New Elective in Clinical Pharmacology
Title: Clinical Pharmacology
Course Code: 04-39
Preceptor: Bruce N. Cronstein, MD
Telephone #: 263-6404
During this elective students will have the opportunity to review the basics
of pharmacology in the light of their recent clinical experiences in a small
group/lecture setting. In addition, the students will have the opportunity
to study in greater detail the process of new drug development and licensing
as it occurs in the United States. As drugs have been introduced for an increasing
number of novel indications the proportion of the cost of medical care spent
on pharmacologic agents has increased; students will be introduced to the principles
of pharmacoeconomics as well. In general, the elective will consist of small
group sessions held over a period of two weeks and a presentation by the student
to faculty and staff of a plan for development of a new drug.
Students will have the opportunity to review the basics of therapy in various
areas of medicine and pediatrics. In addition, students will be given the opportunity
to review the mechanism by which new drugs are developed and the effect of
pricing on use of and compliance with therapeutic regimens.
Key responsibilities of the student:
Each student will be expected to attend small group sessions and participate
in discussions of the topics presented. In addition, over the course of the
elective students will be expected to develop a plan for development of a hypothetical
new drug ranging from pre-clinical to clinical trials of the agent for the
desired indication and to present this plan to the remainder of the participating
students and faculty. Each student will work on this plan with a mentor.
The classes will be given during the day over a two week period with
the final day being devoted to student presentations.
Dates offered: Wednesday, January 30 ˜ Tuesday, February 12, 2002
Number of Students: 8
Clinical Pharmacology Elective
Ultimate assignment: A plan for the development of a new drug from pre-clinical
to Phase III studies. This can and should be taken from the literature.
Principles of Clinical Pharmacology I
Principles of Clinical Pharmacology II
Health Care Policy: What is the real cost of a drug?
New Drugs released (2000-2001)
FDA Licensing - What is a phase?
Generic Drugs and their equivalents
Clinical Pharmacology Rounds
Developing a clinical trial
Overview of biological therapies - New therapies, new challenges
Pharmacogenomics and Pharmacogenetics
Principles of Oncology Therapy
An Overview of Pharmacology in Pediatrics
Overview of nonsteroidal anti-inflammatory drugs (NSAIDs)
Overview of therapy of Rheumatic Diseases
Overview of Geriatric Therapeutics
Polypharmacy in the Elderly
Overview of antihypertensive therapy
Overview of anti-arrhythmic therapy
Overview of the therapy of ischemia
Overview of AIDS therapy
Overview of antibiotic therapy and development
Overview of asthma therapy
Overview of GI medications
Medicating the peri-operative patient
Return to Electives Catalogue