Featured Publications:
The Cdc14B-Cdh1-Plk1 axis controls the G2 DNA damage response checkpoint
F. Bassermann, D. Frescas, D. Guardavaccaro, L. Busino, A. Peschiaroli, M. Pagano
Cell, 134:256-267, 2008.
Control of chromosome stability by the βTRCP-REST-MAD2 axis
D. Guardavaccaro, D. Frescas, N. Dorrello, A. Peschiaroli, A. Multani, T. Cardozo, A. Lasorella, A. Iavarone, S. Chang, E. Hernando, and M. Pagano.
Nature, 452, 365-369, 2008.
The histone demethylase
JHDM1B/FBXL10 is a nucleolar protein that represses
transcription of ribosomal RNA genes.
D. Frescas, D. Guardavaccaro, F.
Bassermann, R. Koyama-Nasu and M. Pagano
Nature, 450, 309-313, 2007.
SCF-Fbxl3 Controls the Oscillation of the
Circadian Clock by Directing the Degradation of Cryptochrome
Proteins.
L. Busino, F.
Bassermann, A. Maiolica, C. Lee, S. Godinho, P. Nolan, G. Draetta
and M. Pagano
Science, 316:900-904, 2007.
APC/CCdc20 controls
the ubiquitin-mediated degradation of p21 in prometaphase
V. Amador, S. Ge, P.G.
Santamaria, D. Guardavaccaro and M. Pagano
Mol Cell, 27,
462–473, 2007.
S6K1- and βTRCP-mediated
degradation of PDCD4 promotes protein translation and cell
growth.
N. V. Dorrello, A. Peschiaroli, D.
Guardavaccaro, N. H. Colburn, N. E. Sherman and M. Pagano
Science, 314:467-471, 2006.
SCFβTRCP-mediated degradation of Claspin
regulates recovery from the DNA replication checkpoint response.
A.
Peschiaroli, N. V. Dorrello, D. Guardavaccaro, M. Venere,
T. Halazonetis, N. Sherman and M. Pagano.
Mol Cell, 23: 319-329, 2006
Stabilizers and destabilizers controlling cell cycle oscillators.
D. Guardavaccaro and M. Pagano.
Mol Cell, 22:1-4 2006.
