Leon Axel Ph.D., M.D.
Professor of Radiology, Medicine and Physiology and Neuroscience
Departments of Radiology (Radiology-Fac) and Medicine (ADMINISTRATION) and Physiology and Neuroscience
Member of NYU Radiology Associates
Member of NYU Radiology Associates
Cardiac Magnetic Resonance and CT
Research Summary
Heart disease, particularly related to ischemia and infarction, remains the principal cause of morbidity and death in the Western World. MRI and CT have the potential of playing significant roles in the evaluation of the heart, both for research and clinical applications.
The Cardiac Imaging and Analysis Laboratory (CARDIAL), under the direction of Leon Axel, is a multidisciplinary group dedicated to the development and evaluation of new cardiac imaging methods, particularly those involving quantitative characterization of such physiologic aspects as function and perfusion. This includes development of novel MRI cardiac imaging methods such as tagged MRI for regional cardiac function analysis and rapid quantitative imaging for perfusion studies, and associated programs for image analysis, as well as research on their basic and clinical applications.
The Cardiac Imaging and Analysis Laboratory (CARDIAL), under the direction of Leon Axel, is a multidisciplinary group dedicated to the development and evaluation of new cardiac imaging methods, particularly those involving quantitative characterization of such physiologic aspects as function and perfusion. This includes development of novel MRI cardiac imaging methods such as tagged MRI for regional cardiac function analysis and rapid quantitative imaging for perfusion studies, and associated programs for image analysis, as well as research on their basic and clinical applications.
Related Images
Figure 1 (left). Composite 3D display of selected intensity-corrected tagged MR images, acquired in different planes.
Figure 2 (right). Front view of biventricular finite element heart model (RV yellow, LV red) reconstructed from multiplanar tagged MRI data
Figure 2 (right). Front view of biventricular finite element heart model (RV yellow, LV red) reconstructed from multiplanar tagged MRI data
Research Information
Research Interests
Cardiac MRI, including MR image acquisition and image analysis methods development and applications to studies of cardiac physiology and pathophysiology
Research Keywords
MRI, CT, heart, cardiac function, cardiac perfusion, image processing, MRI physics, congenital heart disease



