: A Transformer-based Mortality Prediction Model

Weiss, Jordan; Azhir, Alaleh; Ram, Nilam; Rehkopf, David H

Journals of gerontology. Series B. Psychological sciences & social sciences. 2025 Jun 10; 80(7):

Cardiovascular disease, bone fracture, and all-cause mortality risks among postmenopausal women by arthritis and veteran status: A multistate Markov transition analysis

Beydoun, Hind A; Beydoun, May A; Weiss, Jordan; Brunner, Robert; Mishra, Nishant K; Ding, Ming; Wactawski-Wende, Jean; Gradidge, Philippe Jean-Luc; Liu, Simin; Tsai, Jack

GeroScience. 2025 Jun; 47(3):4169-4186

Polypharmacy and its association with dementia, Parkinson's disease, and mortality risk in UK adults: a multistate modeling approach

Weiss, Jordan; Beydoun, May A; Georgescu, Michael F; Maldonado, Ana I; Beydoun, Hind A; Noren Hooten, Nicole; Tsai, Jack; Song, Minkyo; Nieva, Allen; Evans, Michele K; Zonderman, Alan B

GeroScience. 2025 Jun; 47(3):4349-4367

Socioeconomic area deprivation and its relationship with dementia, Parkinson's Disease and all-cause mortality among UK older adults: a multistate modeling approach

Beydoun, May A; Georgescu, Michael F; Weiss, Jordan; Noren Hooten, Nicole; Beydoun, Hind A; Tsai, Jack; Maino Vieytes, Christian A; Evans, Michele K; Zonderman, Alan B

Social science & medicine. 2025 May 07; 379:118137

Cardiovascular health and its association with dementia, Parkinson's Disease, and mortality among UK older adults

Georgescu, Michael F; Beydoun, May A; Weiss, Jordan; Kubchandani, Jagdish; Banerjee, Sri; Gamaldo, Alyssa A; Evans, Michele K; Zonderman, Alan B

Brain, behavior, & immunity - health. 2025 May; 45:100986

Lifetime risk and projected burden of dementia

Fang, Michael; Hu, Jiaqi; Weiss, Jordan; Knopman, David S; Albert, Marilyn; Windham, B Gwen; Walker, Keenan A; Sharrett, A Richey; Gottesman, Rebecca F; Lutsey, Pamela L; Mosley, Thomas; Selvin, Elizabeth; Coresh, Josef

Nature medicine. 2025 Mar; 31(3):772-776

Mediating and moderating effects of plasma proteomic biomarkers on the association between poor oral health problems and brain white matter microstructural integrity: the UK Biobank study

Beydoun, May A; Beydoun, Hind A; Hu, Yi-Han; Li, Zhiguang; Georgescu, Michael F; Noren Hooten, Nicole; Bouhrara, Mustapha; Weiss, Jordan; Launer, Lenore J; Evans, Michele K; Zonderman, Alan B

Molecular psychiatry. 2025 Feb; 30(2):388-401

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