Schwannomas
These benign nerve sheath tumors arise from the supportive tissue within the nerve itself, causing pain, weakness, and numbness.
Solitary Neurofibromas
These benign nerve sheath tumors arise from the supportive tissue within the nerve itself, resulting in pain, weakness, and numbness.
Lipomas Involving Nerves
Lipomas arise from benign fat tissue can can grow near or surrounding important peripheral nerves.
Synovial Cysts
Synovial cysts commonly communicate with nearby joints and may enlarge when joint pressure increases with movement or weight bearing.
Plexiform Neurofibromas
These extensive nerve sheath tumors generally occur in patients with neurofibromatosis type 1, and present as large soft tissue masses under the skin.
Malignant Nerve Sheath Tumors
These cancerous lesions arise from the connective tissue of peripheral nerves, occurring spontaneously, in patients with neurofibromatosis, or following radiation therapy.
Neurofibromatosis
This genetic disorder causes tumors to occur on nerves throughout the body.
Schwannomatosis
This disease is characterized by schwannomas on multiple nerves throughout the body, usually in the spine, neck, and limbs.
Metastatic and Infiltrative Tumors Involving Nerves
Direct tumor spread may invade and damage important nerves in the neck, axilla, and pelvis, causing numbness, weakness, and pain to shoot down the arm or leg.
Malignant Peripheral Nerve Sheath Tumors (MPNSTs)
These aggressive tumors arise from peripheral nerves, occuring spontaneously, but also arising from known neurofibromas in patients with neurofibromatosis.
Radiation Plexitis
Although increasingly rare, radiation therapy may cause damage to nerves, causing patients to develop numbness, sometimes followed by weakness, in the involved extremity.