Course Descriptions - Fall 2004

G16. 1999 - Scientific Methods: Survival Techniques for Young Investigators in Biomedical Research
This course is required of all first year Ph.D. and M.D./Ph.D. students on a non-credit basis. In four sessions, four topics are covered that a graduate student must master in order to survive and to excel in doing research.This year we have arranged for Dr. Sun to give these four lectures in a one-day workshop on Saturday, September 11th. These lectures will cover the following topics: experimental design; literature analysis; scientific writing; oral presentation.
Course Director: Tung-Tien Sun (212-263-5685) sunt01@popmail.med.nyu.edu
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G16.2001 - Foundations of Cell and Molecular Biology I
Please see Syllabus for dates and times
This course, offered by the Cell and Molecular Biology Training Program, provides a broad overview of nucleic acid and protein metabolism and function. The fall semester begins with five weeks of Basic Molecular Biology, covering protein and nucleic acid structure, and fundamental aspects of gene expression. This initial section features intensive lectures, and weekly discussion groups. This segment of the course is followed by nine weeks of Selected Topics in Molecular Biology. The latter segment covers prokaryotic and eukaryotic transcription, chromatin structure and gene silencing, telomeres, DNA replication and recombination, protein translation, and RNA splicing and processing. Selected Topics includes two lectures and a discussion section per week. Particularly in the Selected Topics portion of the course, the reading of primary research articles is heavily emphasized. The course has a total of three in-class exams.
6 credits
Course Director: James Borowiec (212) 263-8453
borowj01@popmail.med.nyu.edu
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G16.2004 – Principles of Structural Biology
The goal of this course is to teach students what can be learned about biological processes from studying the structures of proteins and nucleic acids and the modes of interaction that underlie protein-protein and protein-nucleic acid recognition. Two 1.5 hr lectures and one 1.5 hr discussion session per week. Classes will be held in the Skirball 2nd floor conference room. Recommended text: “Introduction to Protein Structure” by Branden and Tooze. The book will be available at the NYU Medical Bookstore (~Sept. 15th) and in the library.
http://skirball.med.nyu.edu/research/sb/PSB04/
4 credits
Course Director: Steve Hubbard – (212) 263-8938
hubbard@saturn.med.nyu.edu
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G16.2005/2608 Introduction to Cellular Neuroscience
Introduction to the anatomy, cell biology, molecular structure, and physiology of neurons and glial cells. The course is structured to equip students with skills necessary to read contemporary neuroscience literature, as well as to provide a grounding in the fundamental concepts of cellular neurobiology. Emphasis is placed on basic cellular and molecular mechanisms used by neurons to receive, integrate and transmit information. Subjects covered include the structural anatomy and electrophysiological properties of neurons and glia, synaptic transmission and integration, biochemistry, physiology of neurotransmitters, and regulation of neuronal function by gene expression.
6 credits for G16.2005 and 3 credits for G16.2608
Course Director: Stewart Bloomfield (212) 263-5770
stewart.bloomfield@med.nyu.edu
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G16.2110 Advanced Readings in CMB
A tutorial in Advanced Cell and Molecular Biology will be offered in the fall semester. The tutorial will be open to a limited number of first year students with an interest in these fields. Students will form tutorials either singly or in pairs to meet with their tutor. There will be no required final exam as the organization of the tutorial will be according to each tutor.
3 credits
Course Director: Daniel Rifkin (212) 263-5234
rifkid01@popmail.med.nyu.edu
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G16.2202 Medical Microbiology
This course, divided into two parts, has been re-engineered this year for graduate students in their second year and above. Topics include: concepts in medical bacteriology; E. coli; evasion of host defenses; viral structure and replication; herpes; HIV; tumor viruses; host defenses in viral infection.
3 Credits
Course Director: Michael Garabedian (212) 263-7662
garabm01@popmail.med.nyu.edu
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G16.2213 Genetics
Transmission genetics in diploid organisms. Principles and methods of genetic analysis in diploid organisms, including Drosophila, worms, zebrafish, plants, mice and humans, will be emphasized. Classes include lectures, problem solving and discussion of primary literature. Topics include: linkage, gene interactions, mapping, mutagenesis, clonal analysis, sex determination, transgenic studies, use of mosaics, imprinting and methods of study in human genetics.
6 credits
Course director: Hannah Klein (212) 263-5778
kleinh01@popmail.med.nyu.edu
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G16.2401 Principles in Pharmacology
This course is a combination of lectures, workshops and seminars. The lectures and workshops are part of the Medical Pharmacology course for medical students. Topics include: pharmacokinetics, pharmacodynamics, drug metabolism, drug receptors and log dose response curves and autonomics.
The seminars, for graduate students only, are designed to illustrate how the general principles of pharmacology apply to clinically important areas. Example, since the function of the cardiovascular system is dependent on the autonomic system and a number of cardiovascular diseases are responsive to autonomic drugs, it will be possible to provide an in-depth understanding of the mechanism of action of autonomic drugs. Topics covered are: cardiovascular pharmacology, endocrine pharmacology and oncologic pharmacology. Each seminar will last 1 and a half hours. Instructors/Times/Locations will be announced later in the semester.
3 credits
Course Directors:
Arnold Stern (212)-263-7118
sterna01@popmail.med.nyu.edu
(Medical School portion)
Jan Sap (212) 263-7120
sapj01@popmail.med.nyu.edu
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G16.2406 - Molecular Pharmacology of Receptors
This course gives an overview of the principles in pharmacology, modern approaches to studying pharmacology and molecular aspects of receptors and signal transduction. The course is divided into three parts. The first part, introduction to molecular pharmacology, will focus on some of the basic concepts in signaling and drug-receptor interactions. The second part, modern approaches to pharmacological research, will emphasize methods such as imaging live cells, mass spectrometry, and genetic studies with C. elegans as a pharmacological tool. The third part, applications of pharmacology research, will focus on the structure and function of tyrosine kinase receptors, receptor phosphatases, G protein receptors, insulin receptors, steroid/thyroid hormone nuclear receptor gene family, glycoproteins and proteoglycans of the nervous system, recycling and internalization of receptors, exocytosis and receptors for neurotransmitters, and proteolytic processing of receptors and ligands. Classes include lectures as well as weekly discussions on selected papers.
3 credits
Course Directors:
Efrat Levy (212) 263-7113
levye01@med.nyu.edu
Jan Sap (212) 263-7120
sapj01@popmail.med.nyu.edu
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G16.2605 Research Presentations in CMB
Seminar required of all students in the CMB program.
1.5 Credits
Course Director: Lynette Wilson (212) 263-7684
wilsoe01@popmail.med.nyu.edu
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G16.2606 Tutorial in Developmental Genetics
Required of all students in the Developmental Genetics Program.
1.5 Credits
Course Director: Ruth Lehmann (212) 263-8071
lehmann@saturn.med.nyu.edu
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G16.2607 Readings in Physiology/Neuroscience
Seminar required of all 2nd and 3rd graduate students in the Physiology & Neuroscience training program.
1.5 credits
Course Director: Stewart Bloomfield (212) 263-5770
stewart.bloomfield@med.nyu.edu
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G16.2610 Developmental Genetics I
This course is an introduction into Developmental Genetics. Fundamental questions, concepts and methodologies of modern inquiry into the genetic and cellular mechanisms of development will be explored through lectures and discussion of primary literature. Topics include embryonic axis determination and the establishment of cellular asymmetry, cell specification through cell-cell interaction and region-specific gene expression, morphogenesis and organogenesis in different species.
Each week two instructors will discuss current topics in developmental biology. Each session includes a lecture and discussion part. In the discussion part students will discuss research articles related to the topic. Students will read 2 research articles as well as a review or book chapter for each session. Each student is expected to have read the articles before each session and to be able to present a summary, a detailed description of the data, underlying techniques and figures, and a critique of the research papers.
To facilitate discussion, students will meet in small groups Wednesday or Thursday to discuss the papers.
6 credits
Course Director: Ruth Lehmann (212) 263-8071
lehmann@saturn.med.nyu.edu
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G16.2611 Tutorial in Cell Biology
Required seminar for graduate students in the Cell and Molecular training program (second year and beyond)
1.5 credits
Course Director: Alan Frey (212) 263-8129
freya01@popmail.med.nyu.edu
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G16.3211 Seminar in Microbiology
Required seminar for graduate students in the Microbiology training program (second year and beyond)
1.5 credits
Course Director: Michael Garabedian (212) 263-7662
garabm01@popmail.med.nyu.edu
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G16.3311 Semianr in Pathology
Required seminar for graduate students in the Molecular Oncology and Immunology training program (second year and beyond)
1.5 credits
Course Director: David Levy (212) 263-8192
del243@popmail.med.nyu.edu
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G16.3404 Seminar in Developmental Genetics
Required seminar for graduate students in the Developmental Genetics program (second year and beyond)
1.5 credits
Course Director: Ruth Lehmann (212) 263-8071 lehmann@saturn.med.nyu.edu
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G16.3411 Seminar in Pharmacology
Required seminar for graduate students in the Pharmacology program (second year and beyond)
1.5 credits
Course Director: Jan Sap (212) 263-7120
sapj01@popmail.med.nyu.edu
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G16.3715 Seminar in Structural Biology
Required seminar for graduate students in the Structural Biology program (second year and beyond)
1.5 credits
Course Director: David Stokes (212) 263-1580
stokes@saturn.med.nyu.edu
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