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The urachus is a vestigial structure, representing the remnant
of the embryonic allantois and cloaca. In fetal life, the allantois
connects the urogential sinus with the umbilicus. Normally, the
allantois is obliterated during development and is replaced by a
fibrous cord known as the urachus. The urachus persists as a midline
structure that extends from the bladder dome to the umbilicus and
is called the median umbilical ligament.
Failure of normal closure of the urachus results in a variety of
urachal abnormalities. These include a patent urachus resulting
from complete failure closure; a urachal sinus (which drains
to the umbilicus) resulting from partial failure of closure; a urachal
cyst resulting from failure of closure of the urachus near the
bladder attachment; or an umbilical cyst resulting from failure
of closure at the umbilical attachment.
A patent urachus commonly presents with urine draining from the
umbilicus. A urachal sinus may present as a draining umbilical sinus.
Urachal cysts and diverticula are usually clinically silent and
often present during adulthood as incidental findings or because
of infection, stones, or adenocarcinoma. Neoplastic involvement
of the urachus is rare but it can extend anywhere along the course
of the urachus. Urachal tumors arise most commonly from the umbilical
segment (90%). Urachal tumors have a poor prognosis since they are
usually advanced at presentation. Mucin-producing adenocarcinomas
account for the majority of urachal tumors and occur secondary to
metaplasia of transitional epithelium lining the urachus. The remainder
of urachal tumors include clear cell carcinoma, transitional cell
carcinomas, and urachal sarcomas.
References:
- Dunnick, N Reed. Textbook of Uroradiology, 3rd Edition.
Philadelphia: Lippincott Williams & Wilkins, 2001.
- Semelka, Richard. Abdominal-Pelvic MRI. New York:
Wiley-Liss Inc, 2002.
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