Introduction to Bioinformatics



1) Set up your account on the RCR server

Use Telnet to log into your account on the RCR server: mendel.med.nyu.edu
Your user name and password should be the same as your popmail account.

Now try to use a web browser to connect to SeqWeb. The username and password should be the same.


2) The Human Genome Sequence

The fully assembled "draft" sequences for the human genome were published in February of 2001 by both the International Human Genome Sequencing Consortium and by Celera Genomics.

This week you should read both the paper in Nature by the Sequencing Consortium and the paper in Science
by Craig Venter et al.

Nature Human Genome Issue (Feb 15, 2001)

Read the short introductory essays by David Baltimore and Wolfsberg et al.

Science Magazine Human Genome Special Issue (Feb 16, 2001)

Read the Editorial by David J. Galas.


3) View the Genome

Have a look at the Genome Browser at the Univ. of Santa Cruz. This contains the most up-to-date version of the public genome data (the basis of the Nature paper).

Try looking for the STS marker D13S171.


4) Sickle Cell/Genome Browser self-tutorial

This is a "Problem Based Learning" exercise that I developed for Introductory Biology students. It also works to introduce Bioinformatics students to the UCSC Genome Browser.

Sickle Cell exercise