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Probably one of the last frontiers
of clinical MRI, imaging of the lungs has long been considered a significant
challenge with MR because of the predominance of air within the lungs
and associated susceptibility issues as well as low intrinsic signal to
noise of the inflated lung parenchyma. Nevertheless, new imaging technologies
are opening the doors to lung MR imaging in exciting ways that may ultimately
to prove to have tremendous research and clinical impact. Among these
technologies are the use of hyperpolarized helium for use as an inert
inhalational contrast agent for studying lung ventilation properties and
the use of MRI to study lung perfusion, whether for diseases such as pulmonary
embolism or to characterize lung and mediastinal tumors.
Hyperpolarized Helium MR of the Lungs
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