Exploring mechanisms of FGF signalling through the lens of structural biology
Goetz, Regina; Mohammadi, Moosa
2013 Mar;14(3):166-180, Nature reviews. Molecular cell biology
— id: 271262, year: 2013, vol: 14, page: 166, stat: Journal Article,

Arterial Klotho Expression and FGF23 Effects on Vascular Calcification and Function
Lindberg, K; Olauson, H; Amin, R; Ponnusamy, A; Goetz, R; Taylor, R F; Mohammadi, M; Canfield, A; Kublickiene, K; Larsson, T E
2013 05 Apr 2013;8(4):- e60658, PLoS ONE
— id: 335012, year: 2013, vol: 8, page: , stat: Journal Article,

FGF23 regulates renal sodium handling and blood pressure
Andrukhova, O.; Slavic, S.; Zeitz, U.; Goetz, R.; Shalhoub, V.; Mohammadi, M.; Lanske, B.; Erben, R. G.
2012 DEC;51(6):S4-S4, Bone
— id: 181132, year: 2012, vol: 51, page: S4, stat: Journal Article,

FGF23 acts directly on renal proximal tubules to induce phosphaturia through activation of the ERK1/2-SGK1 signaling pathway
Andrukhova, O.; Zeitz, U.; Goetz, R.; Mohammadi, M.; Lanske, B.; Erben, R.
2012 MAY;50 1 1:S49-S50, Bone
— id: 169702, year: 2012, vol: 50 1 1, page: S49, stat: Journal Article,

Phosphaturic action of FGF23 in renal proximal tubules requires the ERK1/2 - SGK1 signaling cascade
Andrukhova, O; Zeitz, U; Goetz, R; Mohammadi, M; Lanske, B; Erben, R
2012 2012;21(1):A10-A10, Osteologie
— id: 178859, year: 2012, vol: 21, page: A10, stat: Journal Article,

FGF23 acts directly on renal proximal tubules to induce phosphaturia through activation of the ERK1/2-SGK1 signaling pathway
Andrukhova, Olena; Zeitz, Ute; Goetz, Regina; Mohammadi, Moosa; Lanske, Beate; Erben, Reinhold G
2012 Sep;51(3):621-628, Bone
— id: 175864, year: 2012, vol: 51, page: 621, stat: Journal Article,

Plasticity in Interactions of Fibroblast Growth Factor 1 (FGF1) N Terminus with FGF Receptors Underlies Promiscuity of FGF1
Beenken, Andrew; Eliseenkova, Anna V; Ibrahimi, Omar A; Olsen, Shaun K; Mohammadi, Moosa
2012 Jan;287(5):3067-3078, Journal of biological chemistry
— id: 157745, year: 2012, vol: 287, page: 3067, stat: Journal Article,

The Structural Biology of the FGF19 Subfamily
Beenken, Andrew; Mohammadi, Moosa
2012 ;728:1-24, Advances in experimental medicine & biology
— id: 159858, year: 2012, vol: 728, page: 1, stat: Journal Article,

Grb2, a double-edged sword of receptor tyrosine kinase signaling
Belov, Artur A; Mohammadi, Moosa
2012 ;5(249):pe49-pe49 pe49, Science signaling
— id: 202182, year: 2012, vol: 5, page: pe49, stat: Journal Article,

Klotho coreceptors inhibit signaling by paracrine fibroblast growth factor 8 subfamily ligands
Goetz, Regina; Ohnishi, Mutsuko; Ding, Xunshan; Kurosu, Hiroshi; Wang, Lei; Akiyoshi, Junko; Ma, Jinghong; Gai, Weiming; Sidis, Yisrael; Pitteloud, Nelly; Kuro-O, Makoto; Razzaque, Mohammed S; Mohammadi, Moosa
2012 May;32(10):1944-1954, Molecular & cellular biology
— id: 166507, year: 2012, vol: 32, page: 1944, stat: Journal Article,

Conversion of a paracrine fibroblast growth factor into an endocrine fibroblast growth factor
Goetz, Regina; Ohnishi, Mutsuko; Kir, Serkan; Kurosu, Hiroshi; Wang, Lei; Pastor, Johanne; Ma, Jinghong; Gai, Weiming; Kuro-O, Makoto; Razzaque, Mohammed S; Mohammadi, Moosa
2012 Aug;287(34):29134-29146, Journal of biological chemistry
— id: 175776, year: 2012, vol: 287, page: 29134, stat: Journal Article,

The Alternatively Spliced Acid Box Region Plays a Key Role in FGF Receptor Autoinhibition
Kalinina, Juliya; Dutta, Kaushik; Ilghari, Dariush; Beenken, Andrew; Goetz, Regina; Eliseenkova, Anna V; Cowburn, David; Mohammadi, Moosa
2012 Jan 11;20(1):77-88, Structure
— id: 149963, year: 2012, vol: 20, page: 77, stat: Journal Article,

Fibroblast growth factor 21 promotes bone loss by potentiating the effects of peroxisome proliferator-activated receptor gamma
Wei, Wei; Dutchak, Paul A; Wang, Xunde; Ding, Xunshan; Wang, Xueqian; Bookout, Angie L; Goetz, Regina; Mohammadi, Moosa; Gerard, Robert D; Dechow, Paul C; Mangelsdorf, David J; Kliewer, Steven A; Wan, Yihong
2012 Feb;109(8):3143-3148, Proceedings of the National Academy of Sciences of the United States of America
— id: 159299, year: 2012, vol: 109, page: 3143, stat: Journal Article,

Urothelial tumor initiation requires deregulation of multiple signaling pathways: implications in target-based therapies
Zhou, H; Huang, HY; Shapiro, E; Lepor, H; Huang, WC; Mohammadi, M; Mohr, I; Tang, MS; Huang, C; Wu, XR
2012 Feb;:770-780, Carcinogenesis
— id: 162340, year: 2012, vol: , page: 770, stat: Journal Article,

Regulation of serum 1,25(OH)2 vitamin D3 levels by fibroblast growth factor 23 is mediated by FGF receptors 3 and 4
Gattineni, Jyothsna; Twombley, Katherine; Goetz, Regina; Mohammadi, Moosa; Baum, Michel
2011 Aug;301(2):F371-F377, American journal of physiology. Renal physiology
— id: 137867, year: 2011, vol: 301, page: F371, stat: Journal Article,

Mutations in the FGF8 genetic network underlie a large proportion of isolated human GnRH deficiency
Miraoui, H; Feng, B; Sykiotis, G; Plummer, L; Quinton, R; Hughes, V; Guy, V V; Chanoine, J P; Crowley, W F; Dwyer, A; Sidis, Y; Mohammadi, M; Pitteloud, N
2011 June 2011;32(3):-, Endocrine reviews
— id: 159281, year: 2011, vol: 32, page: , stat: Journal Article,

Gain-of-function mutation in FGFR1 in human GnRH deficiency
Miraoui, H; Keefe, K W; Sykiotis, G; Plummer, L; Raivio, T; Dwyer, A A; Sidis, Y; Tsai, P; Mohammadi, M; Pitteloud, N
2011 June 2011;32(3):-, Endocrine reviews
— id: 159282, year: 2011, vol: 32, page: , stat: Journal Article,

Pregnane X receptor activation induces FGF19-dependent tumor aggressiveness in humans and mice
Wang, Hongwei; Venkatesh, Madhukumar; Li, Hao; Goetz, Regina; Mukherjee, Subhajit; Biswas, Arunima; Zhu, Liang; Kaubisch, Andreas; Wang, Lei; Pullman, James; Whitney, Kathleen; Kuro-o, Makoto; Roig, Andres I; Shay, Jerry W; Mohammadi, Moosa; Mani, Sridhar
2011 Aug 1;121(8):3220-3232, Journal of clinical investigation
— id: 137955, year: 2011, vol: 121, page: 3220, stat: Journal Article,

Research resource: Comprehensive expression atlas of the fibroblast growth factor system in adult mouse
Fon Tacer, Klementina; Bookout, Angie L; Ding, Xunshan; Kurosu, Hiroshi; John, George B; Wang, Lei; Goetz, Regina; Mohammadi, Moosa; Kuro-o, Makoto; Mangelsdorf, David J; Kliewer, Steven A
2010 Oct;24(10):2050-2064, Molecular endocrinology
— id: 138019, year: 2010, vol: 24, page: 2050, stat: Journal Article,

Isolated C-terminal tail of FGF23 alleviates hypophosphatemia by inhibiting FGF23-FGFR-Klotho complex formation
Goetz, Regina; Nakada, Yuji; Hu, Ming Chang; Kurosu, Hiroshi; Wang, Lei; Nakatani, Teruyo; Shi, Mingjun; Eliseenkova, Anna V; Razzaque, Mohammed S; Moe, Orson W; Kuro-o, Makoto; Mohammadi, Moosa
2010 Jan;107(1):407-412, Proceedings of the National Academy of Sciences of the United States of America
— id: 156169, year: 2010, vol: 107, page: 407, stat: Journal Article,

Regulation of collective cell migration during lacrimal gland branching morphogenesis
Gromova, A; Beenken, A; Mohammadi, M; Makarenkova, H P
2010 15 Dec 2010;21(24):-, Molecular biology of the cell
— id: 157728, year: 2010, vol: 21, page: , stat: Journal Article,

Influence of heparin mimetics on assembly of the FGF.FGFR4 signaling complex
Saxena, Krishna; Schieborr, Ulrich; Anderka, Oliver; Duchardt-Ferner, Elke; Elshorst, Bettina; Gande, Santosh Lakshmi; Janzon, Julia; Kudlinzki, Denis; Sreeramulu, Sridhar; Dreyer, Matthias K; Wendt, K Ulrich; Herbert, Corentin; Duchaussoy, Philippe; Bianciotto, Marc; Driguez, Pierre-Alexandre; Lassalle, Gilbert; Savi, Pierre; Mohammadi, Moosa; Bono, Francoise; Schwalbe, Harald
2010 Aug;285(34):26628-26640, Journal of biological chemistry
— id: 163507, year: 2010, vol: 285, page: 26628, stat: Journal Article,

Nonsense Mutations in FGF8 Gene Causing Different Degrees of Human Gonadotropin-Releasing Deficiency
Trarbach, EB; Abreu, AP; Silveira, LFG; Garmes, HM; Baptista, MTM; Teles, MG; Costa, EMF; Mohammadi, M; Pitteloud, N; Mendonca, BB; Latronico, AC
2010 JUL ;95(7):3491-3496, Journal of clinical endocrinology & metabolism
— id: 111334, year: 2010, vol: 95, page: 3491, stat: Journal Article,

New loci for congenital hypopituitarism: overlap with Kallmann syndrome
Avbelj, M; Romero, C; Tziaferi, V; McCabe, M; Zhang, CK; Sidis, Y; Plummer, L; Elting, M; Martin, C; Zou, QY; Mohammadi, M; Dattani, M; Radovick, S; Pitteloud, N
2009 NOV ;72(3):30-31, Hormone research
— id: 106178, year: 2009, vol: 72, page: 30, stat: Journal Article,

The FGF family: biology, pathophysiology and therapy
Beenken, Andrew; Mohammadi, Moosa
2009 Mar;8(3):235-253, Nature reviews. Drug discovery
— id: 95478, year: 2009, vol: 8, page: 235, stat: Journal Article,

Graded levels of FGF protein span the midbrain and can instruct graded induction and repression of neural mapping labels
Chen, Yao; Mohammadi, Moosa; Flanagan, John G
2009 Jun 25;62(6):773-780, Neuron
— id: 100779, year: 2009, vol: 62, page: 773, stat: Journal Article,

Loss-of-function fibroblast growth factor receptor-2 mutations in melanoma
Gartside, Michael G; Chen, Huaibin; Ibrahimi, Omar A; Byron, Sara A; Curtis, Amy V; Wellens, Candice L; Bengston, Ana; Yudt, Laura M; Eliseenkova, Anna V; Ma, Jinghong; Curtin, John A; Hyder, Pilar; Harper, Ursula L; Riedesel, Erica; Mann, Graham J; Trent, Jeffrey M; Bastian, Boris C; Meltzer, Paul S; Mohammadi, Moosa; Pollock, Pamela M
2009 Jan;7(1):41-54, Molecular cancer research
— id: 95479, year: 2009, vol: 7, page: 41, stat: Journal Article,

FGF23 decreases renal NaPi-2a and NaPi-2c expression and induces hypophosphatemia in vivo predominantly via FGF receptor 1
Gattineni, Jyothsna; Bates, Carlton; Twombley, Katherine; Dwarakanath, Vangipuram; Robinson, Michael L; Goetz, Regina; Mohammadi, Moosa; Baum, Michel
2009 Aug;297(2):F282-F291, American journal of physiology. Renal physiology
— id: 135000, year: 2009, vol: 297, page: F282, stat: Journal Article,

Crystal structure of a fibroblast growth factor homologous factor (FHF) defines a conserved surface on FHFs for binding and modulation of voltage-gated sodium channels
Goetz, Regina; Dover, Katarzyna; Laezza, Fernanda; Shtraizent, Nataly; Huang, Xiao; Tchetchik, Dafna; Eliseenkova, Anna V; Xu, Chong-Feng; Neubert, Thomas A; Ornitz, David M; Goldfarb, Mitchell; Mohammadi, Moosa
2009 Jun 26;284(26):17883-17896, Journal of biological chemistry
— id: 100603, year: 2009, vol: 284, page: 17883, stat: Journal Article,

Homodimerization controls the fibroblast growth factor 9 subfamily's receptor binding and heparan sulfate-dependent diffusion in the extracellular matrix
Kalinina, Juliya; Byron, Sara A; Makarenkova, Helen P; Olsen, Shaun K; Eliseenkova, Anna V; Larochelle, William J; Dhanabal, Mohanraj; Blais, Steven; Ornitz, David M; Day, Loren A; Neubert, Thomas A; Pollock, Pamela M; Mohammadi, Moosa
2009 Sep;29(17):4663-4678, Molecular & cellular biology
— id: 156085, year: 2009, vol: 29, page: 4663, stat: Journal Article,

Differential interactions of FGFs with heparan sulfate control gradient formation and branching morphogenesis
Makarenkova, Helen P; Hoffman, Matthew P; Beenken, Andrew; Eliseenkova, Anna V; Meech, Robyn; Tsau, Cindy; Patel, Vaishali N; Lang, Richard A; Mohammadi, Moosa
2009 ;2(88):ra55-ra55 ra55, Science signaling
— id: 156188, year: 2009, vol: 2, page: ra55, stat: Journal Article,

In vivo genetic evidence for klotho-dependent, fibroblast growth factor 23 (Fgf23) -mediated regulation of systemic phosphate homeostasis
Nakatani, Teruyo; Sarraj, Bara; Ohnishi, Mutsuko; Densmore, Michael J; Taguchi, Takashi; Goetz, Regina; Mohammadi, Moosa; Lanske, Beate; Razzaque, M Shawkat
2009 Feb;23(2):433-441, FASEB journal
— id: 95480, year: 2009, vol: 23, page: 433, stat: Journal Article,

FGF21 induces PGC-1alpha and regulates carbohydrate and fatty acid metabolism during the adaptive starvation response
Potthoff, Matthew J; Inagaki, Takeshi; Satapati, Santhosh; Ding, Xunshan; He, Tianteng; Goetz, Regina; Mohammadi, Moosa; Finck, Brian N; Mangelsdorf, David J; Kliewer, Steven A; Burgess, Shawn C
2009 Jun 30;106(26):10853-10858, Proceedings of the National Academy of Sciences of the United States of America
— id: 133692, year: 2009, vol: 106, page: 10853, stat: Journal Article,

Impaired fibroblast growth factor receptor 1 signaling as a cause of normosmic idiopathic hypogonadotropic hypogonadism
Raivio, Taneli; Sidis, Yisrael; Plummer, Lacey; Chen, Huaibin; Ma, Jinghong; Mukherjee, Abir; Jacobson-Dickman, Elka; Quinton, Richard; Van Vliet, Guy; Lavoie, Helene; Hughes, Virginia A; Dwyer, Andrew; Hayes, Frances J; Xu, Shuyun; Sparks, Susan; Kaiser, Ursula B; Mohammadi, Moosa; Pitteloud, Nelly
2009 Nov;94(11):4380-4390, Journal of clinical endocrinology & metabolism
— id: 133728, year: 2009, vol: 94, page: 4380, stat: Journal Article,

Compositional Analysis of Heparin/Heparan Sulfate Interacting with Fibroblast Growth Factor.Fibroblast Growth Factor Receptor Complexes
Zhang, FM; Zhang, ZQ; Lin, XF; Beenken, A; Eliseenkova, AV; Mohammadi, M; Linhardt, RJ
2009 SEP 8 ;48(35):8379-8386, Biochemistry
— id: 102304, year: 2009, vol: 48, page: 8379, stat: Journal Article,

Somatic FGF9 mutations in colorectal and endometrial carcinomas associated with membranous beta-catenin
Abdel-Rahman, Wael M; Kalinina, Juliya; Shoman, Soheir; Eissa, Saad; Ollikainen, Miina; Elomaa, Outi; Eliseenkova, Anna V; Butzow, Ralf; Mohammadi, Moosa; Peltomaki, Paivi
2008 Mar;29(3):390-397, Human mutation
— id: 95484, year: 2008, vol: 29, page: 390, stat: Journal Article,

FGF9 mutations in colorectal and endometrial cancers
Abdel-Rahman, WM; Kalinina, J; Eliseenkova, A; Eissa, S; Ollikainen, M; Elomaa, O; Butzow, R; Shoman, S; Mohammadi, M; Peltomaki, P
2008 JUL ;6(9):48-48, EJC Supplements
— id: 86831, year: 2008, vol: 6, page: 48, stat: Journal Article,

A crystallographic snapshot of tyrosine trans-phosphorylation in action
Chen, Huaibin; Xu, Chong-Feng; Ma, Jinghong; Eliseenkova, Anna V; Li, Wanqing; Pollock, Pamela M; Pitteloud, Nelly; Miller, W Todd; Neubert, Thomas A; Mohammadi, Moosa
2008 Dec 16;105(50):19660-19665, Proceedings of the National Academy of Sciences of the United States of America
— id: 90927, year: 2008, vol: 105, page: 19660, stat: Journal Article,

Decreased FGF8 signaling causes deficiency of gonadotropin-releasing hormone in humans and mice
Falardeau, John; Chung, Wilson C J; Beenken, Andrew; Raivio, Taneli; Plummer, Lacey; Sidis, Yisrael; Jacobson-Dickman, Elka E; Eliseenkova, Anna V; Ma, Jinghong; Dwyer, Andrew; Quinton, Richard; Na, Sandra; Hall, Janet E; Huot, Celine; Alois, Natalie; Pearce, Simon H S; Cole, Lindsay W; Hughes, Virginia; Mohammadi, Moosa; Tsai, Pei; Pitteloud, Nelly
2008 Aug;118(8):2822-2831, Journal of clinical investigation
— id: 95482, year: 2008, vol: 118, page: 2822, stat: Journal Article,

Inhibition of growth hormone signaling by the fasting-induced hormone FGF21
Inagaki, Takeshi; Lin, Vicky Y; Goetz, Regina; Mohammadi, Moosa; Mangelsdorf, David J; Kliewer, Steven A
2008 Jul;8(1):77-83, Cell metabolism
— id: 95483, year: 2008, vol: 8, page: 77, stat: Journal Article,

FGF-23: Beyond PI regulation
Medici, D; Sitara, D; DeLuca, S; Mohammadi, M; Kuro-o, M; Razzaque, MS; Olsen, BR; Erben, RG; Lanske, B
2008 JUN ;82(6):S23-S24, Calcified tissue international
— id: 86859, year: 2008, vol: 82, page: S23, stat: Journal Article,

FGF-23-Klotho signaling stimulates proliferation and prevents vitamin D-induced apoptosis
Medici, Damian; Razzaque, Mohammed S; Deluca, Stephelynn; Rector, Trent L; Hou, Bo; Kang, Kihwa; Goetz, Regina; Mohammadi, Moosa; Kuro-O, Makoto; Olsen, Bjorn R; Lanske, Beate
2008 Aug 11;182(3):459-465, Journal of cell biology
— id: 95481, year: 2008, vol: 182, page: 459, stat: Journal Article,

CARB 100-Structural analysis on heparin/heparan sulfate interacting with FGF center dot FGFR complexes
Zhang, FM; Zhang, ZQ; Beenken, A; Mohammadi, M; Linhardt, RJ
2008 AUG 17 ;236(2):94-94, Abstracts of papers (American Chemical Society)
— id: 106238, year: 2008, vol: 236, page: 94, stat: Journal Article,

The parathyroid is a target organ for FGF23 in rats
Ben-Dov, Iddo Z; Galitzer, Hillel; Lavi-Moshayoff, Vardit; Goetz, Regina; Kuro-o, Makoto; Mohammadi, Moosa; Sirkis, Roy; Naveh-Many, Tally; Silver, Justin
2007 Dec;117(12):4003-4008, Journal of clinical investigation
— id: 95485, year: 2007, vol: 117, page: 4003, stat: Journal Article,

A molecular brake in the kinase hinge region regulates the activity of receptor tyrosine kinases
Chen, Huaibin; Ma, Jinghong; Li, Wanqing; Eliseenkova, Anna V; Xu, Chongfeng; Neubert, Thomas A; Miller, W Todd; Mohammadi, Moosa
2007 Sep 7;27(5):717-730, Molecular cell
— id: 73939, year: 2007, vol: 27, page: 717, stat: Journal Article,

Molecular insights into the klotho-dependent, endocrine mode of action of fibroblast growth factor 19 subfamily members
Goetz, Regina; Beenken, Andrew; Ibrahimi, Omar A; Kalinina, Juliya; Olsen, Shaun K; Eliseenkova, Anna V; Xu, ChongFeng; Neubert, Thomas A; Zhang, Fuming; Linhardt, Robert J; Yu, Xijie; White, Kenneth E; Inagaki, Takeshi; Kliewer, Steven A; Yamamoto, Masaya; Kurosu, Hiroshi; Ogawa, Yasushi; Kuro-o, Makoto; Lanske, Beate; Razzaque, Mohammed S; Mohammadi, Moosa
2007 May;27(9):3417-3428, Molecular & cellular biology
— id: 71392, year: 2007, vol: 27, page: 3417, stat: Journal Article,

A homozygous missense mutation in human Klotho causes severe tumoral calcinosis, but not premature aging
Ichikawa, S; Imel, EA; Kreiter, ML; Yu, X; Mackenzie, DS; Sorenson, AH; Goetz, R; Mohammadi, M; White, KE; Econs, MJ
2007 SEP ;22(1):S33-S33, Journal of bone & mineral research
— id: 75795, year: 2007, vol: 22, page: S33, stat: Journal Article,

A homozygous missense mutation in human KLOTHO causes severe tumoral calcinosis
Ichikawa, Shoji; Imel, Erik A; Kreiter, Mary L; Yu, Xijie; Mackenzie, Donald S; Sorenson, Andrea H; Goetz, Regina; Mohammadi, Moosa; White, Kenneth E; Econs, Michael J
2007 Sep;117(9):2684-2691, Journal of clinical investigation
— id: 95486, year: 2007, vol: 117, page: 2684, stat: Journal Article,

Endocrine regulation of the fasting response by PPARalpha-mediated induction of fibroblast growth factor 21
Inagaki, Takeshi; Dutchak, Paul; Zhao, Guixiang; Ding, Xunshan; Gautron, Laurent; Parameswara, Vinay; Li, Yong; Goetz, Regina; Mohammadi, Moosa; Esser, Victoria; Elmquist, Joel K; Gerard, Robert D; Burgess, Shawn C; Hammer, Robert E; Mangelsdorf, David J; Kliewer, Steven A
2007 Jun;5(6):415-425, Cell metabolism
— id: 95488, year: 2007, vol: 5, page: 415, stat: Journal Article,

Tissue-specific expression of betaKlotho and fibroblast growth factor (FGF) receptor isoforms determines metabolic activity of FGF19 and FGF21
Kurosu, Hiroshi; Choi, Mihwa; Ogawa, Yasushi; Dickson, Addie S; Goetz, Regina; Eliseenkova, Anna V; Mohammadi, Moosa; Rosenblatt, Kevin P; Kliewer, Steven A; Kuro-o, Makoto
2007 Sep 14;282(37):26687-26695, Journal of biological chemistry
— id: 95487, year: 2007, vol: 282, page: 26687, stat: Journal Article,

BetaKlotho is required for metabolic activity of fibroblast growth factor 21
Ogawa, Yasushi; Kurosu, Hiroshi; Yamamoto, Masaya; Nandi, Animesh; Rosenblatt, Kevin P; Goetz, Regina; Eliseenkova, Anna V; Mohammadi, Moosa; Kuro-o, Makoto
2007 May 1;104(18):7432-7437, Proceedings of the National Academy of Sciences of the United States of America
— id: 95489, year: 2007, vol: 104, page: 7432, stat: Journal Article,

Digenic mutations account for variable phenotypes in idiopathic hypogonadotropic hypogonadism
Pitteloud, Nelly; Quinton, Richard; Pearce, Simon; Raivio, Taneli; Acierno, James; Dwyer, Andrew; Plummer, Lacey; Hughes, Virginia; Seminara, Stephanie; Cheng, Yu-Zhu; Li, Wei-Ping; Maccoll, Gavin; Eliseenkova, Anna V; Olsen, Shaun K; Ibrahimi, Omar A; Hayes, Frances J; Boepple, Paul; Hall, Janet E; Bouloux, Pierre; Mohammadi, Moosa; Crowley, William
2007 Feb;117(2):457-463, Journal of clinical investigation
— id: 95491, year: 2007, vol: 117, page: 457, stat: Journal Article,

Frequent activating FGFR2 mutations in endometrial carcinomas parallel germline mutations associated with craniosynostosis and skeletal dysplasia syndromes
Pollock, PM; Gartside, MG; Dejeza, LC; Powell, MA; Mallon, MA; Davies, H; Mohammadi, M; Futreal, PA; Stratton, MR; Trent, JM; Goodfellow, PJ
2007 NOV 1 ;26(50):7158-7162, Oncogene
— id: 75124, year: 2007, vol: 26, page: 7158, stat: Journal Article,

Impaired FGF signaling contributes to cleft lip and palate
Riley, Bridget M; Mansilla, M Adela; Ma, Jinghong; Daack-Hirsch, Sandra; Maher, Brion S; Raffensperger, Lisa M; Russo, Erilynn T; Vieira, Alexandre R; Dode, Catherine; Mohammadi, Moosa; Marazita, Mary L; Murray, Jeffrey C
2007 Mar 13;104(11):4512-4517, Proceedings of the National Academy of Sciences of the United States of America
— id: 95490, year: 2007, vol: 104, page: 4512, stat: Journal Article,

Hedgehogs like it sweet, too
Beenken, Andrew; Mohammadi, Moosa
2006 Nov 14;103(46):17069-17070, Proceedings of the National Academy of Sciences of the United States of America
— id: 69697, year: 2006, vol: 103, page: 17069, stat: Journal Article,

The FGF signaling pathway and human disease
Ibrahimi, OA; Mohammadi, M
2006 MAR 6 ;20(4):A694-A694, FASEB journal
— id: 63859, year: 2006, vol: 20, page: A694, stat: Journal Article,

A single amino acid substitution in the activation loop defines the decoy characteristic of VEGFR-1/FLT-1
Meyer, Rosana D; Mohammadi, Moosa; Rahimi, Nader
2006 Jan 13;281(2):867-875, Journal of biological chemistry
— id: 68522, year: 2006, vol: 281, page: 867, stat: Journal Article,

Structural basis by which alternative splicing modulates the organizer activity of FGF8 in the brain
Olsen, Shaun K; Li, James Y H; Bromleigh, Carrie; Eliseenkova, Anna V; Ibrahimi, Omar A; Lao, Zhimin; Zhang, Fuming; Linhardt, Robert J; Joyner, Alexandra L; Mohammadi, Moosa
2006 Jan 15;20(2):185-198, Genes & development
— id: 62746, year: 2006, vol: 20, page: 185, stat: Journal Article,

Mutations in fibroblast growth factor receptor 1 cause both Kallmann syndrome and normosmic idiopathic hypogonadotropic hypogonadism
Pitteloud, Nelly; Acierno, James S Jr; Meysing, Astrid; Eliseenkova, Anna V; Ma, Jinghong; Ibrahimi, Omar A; Metzger, Daniel L; Hayes, Frances J; Dwyer, Andrew A; Hughes, Virginia A; Yialamas, Maria; Hall, Janet E; Grant, Ellen; Mohammadi, Moosa; Crowley, William F Jr
2006 Apr 18;103(16):6281-6286, Proceedings of the National Academy of Sciences of the United States of America
— id: 68520, year: 2006, vol: 103, page: 6281, stat: Journal Article,

Mutations in fibroblast growth factor receptor 1 cause Kallmann syndrome with a wide spectrum of reproductive phenotypes
Pitteloud, Nelly; Meysing, Astrid; Quinton, Richard; Acierno, James S Jr; Dwyer, Andrew A; Plummer, Lacey; Fliers, Eric; Boepple, Paul; Hayes, Frances; Seminara, Stephanie; Hughes, Viriginia A; Ma, Jinghong; Bouloux, Pierre; Mohammadi, Moosa; Crowley, William F Jr
2006 Jul 25;254-255:60-69, Molecular & cellular endocrinology
— id: 68519, year: 2006, vol: 254-255, page: 60, stat: Journal Article,

Receptor specificity of the fibroblast growth factor family. The complete mammalian FGF family
Zhang, Xiuqin; Ibrahimi, Omar A; Olsen, Shaun K; Umemori, Hisashi; Mohammadi, Moosa; Ornitz, David M
2006 Jun 9;281(23):15694-15700, Journal of biological chemistry
— id: 68521, year: 2006, vol: 281, page: 15694, stat: Journal Article,

Understanding the molecular basis of apert syndrome
Ibrahimi, Omar A; Chiu, Ernest S; McCarthy, Joseph G; Mohammadi, Moosa
2005 Jan;115(1):264-270, Plastic & reconstructive surgery
— id: 56112, year: 2005, vol: 115, page: 264, stat: Journal Article,

Analysis of mutations in fibroblast growth factor (FGF) and a pathogenic mutation in FGF receptor (FGFR) provides direct evidence for the symmetric two-end model for FGFR dimerization
Ibrahimi, Omar A; Yeh, Brian K; Eliseenkova, Anna V; Zhang, Fuming; Olsen, Shaun K; Igarashi, Makoto; Aaronson, Stuart A; Linhardt, Robert J; Mohammadi, Moosa
2005 Jan;25(2):671-684, Molecular & cellular biology
— id: 50286, year: 2005, vol: 25, page: 671, stat: Journal Article,

A protein canyon in the FGF-FGF receptor dimer selects from an a la carte menu of heparan sulfate motifs
Mohammadi, Moosa; Olsen, Shaun K; Goetz, Regina
2005 Oct;15(5):506-516, Current opinion in structural biology
— id: 62599, year: 2005, vol: 15, page: 506, stat: Journal Article,

Structural basis for fibroblast growth factor receptor activation
Mohammadi, Moosa; Olsen, Shaun K; Ibrahimi, Omar A
2005 Apr;16(2):107-137, Cytokine & growth factor reviews
— id: 56118, year: 2005, vol: 16, page: 107, stat: Journal Article,

Identification of phosphopeptides by MALDI Q-TOF mass spectrometry in positive and negative ion modes after methyl esterification
Xu, Chong-Feng; Lu, Yun; Ma, Jinghong; Mohammadi, Moosa; Neubert, Thomas A
2005 Jun;4(6):809-818, Molecular & cellular proteomics
— id: 50627, year: 2005, vol: 4, page: 809, stat: Journal Article,

Analysis of the biochemical mechanisms for the endocrine actions of FGF23
Yu, X; Ibrahimi, OA; Goetz, R; Zhang, F; Davis, SI; Garringer, HJ; Linhardt, RJ; Ornitz, DM; Mohammadi, M; White, KE
2005 SEP ;20(9):S27-S27, Journal of bone & mineral research
— id: 62403, year: 2005, vol: 20, page: S27, stat: Journal Article,

Analysis of the biochemical mechanisms for the endocrine actions of fibroblast growth factor-23
Yu, Xijie; Ibrahimi, Omar A; Goetz, Regina; Zhang, Fuming; Davis, Siobhan I; Garringer, Holly J; Linhardt, Robert J; Ornitz, David M; Mohammadi, Moosa; White, Kenneth E
2005 Nov;146(11):4647-4656, Endocrinology
— id: 68523, year: 2005, vol: 146, page: 4647, stat: Journal Article,

Structure/function analysis of fibroblast growth factor homologous factors
Goldfarb, M; Shtraizent, N; Garbi, M; Schoorlemmer, J; Pardee, C; Olsen, S; Mohammadi, M
2004 AUG ;90(5):106-106, Journal of neurochemistry
— id: 46905, year: 2004, vol: 90, page: 106, stat: Journal Article,

Biochemical analysis of pathogenic ligand-dependent FGFR2 mutations suggests distinct pathophysiological mechanisms for craniofacial and limb abnormalities
Ibrahimi, Omar A; Zhang, Fuming; Eliseenkova, Anna V; Itoh, Nobuyuki; Linhardt, Robert J; Mohammadi, Moosa
2004 Oct 1;13(19):2313-2324, Human molecular genetics
— id: 48229, year: 2004, vol: 13, page: 2313, stat: Journal Article,

Proline to arginine mutations in FGF receptors 1 and 3 result in Pfeiffer and Muenke craniosynostosis syndromes through enhancement of FGF binding affinity
Ibrahimi, Omar A; Zhang, Fuming; Eliseenkova, Anna V; Linhardt, Robert J; Mohammadi, Moosa
2004 Jan 1;13(1):69-78, Human molecular genetics
— id: 48181, year: 2004, vol: 13, page: 69, stat: Journal Article,

Kinetic model for FGF, FGFR, and proteoglycan signal transduction complex assembly
Ibrahimi, Omar A; Zhang, Fuming; Hrstka, Sybil C Lang; Mohammadi, Moosa; Linhardt, Robert J
2004 May 27;43(16):4724-4730, Biochemistry
— id: 46104, year: 2004, vol: 43, page: 4724, stat: Journal Article,

Structural basis for FGF receptor activation
Mohammadi, M
2004 AUG ;90(5):106-106, Journal of neurochemistry
— id: 46904, year: 2004, vol: 90, page: 106, stat: Journal Article,

Insights into the molecular basis for fibroblast growth factor receptor autoinhibition and ligand-binding promiscuity
Olsen, Shaun K; Ibrahimi, Omar A; Raucci, Angela; Zhang, Fuming; Eliseenkova, Anna V; Yayon, Avner; Basilico, Claudio; Linhardt, Robert J; Schlessinger, Joseph; Mohammadi, Moosa
2004 Jan 27;101(4):935-940, Proceedings of the National Academy of Sciences of the United States of America
— id: 42613, year: 2004, vol: 101, page: 935, stat: Journal Article,

Targeting the ectodomain of FGFR3 in multiple meloma
Green, D; Olsen, S; Pinnell, J; Mohammadi, M
2003 NOV 16 ;102(11):681A-681A, Blood
— id: 42497, year: 2003, vol: 102, page: 681A, stat: Journal Article,

Fibroblast growth factor (FGF) homologous factors share structural but not functional homology with FGFs
Olsen, Shaun K; Garbi, Meirav; Zampieri, Niccolo; Eliseenkova, Anna V; Ornitz, David M; Goldfarb, Mitchell; Mohammadi, Moosa
2003 Sep 5;278(36):34226-34236, Journal of biological chemistry
— id: 39191, year: 2003, vol: 278, page: 34226, stat: Journal Article,

Structure-based mutational analyses in FGF7 identify new residues involved in specific interaction with FGFR2IIIb
Sher, Ifat; Yeh, Brian K; Mohammadi, Moosa; Adir, Noam; Ron, Dina
2003 Sep 25;552(2-3):150-154, FEBS letters
— id: 68524, year: 2003, vol: 552, page: 150, stat: Journal Article,

Structural basis by which alternative splicing confers specificity in fibroblast growth factor receptors
Yeh, Brian K; Igarashi, Makoto; Eliseenkova, Anna V; Plotnikov, Alexander N; Sher, Ifat; Ron, Dina; Aaronson, Stuart A; Mohammadi, Moosa
2003 Mar 4;100(5):2266-2271, Proceedings of the National Academy of Sciences of the United States of America
— id: 39297, year: 2003, vol: 100, page: 2266, stat: Journal Article,

Structural basis for fibroblast growth factor (FGF) receptor activation
Mohammadi, M
2002 Mar 20;16(4):A523-A523, FASEB journal
— id: 27502, year: 2002, vol: 16, page: A523, stat: Journal Article,

Synthesis of sulfosucrose derivatives for evaluation as regulators of fibroblast growth factor activity
Polat, T; Mohammadi, M; Linhardt, RJ
2002 NOV 4 ;43(45):8047-8049, Tetrahedron letters
— id: 55278, year: 2002, vol: 43, page: 8047, stat: Journal Article,

Structural basis for activation of fibroblast growth factor signaling by sucrose octasulfate
Yeh, Brian K; Eliseenkova, Anna V; Plotnikov, Alexander N; Green, David; Pinnell, Jared; Polat, Tulay; Gritli-Linde, Amel; Linhardt, Robert J; Mohammadi, Moosa
2002 Oct;22(20):7184-7192, Molecular & cellular biology
— id: 39589, year: 2002, vol: 22, page: 7184, stat: Journal Article,

Identification of receptor and heparin binding sites in fibroblast growth factor 4 by structure-based mutagenesis
Bellosta P; Iwahori A; Plotnikov AN; Eliseenkova AV; Basilico C; Mohammadi M
2001 Sep;21(17):5946-5957, Molecular & cellular biology
— id: 26713, year: 2001, vol: 21, page: 5946, stat: Journal Article,

Structural basis for fibroblast growth factor receptor 2 activation in Apert syndrome
Ibrahimi OA; Eliseenkova AV; Plotnikov AN; Yu K; Ornitz DM; Mohammadi M
2001 Jun 19;98(13):7182-7187, Proceedings of the National Academy of Sciences of the United States of America
— id: 48159, year: 2001, vol: 98, page: 7182, stat: Journal Article,

Crystal structure of fibroblast growth factor 9 reveals regions implicated in dimerization and autoinhibition
Plotnikov AN; Eliseenkova AV; Ibrahimi OA; Shriver Z; Sasisekharan R; Lemmon MA; Mohammadi M
2001 Feb 9;276(6):4322-4329, Journal of biological chemistry
— id: 21265, year: 2001, vol: 276, page: 4322, stat: Journal Article,

SU6668 is a potent antiangiogenic and antitumor agent that induces regression of established tumors
Laird AD; Vajkoczy P; Shawver LK; Thurnher A; Liang C; Mohammadi M; Schlessinger J; Ullrich A; Hubbard SR; Blake RA; Fong TA; Strawn LM; Sun L; Tang C; Hawtin R; Tang F; Shenoy N; Hirth KP; McMahon G; Cherrington
2000 Aug 1;60(15):4152-4160, Cancer research
— id: 20814, year: 2000, vol: 60, page: 4152, stat: Journal Article,

Crystal structures of two FGF-FGFR complexes reveal the determinants of ligand-receptor specificity
Plotnikov AN; Hubbard SR; Schlessinger J; Mohammadi M
2000 May 12;101(4):413-424, Cell
— id: 11676, year: 2000, vol: 101, page: 413, stat: Journal Article,

Crystal structure of a ternary FGF-FGFR-heparin complex reveals a dual role for heparin in FGFR binding and dimerization
Schlessinger J; Plotnikov AN; Ibrahimi OA; Eliseenkova AV; Yeh BK; Yayon A; Linhardt RJ; Mohammadi M
2000 Sep;6(3):743-750, Molecular cell
— id: 39538, year: 2000, vol: 6, page: 743, stat: Journal Article,

Structural basis for FGF receptor dimerization and activation
Plotnikov AN; Schlessinger J; Hubbard SR; Mohammadi M
1999 Sep 3;98(5):641-650, Cell
— id: 8352, year: 1999, vol: 98, page: 641, stat: Journal Article,

Autoregulatory mechanisms in protein-tyrosine kinases
Hubbard SR; Mohammadi M; Schlessinger J
1998 May 15;273(20):11987-11990, Journal of biological chemistry
— id: 7610, year: 1998, vol: 273, page: 11987, stat: Journal Article,

Crystal structure of an angiogenesis inhibitor bound to the FGF receptor tyrosine kinase domain
Mohammadi, M; Froum, S; Hamby, J M; Schroeder, M C; Panek, R L; Lu, G H; Eliseenkova, A V; Green, D; Schlessinger, J; Hubbard, S R
1998 Oct;17(20):5896-5904, EMBO journal
— id: 156649, year: 1998, vol: 17, page: 5896, stat: Journal Article,

Differential pre- and postsynaptic modulation of chemical transmission in the squid giant synapse by tyrosine phosphorylation
Llinas R; Moreno H; Sugimori M; Mohammadi M; Schlessinger J
1997 Mar 4;94(5):1990-1994, Proceedings of the National Academy of Sciences of the United States of America
— id: 9884, year: 1997, vol: 94, page: 1990, stat: Journal Article,

Structures of the tyrosine kinase domain of fibroblast growth factor receptor in complex with inhibitors
Mohammadi M; McMahon G; Sun L; Tang C; Hirth P; Yeh BK; Hubbard SR; Schlessinger J
1997 May 9;276(5314):955-960, Science
— id: 8448, year: 1997, vol: 276, page: 955, stat: Journal Article,

Structural studies of receptor tyrosine kinases
Hubbard, SR; Mohammadi, M; Schlessinger, J; Wei, L; Ellis, L; Hendrickson, WA
1996 APR 30 ;10(6):P2-P2, FASEB journal
— id: 52902, year: 1996, vol: 10, page: P2, stat: Journal Article,

Identification of six novel autophosphorylation sites on fibroblast growth factor receptor 1 and elucidation of their importance in receptor activation and signal transduction
Mohammadi M; Dikic I; Sorokin A; Burgess WH; Jaye M; Schlessinger J
1996 Mar;16(3):977-989, Molecular & cellular biology
— id: 6941, year: 1996, vol: 16, page: 977, stat: Journal Article,

Structure of the FGF receptor tyrosine kinase domain reveals a novel autoinhibitory mechanism
Mohammadi M; Schlessinger J; Hubbard SR
1996 Aug 23;86(4):577-587, Cell
— id: 7021, year: 1996, vol: 86, page: 577, stat: Journal Article,

Induction of urokinase-type plasminogen activator by fibroblast growth factor (FGF)-2 is dependent on expression of FGF receptors and does not require activation of phospholipase Cgamma1
Roghani M; Mohammadi M; Schlessinger J; Moscatelli D
1996 Dec 6;271(49):31154-31159, Journal of biological chemistry
— id: 8518, year: 1996, vol: 271, page: 31154, stat: Journal Article,

Reduced activation of RAF-1 and MAP kinase by a fibroblast growth factor receptor mutant deficient in stimulation of phosphatidylinositol hydrolysis
Huang J; Mohammadi M; Rodrigues GA; Schlessinger J
1995 Mar 10;270(10):5065-5072, Journal of biological chemistry
— id: 6645, year: 1995, vol: 270, page: 5065, stat: Journal Article,