Publications
Sundrud, M.S., Koralov, S., Feuerer, M., Calado, D.P., Kozhaya, A.E., Rhule-Smith, A., Lefebvre, R.E., Unutmaz, D., Mazitschek, R., Waldner, H., Whitman, M., Keller, T., and Rao, A. (2009). Halofuginone inhibits Th17 cell differentiation by activating the amino acid starvation response. Science In press
PMID: 19498172
Unutmaz, D. (2009) RORC2: the master of human Th17 cell programming. Eur. J. Immunol. In press
PMID: 19499530
Vetter, M.L., Johnson, M.E., Antons, A.K., Unutmaz, D., and D'Aquila, R.T. (2009). Differences in APOBEC3G expression in CD4+ T helper lymphocyte subtypes modulate HIV-1 infectivity. PLoS Pathog. Feb;5(2):e1000292.
PMID: 19197360
Antons, A.K., Wang, R., Kalams, S.A., and Unutmaz, D. (2008). Suppression of HIV-specific and allogeneic T cell activation by human regulatory T cells is dependent on the strength of signals. PLoS ONE, 3(8):e2952.
PMID: 18698349
Jiang, Q., Zhang, L., Wang, R., Jeffrey, J., Washburn, M.L., Brouwer, D., Kovalev, G.I., Unutmaz, D., and Su, L. (2008). FoxP3+CD4+ Treg cells play an important role in acute HIV-1 infection in humanized rag2-/-{gamma}C-/- mice in vivo. Blood 112:2858-68
PMID: 18544681
Wang, R., Wan, Q., Kozhaya, L., Fujii, H., Unutmaz, D. (2008). Identification of a regulatory T cell specific cell surface molecule that mediates suppressive signals and induces Foxp3 expression. PLoS ONE 3(7):e2705
PMID: 18628982
PMID: 18454151
Antons, A.K., Wang, R., Oswald-Richter, K., Tseng, M., Arendt, C.W., Kalams, S.A., and Unutmaz, D. (2007). Naïve precursors of human regulatory T cells require FoxP3 for suppression and are susceptible to HIV infection J. Immunol. 180:764-73.
PMID: 18178814
Unutmaz, D., and Vilcek, J.T. (2007). IRF1: a deus ex machina in Th1 differentiation Nat. Immunol. 9:9-10.
PMID: 18087248
Torres, V.J., VanCompernolle, S.E., Sundrud, M.S., Unutmaz, D., and Cover, T.L. (2007). Helicobacter pylori vacuolating cytotoxin inhibits activation-induced proliferation of human T and B lymphocyte subsets. J. Immunol. 179(8):5433-40.
PMID: 17911630
Oswald-Richter, K., Grill, S.M., Leelawong, M., Tseng, M., Kalams, S., Hulgan, T., Haas, D.W., and Unutmaz, D. (2007). Identification of a CCR5 expressing T cell subset that is resistant to R5-tropic HIV infection. PLoS Pathog. Apr;3(4):e58.
PMID: 17465678
PMID: 17183680
Oswald-Richter, K., Torres, V.J., Sundrud, M., VanCompernolle, S.E., Cover, T.L., and Unutmaz, D. (2006). Helicobacter pylori VacA toxin inhibits HIV infection of primary human T cells. J. Virol. 80:11767-75
PMID: 17005643
VanCompernolle, S.E., Taylor J.E., Oswald-Richter, K., Youree B., Jiyang J., Bowie J., Tyler M.J., Conlon J.M., Wade D., Aiken C.A., Dermody T., KewalRamani V.N., Rollins-Smith L., and Unutmaz D. (2005). Amphibian antimicrobial skin peptides potently inhibit HIV infection and transfer of virus from dendritic cells to T cells. J. Virol. 79:11598-606
PMID: 16140737
Sundrud, M., VanCompernolle, S., Eger, K.A., Bruno, T., Subramanian S., Mummidi, S., Ahuja, S.K., and Unutmaz D. (2005). The transcription factor GATA-1 potently represses the expression of the HIV-1 co-receptor CCR5 in human T cells. Blood 106:3440-8
PMID: 16091457
Jelena, S.B., Stanic, A.K., Matsuki, N., Bour-Jordan, H., Bluestone, J.A., Thomas, J.W., Unutmaz, D., Van Kaer L. and Joyce S. (2005). Distinct roles of dendritic cells and B cells in Va14Ja18 natural T (iNKT) cell activation in vivo. J. Immunol. 174-4696-705
PMID: 15814694
Eger, K., and Unutmaz, D. (2005). The innate immune system and HIV pathogenesis. Current HIV/AIDS Reports. 2:10-15
PMID: 16091243
Carlesso, G., Kozlov, E., Prokop, A., Unutmaz, D. and Davidson, J.M. (2005). Nanoparticulate system for efficient gene transfer into refractory cell targets. Biomacromolecules 9;6:1185-1192.
PMID: 15877332
Chen, S., Dang, Q., Unutmaz, D., Pathak, V.K., Maldarelli, F., Powell, D., and Hu, W.S. (2005). Mechanisms of Nonrandom Human Immunodeficiency Virus Type 1 Infection and Double Infection: preference in Virus Entry Is an Important, but not the Sole, Factor. J. Virol. 79:4140-9
PMID: 15767415
Yu Q., Chen D., König R., Mariani R., Unutmaz D. and Landau NR. (2004). APOBEC3B and APOBEC3C Are Potent Inhibitors of Simian Immunodeficiency Virus Replication. J. Biol. Chem. 279:53379-86
PMID: 15466872
Baumann, J.G., Unutmaz, D., Miller, M.D., Breun, S.K.J., Grill, S.M., Mirro, J., Littman, D.R., Rein, A., and KewalRamani V.N., (2004). Murine T cells potently restrict human immunodeficiency virus infection. J. Virol. 78:12537-47
PMID: 15507641
Oswald-Richter, K., Grill, S.M., Shariat, N., Leelawong, M., Sundrud, M.S, Haas, D., and Unutmaz, D. (2004). HIV Infection of Naturally Occurring and Genetically Reprogrammed Human Regulatory T Cells. PLoS Biology 2:E198.
PMID: 15252446
Oswald-Richter, K., Grill, S., Leelwong, M., and Unutmaz, D. (2004). Activation requirements of human T cells for HIV-1 infection. Eur. J. Immunol. 34:1705-14
PMID: 15162441
Eger, K. and Unutmaz, D. (2004). Perturbation of Natural Killer Cell function and receptors during HIV infection. Trends in Microbiology, 12:301-303
PMID: 15223055
Dang Q., Chen, J., Unutmaz, D., Coffin, J.M., Pathak., V.K., Powell, D., KewalRamani, V.N., Maldarelli, F., and Hu, W.S. (2004). Nonramdom HIV-1 infection and double infection via direct and cell-mediated pathways. Proc. Natl. Acad. Sci. USA. 101:632-7
PMID: 14707263
Hulgan, T., Donahue, J.P., Hawkins, C., Unutmaz, D., D'Aquila, R., Raffanti, S., Nicotera, F., Rebeiro, P., Erdem, H., Rueff, M., and Haas, D.W. (2003). Implications of T cell P-glycoprotein activity during HIV-1 infection and its therapy. J. Acquir. Immune Defic. Syndr. 34:119-26
PMID: 14526200
Unutmaz, D. (2003). NKT cells and HIV infection. Microbes and Infection. 5:1041-1047
PMID: 12941396
Sundrud, M., M., Bohks SM., Ni, D., Nagata, K., Alkan, S., Subramaniam A., and Unutmaz D. (2003) Genetic reprogramming of human memory T cells reveals flexible programs of T cell differentiation. J. Immunol. 171:3542-3549
PMID: 14500650
McDonald D., KewalRamani, V.N., Wu L., Bohks, S.M., Unutmaz, D., and Hope T.J. (2003) Recruitment of HIV and its Receptors to Dendritic:T cell Junctions. Science. 300:1295-1297
PMID: 12730499
Motsinger, A., Azimzadeh, A., Stanic, A.K., Van Kaer, L., Joyce, S., and Unutmaz, D. (2003). Identification of CD1d-restricted Macaque Natural Killer T cells. J. Virol. 77: 8153-8.
PMID: 12829854
Jo, D., Lin, Q., Nashabi, A., Mays, D.J., Unutmaz, D., Pietenpol, J.A. and Ruley E. (2003). Cell cycle-dependent transduction of cell-permeant Cre recombinase proteins. J. Cell Biochem. 89:647
PMID: 12858334
Donahue, J.P., Dowdy, D., Ratnam, K.K., Hulgan, T., Price, J., Unutmaz, D., Nicotera, J., Raffanti, S., Becker M., and Haas, D.W. (2003). Effects of Nelfinavir and M8 on lymphocyte P-Glycoprotein activity during antiretroviral therapy. Clin. Pharmacol. Ther. 73:78-86
PMID: 12545146
Unutmaz, D. (2001). T cell signaling mechanisms that regulate HIV-1 infection. Immunol. Res. 23:167-178
PMID: 11444382
