Dr. Shore's research activities involve studies of the health effects of radiation. Recently he and colleagues found that cataracts were induced after fairly low levels of radiation exposure to the lens of the eye among Chernobyl cleanup workers, contrary to the regulatory dogma that cataracts were caused only by high doses. His studies have been important in documenting the degree to which radiation exposure causes breast, thyroid and skin cancer. He also directs a longitudinal study of >14,000 women to determine the associations of selected biomarkers, genetic markers and dietary factors with various cancers. He is studying the degree to which genetic variation in estrogen metabolizing genes and DNA repair genes contributes to breast cancer risk.