Gene expression profiles in peripheral blood mononuclear cells of chinese nickel refinery workers with high exposures to nickel and control subjects
Arita, Adriana; Munoz, Alexandra; Chervona, Yana; Niu, Jingping; Qu, Qingshan; Zhao, Najuan; Ruan, Ye; Kiok, Kathrin; Kluz, Thomas; Sun, Hong; Clancy, Hailey A; Shamy, Magdy; Costa, Max
2013 Feb;22(2):261-269, Cancer epidemiology biomarkers & prevention
— id: 217832, year: 2013, vol: 22, page: 261, stat: Journal Article,

Global Levels of Histone Modifications in Peripheral Blood Mononuclear Cells of Subjects with Exposure to Nickel
Arita A; Niu J; Qu Q; Zhao N; Ruan Y; Nadas A; Chervona Y; Wu F; Sun H; Hayes RB; Costa M
2012 Feb;120(2):198-203, Environmental health perspectives
— id: 141421, year: 2012, vol: 120, page: 198, stat: Journal Article,

The effect of exposure to carcinogenic metals on histone tail modifications and gene expression in human subjects
Arita, Adriana; Shamy, Magdy Y; Chervona, Yana; Clancy, Harriet A; Sun, Hong; Hall, Megan N; Qu, Qingshan; Gamble, Mary V; Costa, Max
2012 Jun;26(2-3):174-178, Journal of trace elements in medicine & biology
— id: 169480, year: 2012, vol: 26, page: 174, stat: Journal Article,

Carcinogenic metals and the epigenome: understanding the effect of nickel, arsenic, and chromium
Chervona, Yana; Arita, Adriana; Costa, Max
2012 Jul;4(7):619-627, Metallomics : integrated biometal science
— id: 171119, year: 2012, vol: 4, page: 619, stat: Journal Article,

Histone modifications and cancer: biomarkers of prognosis?
Chervona, Yana; Costa, Max
2012 ;2(5):589-597, American journal of cancer research
— id: 178065, year: 2012, vol: 2, page: 589, stat: Journal Article,

The control of histone methylation and gene expression by oxidative stress, hypoxia, and metals
Chervona, Yana; Costa, Max
2012 Sep;53(5):1041-1047, Free radical biology & medicine
— id: 177142, year: 2012, vol: 53, page: 1041, stat: Journal Article,

Associations between Arsenic Exposure and Global Posttranslational Histone Modifications among Adults in Bangladesh
Chervona, Yana; Hall, Megan N; Arita, Adriana; Wu, Fen; Sun, Hong; Tseng, Hsiang-Chi; Ali, Eunus; Uddin, Mohammad Nasir; Liu, Xinhua; Zoroddu, Maria Antonietta; Gamble, Mary V; Costa, Max
2012 Dec;21(12):2252-2260, Cancer epidemiology biomarkers & prevention
— id: 202052, year: 2012, vol: 21, page: 2252, stat: Journal Article,

Nickel: a pervasive carcinogen
Clancy, Hailey A; Costa, Max
2012 Dec;8(12):1507-1509, Future Oncology
— id: 209642, year: 2012, vol: 8, page: 1507, stat: Journal Article,

Gene expression changes in human lung cells exposed to arsenic, chromium, nickel or vanadium indicate the first steps in cancer
Clancy, Hailey A; Sun, Hong; Passantino, Lisa; Kluz, Thomas; Munoz, Alexandra; Zavadil, Jiri; Costa, Max
2012 Aug;4(8):784-793, Metallomics : integrated biometal science
— id: 174389, year: 2012, vol: 4, page: 784, stat: Journal Article,

Source apportionment and elemental composition of PM2.5 and PM10 in Jeddah City, Saudi Arabia
Khodeir, Mamdouh; Shamy, Magdy; Alghamdi, Mansour; Zhong, Mianhua; Sun, Hong; Costa, Max; Chen, Lung-Chi; Maciejczyk, Polina
2012 JUL;3(3):331-340, Atmospheric pollution research
— id: 185792, year: 2012, vol: 3, page: 331, stat: Journal Article,

Elucidating the mechanisms of nickel compound uptake: A review of particulate and nano-nickel endocytosis and toxicity
Munoz, Alexandra; Costa, Max
2012 Apr;260(1):1-16, Toxicology & applied pharmacology
— id: 162953, year: 2012, vol: 260, page: 1, stat: Journal Article,

Gene expression profiling and pathway analysis of human bronchial epithelial cells exposed to airborne particulate matter collected from Saudi Arabia
Sun, Hong; Shamy, Magdy; Kluz, Thomas; Munoz, Alexandra B; Zhong, Mianhua; Laulicht, Freda; Alghamdi, Mansour A; Khoder, Mamdouh I; Chen, Lung-Chi; Costa, Max
2012 Dec;265(2):147-157, Toxicology & applied pharmacology
— id: 184912, year: 2012, vol: 265, page: 147, stat: Journal Article,

Serum taurine and risk of coronary heart disease: a prospective, nested case-control study
Wojcik, OP; Koenig, KL; Zeleniuch-Jacquotte, A; Pearte, C; Costa, M; Chen, Y
2012 Feb;:169-178, European journal of nutrition
— id: 162479, year: 2012, vol: , page: 169, stat: Journal Article,

Epigallocatechin-3-gallate (EGCG) protects against chromate-induced toxicity in vitro
Wu F; Sun H; Kluz T; Clancy HA; Kiok K; Costa M
2012 Jan;258(2):166-175, Toxicology & applied pharmacology
— id: 141420, year: 2012, vol: 258, page: 166, stat: Journal Article,

Cyclooxygenase-2 (COX-2) Mediates Arsenite Inhibition of UVB-Induced Cellular Apoptosis in Mouse Epidermal Cl41 Cells
Zuo, Z; Ouyang, W; Li, J; Costa, M; Huang, C
2012 Jul;12(6):607-616, Current cancer drug targets
— id: 170417, year: 2012, vol: 12, page: 607, stat: Journal Article,

The control of histone methylation and gene expression by oxidative stress, hypoxia and metals
Costa M.
2011 ;51:S3-S3, Free radical biology & medicine
— id: 141793, year: 2011, vol: 51, page: S3, stat: Journal Article,

Structural comparisons of non-heme Fe enzymes
Giri N.C.; Maroney M.J.; Costa M.; Chen H.; Munck E.; Stoian S.A.
2011 ;16:S218-S218, Journal of biological inorganic chemistry. JBIC
— id: 149832, year: 2011, vol: 16, page: S218, stat: Journal Article,

X-ray Absorption Spectroscopy Structural Investigation of Early Intermediates in the Mechanism of DNA Repair by Human ABH2
Giri, Nitai Charan; Sun, Hong; Chen, Haobin; Costa, Max; Maroney, Michael J
2011 Jun 7;50(22):5067-5076, Biochemistry
— id: 134095, year: 2011, vol: 50, page: 5067, stat: Journal Article,

Liprin-alpha4 Is Required for Nickel Induced Receptor Protein Tyrosine Phosphatase-Leukocyte Antigen Related Receptor F (RPTP-LAR) Activity
Kiok, Kathrin; Sun, Hong; Clancy, Hailey; Bose, Sutapa; Kluz, Thomas; Wu, Fen; Costa, Max
2011 ;6(8):e22764-e22764, PLoS ONE
— id: 136524, year: 2011, vol: 6, page: e22764, stat: Journal Article,

Comparison of Gene Expression Profiles in Chromate Transformed BEAS-2B Cells
Sun, Hong; Clancy, Harriet A; Kluz, Thomas; Zavadil, Jiri; Costa, Max
2011 ;6(3):e17982-e17982, PLoS ONE
— id: 129325, year: 2011, vol: 6, page: e17982, stat: Journal Article,

Effects of Nickel Treatment on H3K4 Trimethylation and Gene Expression
Tchou-Wong, Kam-Meng; Kiok, Kathrin; Tang, Zuojian; Kluz, Thomas; Arita, Adriana; Smith, Phillip R; Brown, Stuart; Costa, Max
2011 ;6(3):e17728-e17728, PLoS ONE
— id: 130306, year: 2011, vol: 6, page: e17728, stat: Journal Article,

Nickel Ions Inhibit Histone Demethylase JMJD1A and DNA Repair Enzyme ABH2 by Replacing the Ferrous Iron in the Catalytic Centers
Chen, Haobin; Giri, Nitai Charan; Zhang, Ronghe; Yamane, Kenichi; Zhang, Yi; Maroney, Michael; Costa, Max
2010 Mar 5;285(10):7374-7383, Journal of biological chemistry
— id: 107769, year: 2010, vol: 285, page: 7374, stat: Journal Article,

Hypoxia and nickel inhibit histone demethylase JMJD1A and repress Spry2 expression in human bronchial epithelial BEAS-2B cells
Chen, Haobin; Kluz, Thomas; Zhang, Ronghe; Costa, Max
2010 Dec;31(12):2136-2144, Carcinogenesis
— id: 114823, year: 2010, vol: 31, page: 2136, stat: Journal Article,

Effects of cellular iron deficiency on the formation of vascular endothelial growth factor and angiogenesis. Iron deficiency and angiogenesis
Eckard, Jonathan; Dai, Jisen; Wu, Jing; Jian, Jinlong; Yang, Qing; Chen, Haobin; Costa, Max; Frenkel, Krystyna; Huang, Xi
2010 ;10:28-28, Cancer cell international
— id: 114147, year: 2010, vol: 10, page: 28, stat: Journal Article,

Roles of MAPK pathway activation during cytokine induction in BEAS-2B cells exposed to fine World Trade Center (WTC) dust
Wang, Shang; Prophete, Colette; Soukup, Joleen M; Chen, Lung-Chi; Costa, Max; Ghio, Andrew; Qu, Qingshan; Cohen, Mitchell D; Chen, Haobin
2010 Oct-Dec;7(4):298-307, Journal of immunotoxicology
— id: 138258, year: 2010, vol: 7, page: 298, stat: Journal Article,

Temporal reproducibility of taurine measurements in frozen serum of healthy postmenopausal women
Wojcik, Oktawia P; Koenig, Karen L; Zeleniuch-Jacquotte, Anne; Costa, Max; Chen, Yu
2010 Sep;104(5):629-632, British journal of nutrition
— id: 132231, year: 2010, vol: 104, page: 629, stat: Journal Article,

The potential protective effects of taurine on coronary heart disease
Wojcik, Oktawia P; Koenig, Karen L; Zeleniuch-Jacquotte, Anne; Costa, Max; Chen, Yu
2010 Jan;208(1):19-25, Atherosclerosis
— id: 101575, year: 2010, vol: 208, page: 19, stat: Journal Article,

Phase II study of darinaparsin in patients with advanced hepatocellular carcinoma
Wu, Jennifer; Henderson, Charles; Feun, Lynn; Van Veldhuizen, Peter; Gold, Philip; Zheng, Hui; Ryan, Theresa; Blaszkowsky, Lawrence S; Chen, Haobin; Costa, Max; Rosenzweig, Barry; Nierodzik, MaryLynn; Hochster, Howard; Muggia, Franco; Abbadessa, Giovanni; Lewis, Jonathan; Zhu, Andrew X
2010 Oct;28(5):670-676, Investigational new drugs
— id: 138148, year: 2010, vol: 28, page: 670, stat: Journal Article,

Plk3 Functions as an Essential Component of the Hypoxia Regulatory Pathway by Direct Phosphorylation of HIF-1{alpha}
Xu, Dazhong; Yao, Yixin; Lu, Luo; Costa, Max; Dai, Wei
2010 Dec 10;285(50):38944-38950, Journal of biological chemistry
— id: 115272, year: 2010, vol: 285, page: 38944, stat: Journal Article,

JNK1 mediates degradation HIF-1alpha by a VHL-independent mechanism that involves the chaperones Hsp90/Hsp70
Zhang, Dongyun; Li, Jingxia; Costa, Max; Gao, Jimin; Huang, Chuanshu
2010 Jan 15;70(2):813-823, Cancer research
— id: 106216, year: 2010, vol: 70, page: 813, stat: Journal Article,

Hypoxia induces trimethylated H3 lysine 4 by inhibition of JARID1A demethylase
Zhou, Xue; Sun, Hong; Chen, Haobin; Zavadil, Jiri; Kluz, Thomas; Arita, Adriana; Costa, Max
2010 May 15;70(10):4214-4221, Cancer research
— id: 110413, year: 2010, vol: 70, page: 4214, stat: Journal Article,

Nickel binding to histone H4
Zoroddu, Maria Antonietta; Peana, Massimiliano; Medici, Serenella; Casella, Luigi; Monzani, Enrico; Costa, Max
2010 Jan 21;39(3):787-793, Dalton transactions (Cambridge, England : 2003)
— id: 134096, year: 2010, vol: 39, page: 787, stat: Journal Article,

Epigenetics in metal carcinogenesis: Nickel, Arsenic, Chromium and Cadmium
Arita, Adriana; Costa, Max
2009 ;1(3):222-228, Metallomics : integrated biometal science
— id: 122687, year: 2009, vol: 1, page: 222, stat: Journal Article,

A genome-wide deletion mutant screen identifies pathways affected by nickel sulfate in Saccharomyces cerevisiae
Arita, Adriana; Zhou, Xue; Ellen, Thomas P; Liu, Xin; Bai, Jingxiang; Rooney, John P; Kurtz, Adrienne; Klein, Catherine B; Dai, Wei; Begley, Thomas J; Costa, Max
2009 ;10:524-524, BMC genomics
— id: 105506, year: 2009, vol: 10, page: 524, stat: Journal Article,

Iron- and 2-oxoglutarate-dependent Dioxygenases: an emerging group of molecular targets for nickel toxicity and carcinogenicity
Chen, Haobin; Costa, Max
2009 Feb;22(1):191-196, Biometals
— id: 96242, year: 2009, vol: 22, page: 191, stat: Journal Article,

Heterochromatinization as a potential mechanism of nickel-induced carcinogenesis
Ellen, Thomas P; Kluz, Thomas; Harder, Mark E; Xiong, Judy; Costa, Max
2009 Jun 2;48(21):4626-4632, Biochemistry
— id: 101113, year: 2009, vol: 48, page: 4626, stat: Journal Article,

c-Myc mediates a hypoxia-induced decrease in acetylated histone H4
Li, Qin; Costa, Max
2009 Oct;91(10):1307-1310, Biochimie
— id: 102399, year: 2009, vol: 91, page: 1307, stat: Journal Article,

Alterations of histone modifications by cobalt compounds
Li, Qin; Ke, Qingdong; Costa, Max
2009 Jul;30(7):1243-1251, Carcinogenesis
— id: 100598, year: 2009, vol: 30, page: 1243, stat: Journal Article,

Mechanisms of c-myc degradation by nickel compounds and hypoxia
Li, Qin; Kluz, Thomas; Sun, Hong; Costa, Max
2009 ;4(12):e8531-e8531, PLoS ONE
— id: 106102, year: 2009, vol: 4, page: e8531, stat: Journal Article,

Nickel compounds induce apoptosis in human bronchial epithelial Beas-2B cells by activation of c-Myc through ERK pathway
Li, Qin; Suen, Ting-Chung; Sun, Hong; Arita, Adriana; Costa, Max
2009 Mar 1;235(2):191-198, Toxicology & applied pharmacology
— id: 96241, year: 2009, vol: 235, page: 191, stat: Journal Article,

Soluble and insoluble nickel compounds exert a differential inhibitory effect on cell growth through IKKalpha-dependent cyclin D1 down-regulation
Ouyang, Weiming; Zhang, Dongyun; Li, Jingxia; Verma, Udit N; Costa, Max; Huang, Chuanshu
2009 Jan;218(1):205-214, Journal of cellular physiology
— id: 93369, year: 2009, vol: 218, page: 205, stat: Journal Article,

Modulation of histone methylation and MLH1 gene silencing by hexavalent chromium
Sun, Hong; Zhou, Xue; Chen, Haobin; Li, Qin; Costa, Max
2009 Jun 15;237(3):258-266, Toxicology & applied pharmacology
— id: 99233, year: 2009, vol: 237, page: 258, stat: Journal Article,

Covalent modifications of histones during mitosis and meiosis
Xu, Dazhong; Bai, Jingxiang; Duan, Qing; Costa, Max; Dai, Wei
2009 Nov 15;8(22):3688-3694, Cell cycle
— id: 105250, year: 2009, vol: 8, page: 3688, stat: Journal Article,

A genome-wide screen in Saccharomyces cerevisiae reveals pathways affected by arsenic toxicity
Zhou, Xue; Arita, Adriana; Ellen, Thomas P; Liu, Xin; Bai, Jingxiang; Rooney, John P; Kurtz, Adrienne D; Klein, Catherine B; Dai, Wei; Begley, Thomas J; Costa, Max
2009 Nov;94(5):294-307, Genomics
— id: 104719, year: 2009, vol: 94, page: 294, stat: Journal Article,

Effects of nickel, chromate, and arsenite on histone 3 lysine methylation
Zhou, Xue; Li, Qin; Arita, Adriana; Sun, Hong; Costa, Max
2009 Apr 1;236(1):78-84, Toxicology & applied pharmacology
— id: 97963, year: 2009, vol: 236, page: 78, stat: Journal Article,

Phosphorylation of H3S10 blocks the access of H3K9 by specific antibodies and histone methyltransferase. Implication in regulating chromatin dynamics and epigenetic inheritance during mitosis
Duan, Qing; Chen, Haobin; Costa, Max; Dai, Wei
2008 Nov 28;283(48):33585-33590, Journal of biological chemistry
— id: 91974, year: 2008, vol: 283, page: 33585, stat: Journal Article,

NDRG1, a growth and cancer related gene: regulation of gene expression and function in normal and disease states
Ellen, Thomas P; Ke, Qingdong; Zhang, Ping; Costa, Max
2008 Jan;29(1):2-8, Carcinogenesis
— id: 76760, year: 2008, vol: 29, page: 2, stat: Journal Article,

Nickel compounds induce histone ubiquitination by inhibiting histone deubiquitinating enzyme activity
Ke, Qingdong; Ellen, Thomas P; Costa, Max
2008 Apr 15;228(2):190-199, Toxicology & applied pharmacology
— id: 79243, year: 2008, vol: 228, page: 190, stat: Journal Article,

Nickel compounds induce phosphorylation of histone H3 at serine 10 by activating JNK-MAPK pathway
Ke, Qingdong; Li, Qin; Ellen, Thomas P; Sun, Hong; Costa, Max
2008 Jun;29(6):1276-1281, Carcinogenesis
— id: 80302, year: 2008, vol: 29, page: 1276, stat: Journal Article,

CrVI exposure and biomarkers: Cr in erythrocytes in relation to exposure and polymorphisms of genes encoding anion transport proteins
Qu, Qingshan; Li, Xiaomei; An, Feiyun; Jia, Guang; Liu, Lanzeng; Watanabe-Meserve, Hiroko; Koenig, Karen; Cohen, Beverly; Costa, Max; Roy, Nirmal; Zhong, Mianhua; Chen, Lung Chi; Liu, Suhua; Yan, Lei
2008 Aug;13(5):467-477, Biomarkers
— id: 93384, year: 2008, vol: 13, page: 467, stat: Journal Article,

Polo-like kinase 3 functions as a tumor suppressor and is a negative regulator of hypoxia-inducible factor-1 alpha under hypoxic conditions
Yang, Yali; Bai, Jingxiang; Shen, Rulong; Brown, Sharron A N; Komissarova, Elena; Huang, Ying; Jiang, Ning; Alberts, Gregory F; Costa, Max; Lu, Luo; Winkles, Jeffrey A; Dai, Wei
2008 Jun 1;68(11):4077-4085, Cancer research
— id: 81058, year: 2008, vol: 68, page: 4077, stat: Journal Article,

Arsenite alters global histone H3 methylation
Zhou, Xue; Sun, Hong; Ellen, Thomas P; Chen, Haobin; Costa, Max
2008 Sep;29(9):1831-1836, Carcinogenesis
— id: 93297, year: 2008, vol: 29, page: 1831, stat: Journal Article,

Nickel compounds
Cohen M; Klein C; Costa M
Environmental and occupational medicine Philadelphia : Wolters Kluwer/Lippincott Williams & Wilkins, 2007,
— id: 4440, year: 2007, vol: , page: ?, stat: Chapter,

Chromium compounds
Cohen MD; Costa M
Environmental and occupational medicine Philadelphia : Wolters Kluwer/Lippincott Williams & Wilkins, 2007,
— id: 4439, year: 2007, vol: , page: ?, stat: Chapter,

Molecular mechanisms of metal toxicity and carcinogenicity
Davidson T; Ke Q; Costa M
Handbook on the toxicology of metals Burlington MA : Academic Press, 2007,
— id: 4438, year: 2007, vol: , page: 79, stat: Chapter,

Overview of chromium (III) toxicology
Ke Q; Costa M
Nutritional biochemisty of chromium (III) Amsterdam : Elsevier, 2007,
— id: 4441, year: 2007, vol: , page: 257, stat: Chapter,

Carcinogenicity of metal compounds
Ke Q; Costa M; Kazantzis G
Handbook on the toxicology of metals Burlington MA : Academic Press, 2007,
— id: 4436, year: 2007, vol: , page: 177, stat: Chapter,

Fluorescent tracking of nickel ions in human cultured cells
Ke, Qingdong; Davidson, Todd; Kluz, Thomas; Oller, Adriana; Costa, Max
2007 Feb 15;219(1):18-23, Toxicology & applied pharmacology
— id: 71340, year: 2007, vol: 219, page: 18, stat: Journal Article,

Nickel
Klein CB; Costa M
Handbook on the toxicology of metals Burlington MA : Academic Press, 2007,
— id: 4437, year: 2007, vol: , page: 743, stat: Chapter,

Correlation of N-myc downstream-regulated gene 1 expression with clinical outcomes of colorectal cancer patients of different race/ethnicity
Koshiji, Minori; Kumamoto, Kensuke; Morimura, Keiichirou; Utsumi, Yasufumi; Aizawa, Michiko; Hoshino, Masami; Ohki, Shinji; Takenoshita, Seiichi; Costa, Max; Commes, Therese; Piquemal, David; Harris, Curtis-C; Tchou-Wong, Kam-Meng
2007 May 28;13(20):2803-2810, World journal of gastroenterology : WJG
— id: 73067, year: 2007, vol: 13, page: 2803, stat: Journal Article,

Chromium
Langard S; Costa M
Handbook on the toxicology of metals Burlington MA : Academic Press, 2007,
— id: 4435, year: 2007, vol: , page: 487, stat: Chapter,

Dietary chromium and nickel enhance UV-carcinogenesis in skin of hairless mice
Uddin, Ahmed N; Burns, Fredric J; Rossman, Toby G; Chen, Haobin; Kluz, Thomas; Costa, Max
2007 Jun 15;221(3):329-338, Toxicology & applied pharmacology
— id: 72149, year: 2007, vol: 221, page: 329, stat: Journal Article,

JNK1, but not JNK2, is required for COX-2 induction by nickel compounds
Zhang, Dongyun; Li, Jingxia; Wu, Kangjian; Ouyang, Weiming; Ding, Jin; Liu, Zheng-gang; Costa, Max; Huang, Chuanshu
2007 Apr;28(4):883-891, Carcinogenesis
— id: 68994, year: 2007, vol: 28, page: 883, stat: Journal Article,

Egr-1 mediates hypoxia-inducible transcription of the NDRG1 gene through an overlapping Egr-1/Sp1 binding site in the promoter
Zhang, Ping; Tchou-Wong, Kam-Meng; Costa, Max
2007 Oct 1;67(19):9125-9133, Cancer research
— id: 74580, year: 2007, vol: 67, page: 9125, stat: Journal Article,

Sequence specificity of Cr(III)-DNA adduct formation in the p53 gene: NGG sequences are preferential adduct-forming sites
Arakawa, Hirohumi; Wu, Feng; Costa, Max; Rom, William; Tang, Moon-Shong
2006 Mar;27(3):639-645, Carcinogenesis
— id: 63597, year: 2006, vol: 27, page: 639, stat: Journal Article,

Molecular mechanisms of nickel toxicity and carcinogenicity
Chen H; Davidson TL; Li Q; Ke Q; Costa M
2006 ;9:391-395, Metal ions in biology & medicine = Les ions metalliques en biologie et en medicine
— id: 72796, year: 2006, vol: 9, page: 391, stat: Journal Article,

Effect of soluble nickel on cellular energy metabolism in A549 cells
Chen, Haobin; Costa, Max
2006 Oct;231(9):1474-1480, Experimental biology & medicine
— id: 68893, year: 2006, vol: 231, page: 1474, stat: Journal Article,

Nickel ions increase histone H3 lysine 9 dimethylation and induce transgene silencing
Chen, Haobin; Ke, Qingdong; Kluz, Thomas; Yan, Yan; Costa, Max
2006 May;26(10):3728-3737, Molecular & cellular biology
— id: 64479, year: 2006, vol: 26, page: 3728, stat: Journal Article,

Hypoxic stress induces dimethylated histone H3 lysine 9 through histone methyltransferase G9a in mammalian cells
Chen, Haobin; Yan, Yan; Davidson, Todd L; Shinkai, Yoichi; Costa, Max
2006 Sep 15;66(18):9009-9016, Cancer research
— id: 68894, year: 2006, vol: 66, page: 9009, stat: Journal Article,

Response to comments by post and stern on article "Toxicity and carcinogenicity of chromium compounds in humans"
Costa, M; Klein, C
2006 OCT ;36(9):779-779, Critical reviews in toxicology
— id: 68959, year: 2006, vol: 36, page: 779, stat: Journal Article,

Toxicity and carcinogenicity of chromium compounds in humans
Costa, Max; Klein, Catherine B
2006 Feb;36(2):155-163, Critical reviews in toxicology
— id: 64671, year: 2006, vol: 36, page: 155, stat: Journal Article,

Soluble nickel inhibits HIF-prolyl-hydroxylases creating persistent hypoxic signaling in A549 cells
Davidson, Todd L; Chen, Haobin; Di Toro, Dominic M; D'Angelo, Gisela; Costa, Max
2006 Jul;45(7):479-489, Molecular carcinogenesis
— id: 67001, year: 2006, vol: 45, page: 479, stat: Journal Article,

Nickel compounds render anti-apoptotic effect to human bronchial epithelial Beas-2B cells by induction of cyclooxygenase-2 through an IKKbeta/p65-dependent and IKKalpha- and p50-independent pathway
Ding, Jin; Zhang, Xinhai; Li, Jingxia; Song, Lun; Ouyang, Weiming; Zhang, Dongyun; Xue, Caifang; Costa, Max; Melendez, J Andres; Huang, Chuanshu
2006 Dec;281(51):39022-39032, Journal of biological chemistry
— id: 156051, year: 2006, vol: 281, page: 39022, stat: Journal Article,

DMT1: which metals does it transport?
Garrick, Michael D; Singleton, Steven T; Vargas, Farida; Kuo, H-C; Zhao, Lin; Knopfel, Martin; Davidson, Todd; Costa, Max; Paradkar, Prasad; Roth, Jerome A; Garrick, Laura M
2006 ;39(1):79-85, Biological research
— id: 68997, year: 2006, vol: 39, page: 79, stat: Journal Article,

Effect of metal ions on HIF-1alpha and Fe homeostasis in human A549 cells
Kang, Gi Soo; Li, Qin; Chen, Haobin; Costa, Max
2006 Nov 7;610(1-2):48-55, Mutation research
— id: 68895, year: 2006, vol: 610, page: 48, stat: Journal Article,

Hypoxia-Inducible Factor-1 (HIF-1)
Ke, Qingdong; Costa, Max
2006 Nov;70(5):1469-1480, Molecular pharmacology
— id: 68996, year: 2006, vol: 70, page: 1469, stat: Journal Article,

Alterations of histone modifications and transgene silencing by nickel chloride
Ke, Qingdong; Davidson, Todd; Chen, Haobin; Kluz, Thomas; Costa, Max
2006 Jul;27(7):1481-1488, Carcinogenesis
— id: 67527, year: 2006, vol: 27, page: 1481, stat: Journal Article,

Essential role of ROS-mediated NFAT activation in TNF-alpha induction by crystalline silica exposure
Ke, Qingdong; Li, Jingxia; Ding, Jin; Ding, Min; Wang, Liying; Liu, Bingci; Costa, Max; Huang, Chuanshu
2006 Aug;291(2):L257-L264, American journal of physiology. Lung cellular & molecular physiology
— id: 68743, year: 2006, vol: 291, page: L257, stat: Journal Article,

Effects of 12 metal ions on iron regulatory protein 1 (IRP-1) and hypoxia-inducible factor-1 alpha (HIF-1alpha) and HIF-regulated genes
Li, Qin; Chen, Haobin; Huang, Xi; Costa, Max
2006 Jun 15;213(3):245-255, Toxicology & applied pharmacology
— id: 65794, year: 2006, vol: 213, page: 245, stat: Journal Article,

Altered iron homeostasis involvement in arsenite-mediated cell transformation
Wu, Jing; Eckard, Jonathan; Chen, Haobin; Costa, Max; Frenkel, Krystyna; Huang, Xi
2006 Feb 1;40(3):444-452, Free radical biology & medicine
— id: 64134, year: 2006, vol: 40, page: 444, stat: Journal Article,

Nickel decreases cellular iron level and converts cytosolic aconitase to iron-regulatory protein 1 in A549 cells
Chen, Haobin; Davidson, Todd; Singleton, Steven; Garrick, Michael D; Costa, Max
2005 Aug 15;206(3):275-287, Toxicology & applied pharmacology
— id: 57867, year: 2005, vol: 206, page: 275, stat: Journal Article,

Nickel carcinogenesis: epigenetics and hypoxia signaling
Costa, Max; Davidson, Todd L; Chen, Haobin; Ke, Qingdong; Zhang, Ping; Yan, Yan; Huang, Chuanshu; Kluz, Thomas
2005 Dec 30;592(1-2):79-88, Mutation research
— id: 67383, year: 2005, vol: 592, page: 79, stat: Journal Article,

Soluble nickel interferes with cellular iron homeostasis
Davidson, Todd; Chen, Haobin; Garrick, Michael D; D'Angelo, Gisela; Costa, Max
2005 Nov;279(1-2):157-162, Molecular & cellular biochemistry
— id: 68896, year: 2005, vol: 279, page: 157, stat: Journal Article,

Down-regulation of the expression of the FIH-1 and ARD-1 genes at the transcriptional level by nickel and cobalt in the human lung adenocarcinoma A549 cell line
Ke, Qingdong; Kluz, Thomas; Costa, Max
2005 Apr;2(1):10-13, International Journal of Environmental Research & Public Health
— id: 66459, year: 2005, vol: 2, page: 10, stat: Journal Article,

ERKs activation and calcium signaling are both required for VEGF induction by vanadium in mouse epidermal Cl41 cells
Li, Jingxia; Tong, Qiangsong; Shi, Xianglin; Costa, Max; Huang, Chuanshu
2005 Nov;279(1-2):25-33, Molecular & cellular biochemistry
— id: 70870, year: 2005, vol: 279, page: 25, stat: Journal Article,

Carcinogenic effect of nickel compounds
Lu, Haitian; Shi, Xianglin; Costa, Max; Huang, Chuanshu
2005 Nov;279(1-2):45-67, Molecular & cellular biochemistry
— id: 70872, year: 2005, vol: 279, page: 45, stat: Journal Article,

In vivo and in vitro analysis of the human tissue-type plasminogen activator gene promoter in neuroblastomal cell lines: evidence for a functional upstream kappaB element
Lux, W; Klobeck, H-G; Daniel, P B; Costa, M; Medcalf, R L; Schleuning, W-D
2005 May;3(5):1009-1017, Journal of thrombosis & haemostasis : JTH
— id: 171777, year: 2005, vol: 3, page: 1009, stat: Journal Article,

Essential role of PI-3K, ERKs and calcium signal pathways in nickel-induced VEGF expression
Ouyang, Weiming; Li, Jingxia; Shi, Xianglin; Costa, Max; Huang, Chuanshu
2005 Nov;279(1-2):35-43, Molecular & cellular biochemistry
— id: 70871, year: 2005, vol: 279, page: 35, stat: Journal Article,

Altered N-myc downstream-regulated gene 1 protein expression in African-American compared with caucasian prostate cancer patients
Caruso, Robert P; Levinson, Benjamin; Melamed, Jonathan; Wieczorek, Rosemary; Taneja, Samir; Polsky, David; Chang, Caroline; Zeleniuch-Jacquotte, Anne; Salnikow, Konstantin; Yee, Herman; Costa, Max; Osman, Iman
2004 Jan 1;10(1 Pt 1):222-227, Clinical cancer research
— id: 44771, year: 2004, vol: 10, page: 222, stat: Journal Article,

Research profile. Max Costa
Costa, Max
2004 May;6(5):57N-59N, Journal of environmental monitoring. JEM
— id: 134097, year: 2004, vol: 6, page: 57N, stat: Journal Article,

Exposure to chromium (VI) in the drinking water increases susceptibility to UV-induced skin tumors in hairless mice
Davidson, Todd; Kluz, Thomas; Burns, Fredric; Rossman, Toby; Zhang, Qunwei; Uddin, Ahmed; Nadas, Arthur; Costa, Max
2004 May 1;196(3):431-437, Toxicology & applied pharmacology
— id: 43216, year: 2004, vol: 196, page: 431, stat: Journal Article,

Molecular mechanisms of arsenic carcinogenesis
Huang, Chuanshu; Ke, Qingdong; Costa, Max; Shi, Xianglin
2004 Jan;255(1-2):57-66, Molecular & cellular biochemistry
— id: 42693, year: 2004, vol: 255, page: 57, stat: Journal Article,

Differential effects of polycyclic aromatic hydrocarbons on transactivation of AP-1 and NF-kappaB in mouse epidermal cl41 cells
Li, Jingxia; Chen, Haobin; Ke, Qingdong; Feng, Zhaohui; Tang, Moon-Shong; Liu, Bingci; Amin, Shantu; Costa, Max; Huang, Chuanshu
2004 Jun;40(2):104-115, Molecular carcinogenesis
— id: 42690, year: 2004, vol: 40, page: 104, stat: Journal Article,

PI-3K and Akt are mediators of AP-1 induction by 5-MCDE in mouse epidermal Cl41 cells
Li, Jingxia; Chen, Haobin; Tang, Moon-Shong; Shi, Xianglin; Amin, Shantu; Desai, Dhimant; Costa, Max; Huang, Chuanshu
2004 Apr 12;165(1):77-86, Journal of cell biology
— id: 42691, year: 2004, vol: 165, page: 77, stat: Journal Article,

Nickel compounds act through phosphatidylinositol-3-kinase/Akt-dependent, p70(S6k)-independent pathway to induce hypoxia inducible factor transactivation and Cap43 expression in mouse epidermal Cl41 cells
Li, Jingxia; Davidson, Gerard; Huang, Yi; Jiang, Bing-Hua; Shi, Xianglin; Costa, Max; Huang, Chuanshu
2004 Jan 1;64(1):94-101, Cancer research
— id: 42615, year: 2004, vol: 64, page: 94, stat: Journal Article,

Activation of aPKC is required for vanadate-induced phosphorylation of protein kinase B (Akt), but not p70S6k in mouse epidermal JB6 cells
Li, Jingxia; Dokka, Sujatha; Wang, Liying; Shi, Xianglin; Castranova, Vincent; Yan, Yan; Costa, Max; Huang, Chuanshu
2004 Jan;255(1-2):217-225, Molecular & cellular biochemistry
— id: 42692, year: 2004, vol: 255, page: 217, stat: Journal Article,

Chromatin immunoprecipitation assays
Yan, Yan; Chen, Haobin; Costa, Max
2004 ;287(8):9-19, Methods in molecular biology
— id: 46102, year: 2004, vol: 287, page: 9, stat: Journal Article,

Nickel-induced 1,4-alpha-glucan branching enzyme 1 up-regulation via the hypoxic signaling pathway
Zhao, Jianhua; Chen, Haobin; Davidson, Todd; Kluz, Thomas; Zhang, Qunwei; Costa, Max
2004 Jun 1;196(3):404-409, Toxicology & applied pharmacology
— id: 46203, year: 2004, vol: 196, page: 404, stat: Journal Article,

Nickel-induced down-regulation of serpin by hypoxic signaling
Zhao, Jianhua; Yan, Yan; Salnikow, Konstantin; Kluz, Thomas; Costa, Max
2004 Jan 1;194(1):60-68, Toxicology & applied pharmacology
— id: 42617, year: 2004, vol: 194, page: 60, stat: Journal Article,

Nickel(II) binding to Cap43 protein fragments
Zoroddu, M A; Peana, M; Kowalik-Jankowska, T; Kozlowski, H; Costa, M
2004 Jun;98(6):931-939, Journal of inorganic biochemistry
— id: 141435, year: 2004, vol: 98, page: 931, stat: Journal Article,

Different mechanisms in suppressing MTH expression by nickel chloride and cobalt chloride
Chen, H; Yan, Y; Kluz, T; Costa, M
2003 MAR ;72(5):1050-419, Toxicological sciences
— id: 98229, year: 2003, vol: 72, page: 1050, stat: Journal Article,

Potential hazards of hexavalent chromate in our drinking water
Costa, Max
2003 Apr 1;188(1):1-5, Toxicology & applied pharmacology
— id: 111733, year: 2003, vol: 188, page: 1, stat: Journal Article,

Molecular mechanisms of nickel carcinogenesis: gene silencing by nickel delivery to the nucleus and gene activation/inactivation by nickel-induced cell signaling
Costa, Max; Yan, Yan; Zhao, Daoji; Salnikow, Konstantin
2003 Apr;5(2):222-223, Journal of environmental monitoring. JEM
— id: 34642, year: 2003, vol: 5, page: 222, stat: Journal Article,

Regulation of HIF transactivation and CAP43 expression by nickel compounds through PI-3K/AKT dependent, P70S6K-independent pathway
Davidson, G; Li, J; Huang, Y; Costa, M; Huang, C
2003 MAR ;72(1):106-106, Toxicological sciences
— id: 38494, year: 2003, vol: 72, page: 106, stat: Journal Article,

Inhibition of phase I and phase II metabolic enzymes in vitro by nickel chloride
Davidson, TL; Salnikow, K; Costa, M
2003 MAR ;72(5):1058-419, Toxicological sciences
— id: 98230, year: 2003, vol: 72, page: 1058, stat: Journal Article,

Hypoxia inducible factor-1 alpha-independent suppression of aryl hydrocarbon receptor-regulated genes by nickel
Davidson, Todd; Salnikow, Konstantin; Costa, Max
2003 Dec;64(6):1485-1493, Molecular pharmacology
— id: 44774, year: 2003, vol: 64, page: 1485, stat: Journal Article,

Chromium(VI) exposure enhances polycyclic aromatic hydrocarbon-DNA binding at the p53 gene in human lung cells
Feng, Zhaohui; Hu, Wenwei; Rom, William N; Costa, Max; Tang, Moon-Shong
2003 Apr;24(4):771-778, Carcinogenesis
— id: 39234, year: 2003, vol: 24, page: 771, stat: Journal Article,

Inhibition and reversal of cellular transformation by the histone deacetylase inhibitor trichostatin A
Kluz, T; Zhang, Q; Salnikow, K; Costa, M
2003 MAR ;72(1):212-212, Toxicological sciences
— id: 38496, year: 2003, vol: 72, page: 212, stat: Journal Article,

The analysis of transcriptional regulation of nickel-inducible gene Cap43
Salnikow, K; Zhang, P; Costa, M
2003 MAR ;72(1):234-234, Toxicological sciences
— id: 38500, year: 2003, vol: 72, page: 234, stat: Journal Article,

GeneChip analysis of signaling pathways effected by nickel
Salnikow, Konstantin; Davidson, Todd; Kluz, Thomas; Chen, Haobin; Zhou, Daoji; Costa, Max
2003 Apr;5(2):206-209, Journal of environmental monitoring. JEM
— id: 34643, year: 2003, vol: 5, page: 206, stat: Journal Article,

The involvement of hypoxia-inducible transcription factor-1-dependent pathway in nickel carcinogenesis
Salnikow, Konstantin; Davidson, Todd; Zhang, Qunwei; Chen, Lung Chi; Su, Weichen; Costa, Max
2003 Jul 1;63(13):3524-3530, Cancer research
— id: 39165, year: 2003, vol: 63, page: 3524, stat: Journal Article,

Epigenetics and the environment
Sutherland, Jessica E; Costa, Max
2003 Mar;983:151-160, Annals of the New York Academy of Sciences
— id: 134098, year: 2003, vol: 983, page: 151, stat: Journal Article,

Analysis of chromatin structure in nickel silenced G12 Chinese hamster cells
Yan, Y; Kluz, T; Zhang, P; Chen, H; Costa, M
2003 MAR ;72(1):216-216, Toxicological sciences
— id: 38497, year: 2003, vol: 72, page: 216, stat: Journal Article,

Analysis of specific lysine histone H3 and H4 acetylation and methylation status in clones of cells with a gene silenced by nickel exposure
Yan, Yan; Kluz, Thomas; Zhang, Ping; Chen, Hao-bin; Costa, Max
2003 Aug 1;190(3):272-277, Toxicology & applied pharmacology
— id: 39116, year: 2003, vol: 190, page: 272, stat: Journal Article,

Downregulation of a zinc finger protein-ZFP61 by Ni in mouse cells in vitro and in vivo
Zhang, P; Costa, M
2003 MAR ;72(1):234-234, Toxicological sciences
— id: 38501, year: 2003, vol: 72, page: 234, stat: Journal Article,

Chromate induces the HGPRT gene silencing by DNA methylation: A new epigenetic mechanism for chromate carcinogenesis
Zhang, Q; Kluz, T; Salnikow, K; Costa, M
2003 MAR ;72(1):234-234, Toxicological sciences
— id: 38499, year: 2003, vol: 72, page: 234, stat: Journal Article,

Inhibition and reversal of nickel-induced transformation by the histone deacetylase inhibitor trichostatin A
Zhang, Qunwei; Salnikow, Konstantin; Kluz, Thomas; Chen, Lung Chi; Su, Wei Cheng; Costa, Max
2003 Nov 1;192(3):201-211, Toxicology & applied pharmacology
— id: 44775, year: 2003, vol: 192, page: 201, stat: Journal Article,

Down regulation of a serine proteinase inhibitor by Ni and Co is dependent on hypoxia inducible factor signalling
Zhao, J; Yan, Y; Costa, M
2003 MAR ;72(1):234-234, Toxicological sciences
— id: 38502, year: 2003, vol: 72, page: 234, stat: Journal Article,

Molecular mechanisms of nickel carcinogenesis
Cangul, H; Broday, L; Salnikow, K; Sutherland, J; Peng, W; Zhang, Q; Poltaratsky, V; Yee, H; Zoroddu, M A; Costa, M
2002 Feb 28;127(1-3):69-75, Toxicology letters
— id: 34648, year: 2002, vol: 127, page: 69, stat: Journal Article,

Enhanced expression of a novel protein in human cancer cells: a potential aid to cancer diagnosis
Cangul, H; Salnikow, K; Yee, H; Zagzag, D; Commes, T; Costa, M
2002 ;18(2):87-96, Cell biology & toxicology
— id: 34649, year: 2002, vol: 18, page: 87, stat: Journal Article,

Enhanced overexpression of an HIF-1/hypoxia-related protein in cancer cells
Cangul, Hakan; Salnikow, Konstantin; Yee, Herman; Zagzag, David; Commes, Therese; Costa, Max
2002 Oct;110 Suppl 5(2):783-788, Environmental health perspectives
— id: 34644, year: 2002, vol: 110 Suppl 5, page: 783, stat: Journal Article,

Use of XAS for the elucidation of metal structure and function: applications to nickel biochemistry, molecular toxicology, and carcinogenesis
Carrington, Paul E; Al-Mjeni, Faizah; Zoroddu, Maria A; Costa, Max; Maroney, Michael J
2002 Oct;110 Suppl 5:705-708, Environmental health perspectives
— id: 134099, year: 2002, vol: 110 Suppl 5, page: 705, stat: Journal Article,

Molecular responses of mammalian cells to nickel and chromate exposure
Costa M; Salnikow K; Sutherland JE; Klutz T; Peng W; Tang M-S
Biomarkers of environmentally associated disease : technologies, concepts, and perspectives Boca Raton FL : Lewis Publishers, 2002,
— id: 4434, year: 2002, vol: , page: 261, stat: Chapter,

Preface - Third International Meeting on the Molecular Mechanisms of Metal Toxicity and Carcinogenicity
Costa, M; Zoroddu, MA; Suk, WA; Thompson, C; Rossman, T
2002 OCT ;110(3):687-687, Environmental health perspectives
— id: 33048, year: 2002, vol: 110, page: 687, stat: Journal Article,

Molecular mechanisms of nickel carcinogenesis
Costa, Max
2002 Jun;383(6):961-967, Biological chemistry
— id: 39406, year: 2002, vol: 383, page: 961, stat: Journal Article,

The role of oxidative stress in nickel and chromate genotoxicity
Costa, Max; Salnikow, Konstantin; Sutherland, Jessica E; Broday, Limor; Peng, Wu; Zhang, Qunwei; Kluz, Thomas
2002 May-Jun;234-235(1-2):265-275, Molecular & cellular biochemistry
— id: 34647, year: 2002, vol: 234-235, page: 265, stat: Journal Article,

Differential role of hydrogen peroxide in UV-induced signal transduction
Ding, Min; Li, Jingxia; Leonard, Stephen S; Shi, Xianglin; Costa, Max; Castranova, Vincent; Vallyathan, Val; Huang, Chuanshu
2002 May-Jun;234-235(1-2):81-90, Molecular & cellular biochemistry
— id: 38402, year: 2002, vol: 234-235, page: 81, stat: Journal Article,

Ultraviolet-induced phosphorylation of p70(S6K) at Thr(389) and Thr(421)/Ser(424) involves hydrogen peroxide and mammalian target of rapamycin but not Akt and atypical protein kinase C
Huang, Chuanshu; Li, Jingxia; Ke, Qingdong; Leonard, Stephen S; Jiang, Bing-Hua; Zhong, Xiao-Song; Costa, Max; Castranova, Vincent; Shi, Xianglin
2002 Oct 15;62(20):5689-5697, Cancer research
— id: 38401, year: 2002, vol: 62, page: 5689, stat: Journal Article,

Activation of nuclear factor-kappaB and not activator protein-1 in cellular response to nickel compounds
Huang, Yi; Davidson, Gerard; Li, Jingxia; Yan, Yan; Chen, Fei; Costa, Max; Chen, Lung Chi; Huang, Chuanshu
2002 Oct;110 Suppl 5(4):835-839, Environmental health perspectives
— id: 38400, year: 2002, vol: 110 Suppl 5, page: 835, stat: Journal Article,

The role of hypoxia-inducible signaling pathway in nickel carcinogenesis
Salnikow, Konstantin; Davidson, Todd; Costa, Max
2002 Oct;110 Suppl 5(2):831-834, Environmental health perspectives
— id: 34645, year: 2002, vol: 110 Suppl 5, page: 831, stat: Journal Article,

The regulation of hypoxic genes by calcium involves c-Jun/AP-1, which cooperates with hypoxia-inducible factor 1 in response to hypoxia
Salnikow, Konstantin; Kluz, Thomas; Costa, Max; Piquemal, David; Demidenko, Zoya N; Xie, Keping; Blagosklonny, Mikhail V
2002 Mar;22(6):1734-1741, Molecular & cellular biology
— id: 26987, year: 2002, vol: 22, page: 1734, stat: Journal Article,

DNA methylation and gene silencing
Sutherland JE; Costa M
Comprehensive toxicology : volume 14, Cellular and molecular toxicology New York : Elsevier, 2002,
— id: 4432, year: 2002, vol: , page: 299, stat: Chapter,

Nickel
Sutherland JE; Costa M
Heavy metals in the environment New York : Dekker, 2002,
— id: 4433, year: 2002, vol: , page: ?, stat: Chapter,

Comparison of the cytotoxicity, cellular uptake, and DNA-protein crosslinks induced by potassium chromate in lymphoblast cell lines derived from three different individuals
Zhang, Qunwei; Kluz, Thomas; Salnikow, Konstantin; Costa, Max
2002 Apr;86(1):11-22, Biological trace element research
— id: 34650, year: 2002, vol: 86, page: 11, stat: Journal Article,

Ni(II) and Cu(II) binding with a 14-aminoacid sequence of Cap43 protein, TRSRSHTSEGTRSR (vol 84, pg 47, 2001)
Zoroddu, MA; Kowalik-Jankowska, T; Kozlowski, H; Salnikow, K; Costa, M
2002 AUG 15 ;91(2):421-421, Journal of inorganic biochemistry
— id: 55290, year: 2002, vol: 91, page: 421, stat: Journal Article,

The binding of Ni(II) and Cu(II) with the N-terminal tail of the histone H4
Zoroddu, MA; Peana, M; Kowalik-Jankowska, T; Kozlowski, H; Costa, M
2002 Jan 20;18(3):458-465, Journal of the Chemical Society. Dalton transactions
— id: 28193, year: 2002, vol: 18, page: 458, stat: Journal Article,

Molecular mechanisms in nickel carcinogenesis: modeling Ni(II) binding site in histone H4
Zoroddu, Maria Antonietta; Schinocca, Laura; Kowalik-Jankowska, Teresa; Kozlowski, Henryk; Salnikow, Konstantin; Costa, Max
2002 Oct;110 Suppl 5(2):719-723, Environmental health perspectives
— id: 34646, year: 2002, vol: 110 Suppl 5, page: 719, stat: Journal Article,

Detecting epigenetic changes: DNA methylation
Broday, L; Costa, M
2001 May;Chapter 3:Unit3.6-Unit3.6 Unit3.6, Current protocols in toxicology
— id: 248762, year: 2001, vol: Chapter 3, page: Unit3.6, stat: Journal Article,

Molecular biology of nickel carcinogenesis
Costa M; Sutherland JE; Peng W; Salnikow K; Broday L; Kluz T
2001 Jun;222(1-2):205-211, Molecular & cellular biochemistry
— id: 26988, year: 2001, vol: 222, page: 205, stat: Journal Article,

Cell transformation assays
Costa, M; Sutherland, J E
2001 May;Chapter 3:Unit3.4-Unit3.4 Unit3.4, Current protocols in toxicology
— id: 248742, year: 2001, vol: Chapter 3, page: Unit3.4, stat: Journal Article,

Hydrogen peroxide mediates activation of nuclear factor of activated T cells (NFAT) by nickel subsulfide
Huang C; Li J; Costa M; Zhang Z; Leonard SS; Castranova V; Vallyathan V; Ju G; Shi X
2001 Nov 15;61(22):8051-8057, Cancer research
— id: 26560, year: 2001, vol: 61, page: 8051, stat: Journal Article,

Transactivation of RARE and GRE in the cellular response to arsenic
Huang C; Li J; Ding M; Costa M; Castranova V; Vallyathan V; Ju G; Shi X
2001 Jun;222(1-2):119-125, Molecular & cellular biochemistry
— id: 38405, year: 2001, vol: 222, page: 119, stat: Journal Article,

Arsenic-induced NFkappaB transactivation through Erks- and JNKs-dependent pathways in mouse epidermal JB6 cells
Huang C; Li J; Ding M; Wang L; Shi X; Castranova V; Vallyathan V; Ju G; Costa M
2001 Jun;222(1-2):29-34, Molecular & cellular biochemistry
— id: 38403, year: 2001, vol: 222, page: 29, stat: Journal Article,

Involvement of Erks activation in cadmium-induced AP-1 transactivation in vitro and in vivo
Huang C; Zhang Q; Li J; Shi X; Castranova V; Ju G; Costa M; Dong Z
2001 Jun;222(1-2):141-147, Molecular & cellular biochemistry
— id: 38404, year: 2001, vol: 222, page: 141, stat: Journal Article,

Mutagenesis assays in Mammalian cells
Klein, C B; Broday, L; Costa, M
2001 May;Chapter 3:Unit3.3-Unit3.3, Current protocols in toxicology
— id: 113815, year: 2001, vol: Chapter 3, page: Unit3.3, stat: Journal Article,

The histone deacetylase inhibitor trichostatin A reduces nickel-induced gene silencing in yeast and mammalian cells
Sutherland JE; Peng W; Zhang Q; Costa M
2001 Aug 8;479(1-2):225-233, Mutation research
— id: 26632, year: 2001, vol: 479, page: 225, stat: Journal Article,

Assays for DNA damage
Sutherland, J E; Costa, M
2001 May;Chapter 3:Unit3.5-Unit3.5 Unit3.5, Current protocols in toxicology
— id: 248752, year: 2001, vol: Chapter 3, page: Unit3.5, stat: Journal Article,

Ni(II) and Cu(II) binding with a 14-aminoacid sequence of Cap43 protein, TRSRSHTSEGTRSR
Zoroddu MA; Kowalik-Jankowska T; Kozlowski H; Salnikow K; Costa M
2001 Mar;84(1-2):47-54, Journal of inorganic biochemistry
— id: 34652, year: 2001, vol: 84, page: 47, stat: Journal Article,

Nickel compounds are novel inhibitors of histone H4 acetylation
Broday L; Peng W; Kuo MH; Salnikow K; Zoroddu M; Costa M
2000 Jan 15;60(2):238-241, Cancer research
— id: 11839, year: 2000, vol: 60, page: 238, stat: Journal Article,

Chromium
Cohen M; Costa M
Environmental toxicants : human exposures and their health effects New York : Wiley, 2000,
— id: 4430, year: 2000, vol: , page: 173, stat: Chapter,

Chromium
Costa M
Molecular biology and toxicology of metals New York : Taylor & Francis, 2000,
— id: 4429, year: 2000, vol: , page: 113, stat: Chapter,

Trace elements: alumninum, arsenic, cadmium, and nickel
Costa M
Environmental toxicants : human exposures and their health effects New York : Wiley, 2000,
— id: 4431, year: 2000, vol: , page: 811, stat: Chapter,

Transcriptional inactivation of genes by nickel compounds involves inhibition of histone H$ acetylation
Costa M; Salnikow K; Broday L; Peng W; Sutherland JE; Zoroddu M
2000 ;6:95-97, Metal ions in biology & medicine = Les ions metalliques en biologie et en medicine
— id: 72793, year: 2000, vol: 6, page: 95, stat: Journal Article,

Vanadate induces p53 transactivation through hydrogen peroxide and causes apoptosis
Huang C; Zhang Z; Ding M; Li J; Ye J; Leonard SS; Shen HM; Butterworth L; Lu Y; Costa M; Rojanasakul Y; Castranova V; Vallyathan V; Shi X
2000 Oct 20;275(42):32516-32522, Journal of biological chemistry
— id: 34185, year: 2000, vol: 275, page: 32516, stat: Journal Article,

Carcinogenic nickel induces genes involved with hypoxic stress
Salnikow K; Blagosklonny MV; Ryan H; Johnson R; Costa M
2000 Jan 1;60(1):38-41, Cancer research
— id: 10355, year: 2000, vol: 60, page: 38, stat: Journal Article,

Epigenetic mechanisms of nickel carcinogenesis
Salnikow K; Costa M
2000 ;19(3):307-318, Journal of environmental pathology, toxicology & oncology
— id: 10343, year: 2000, vol: 19, page: 307, stat: Journal Article,

Hyperinducibility of hypoxia-responsive genes without p53/p21-dependent checkpoint in aggressive prostate cancer
Salnikow K; Costa M; Figg WD; Blagosklonny MV
2000 Oct 15;60(20):5630-5634, Cancer research
— id: 15999, year: 2000, vol: 60, page: 5630, stat: Journal Article,

Identification of signaling pathways affected by nickel compounds
Salnikow K; Costa M; Klutz T; Zoroddu M
2000 ;6:98-100, Metal ions in biology & medicine = Les ions metalliques en biologie et en medicine
— id: 72794, year: 2000, vol: 6, page: 98, stat: Journal Article,

Carcinogenic metals induce hypoxia-inducible factor-stimulated transcription by reactive oxygen species-independent mechanism
Salnikow K; Su W; Blagosklonny MV; Costa M
2000 Jul 1;60(13):3375-3378, Cancer research
— id: 10345, year: 2000, vol: 60, page: 3375, stat: Journal Article,

Rats retain chromium in tissues following chronic ingestion of drinking water containing hexavalent chromium
Sutherland JE; Zhitkovich A; Kluz T; Costa M
2000 Apr;74(1):41-53, Biological trace element research
— id: 39531, year: 2000, vol: 74, page: 41, stat: Journal Article,

Interaction of Ni(II) and Cu(II) with metal binding sequences of histone H4
Zoroddu M; Kowalik-Jankowska T; Kozlowski H; Salnikow K; Broady L; Costa M
2000 ;6:101-103, Metal ions in biology & medicine = Les ions metalliques en biologie et en medicine
— id: 72795, year: 2000, vol: 6, page: 101, stat: Journal Article,

Interaction of Ni(II) and Cu(II) with a metal binding sequence of histone H4: AKRHRK, a model of the H4 tail
Zoroddu MA; Kowalik-Jankowska T; Kozlowski H; Molinari H; Salnikow K; Broday L; Costa M
2000 Jul 3;1475(2):163-168, Biochimica & biophysica acta
— id: 16000, year: 2000, vol: 1475, page: 163, stat: Journal Article,

Nickel enhances telomeric silencing in Saccharomyces cerevisiae
Broday L; Cai J; Costa M
1999 Apr 6;440(2):121-130, Mutation research
— id: 6096, year: 1999, vol: 440, page: 121, stat: Journal Article,

5-azacytidine induces transgene silencing by DNA methylation in Chinese hamster cells
Broday L; Lee YW; Costa M
1999 Apr;19(4):3198-3204, Molecular & cellular biology
— id: 6060, year: 1999, vol: 19, page: 3198, stat: Journal Article,

Nickel carcinogenesis, mutation, epigenetics, or selection
Costa, M; Klein, CB
1999 SEP ;107(9):A438-A439, Environmental health perspectives
— id: 53956, year: 1999, vol: 107, page: A438, stat: Journal Article,

Mutagenesis assays in mammalian cells
Klein CB; Broday L; Costa M
1999 ;1:3.3.1-3.3.7, Current protocols in toxicology
— id: 72791, year: 1999, vol: 1, page: 3.3.1, stat: Journal Article,

Nickel-induced transformation shifts the balance between HIF-1 and p53 transcription factors
Salnikow K; An WG; Melillo G; Blagosklonny MV; Costa M
1999 Sep;20(9):1819-1823, Carcinogenesis
— id: 6193, year: 1999, vol: 20, page: 1819, stat: Journal Article,

Role of Ca(2+) in the regulation of nickel-inducible Cap43 gene expression
Salnikow K; Kluz T; Costa M
1999 Oct 15;160(2):127-132, Toxicology & applied pharmacology
— id: 6223, year: 1999, vol: 160, page: 127, stat: Journal Article,

Chromium compounds
Cohen MD; Costa M
Environmental and occupational medicine Philadelphia : Lippincott-Raven, 1998,
— id: 4427, year: 1998, vol: , page: 1045, stat: Chapter,

Carcinogenic metals
Costa M
1998 ;81 ( Pt 4):329-339, Science progress
— id: 6069, year: 1998, vol: 81 ( Pt 4), page: 329, stat: Journal Article,

Molecular biology of nickel carcinogenesis
Costa, M
1998 JUN ;361(4):381-385, Fresenius journal of analytical chemistry
— id: 53384, year: 1998, vol: 361, page: 381, stat: Journal Article,

Effects of nickel on DNA methyltransferase activity and genomic DNA methylation levels
Lee YW; Broday L; Costa M
1998 Jul 31;415(3):213-218, Mutation research
— id: 7646, year: 1998, vol: 415, page: 213, stat: Journal Article,

Nickel toxicity and nickel carcinogenesis
Snow ET; Costa M
Environmental and occupational medicine Philadelphia : Lippincott-Raven, 1998,
— id: 4428, year: 1998, vol: , page: 1057, stat: Chapter,

Cr(III)-mediated crosslinks of glutathione or amino acids to the DNA phosphate backbone are mutagenic in human cells
Voitkun V; Zhitkovich A; Costa M
1998 Apr 15;26(8):2024-2030, Nucleic acids research
— id: 8085, year: 1998, vol: 26, page: 2024, stat: Journal Article,

Utilization of DNA-protein cross-links as a biomarker of chromium exposure
Zhitkovich A; Voitkun V; Kluz T; Costa M
1998 Aug;106 Suppl 4:969-974, Environmental health perspectives
— id: 7869, year: 1998, vol: 106 Suppl 4, page: 969, stat: Journal Article,

Biologic markers
Zhitkovitch A; Costa M
Environmental and occupational medicine Philadelphia : Lippincott-Raven, 1998,
— id: 4426, year: 1998, vol: , page: 177, stat: Chapter,

Cap43, a novel gene specifically induced by Ni2+ compounds
Zhou D; Salnikow K; Costa M
1998 May 15;58(10):2182-2189, Cancer research
— id: 7870, year: 1998, vol: 58, page: 2182, stat: Journal Article,

Chromatin condensation and DNA methylation during nickel carcinogenesis
Costa M
1997 ;5:359-366, Metal ions in biology & medicine = Les ions metalliques en biologie et en medicine
— id: 72782, year: 1997, vol: 5, page: 359, stat: Journal Article,

Epigenetic mechanisms of nickel carcinogenesis
Costa M
Trace elements in man and animals -- 9 Ottawa : NRC Research Press, 1997,
— id: 4424, year: 1997, vol: , page: 534, stat: Chapter,

Nonmutagenic mechanisms of nickel carcinogenesis : inactivation of critical genes by nickel-induced DNA methylation and chromatin condensation
Costa M
Correlations between in vitro and in vivo investigations in inhalation toxicology Washington DC : ILSI Press, 1997,
— id: 4423, year: 1997, vol: , page: 359, stat: Chapter,

Toxicity and carcinogenicity of Cr(VI) in animal models and humans
Costa M
1997 Sep;27(5):431-442, Critical reviews in toxicology
— id: 10361, year: 1997, vol: 27, page: 431, stat: Journal Article,

DNA-protein cross-links produced by various chemicals in cultured human lymphoma cells
Costa M; Zhitkovich A; Harris M; Paustenbach D; Gargas M
1997 Apr 11;50(5):433-449, Journal of toxicology & environmental health
— id: 12327, year: 1997, vol: 50, page: 433, stat: Journal Article,

Carcinogenic inorganic chemicals
Farrell RP; Costa M
Comprehensive toxicology New York : Pergamon Press, 1997,
— id: 4425, year: 1997, vol: 12, page: 225, stat: Chapter,

DNA methylation and gene expression: introduction and overview
Klein CB; Costa M
1997 Apr;386(2):103-105, Mutation research
— id: 12337, year: 1997, vol: 386, page: 103, stat: Journal Article,

DNA methylation, heterochromatin and epigenetic carcinogens
Klein CB; Costa M
1997 Apr;386(2):163-180, Mutation research
— id: 8210, year: 1997, vol: 386, page: 163, stat: Journal Article,

Carcinogenicity assessment of selected nickel compounds
Oller, A R; Costa, M; Oberdorster, G
1997 Mar;143(1):152-166, Toxicology & applied pharmacology
— id: 141436, year: 1997, vol: 143, page: 152, stat: Journal Article,

Induction of activating transcription factor 1 by nickel and its role as a negative regulator of thrombospondin I gene expression
Salnikow K; Wang S; Costa M
1997 Nov 15;57(22):5060-5066, Cancer research
— id: 12220, year: 1997, vol: 57, page: 5060, stat: Journal Article,

Ternary DNA adducts formed by carcinogenic Cr compounds: In vitro formation and mutagenic potential
Zhitkovich A; Voitkun V; Costa M
1997 ;38:A271-A271, Proceedings of the annual meeting of the American Association for Cancer Research
— id: 6030, year: 1997, vol: 38, page: A271, stat: Journal Article,

Carcinogenicity and genotoxicity of lead, beryllium, and other metals
Cohen MD; Bowser DH; Costa M
Toxicology of metals Boca Raton FL : Lewis Publishers, 1996,
— id: 4422, year: 1996, vol: , page: 253, stat: Chapter,

Mechanisms of nickel genotoxicity and carcinogenicity
Costa M
Toxicology of metals Boca Raton FL : Lewis Publishers, 1996,
— id: 4421, year: 1996, vol: , page: 245, stat: Chapter,

Overview : an introduction to metal toxicity and carcinogenicity of metals
Costa M
Toxicology of metals Boca Raton FL : Lewis Publishers, 1996,
— id: 4420, year: 1996, vol: , page: 203, stat: Chapter,

Interlaboratory validation of a new assay for DNA-protein crosslinks
Costa M; Zhitkovich A; Gargas M; Paustenbach D; Finley B; Kuykendall J; Billings R; Carlson TJ; Wetterhahn K; Xu J; Patierno S; Bogdanffy M
1996 Jul 10;369(1-2):13-21, Mutation research
— id: 10371, year: 1996, vol: 369, page: 13, stat: Journal Article,

Monitoring human lymphocytic DNA-protein cross-links as biomarkers of biologically active doses of chromate
Costa M; Zhitkovich A; Toniolo P; Taioli E; Popov T; Lukanova A
1996 Oct;104 Suppl 5:917-919, Environmental health perspectives
— id: 12521, year: 1996, vol: 104 Suppl 5, page: 917, stat: Journal Article,

Peroxidase deficiency of nickel-transformed hamster cells correlates with their increased resistance to cytotoxicity of peroxides
Dowjat WK; Huang X; Cosentino S; Costa M
1996 Apr;9(2):151-156, Biometals
— id: 10372, year: 1996, vol: 9, page: 151, stat: Journal Article,

Mutagenicity of cobalt and reactive oxygen producers
Kitahara J; Yamanaka K; Kato K; Lee YW; Klein CB; Costa M
1996 Oct 1;370(3-4):133-140, Mutation research
— id: 10369, year: 1996, vol: 370, page: 133, stat: Journal Article,

Occupational exposure to Cr(VI): comparison between chromium levels in lymphocytes, erythrocytes, and urine
Lukanova A; Toniolo P; Zhitkovich A; Nikolova V; Panev T; Popov T; Taioli E; Costa M
1996 ;69(1):39-44, International archives of occupational & environmental health
— id: 10374, year: 1996, vol: 69, page: 39, stat: Journal Article,

DNA-protein crosslinks as a biomarker of cis-platinum activity in cancer patients
Taioli, E; Zhitkovich, A; Toniolo, P; Bernstein, J; Blum, R; Costa, M
1996 MAY-JUN ;3(3):439-441, Oncology reports
— id: 52979, year: 1996, vol: 3, page: 439, stat: Journal Article,

Formation of the amino acid-DNA complexes by hexavalent and trivalent chromium in vitro: importance of trivalent chromium and the phosphate group
Zhitkovich A; Voitkun V; Costa M
1996 Jun 4;35(22):7275-7282, Biochemistry
— id: 7063, year: 1996, vol: 35, page: 7275, stat: Journal Article,

DNA-protein crosslinks in peripheral lymphocytes of individuals exposed to hexavalent chromium compounds
Zhitkovich, A; Lukanova, A; Popov, T; Taioli, E; Cohen, H; Costa, M; Toniolo, P
1996 APR-JUN ;1(2):86-93, Biomarkers
— id: 52703, year: 1996, vol: 1, page: 86, stat: Journal Article,

The receptor tyrosine kinase ARK mediates cell aggregation by homophilic binding
Bellosta P; Costa M; Lin DA; Basilico C
1995 Feb;15(2):614-625, Molecular & cellular biology
— id: 8207, year: 1995, vol: 15, page: 614, stat: Journal Article,

Chemical mechanisms of metal carcinogenesis
Costa M
Handbook of metal-ligand interactions in biological fluids : bioinorganic chemistry New York : Dekker, 1995,
— id: 4418, year: 1995, vol: , page: 838, stat: Chapter,

Diverse aspects of metal carcinogenesis
Costa M
Handbook of metal-ligand interactions in biological fluids : bioinorganic chemistry New York : Dekker, 1995,
— id: 4419, year: 1995, vol: , page: 1003, stat: Chapter,

Inactivation of critical cancer-related genes by nickel-induced DNA hypermethylation and increased chromatin condensation
Costa M
Genetic response to metals New York : Dekker, 1995,
— id: 4417, year: 1995, vol: , page: 53, stat: Chapter,

Model for the epigenetic mechanism of action of nongenotoxic carcinogens
Costa M
1995 Mar;61(3 Suppl):666S-669S, American journal of clinical nutrition
— id: 6596, year: 1995, vol: 61, page: 666S, stat: Journal Article,

MOLECULAR RESPONSE TO NICKEL - INHERITED EFFECTS ON TRANSCRIPTION
COSTA, M
1995 MAR 10 ;14(1-6):242-242, Journal of cellular biochemistry
— id: 86744, year: 1995, vol: 14, page: 242, stat: Journal Article,

NICKEL CARCINOGENESIS - INACTIVATION OF SENESCENCE AND OTHER CANCER-RELATED GENES BY ENHANCED HETEROCHROMATIN CONDENSATION AND DNA HYPERMETHYLATION
COSTA, M
1995 JAN 5 ;336(3):185-185, Journal of cellular biochemistry
— id: 87350, year: 1995, vol: 336, page: 185, stat: Journal Article,

INACTIVATION OF RETINOBLASTOMA PROTEIN ASSOCIATED WITH NICKEL-INDUCED TRANSFORMATION OF HUMAN-CELLS
DOWJAT, WK; LIN, X; COSTA, M
1995 JAN 5 ;336(3):195-195, Journal of cellular biochemistry
— id: 87352, year: 1995, vol: 336, page: 195, stat: Journal Article,

Unlike chromium(III) alone, low concentrations of amino acid-chromium(III)-DNA-crosslinks act as strong blocks to DNA replication
Gao M; Snow ET; Singh J; Zhitkovich A; Costa M
1995 ;25 (Suppl. 25):17-17, Environmental & molecular mutagenesis
— id: 6033, year: 1995, vol: 25 (Suppl. 25), page: 17, stat: Journal Article,

Heterochromatic proteins specifically enhance nickel-induced 8-oxo-dG formation
Huang X; Kitahara J; Zhitkovich A; Dowjat K; Costa M
1995 Aug;16(8):1753-1759, Carcinogenesis
— id: 6833, year: 1995, vol: 16, page: 1753, stat: Journal Article,

Carcinogenic nickel silences gene expression by chromatin condensation and DNA methylation: a new model for epigenetic carcinogens
Lee YW; Klein CB; Kargacin B; Salnikow K; Kitahara J; Dowjat K; Zhitkovich A; Christie NT; Costa M
1995 May;15(5):2547-2557, Molecular & cellular biology
— id: 6675, year: 1995, vol: 15, page: 2547, stat: Journal Article,

THE LOW-LEVELS OF SOME TRANSCRIPTION FACTORS BINDING IN NICKEL RESISTANT CELLS CORRELATES WITH SILENCING OF THROMBOSPONDIN EXPRESSION
SALNIKOW, K; GAO, M; WANG, S; COSTA, M
1995 JAN 5 ;336(3):190-190, Journal of cellular biochemistry
— id: 87351, year: 1995, vol: 336, page: 190, stat: Journal Article,

Increased DNA-protein crosslinks in lymphocytes of residents living in chromium-contaminated areas
Taioli E; Zhitkovich A; Kinney P; Udasin I; Toniolo P; Costa M
1995 Dec;50(3):175-180, Biological trace element research
— id: 10377, year: 1995, vol: 50, page: 175, stat: Journal Article,

NORMAL VALUES OF DNA-PROTEIN CROSS-LINKS IN MONONUCLEAR BLOOD-CELLS OF A POPULATION OF HEALTHY CONTROLS
TAIOLI, E; ZHITKOVICH, A; TONIOLO, P; COSTA, M
1995 MAR-APR ;8(2):76-79, Cancer Journal = Journal du cancer = Diario del cancer
— id: 87362, year: 1995, vol: 8, page: 76, stat: Journal Article,

Glutathione and free amino acids form stable complexes with DNA following exposure of intact mammalian cells to chromate
Zhitkovich A; Voitkun V; Costa M
1995 Apr;16(4):907-913, Carcinogenesis
— id: 6795, year: 1995, vol: 16, page: 907, stat: Journal Article,

GLUTATHIONE AND FREE AMINO-ACIDS FORM STABLE ADDUCTS WITH DNA FOLLOWING EXPOSURE OF CHO CELLS TO CHROMATE
ZHITKOVICH, A; VOITKUN, V; COSTA, M
1995 JAN 5 ;336(3):198-198, Journal of cellular biochemistry
— id: 87354, year: 1995, vol: 336, page: 198, stat: Journal Article,

The role of oxygen radicals in the nickel-induced toxicity and carcinogenicity
Costa M
Frontiers of reactive oxygen species in biology and medicine Amsterdam : Excerpta Medica, 1994,
— id: 4416, year: 1994, vol: , page: 539, stat: Chapter,

Molecular mechanisms of nickel carcinogenesis
Costa M; Salnikow K; Cosentino S; Klein CB; Huang X; Zhuang Z
1994 Sep;102 Suppl 3:127-130, Environmental health perspectives
— id: 8073, year: 1994, vol: 102 Suppl 3, page: 127, stat: Journal Article,

Molecular mechanisms of nickel carcinogenesis
Costa M; Zhuang Z; Huang X; Cosentino S; Klein CB; Salnikow K
1994 Jun 6;148(2-3):191-199, Science of the total environment
— id: 10380, year: 1994, vol: 148, page: 191, stat: Journal Article,

MOLECULAR MECHANISMS OF NICKEL CARCINOGENESIS - INHERITED EFFECTS ON TRANSCRIPTION
COSTA, M
1994 MAR 13 ;207(11):421-INOR, Abstracts of papers (American Chemical Society)
— id: 52570, year: 1994, vol: 207, page: 421, stat: Journal Article,

2ND INTERNATIONAL MEETING ON MOLECULAR MECHANISMS OF METAL TOXICITY AND CARCINOGENICITY - JANUARY 10-17, 1993 MADONNA-DI-CAMPIGLIO, ITALY - PREFACE
COSTA, M; CANTONI, O; KLEIN, C; ROSSMAN, T; SNOW, E; SUK, W
1994 SEP ;102(1):2-2, Environmental health perspectives
— id: 52335, year: 1994, vol: 102, page: 2, stat: Journal Article,

ALTERATION IN THE PHOSPHORYLATION OF THE RB PROTEIN IN NICKEL-TRANSFORMED HUMAN-CELLS
COSTA, M; DOWJAT, WK; LIN, XL
1994 FEB 13 ;15(3):194-194, Journal of cellular biochemistry
— id: 52509, year: 1994, vol: 15, page: 194, stat: Journal Article,

Second International Meeting on Molecular Mechanisms of Metal Toxicity and Carcinogenicity : January 10-17, 1993, Madonna di Campiglio, Italy
Costa, Max
Research Triangle Park, NC : National Institute of Environmental Health Sciences, 1994,
— id: 1219, year: 1994, vol: , page: , stat: ,

Crystalline Ni3S2 specifically enhances the formation of oxidants in the nuclei of CHO cells as detected by dichlorofluorescein
Huang X; Klein CB; Costa M
1994 Mar;15(3):545-548, Carcinogenesis
— id: 6409, year: 1994, vol: 15, page: 545, stat: Journal Article,

The role of nickel and nickel-mediated reactive oxygen species in the mechanism of nickel carcinogenesis
Huang X; Zhuang Z; Frenkel K; Klein CB; Costa M
1994 Sep;102 Suppl 3:281-284, Environmental health perspectives
— id: 6647, year: 1994, vol: 102 Suppl 3, page: 281, stat: Journal Article,

Metal mutagenesis in transgenic Chinese hamster cell lines
Klein CB; Kargacin B; Su L; Cosentino S; Snow ET; Costa M
1994 Sep;102 Suppl 3:63-67, Environmental health perspectives
— id: 6661, year: 1994, vol: 102 Suppl 3, page: 63, stat: Journal Article,

Transformation of human osteoblasts to anchorage-independent growth by insoluble nickel particles
Lin X; Costa M
1994 Sep;102 Suppl 3:289-292, Environmental health perspectives
— id: 6682, year: 1994, vol: 102 Suppl 3, page: 289, stat: Journal Article,

Nickel-induced transformation of human cells causes loss of the phosphorylation of the retinoblastoma protein
Lin X; Dowjat WK; Costa M
1994 May 15;54(10):2751-2754, Cancer research
— id: 6440, year: 1994, vol: 54, page: 2751, stat: Journal Article,

Loss of thrombospondin transcriptional activity in nickel-transformed cells
Salnikow K; Cosentino S; Klein C; Costa M
1994 Jan;14(1):851-858, Molecular & cellular biology
— id: 6507, year: 1994, vol: 14, page: 851, stat: Journal Article,

Altered oxidative stress responses in nickel-resistant mammalian cells
Salnikow K; Gao M; Voitkun V; Huang X; Costa M
1994 Dec 15;54(24):6407-6412, Cancer research
— id: 6738, year: 1994, vol: 54, page: 6407, stat: Journal Article,

The loss of thrombospondin expression in Ni-resistant and Ni-transformed cells
Salnikow K; Wang S; Gao M; Klein C; Costa M
1994 ;35:A1122-A1122, Proceedings of the annual meeting of the American Association for Cancer Research
— id: 6019, year: 1994, vol: 35, page: A1122, stat: Journal Article,

EFFECT OF THE RB ON THROMBOSPONDIN TRANSCRIPTION IN NORMAL AND NICKEL-TRANSFORMED CELLS
SALNIKOW, K; COSTA, M
1994 FEB 13 ;15(3):192-192, Journal of cellular biochemistry
— id: 52508, year: 1994, vol: 15, page: 192, stat: Journal Article,

Application of reliability models to studies of biomarker validation
Taioli E; Kinney P; Zhitkovich A; Fulton H; Voitkun V; Cosma G; Frenkel K; Toniolo P; Garte S; Costa M
1994 Mar;102(3):306-309, Environmental health perspectives
— id: 10381, year: 1994, vol: 102, page: 306, stat: Journal Article,

Complexing of amino acids to DNA by chromate in intact cells
Voitkun V; Zhitkovich A; Costa M
1994 Sep;102 Suppl 3:251-255, Environmental health perspectives
— id: 6768, year: 1994, vol: 102 Suppl 3, page: 251, stat: Journal Article,

Development of an 125I-postlabeling assay as a simple, rapid, and sensitive index of DNA-protein cross-links
Zhuang Z; Costa M
1994 Sep;102 Suppl 3:301-304, Environmental health perspectives
— id: 6796, year: 1994, vol: 102 Suppl 3, page: 301, stat: Journal Article,

Protein oxidation and amino acid-DNA crosslinking by nickel compounds in intact cultured cells
Zhuang Z; Huang X; Costa M
1994 Jun;126(2):319-325, Toxicology & applied pharmacology
— id: 6563, year: 1994, vol: 126, page: 319, stat: Journal Article,

Mechanisms of chromium carcinogenicity and toxicity
Cohen MD; Kargacin B; Klein CB; Costa M
1993 ;23(3):255-281, Critical reviews in toxicology
— id: 6337, year: 1993, vol: 23, page: 255, stat: Journal Article,

Molecular targets of nickel and chromium in human and experimental systems
Costa M
1993 ;19 Suppl 1:71-74, Scandinavian journal of work environment & health
— id: 6342, year: 1993, vol: 19 Suppl 1, page: 71, stat: Journal Article,

Preliminary report on a simple new assay for DNA-protein cross-links as a biomarker of exposures experienced by welders
Costa M; Zhitkovich A; Taioli E; Toniolo P
1993 Oct-Nov;40(2-3):217-222, Journal of toxicology & environmental health
— id: 6343, year: 1993, vol: 40, page: 217, stat: Journal Article,

DNA-protein cross-links in welders: molecular implications
Costa M; Zhitkovich A; Toniolo P
1993 Feb 1;53(3):460-463, Cancer research
— id: 10386, year: 1993, vol: 53, page: 460, stat: Journal Article,

Nickel induces increased oxidants in intact cultured mammalian cells as detected by dichlorofluorescein fluorescence
Huang X; Frenkel K; Klein CB; Costa M
1993 May;120(1):29-36, Toxicology & applied pharmacology
— id: 10384, year: 1993, vol: 120, page: 29, stat: Journal Article,

Mutagenic responses of nickel oxides and nickel sulfides in Chinese hamster V79 cell lines at the xanthine-guanine phosphoribosyl transferase locus
Kargacin B; Klein CB; Costa M
1993 Jun;300(1):63-72, Mutation research
— id: 10383, year: 1993, vol: 300, page: 63, stat: Journal Article,

COMPARISON OF THE UPTAKE AND DISTRIBUTION OF CHROMATE IN RATS AND MICE
KARGACIN, B; SQUIBB, KS; COSENTINO, S; ZHITKOVICH, A; COSTA, M
1993 MAR ;36(3):307-318, Biological trace element research
— id: 54334, year: 1993, vol: 36, page: 307, stat: Journal Article,

Development and utilization of a new simple assay for DNA-protein crosslinks as a biomarker of exposure to welding fumes
Toniolo P; Zhitkovich A; Costa M
1993 ;65(1 Suppl):S87-S89, International archives of occupational & environmental health
— id: 6540, year: 1993, vol: 65, page: S87, stat: Journal Article,

Trace elements : alumninum, arsenic, cadmium, mercury and nickel
Bhamra RK; Costa M
Environmental toxicants : human exposures and their health effects New York : Van Nostrand Reinhold, 1992,
— id: 4412, year: 1992, vol: , page: 575, stat: Chapter,

Chromium compounds
Cohen MD; Costa M
Environmental and occupational medicine Boston : Little Brown, 1992,
— id: 4413, year: 1992, vol: , page: 799, stat: Chapter,

Forward mutations and DNA-protein crosslinks induced by ammonium metavanadate in cultured mammalian cells
Cohen MD; Klein CB; Costa M
1992 Sep;269(1):141-148, Mutation research
— id: 13468, year: 1992, vol: 269, page: 141, stat: Journal Article,

Deletion of a senescence gene as a mechanism of nickel carcinogenesis
Costa M
1992 ;4(Special Supplement):481-485, Chemical speciation & bioavailability
— id: 72790, year: 1992, vol: 4, page: 481, stat: Journal Article,

Involvement of heterochromatin damage in nickel-induced transformation and resistance
Costa M; Conway K; Imbra R; Wang XW
Nickel and human health : current perspectives New York : Wiley, 1992,
— id: 4415, year: 1992, vol: , page: 295, stat: Chapter,

Analysis of residual amino acid--DNA crosslinks induced in intact cells by nickel and chromium compounds
Lin X; Zhuang Z; Costa M
1992 Oct;13(10):1763-1768, Carcinogenesis
— id: 10393, year: 1992, vol: 13, page: 1763, stat: Journal Article,

Analysis of the binding sites of chromium to DNA and protein in vitro and in intact cells
Salnikow K; Zhitkovich A; Costa M
1992 Dec;13(12):2341-2346, Carcinogenesis
— id: 10392, year: 1992, vol: 13, page: 2341, stat: Journal Article,

Nickel and nickel carcinogenesis
Snow ET; Costa M
Environmental and occupational medicine Boston : Little Brown, 1992,
— id: 4414, year: 1992, vol: , page: 807, stat: Chapter,

POTENTIATION OF SODIUM CHROMATE(VI)-INDUCED CHROMOSOMAL-ABERRATIONS AND MUTATION BY VITAMIN-B2 IN CHINESE-HAMSTER V79-CELLS
SUGIYAMA, M; TSUZUKI, K; LIN, XH; COSTA, M
1992 NOV ;283(3):211-214, Mutation research. DNA repair
— id: 51832, year: 1992, vol: 283, page: 211, stat: Journal Article,

A conserved region in human and Chinese hamster X chromosomes can induce cellular senescence of nickel-transformed Chinese hamster cell lines
Wang XW; Lin X; Klein CB; Bhamra RK; Lee YW; Costa M
1992 Apr;13(4):555-561, Carcinogenesis
— id: 13643, year: 1992, vol: 13, page: 555, stat: Journal Article,

A simple, sensitive assay to detect DNA-protein crosslinks in intact cells and in vivo
Zhitkovich A; Costa M
1992 Aug;13(8):1485-1489, Carcinogenesis
— id: 8420, year: 1992, vol: 13, page: 1485, stat: Journal Article,

Alteration in restriction enzyme digestion patterns detects DNA--protein complexes induced by chromate
Chen Y; Cohen MD; Snow ET; Costa M
1991 Sep;12(9):1575-1580, Carcinogenesis
— id: 13934, year: 1991, vol: 12, page: 1575, stat: Journal Article,

Differential DNA-protein crosslinking in lymphocytes and liver following chronic drinking water exposure of rats to potassium chromate
Coogan TP; Motz J; Snyder CA; Squibb KS; Costa M
1991 Jun 1;109(1):60-72, Toxicology & applied pharmacology
— id: 14000, year: 1991, vol: 109, page: 60, stat: Journal Article,

Distribution of chromium within cells of the blood
Coogan TP; Squibb KS; Motz J; Kinney PL; Costa M
1991 Mar 15;108(1):157-166, Toxicology & applied pharmacology
— id: 14097, year: 1991, vol: 108, page: 157, stat: Journal Article,

DNA-protein complexes induced by chromate and other carcinogens
Costa M
1991 May;92:45-52, Environmental health perspectives
— id: 14041, year: 1991, vol: 92, page: 45, stat: Journal Article,

Molecular mechanisms of nickel carcinogenesis
Costa M
1991 ;31:321-337, Annual review of pharmacology & toxicology
— id: 14156, year: 1991, vol: 31, page: 321, stat: Journal Article,

DNA damage by mercury compounds : an overview
Costa M; Christie NT; Cantoni O; Zelikoff JT; Wang XW; Rossman TG
Advances in mercury toxicology New York : Plenum Press, 1991,
— id: 4397, year: 1991, vol: , page: ?, stat: Chapter,

Senescence of nickel-transformed cells by an X chromosome: possible epigenetic control
Klein CB; Conway K; Wang XW; Bhamra RK; Lin XH; Cohen MD; Annab L; Barrett JC; Costa M
1991 Feb 15;251(4995):796-799, Science
— id: 8211, year: 1991, vol: 251, page: 796, stat: Journal Article,

The role of oxidative processes in metal carcinogenesis
Klein CB; Frenkel K; Costa M
1991 Nov-Dec;4(6):592-604, Chemical research in toxicology
— id: 13852, year: 1991, vol: 4, page: 592, stat: Journal Article,

DIFFERENCES IN THE EFFECT OF VITAMIN-E ON NICKEL SULFIDE OR NICKEL CHLORIDE-INDUCED CHROMOSOMAL-ABERRATIONS IN MAMMALIAN- CELLS
Lin, XH; Sugiyama, M; Costa, M
1991 Jun;260(2):159-164, Mutation research. DNA repair
— id: 32170, year: 1991, vol: 260, page: 159, stat: Journal Article,

Complexing of actin and other nuclear proteins to DNA by cis-diamminedichloroplatinum(II) and chromium compounds
Miller CA 3d; Cohen MD; Costa M
1991 Feb;12(2):269-276, Carcinogenesis
— id: 14136, year: 1991, vol: 12, page: 269, stat: Journal Article,

PROTECTIVE EFFECT OF VITAMIN-E AGAINST CHROMOSOMAL-ABERRATIONS AND MUTATION INDUCED BY SODIUM CHROMATE IN CHINESE-HAMSTER V79 CELLS
Sugiyama, M; Lin, XH; Costa, M
1991 May;260(1):19-23, Mutation research. DNA repair
— id: 32181, year: 1991, vol: 260, page: 19, stat: Journal Article,

Changes in protein phosphorylation in wild-type and nickel-resistant cells and their involvement in morphological elongation
Wang XW; Costa M
1991 ;4(4):201-206, Biology of metals
— id: 14236, year: 1991, vol: 4, page: 201, stat: Journal Article,

A blotting method for monitoring the formation of chemically induced DNA-protein complexes
Cohen MD; Miller CA; Xu LS; Snow ET; Costa M
1990 Apr;186(1):1-7, Analytical biochemistry
— id: 36437, year: 1990, vol: 186, page: 1, stat: Journal Article,

The detection of DNA-protein complexes in vitro by an immunological assay
Cosma, G N; Miller, C A 3rd; Costa, M
1990 ;4(1):17-22, Toxicology in vitro
— id: 111599, year: 1990, vol: 4, page: 17, stat: Journal Article,

Analysis of DNA-protein complexes induced by chemical carcinogens
Costa M
1990 Nov;44(3):127-135, Journal of cellular biochemistry
— id: 14311, year: 1990, vol: 44, page: 127, stat: Journal Article,

DELETION OF A SENESCENCE TUMOR SUPPRESSOR GENE AS A MECHANISM OF NICKEL CARCINOGENESIS
Costa, M
1990 Apr 22;199(3):25CHAS-, Abstracts of papers (American Chemical Society)
— id: 31950, year: 1990, vol: 199, page: 25CHAS, stat: Journal Article,

IMMUNODETECTION OF DNA PROTEIN CROSS-LINKS BY SLOT BLOTTING
Miller, CA; Costa, M
1990 Apr;234(2):97-106, Mutation research. DNA repair
— id: 32089, year: 1990, vol: 234, page: 97, stat: Journal Article,

Nonrandom chromosomal alterations in nickel-transformed Chinese hamster embryo cells
Conway K; Costa M
1989 Nov 1;49(21):6032-6038, Cancer research
— id: 10435, year: 1989, vol: 49, page: 6032, stat: Journal Article,

The involvement of heterochromatic damage in nickel-induced transformation
Conway K; Costa M
1989 Jul-Sep;21:437-444, Biological trace element research
— id: 10576, year: 1989, vol: 21, page: 437, stat: Journal Article,

Toxicity and carcinogenicity of nickel compounds [published erratum appears in Crit Rev Toxicol 1989;20(2):135]
Coogan TP; Latta DM; Snow ET; Costa M
1989 ;19(4):341-384, Critical reviews in toxicology
— id: 10790, year: 1989, vol: 19, page: 341, stat: Journal Article,

Perspectives on the mechanism of nickel carcinogenesis gained from models of in vitro carcinogenesis
Costa M
1989 May;81:73-76, Environmental health perspectives
— id: 10647, year: 1989, vol: 81, page: 73, stat: Journal Article,

Proceedings of the First International Meeting on Molecular Mechanisms of Metal Toxicity and Carcinogensis, hedl Sept 19-22, 1988 in Urbino, Italy
Costa, Max; Rossman, Toby
Clifton NJ : Humana Press, 1989,
— id: 1218, year: 1989, vol: , page: , stat: ,

Characterization of a nickel resistant mouse cell line
Imbra RJ; Wang XW; Costa M
1989 Jul-Sep;21:97-103, Biological trace element research
— id: 10574, year: 1989, vol: 21, page: 97, stat: Journal Article,

STUDIES ON THE MECHANISM OF NICKEL-INDUCED HETEROCHROMATIN DAMAGE - EFFECT ON SPECIFIC DNA-PROTEIN INTERACTIONS
Imbra, RJ; Latta, DM; Costa, M
1989 Oct;22(1-4):167-179, Toxicological & environmental chemistry
— id: 31617, year: 1989, vol: 22, page: 167, stat: Journal Article,

Analysis of proteins cross-linked to DNA after treatment of cells with formaldehyde, chromate, and cis-diamminedichloroplatinum(II)
Miller CA 3d; Costa M
1989 Winter;2(1):11-26, Molecular toxicology
— id: 10811, year: 1989, vol: 2, page: 11, stat: Journal Article,

Immunological detection of DNA-protein complexes induced by chromate
Miller CA 3d; Costa M
1989 Apr;10(4):667-672, Carcinogenesis
— id: 10687, year: 1989, vol: 10, page: 667, stat: Journal Article,

THE PROCEEDINGS OF THE 1ST INTERNATIONAL MEETING ON MOLECULAR MECHANISMS OF METAL TOXICITY AND CARCINOGENICITY, HELD SE
ROSSMAN, TG; COSTA, M
1989 ;21(1-4):R1-R2, Biological trace element research
— id: 104619, year: 1989, vol: 21, page: R1, stat: Journal Article,

Alteration of nickel-binding proteins in nickel-resistant cells
Wang XW; Costa M
1989 ;1(6):351-358, Cancer communications
— id: 10778, year: 1989, vol: 1, page: 351, stat: Journal Article,

Chromosomal alterations in cell lines derived from mouse rhabdomyosarcomas induced by crystalline nickel sulfide
Christie NT; Sen P; Costa M
1988 ;1(1):43-50, Biology of metals
— id: 11256, year: 1988, vol: 1, page: 43, stat: Journal Article,

TRANSFORMATION OF CHINESE-HAMSTER EMBRYO CELLS BY NICKEL YIELDS CELL-LINES WITH ALTERED HETEROCHROMATIC STAINING PATTERNS
Conway, K; Costa, M
1988 Mar;29(5):117-117, Proceedings (American Association for Cancer Research)
— id: 31480, year: 1988, vol: 29, page: 117, stat: Journal Article,

EFFECT OF NICKEL(II) ON DNA-PROTEIN INTERACTIONS
Coogan, TP; Latta, DM; Imbra, RJ; Costa, M
1988 Mar;29(5):87-87, Proceedings (American Association for Cancer Research)
— id: 31478, year: 1988, vol: 29, page: 87, stat: Journal Article,

The role of trace metals in carcinogenesis
Costa, Max; Creasey, William A
[Bethesda MD] : US Dept of Health and Human Services. International Cancer Research Data Bank, 1988,
— id: 1217, year: 1988, vol: , page: , stat: ,

Characterization of DNA-protein complexes induced in intact cells by the carcinogen chromate
Miller CA 3d; Costa M
1988 ;1(2):125-133, Molecular carcinogenesis
— id: 11257, year: 1988, vol: 1, page: 125, stat: Journal Article,

CHANGES IN NUCLEAR PROTEIN-DNA INTERACTION CAUSED BY POTASSIUM CHROMATE
MILLER, CA; COSTA, M
1988 MAR ;29(3-4):112-112, Proceedings (American Association for Cancer Research)
— id: 98523, year: 1988, vol: 29, page: 112, stat: Journal Article,

Stimulation of polyadenosine diphosphoribose synthesis by DNA lesions induced by sodium chromate in Chinese hamster V-79 cells
Sugiyama, M; Costa, M; Nakagawa, T; Hidaka, T; Ogura, R
1988 Mar 1;48(5):1100-1104, Cancer research
— id: 141422, year: 1988, vol: 48, page: 1100, stat: Journal Article,

Characterization of mouse cell lines resistant to nickel(II) ions
Wang XW; Imbra RJ; Costa M
1988 Dec 1;48(23):6850-6854, Cancer research
— id: 10871, year: 1988, vol: 48, page: 6850, stat: Journal Article,

Genetic toxicology of lead compounds
Zelikoff JT; Li JH; Hartwig A; Wang XW; Costa M; Rossman TG
1988 Oct;9(10):1727-1732, Carcinogenesis
— id: 10946, year: 1988, vol: 9, page: 1727, stat: Journal Article,

Effect of magnesium on nickel-induced genotoxicity and cell transformation
Conway, K; Wang, X W; Xu, L S; Costa, M
1987 Aug;8(8):1115-1121, Carcinogenesis
— id: 141423, year: 1987, vol: 8, page: 1115, stat: Journal Article,

Principles of industrial toxicology
Costa, M
1987 Jul;4(3):559-570, Clinics in podiatric medicine & surgery
— id: 111579, year: 1987, vol: 4, page: 559, stat: Journal Article,

EFFECTS OF CHROMATE AND NICKEL ON DNA-PROTEIN INTERACTIONS
Costa, M; Imbra, RJ; Miller, CA; Ashkenazikimmel, T; Latta, DM
1987 Mar;28(3):89-89, Proceedings (American Association for Cancer Research)
— id: 31214, year: 1987, vol: 28, page: 89, stat: Journal Article,

Effects of nickel(II) on nuclear protein binding to DNA in intact mammalian cells
Patierno, S R; Costa, M
1987 May;9(2):113-126, Cancer biochemistry biophysics
— id: 141426, year: 1987, vol: 9, page: 113, stat: Journal Article,

Effect of nickel(II) on DNA-protein binding, thymidine incorporation, and sedimentation pattern of chromatin fractions from intact mammalian cells
Patierno, S R; Sugiyama, M; Costa, M
1987 Spring;2:13-23, Journal of biochemical toxicology
— id: 141427, year: 1987, vol: 2, page: 13, stat: Journal Article,

Comparison of the localization of chromosome damage induced by calcium chromate and nickel compounds
Sen, P; Conway, K; Costa, M
1987 Apr 15;47(8):2142-2147, Cancer research
— id: 141424, year: 1987, vol: 47, page: 2142, stat: Journal Article,

Physicochemical characteristics and biological effects of nickel oxides
Sunderman, F W Jr; Hopfer, S M; Knight, J A; McCully, K S; Cecutti, A G; Thornhill, P G; Conway, K; Miller, C; Patierno, S R; Costa, M
1987 Feb;8(2):305-313, Carcinogenesis
— id: 141425, year: 1987, vol: 8, page: 305, stat: Journal Article,

Assessment of the uptake and mutagenicity of nickel chloride in salmonella tester strains
Biggart, N W; Costa, M
1986 Dec;175(4):209-215, Mutation research
— id: 141434, year: 1986, vol: 175, page: 209, stat: Journal Article,

Differences in the effects of Hg(II) on DNA repair induced in Chinese hamster ovary cells by ultraviolet or X-rays
Christie, N T; Cantoni, O; Sugiyama, M; Cattabeni, F; Costa, M
1986 Feb;29(2):173-178, Molecular pharmacology
— id: 133270, year: 1986, vol: 29, page: 173, stat: Journal Article,

Antagonistic effect of magnesium chloride on the nickel chloride-induced inhibition of DNA replication in Chinese hamster ovary cells
Conway, K; Sen, P; Costa, M
1986 Jun;1(2):11-25, Journal of biochemical toxicology
— id: 133266, year: 1986, vol: 1, page: 11, stat: Journal Article,

Metal ion carcinogenesis: mechanistic aspects
Costa M; Heck JD
1986 ;20:259-278, Metal ions in biological systems
— id: 72788, year: 1986, vol: 20, page: 259, stat: Journal Article,

Methods for the in vitro assessment of metal ion toxicity
Heck JD; Costa M
1986 ;20:279-303, Metal ions in biological systems
— id: 72789, year: 1986, vol: 20, page: 279, stat: Journal Article,

Pathway of nickel uptake influences its interaction with heterochromatic DNA
Sen, P; Costa, M
1986 Jun 30;84(2):278-285, Toxicology & applied pharmacology
— id: 133269, year: 1986, vol: 84, page: 278, stat: Journal Article,

Characterization of DNA lesions induced by CaCrO4 in synchronous and asynchronous cultured mammalian cells
Sugiyama, M; Patierno, S R; Cantoni, O; Costa, M
1986 Jun;29(6):606-613, Molecular pharmacology
— id: 141428, year: 1986, vol: 29, page: 606, stat: Journal Article,

Comparison of DNA lesions and cytotoxicity induced by calcium chromate in human, mouse, and hamster cell lines
Sugiyama, M; Wang, X W; Costa, M
1986 Sep;46(9):4547-4551, Cancer research
— id: 133267, year: 1986, vol: 46, page: 4547, stat: Journal Article,

DNA-protein cross-links induced by nickel compounds in intact cultured mammalian cells
Patierno, S R; Costa, M
1985 Oct;55(1-2):75-91, Chemico-biological interactions
— id: 141430, year: 1985, vol: 55, page: 75, stat: Journal Article,

Preferential DNA-protein cross-linking by NiCl2 in magnesium-insoluble regions of fractionated Chinese hamster ovary cell chromatin
Patierno, S R; Sugiyama, M; Basilion, J P; Costa, M
1985 Nov;45(11 Pt 2):5787-5794, Cancer research
— id: 141429, year: 1985, vol: 45, page: 5787, stat: Journal Article,

Perspectives on the mechanism of nickel carcinogenesis
Costa M; Heck JD
1984 ;6:285-309, Advances in inorganic biochemistry
— id: 72787, year: 1984, vol: 6, page: 285, stat: Journal Article,

Toxicity and carcinogenicity of essential and non-essential metals
Costa M; Kraker AJ; Patierno SR
1984 ;1:1-49, Progress in clinical biochemistry & medicine
— id: 72786, year: 1984, vol: 1, page: 1, stat: Journal Article,

Growth inhibition and metallothionein induction in cadmium-resistant cells by essential and non-essential metals
Evans, R M; Patierno, S R; Wang, D S; Cantoni, O; Costa, M
1983 Jul;24(1):77-83, Molecular pharmacology
— id: 141431, year: 1983, vol: 24, page: 77, stat: Journal Article,

Inhibition of LPS toxicity for macrophages by metallothionein-inducing agents
Patierno, S R; Costa, M; Lewis, V M; Peavy, D L
1983 Apr;130(4):1924-1929, Journal of immunology
— id: 141433, year: 1983, vol: 130, page: 1924, stat: Journal Article,

Application of a modified 203Hg binding assay for metallothionein
Patierno, S R; Pellis, N R; Evans, R M; Costa, M
1983 Apr 4;32(14):1629-1636, Life sciences
— id: 141432, year: 1983, vol: 32, page: 1629, stat: Journal Article,

Comparison of protein, RNA, and DNA binding and cell-cycle-specific growth inhibitory effects of nickel compounds in cultured cells
Harnett, P B; Robison, S H; Swartzendruber, D E; Costa, M
1982 Jun 15;64(1):20-30, Toxicology & applied pharmacology
— id: 141437, year: 1982, vol: 64, page: 20, stat: Journal Article,

Factors influencing the phagocytosis, neoplastic transformation, and cytotoxicity of particulate nickel compounds in tissue culture systems
Costa, M; Abbracchio, M P; Simmons-Hansen, J
1981 Sep 15;60(2):313-323, Toxicology & applied pharmacology
— id: 141438, year: 1981, vol: 60, page: 313, stat: Journal Article,

Biochemical and morphological transformation of hamster embryo cells in tissue culture by specific metal compounds
Costa M
Molecular basis of environmental toxicity Ann Arbor MI : Ann Arbor Science, 1980,
— id: 4410, year: 1980, vol: , page: 373, stat: Chapter,