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Musculoskeletal Research Center
| Project | Status | Investigator/ Contact Information |
|---|---|---|
| TIE-2 Chimeric Proteins for Inflammatory Arthritis | Upcoming | Sally Frenkel, Ph.D. |
| Anti-angionenic Local Therapy for Inflammatory Arthritis | Upcoming | Sally Frenkel, Ph.D. |
| Evaluation of Novel Polymers for Cartilage in Nude Rats | Upcoming | Sally Frenkel, Ph.D. |
| FGF-9 in Cartilage Repair | Upcoming | Sally Frenkel, Ph.D. |
| Enhancement of Bone Formation with Statins | Upcoming | Sally Frenkel, Ph.D. | Spine Fusion Enhancement with BMP-2 with Plasmid Gene Therapy in DBX | In Progress | Sally Frenkel, Ph.D. |
| Reversal of Arthritic Degeneration - Screening of Potential Therapeutic Compounds in a Rabbit Model | In Progress | Sally Frenkel, Ph.D. |
| In Vivo Comparison of Three Types of Osteochondral Allografts | In Progress | Sally Frenkel, Ph.D. |
| Is Raloxifene Chondroprotective? | In Progress | Sally Frenkel, Ph.D. |
| Gene Therapy for Articular Cartilage Repair: Naked DNA in a Tissue-Engineered Allograft DBX Device | In Progress | Sally Frenkel, Ph.D. |
| Estrogen: Chondroprotective or Destructive? | In Progress | Sally Frenkel, Ph.D. |
| Demineralized Bone Allograft for Cartilage Repair in a Large Animal Model | In Progress | Sally Frenkel, Ph.D. |
| Design and Evaluation of a Functionally Specific Three Dimensional Polymer Implant for Articular Cartilage Repair and Regeneration | In Progress | Sally Frenkel, Ph.D. | Antitumor Actions of Interferon-inducible Proteins | In Progress | Chuan-ju Liu, Ph.D. |
| Role of Interferon-inducible Proteins in Osteogenesis | In Progress | Chuan-ju Liu, Ph.D. |
| Interferon-inducible IFI16 Protein in Autoimmunodiseases | In Progress | Chuan-ju Liu, Ph.D. |
| Regulation of Chondrocyte Differentiation and Function by Growth Factors | In Progress | Chuan-ju Liu, Ph.D. |
| Molecular Control of Chondrogenesis | In Progress | Chuan-ju Liu, Ph.D. |
| Control of Skeletogenesis by MicroRNA | In Progress | Chuan-ju Liu, Ph.D. |
| Isolation of Antagomir for Treating Musculoskeletal TumorsProteomics of Chondrosarcoma | In Progress | Chuan-ju Liu, Ph.D. |
| Proteomics of Chondrosarcoma | In Progress | Chuan-ju Liu, Ph.D. |
| RbBP4 Is a Critical Mediator in Tumorgenesis | In Progress | Chuan-ju Liu, Ph.D. |
| Expression Profiling of ADAMTS in Musculoskeletal Tumors | In Progress | Chuan-ju Liu, Ph.D. |
| Regulation of ADAMTS by Cytokines and Growth Factors | In Progress | Chuan-ju Liu, Ph.D. |
| Role of ADAMTS in Cartilage Metabolism and Arthritis | In Progress | Chuan-ju Liu, Ph.D. |
| Expression, Regulation, and Function of ECM1 in Skeletal Development | In Progress | Chuan-ju Liu, Ph.D. |
| MicroRNA as a Biomarker for Detecting Osteosarcoma | In Progress | Chuan-ju Liu, Ph.D. |
| Naked DNA Gene Therapy for Cartilage Repair | In Progress | Chuan-ju Liu, Ph.D. |
| Generation of a Tissue-Specific Knock-Down Mice Model of p204 | In Progress | Chuan-ju Liu, Ph.D. |
| Curvature of the Femur and IM Nail Insertion - EBI proposal | Upcoming | Frederick J. Kummer, Ph.D. |
| Trochanteric Attachment - Smith & Nephew proposal | Upcoming | Frederick J. Kummer, Ph.D. |
| Periprosthetic Fracture Fixation | In Progress | Frederick J. Kummer, Ph.D. |
| Effects of Stem and Cement Parameters on Fixation (Several studies) | In Progress | Frederick J. Kummer, Ph.D. |
| Evaluation of Spatial Frame Configurations | In Progress | Frederick J. Kummer, Ph.D. |
| Evaluation of Prodisc | In Progress | Frederick J. Kummer, Ph.D. |
| Effects of ACL Attachment-Screw Type | In Progress | Frederick J. Kummer, Ph.D. |
| Effects of ACL Attachment-Tunnel Size | In Progress | Frederick J. Kummer, Ph.D. |
| Evaluation of Spacer Constructs | In Progress | Frederick J. Kummer, Ph.D. |
| Evaluation of Meniscal Attachment | In Progress | Frederick J. Kummer, Ph.D. |
| Rotator Interval Plication | In Progress | Frederick J. Kummer, Ph.D. |
| Scorpio Deep-Knee Flexion Analysis | In Progress | Frederick J. Kummer, Ph.D. |
| Metacarpal Fixation Methods | In Progress | Frederick J. Kummer, Ph.D. |
| Scaphoid Fixation Methods | In Progress | Frederick J. Kummer, Ph.D. |
| Surface guided knee replacement for normal motion | In Progress | Peter S Walker PhD |
| Effect of different bands of ACL on knee kinematics | In Progress | Peter S Walker PhD |
| Enhanced rehabilitation after TKR surgery using Tekscan | In Progress | Peter S Walker PhD |
| Design of CAS for TKR using Instrumented Linkage | In Progress | Peter S Walker PhD |
| Feasibility of a new concept in MIS UKR for early intervention | In Progress | Peter S Walker PhD |
| Optimal sizing scheme for uncemented THR | In Progress | Peter S Walker PhD |
| Efficacy of lacertus repair for biceps tendon rupture | In Progress | Robert Meislin MD |
| Mechanics of injury of scapho-lunate ligaments – MRI study | In Progress | Steve Lee MD |
| Biomechanics of forces and fixation of the Reverse Shoulder | In Progress | Young Kwon MD |
| Effect of Negative Pressure Wound Therapy on Draining Wounds Following Total Knee Arthroplasty | Upcoming | Francis Pelham MD |