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Buspirone
Augmentation of Antidepressants: Case Holders
Notes:
Buspirone Augmentation
of Antidepressants: Case Histories
- A number of case
histories have been published which show that buspirone potentiates
the SSRI fluoxetine and trazodone. Robillard, 1995; Bakish, 1991
- Three patients
who had obsessional traits, symptoms of depressive illness, marked anxiety,
and a history of eating disorders and who had prior partial responses
to fluoxetine showed dramatic improvement after buspirone addition (30
mg/d).
- The combination
of fluoxetine and buspirone produced very few side effects.
- Two elderly patients
diagnosed with major depression who were taking suboptimal levels of
trazodone (100-250 mg qhs; note optimal levels range from 400 to 600
mg qhs) achieved complete remission of symptoms with the addition of
buspirone (20 to 30 mg/d).
Bakish, 1991:749-750
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