G16.2000 Scientific Integrity and the Responsible Conduct of Research
A non-credit course entitled “Scientific Integrity and the Responsible Conduct of Research” is, as mandated by the NIH, required for all first year Ph.D. and M.D./Ph.D. students, post-doctoral trainees, and clinical research fellows at NYUSOM. It is highly recommended for Honors Program students. Dr. Joel Oppenheim and Ms. Debra Stalk coordinate the course. Assisted by a number of faculty volunteers, they are responsible for inviting guest lecturers. The course meets weekly during the Spring semester for approximately 1 1/2 hours per week. Written materials including bibliographies and other resources related to the topic are given out each week. To evaluate the trainees’ comprehension and retention of information presented during the course, a written examination must be passed. Attendance is closely monitored throughout the course. Anyone with two or more absences and/or a failing grade on the exam will be required to repeat the course.
Non-credit
Course Directors:
Joel Oppenheim (212) 263-8001
oppenj01@popmail.med.nyu.edu
Debra Stalk (212) 263-3520
debra.stalk@med.nyu.edu
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G16.2002 Foundations of Cell and Molecular Biology II
Foundations II provides a broad overview of cell biology, signal transduction, and basic genetic mechanisms in three modules. The Cell Biology module covers protein transport, endocytosis, molecular motors, cell-cell interaction and cell adhesion. The Signal Transduction module will include G-proteins, hormonal signaling, concepts in receptor tyrosine kinase signaling, and the cell cycle. The final segment provides an introduction to the genetics of bacterial and phages, yeast, drosophila, mice, and humans. Genetic approaches to whole genome analysis will also be emphasized. The reading of primary research articles is heavily stressed. Lectures will generally be held on Tuesdays and Thursdays in MSB 393 from 9:00 to 10:30 A.M. The discussion sessions, held on Friday, will be in two sections (9:00-10:30 A.M., and 10:30-12:00 noon) in the west wing of the Biochemistry Library (MSB 391). Sections will be decided during the first week of class. The course has a total of three exams that are a mixture of in-class and take-home exams. Attendance and participation in discussion sessions will account for a portion of the final grade.
6 credits
Course Director: James Borowiec (212) 263-8453
borowj01@popmail.med.nyu.edu
Syllabus
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G16.2006 Introduction to Molecular & Developmental Neuroscience
Lectures and discussions will focus on the cellular and molecular properties of individual neurons. Emphasis will be placed on the molecular mechanisms that underlie neuronal polarity, synaptic transmission, impulse propagation, axon transport, neurotransmitter synthesis, release and reuptake/degradation, pre- and post-synaptic organization and myelination, as well as the developmental mechanisms responsible for neurogenesis and patterning, cell specification, axon pathfinding, target selection, forming and eliminating synapses, gliogenesis, cell survival, activity-dependent regulation of synaptic function, and regeneration. Graduate students enrolling in this course should have a background in neuroscience and/or molecular biology.
6 credits
Course directors:
Gord Fishell (212) 263-7691
fishell@saturn.med.nyu.edu
Steve Burden (212) 263-7341
burden@saturn.med.nyu.edu
Jim Salzer (212) 263-0758
jim.salzer@med.nyu.edu
Revised Syllabus
Syllabus
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G16.2104 Tutorial in Advanced Cell Biology
This tutorial is required of advanced students in the cellular and molecular biology program. Students will be paired with CMB faculty to study a varied number of topics.
1.5 credits
Course Director: Daniel Rifkin (212) 263-5234
rifkid01@popmail.med.nyu.edu

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G16. 2210 Molecular Virology
This course is an introduction to the molecular biology and pathogenesis of animal viruses. Twenty lectures cover fundamental aspects of the viral lifecycle (viral entry into cells, replication, transformation, control of translation) host response (innate and acquired immune response), and explore the biology of a number of medically important RNA and DNA viruses including some emerging pathogens. Selected readings assigned by the lecturers will be discussed in separate sections. There will be one in class examination at the conclusion of the course.
4 credits
Course Direcctor: Ian Mohr (212) 263-0415
mohri01@popmail.med.nyu.edu
Syllabus
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G16.2306 Introduction to Immunology
This course is under construction. Details to be provided shortly. Key points to note: this course is offered every spring in odd-numbered years and is required of all graduate students in the Molecular Oncology and Immunology training program.
4 credits
Course Director:
Michael Dustin (212) 263-3207
dustin@saturn.med.nyu.edu
Updated Syllabus
Syllabus
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G16.2404 Molecular Signaling and Drug Development
This course is divided into two parts. The first covers the basics of drug-receptor interactions, and modern approaches to the drug design and development process (virtual library screening, rational drug design, and combinatorial chemistry, etc.). The second part will explore novel possibilities for future drug development as related to specific medical problems, such as HIV, diseases of protein folding, angiogenesis inhibitors, inflammation, and stem cells. A subset of lectures are given by invited speakers from pharmaceutical or biotechnology companies. Each lecture is followed by a student presentation of a research paper and group discussion. At the end of the course, students write a paper outlining and testing a new idea for pharmacological intervention.
4 credits
Course Director: Jan Sap (212) 263-7120
sapj01@med.nyu.edu
Updated Syllabus
Syllabus
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G16.2604 Bioinformatics
This is a practical course in Bioinformatics which will emphasize how to use the computer as a tool for biomedical research. Prerequisites include a thorough understanding of theoretical and practical aspects of molecular biology, and some University level mathematics and statistics, but no prior knowledge of computer programming or computer hardware is necessary.
Course Begins Feb. 1st
4 credits
Course Director: Stuart Brown (212) 263-7689
browns02@popmail.med.nyu.edu
http://www.med.nyu.edu/rcr/rcr/course/syllabus.html
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G16.2609 Developmental Genetics II
This course is a continuation of the seminar series taught by faculty of the Developmental Genetics program in Fall '04. Successful completion of DG I and permission of the instructors is a prerequisite for participation in this course. The course combines a practical component and a discussion. In the practical part, experiments that have led to the discovery of important aspects of developmental biology are demonstrated and conducted by the students. For the discussion, student will read and discuss research articles pertinent to the respective laboratory session.
6 credits
Course Director: Ruth Lehmann (212) 263-8071
lehmann@saturn.med.nyu.edu
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G16. 2611 Tutorial in Neuroanatomy
This course presents the central and peripheral nervous systems in terms of anatomical localization, connectivity and functional relevance of NS organization. We will analyze sensory systems and their topographical projections into the CNS together with output as fundamental controls of behavior. The presentations will include the hierarchy of integrative centers that act to generate simple to complex reflexes and the formulation of consciousness. Thirty-two sessions will include a two hour lecture and a two hour lab each week that includes practical and didactic examinations. The sessions will begin in early February and end in early June 2005. The laboratories will utilize human brain specimens to reinforce lecture presentations. Upon completion, students should be able to: Conceptualize the human nervous system from a structural and general functional point of view; formulate a philosophical understanding of relationships between input and output systems and the integrative connectivity that binds them together within brain structures; anatomically localize structures and centers throughout the human brain and describe functional connectivity.
3 credits
Course Directors:
Dean Hillman (212) 263-7430
hillmd01@popmail.med.nyu.edu
Kalman Rubinson (212) 263-6792
kr4@nyu.edu
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G16.2616 Introduction to Parasitology
This course is an introduction to the range of eukaryotic organisms that cause disease in humans. We will cover the helminths and the protozoan parasites and we will study insects, as both agents and vectors of human disease. For each pathogen we will learn its life history, epidemiology, clinical features of the disease it causes and pathogenesis. We will also cover the basic principles of laboratory diagnosis and treatment. In the laboratory sessions students will look at prepared slides, make wet mounts of live parasites and learn to prepare thick and thin blood films for diagnosis of malaria. At the end of the course the students will work on group projects in which we will address questions such as: 1. Do helminth infections protect against the development of autoimmune diseases? 2. Will there ever be a malaria vaccine? 3. Do parasites always evolve towards less virulence?
3 credits
Course Director: Photini Sinnis (212) 263-6818
sinnip01@popmail.med.nyu.edu
Flyer
Syllabus
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G16.4115 Readings in Immunology
This 1.5 credit course will study the field of tumor immunology in depth and involve reading of original papers on the subject. We will approach the topic from a historical perspective. Primarily, students will present papers for discussion but in some cases, faculty will lead discussions on selected topics. To enroll students must have competed the introductory Immunology course. Specific time of class meetings has yet to be announced' but probably will be in the early evening, once per week, for ~ 12 weeks, beginning in February. Please email the course director if you intend to enroll (freya01@med.nyu.edu).
1.5 credits
Course Director: Alan Frey (212) 263-8129
frey01@med.nyu.edu
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G16.4403 - Advanced Techniques in Structural Biology
This course is comprised of lecture and lab sessions and will cover a range of topics/techniques including the following: x-ray protein crystallography; electron microscopy; NMR; light microscope, MRI and ultrasound.
4 credits
Course Director: Xiang-Peng Kong 212-263-7897
kong@saturn.med.nyu.edu
Syllabus
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