1 Park Avenue
New York, NY 10016
Dolores Malaspina MD, MSPH is the Anita and Joseph Steckler Professor of Psychiatry at NYU and the former chairman of the NYU Department of Psychiatry.
She is the Director of a Research Division in the Department of Psychiatry, Institute for Social and Psychiatric Initiatives (InSPIRES). InSPIRES takes a cross-disciplinary approach to the prevention, early detection, treatment and cure of the social impairments at the core of conditions such as depression, schizophrenia, bipolar disorder, autism, personality disorder and aggressive behavior . They study the complex interplay of genetics with biology, environmental factors and life-course experiences. InSPIRES researchers have the unparalleled ability to interrelate relevant advances from a wide range of scientific fields.
Currently, Dr. Malaspina's main research interest is the comparative effectiveness of managing risk factors for cardiovascular disease and death vs. medication management of the relevant autonomic nervous system pathways with experimental therapeutics in persons with severe mental illness. She plans a pilot randomized controlled trial in this research area funded by the NYU-HHC Clinical and Translational Science Institute. Her goal is to build a comprehensive cardiovascular management program based at Bellevue Hospital for persons with psychiatric illness and to conduct Cost Effectiveness Research centered around health decisions affecting mentally ill urban underserved communities. She is working with a multidisciplinary team to bring these goals to fruition.
Dr. Malaspina's research has been continually funded by the National Institute of Health (NIH) for the last 25 years. She has authored more than 200 scientific papers and serves on several boards that conduct scientific reviews of grant applications and review scientific manuscripts for publication. She is an award winning mentor, training the next generation of psychiatric research scientists. She is currently a member of the DSM 5 workgroup which is redefining the criteria for psychiatric diagnoses. She has won numerous awards and honors and co-hosts a weekly radio show on Psychiatry for the Sirius/XM satellite radio channel for "Doctor Radio".
Socio-Genomics and Structural Competency
Conley, Dalton; Malaspina, Dolores. Socio-Genomics and Structural Competency. Journal of bioethical inquiry. 2016 Jun 1;13(2):193-202 (2124232)
Phenotypically distinct subtypes of psychosis accompany novel or rare variants in four different signaling genes
Kranz, Thorsten M; Berns, Adam; Shields, Jerry; Rothman, Karen; Walsh-Messinger, Julie; Goetz, Raymond R; Chao, Moses V; Malaspina, Dolores. Phenotypically distinct subtypes of psychosis accompany novel or rare variants in four different signaling genes. EBioMedicine. 2016 Apr;6:206-214 (2114482)
Searching for the Seeds of Psychosis
Malaspina, Dolores. Searching for the Seeds of Psychosis. American journal of psychiatry. 2016 May;173(5):450-451 (2100742)
Prefrontal neuronal integrity predicts symptoms and cognition in schizophrenia and is sensitive to genetic heterogeneity
Malaspina, Dolores; Kranz, Thorsten M; Heguy, Adriana; Harroch, Sheila; Mazgaj, Robert; Rothman, Karen; Berns, Adam; Hasan, Sumya; Antonius, Daniel; Goetz, Raymond; Lazar, Mariana; Chao, Moses V; Gonen, Oded. Prefrontal neuronal integrity predicts symptoms and cognition in schizophrenia and is sensitive to genetic heterogeneity. Schizophrenia research. 2016 Feb 28;172(1-3):94-100 (2009242)
Hypo-metabolism of the rostral anterior cingulate cortex associated with working memory impairment in 18 cases of schizophrenia
Mazgaj, Robert; Tal, Assaf; Goetz, Raymond; Lazar, Mariana; Rothman, Karen; Messinger, Julie Walsh; Malaspina, Dolores; Gonen, Oded. Hypo-metabolism of the rostral anterior cingulate cortex associated with working memory impairment in 18 cases of schizophrenia. Brain imaging & behavior. 2016 Mar ;10(1):115-123 (1514002)