Publications
Braunstein, Steve; Formenti, Silvia C; Schneider, Robert J.
"Acquisition of stable inducible up-regulation of nuclear factor-kappaB by tumor necrosis factor exposure confers increased radiation resistance without increased transformation in breast cancer cells"
Molecular cancer research. 2008 Jan;6(1):78-88.
PMID: 18234964
Fischer I; Cunliffe C; Bollo RJ; Weiner HL; Devinsky O; Ruiz-Tachiquin ME; Venuto T; Pearlman A; Chiriboga L; Schneider RJ; Ostrer H; Miller DC.
"Glioma-like proliferation within tissues excised as tubers in patients with tuberous sclerosis complex"
Acta neuropathologica. 2008 Jul;116(1):67-77.
PMID: 18581125
Lee, C; Gyorgy, A; Maric, D; Sadri, N; Schneider, RJ; Barker, JL; Lawson, M; Agoston, DV. "Members of the NuRD Chromatin Remodeling Complex Interact with AUF1 in Developing Cortical Neurons". Cerebral cortex. 2008; 18: 2909.
PMID: 18413351
Matsumura, Satoko; Wang, Baomei; Kawashima, Noriko; Braunstein, Steve; Badura, Michelle; Cameron, Thomas O; Babb, James S; Schneider, Robert J; Formenti, Silvia C; Dustin, Michael L; Demaria, Sandra. "Radiation-induced CXCL16 release by breast cancer cells attracts effector T cells". Journal of immunology. 2008; 181: 3099.
PMID: 18713980
Ramirez-Valle, Francisco; Braunstein, Steve; Zavadil, Jiri; Formenti, Silvia C; Schneider, Robert J. "eIF4GI links nutrient sensing by mTOR to cell proliferation and inhibition of autophagy". Journal of cell biology. 2008; 181: 293.
PMID: 18426977
Bergman, N; Moraes, KCM; Anderson, JR; Zaric, B; Kambach, C; Schneider, RJ; Wilusz, CJ; Wilusz, J. "Lsm proteins bind and stabilize RNAs containing 5 ' poly(A) tracts". Nature structural & molecular biology. 2007; 14: 824.
PMID: 17694069
Braunstein, Steve; Karpisheva, Ksenia; Pola, Carolina; Goldberg, Judith; Hochman, Tsivia; Yee, Herman; Cangiarella, Joan; Arju, Rezina; Formenti, Silvia C; Schneider, Robert J. "A hypoxia-controlled cap-dependent to cap-independent translation switch in breast cancer". Molecular cell. 2007; 28: 501.
PMID: 17996713
Demaria, S; Wang, B; Badura, M; Matsumura, S; Kawashima, N; Cameron, T; Dustin, M; Schneider, RJ; Formenti, SC. "Exploiting breast cancer cells stress response to ionizing radiation to improve the effectiveness of immunotherapy [Abstract]". International journal of radiation oncology biology physics. 2007; 69: S597.
Lerman, O; Grieves, M; Levine, J; Schneider, R; Formenti, S. "Single-dose radiation stimulates induction of stromal derived factor-1 expression and endothelial cell migration independently of hypoxia activation [Abstract]". International journal of radiation oncology biology physics. 2007; 69: S592.
Pola, C; Formenti, SC; Schneider, RJ. "Vitronectin in the tumor microenvironment promotes breast cancer cell proliferation and elevated protein synthesis despite hypoxia by integrin alpha v beta 3 activation of the mTOR/4E-BP1 pathway [Abstract]". Breast cancer research & treatment. 2007; 106: S162.
Puro R; Schneider RJ. "TNF Activates a Conserved Innate Antiviral Response to HBV that Destabilizes Nucleocapsids and Reduces Nuclear Viral DNA". Journal of virology. 2007; 81: 7351.
PMID: 17475655
Schneider, RJ; Braunstein, S; Badura, M; Formenti, SC. "Elevated levels of translation initiation factor eIF4G suppresses Radiation(IR)-induced autophagy and cell death [Abstract]". International journal of radiation oncology biology physics. 2007; 69: S593.
Silvera, D; Arju, R; Darvishian, F; Levine, PH; Formenli, SC; Schneider, RJ. "Inflammatory breast cancer pathogenesis is mediated in significant part by translation initiation factor eIF4G amplification and unorthodox protein synthesis [Abstract]". Breast cancer research & treatment. 2007; 106: S18 (#J0133410)
Zavadil, Jiri; Narasimhan, Manisha; Blumenberg, Miroslav; Schneider, Robert J. "Transforming growth factor-beta and microRNA:mRNA regulatory networks in epithelial plasticity". Cells tissues organs. 2007; 185: 157.
PMID: 17587821
Bouchard, Michael J; Wang, Lihua; Schneider, Robert J. "Activation of focal adhesion kinase by hepatitis B virus HBx protein: multiple functions in viral replication". Journal of virology. 2006; 80: 4406.
PMID: 16611900
Braunstein, S; Badura, M; Xi, Q; Formenti, SC; Schneider, RJ. "Ionizing radiation regulates protein synthesis through two novel ATM-independent and ATM-dependent pathways involving mTOR and translation regulator, 4E-BP1 [Abstract]". International journal of radiation oncology biology physics. 2006; 66: S71.)
Connolly E; Braunstein S; Formenti S; Schneider RJ. "Hypoxia inhibits protein synthesis through a 4E-BP1 and elongation factor 2 kinase pathway controlled by mTOR and uncoupled in breast cancer cells". Molecular & cellular biology. 2006; 26: 3955.
PMID: 16648488
Connolly, E P; Thuillier, V; Rouy, D; Bouetard, G; Schneider, R J. "Inhibition of Cap-initiation complexes linked to a novel mechanism of eIF4G depletion in acute myocardial ischemia". Cell death & differentiation. 2006; 13: 1586.
PMID: 16439989
He, Cheng; Schneider, Robert. "14-3-3sigma is a p37 AUF1-binding protein that facilitates AUF1 transport and AU-rich mRNA decay". EMBO journal. 2006; 25: 3823.
Karpisheva, KV; Xi, QR; Braunstein, S; Melamed, J; Goldberg, J; Schneider, R. "MTOR/4E-BP1 pathway is a translational regulator of prostate cancer progression [Abstract]". FASEB journal. 2006; 20: A109.
Karpisheva, K; Braunstein, S; Goldberg, J; Singh, B; Pola, C; Formenti, SC; Schneider, RJ. "A translationally controlled angiogenic switch in locally advanced breast cancer [Abstract]". Breast cancer research & treatment. 2006; 100: S11.
Lu JY; Bergman N; Sadri N; Schneider RJ. "Assembly of AUF1 with eIF4G-poly(A) binding protein complex suggests a translation function in AU-rich mRNA decay". RNA. 2006; 12: 883.
PMID: 16556936
Lu, Jin-Yu; Sadri, Navid; Schneider, Robert J. "Endotoxic shock in AUF1 knockout mice mediated by failure to degrade proinflammatory cytokine mRNAs". Genes & development. 2006; 20: 3174.
PMID: 17085481
Oxelmark, Ellinor; Roth, Jennifer M; Brooks, Peter C; Braunstein, Steven E; Schneider, Robert J; Garabedian, Michael J. "The cochaperone p23 differentially regulates estrogen receptor target genes and promotes tumor cell adhesion and invasion". Molecular & cellular biology. 2006; 26: 5205.
PMID: 16809759
Silvera, D; Formenti, SC; Schneider, RJ. "Over-expression of initiation factor eIF4G typifies inflammatory breast cancer and is crucial for tumor growth, VEGF expression and angiogenesis [Abstract]". Breast cancer research & treatment. 2006; 100: S168.
Wang, B; Badura, M; He, C; Cameron, T; Dustin, M; Formenti, SC; Schneider, RJ; Demaria, S. "CXCR6 and CXCL16 are expressed by breast cancer cells and may play a dual role in tumor progression [Abstract]". Breast cancer research & treatment. 2006; 100: S299.
Zlotnick, Caron; Johnson, Dawn M; Stout, Robert L; Zywiak, William H; Johnson, Jennifer E; Schneider, Robert J. "Childhood abuse and intake severity in alcohol disorder patients". Journal of traumatic stress. 2006; 19: 949.
PMID: 17195983
Ellerin, Bruce E; Schneider, Robert J; Stern, Arnold; Toniolo, Paolo G; Formenti, Silvia C. "Ethical, legal, and social issues related to genomics and cancer research: the impending crisis". Journal of the American College of Radiology : JACR. 2005; 2: 919.
PMID: 17411966
Engelsman, Martijn; Rosenthal, Stanley J; Michaud, Susan L; Adams, Judith A; Schneider, Robert J; Bradley, Stephen G; Flanz, Jacob B; Kooy, Hanne M. "Intra- and interfractional patient motion for a variety of immobilization devices". Medical physics. 2005; 32: 3468.
PMID: 16372417
Cuesta, R., Xi, Q. and Schneider, R.J. (2004). “Structural basis for competitive inhibition of eIF4G-Mnk1 interaction by adenovirus 100k protein.” J. Virol. 2004 Jul;78(14):7707-16.
PMID: 15220445
Lu, J.-Y. and Schneider, R.J. (2004) “Tissue distribution of AU-rich mRNA binding proteins involved in regulation of mRNA decay.” J. Biol. Chem. 279: 12974-12979.
PMID: 14711832
Sarkar, B., Xi, Quoran, Liu, J.-Y., Schneider, R.J. (2003) “Selective degradation of AU-rich mRNAs promoted by the p37 AUF1 protein isoforms.” Mol. Cell. Biol. 23(18):6685-93.
PMID: 12944492
Bouchard, M.J., Puro, R.J., Wang, L.H. and Schneider R.J. (2003). “Activation and inhibition of cellular calcium and tyrosine kinase signaling pathways identify targets of the HBx protein involved in HBV replication.” J. Virol.77(14):7713-9.
PMID: 12829810
Biermer, M., Puro, R., and Schneider, R.J. (2003). “TNF-a inhibition of hepatitis B virus replication involves disruption of capsid integrity through activation of NF-kB.” J. Virol. 77: 4033-4042.
PMID: 12634363
Yaman, I., Fernandez, J., Sarkar, B., Schneider, R. J., Snider, M. D., Nagy, L. E., and Hatzoglou, M. (2002). “Nutritional control of mRNA stability is mediated by a conserved AU-rich element that binds the cytoplasmic shuttling protein HuR.” J. Biol. Chem. 277: 41539-41546.
PMID: 12196519
Jamal, S., and R.J. Schneider, (2002) "UV-induction of keratinocyte endothelin-1 downregulates E-cadherin in melanocytes and melanoma cells." J. Clinical Invest. 110:443-452.
PMID: 12189238
Laroia, G., and R.J. Schneider, (2002) "Alternate exon insertion controls
selective ubiquitination and degradation of different AUF1 protein
isoforms." Nucl. Acids Res. 30:1-7.
PMID: 12136087
Laroia, G., B. Sarkar, and R.J. Schneider, (2002) "Ubiquitin-dependent mechanism regulates rapid tuurnover of AU-rich cytokine mRNAs." Proc. Natl. Acad.Sci. USA, 99:1842-1846.
PMID: 11842200
Cuesta, R., K. Xi, and R.J. Schneider, (2002) "Preferential Translation Of Adenovirus mRNAs In Infected Cells." Cold Spring Harbor Symposia Quantitative Biology, LXVI:259-267.
PMID: 12762027
Bouchard, M., L.-H. Wang and R.J. Schneider, (2001) "Ca2+ Signaling by HBx Protein in Hepatitis B Virus Replication." Science, 294:2376-2378.
PMID: 11743208
Su, F., and R.J. Schneider. (2001) "Role of NF-kB and Myc proteins in apoptosis induced by HBV HBx protein." Journal of Virology 75:215-225.
PMID: 11119591
Bouchard, M., S. Giannakopoulos, E. Wang, N. Tanese, and R.J. Schneider. (2001) "HBV HBx protein activation of cyclin A-cdk2 complexes and G1 cell transit via a Src kinase pathway." Journal of Virology, 75:4247-4257.
PMID: 11287574
Schneider, R.J., and D. Ganem. (2001) "Hepatitis B virus." In Field's Virology, Lippincott, New York.
Cuesta, R., K. Xi, and R.J. Schneider. (2000) "Adenovirus-specific translation by displacement of kinase Mnk1 from cap-initiation complex eIF4F." EMBO Journal, 19:3465-3474.
PMID: 10880459
Schneider, R.J. (2000) "Heat Shock Translational Control." In Translational Control (eds. M. Mathews, J.W.B. Hershey and N. Sonenberg). Cold Spring Harbor Press, New York. pp. 581-594.
Schneider, R.J. (2000) "Adenovirus Translational Control." In Translational Control (eds. M. Mathews, J.W.B. Hershey and N. Sonenberg). Cold Spring Harbor Press, New York. pp. 901-914.
Cuesta, R., G. Laroia, and R.J. Schneider. (2000) "Chaperone Hsp27 inhibits translation during heat shock by binding eIF4G and facilitating dissociation of cap-initiation complexes." Genes and Development, 14:1460-1470.
PMID: 10859165
Yueh, A., and R.J. Schneider. (2000) "Translation by ribosome shunting on adenovirus and hsp70 mRNAs facilitated by complementarity to 18S rRNA." Genes and Development, 14:414-421.
PMID: 10691734
Klein N; Curatola AM; Schneider RJ. "Calcium-induced stabilization of AU-rich short-lived mRNAs is a common default response". Gene expression. 1999; 7: 357.
PMID: 10440236
Klein, N., M. Bouchard, L.-H. Wang, C. Kobarg, and R.J. Schneider. (1999) "Src kinases involved in HBV replication." EMBO Journal, 18:5019-5027.
PMID: 10487754
Laroia, G., R. Cuesta, G. Brewer, and R.J. Schneider. (1999) "Control of mRNA decay by heat shock-ubiquitin-proteasome pathway." Science, 284:499-502.
PMID: 10205060
Klein, N., and R.J. Schneider. (1997) "Activation of Src family kinases by HBV HBx protein, and coupled signaling to Ras." Molecular & Cellular Biology, 17:6427-6436.
PMID: 9343405
Su, F., and R.J. Schneider. (1997) "Hepatitis B virus HBx protein sensitizes cells to apoptotic killing by TNFa." Proc. Natl. Acad. Sci. USA, 94:8744-8749.
PMID: 9238048
Feigenblum, D., and R.J. Schneider. (1996) "Cap-binding protein (eukaryotic initiation factor 4E) and 4E-inactivating protein BP-1 independently regulate cap-dependent translation." Molecular & Cellular Biology, 16:5450-5457.
PMID: 8816458
Benn, J., F. Su, M. Doria, and R.J. Schneider. (1996) "Hepatitis B virus HBx protein induces transcription factor AP-1 by activation of extracellular signal-regulated and c-Jun N-terminal mitogen-activated protein kinases." Journal of Virology, 70:4978-4985.
PMID: 8764004
Su, F., and R.J. Schneider. (1996) "Hepatitis B virus HBx protein activates transcription factor NF-kappaB by acting on multiple cytoplasmic inhibitors of rel-related proteins." Journal of Virology, 70:4558-4566.
PMID: 8676482
Yueh, A., and R.J. Schneider. (1996) "Selective translation initiation by ribosome jumping in adenovirus-infected and heat-shocked cells." Genes & Development, 10:1557-1567.
PMID: 8666238