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The objectives of this research are: (1) to develop advanced nonlinear,
porohyperviscoelastic models accurately characterizing the biomechanical
response of human soft tissues to externally applied loads; and
(2) to develop enhanced, nonlinear, 3-D finite element computational
software, capable of inputting and using the resulting biomechanical
models, in "anatomically" meshed FE models of the respective
subjects' torsos, and/or (residual) limbs to precisely compute the
stresses and strains generated in the subjects' tissues as a function
of the respective device designs and the loading applied.
The modeling methods, measurement instrumentation, and FE computational
analysis methods and software developed in this project will be
directly useable in numerous applications involving soft tissue
load bearing. As such, the devices and procedures developed will
contribute to the advancement of the science of tissue biomechanics,
and lead to significant improvements in the quality of the fit,
comfort, and function attained in load bearing devices designed
and manufactured using the techniques developed.
I. Tissue Characterization
II. MRI images for knee geometry
III. 3D FEM modeling
IV. Comparison of FEM and experimental results
I. Characterization of Residual
Limb Tissue
Measurement of trans-tibial amputee residual limb tissue mechanical
properties with the our servo controlled force/position feedback
indentor.
Amputee residual
limb (popliteal) tissue creep response to ten sequentially applied
step force loads of increasing magnitude measured over 160 sec.
To characterize bulk residual limb tissue steady state response,
the compressive, creep response steady state measurements for each
subject were fit, under a weighted least mean square error criterion,
to 2nd order Ogden elastomeric material models. To characterize
bulk residual limb tissue transient response, the initial, transient
portion of each subject's creep response measurements were fit under
a weighted least mean square error criterion to a third order weighted
exponential model. back to top
II MRI images for geometric properties
MRI was used to obtain the geometries of the bones and soft tissues

BK MRI images while wearing prosthetic socket
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III. 3D FEM modeling
Finite element (FE) models were generated from the digitized, integrated
optical and magnetic resonance images of the subjects' limbs. 4
node membrane elements were used to model the limb integument, 8
node hexahedral elements to model the underlying bulk soft tissues. back to top
IV. Comparison of FEM and experimental
results
To determine the prosthetics loads typically applied to trans-tibial
amputees' residual limbs, three representative subjects (one with
conventionally classified "firm", one with "average",
and one with "soft" durometer tissues) were selected,
and their habituated, (reasonably) "well-fitting" prostheses
were instrumented with two VA-Tekscan 1360 element P-Scan transducers
and 960 element F-Scan transducers.
Pressure Map from instrumented socket.
The resulting FE models were then validated by comparing FEA predicted
limb tissue displacements and limb surface stresses with actual
MRI measured tissue displacements and P-Scan measured interface
loads for each subject in his/her respective habituated socket/prosthesis
with specified loads applied, as shown.
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