Mohr Lab
Research Interests
Figure 3. eIF4E (open crescent) bound to the 5’mRNA cap (7m) associates with the translational repressor 4E-BP1. Upon phosphorylation by the cellular kinase mTOR, 4E-BP1 is released from eIF4E allowing the recruitment of eIF4G and eIF4F complex assembly.
Research Interests
Figure 3. eIF4E (open crescent) bound to the 5’mRNA cap (7m) associates with the translational repressor 4E-BP1. Upon phosphorylation by the cellular kinase mTOR, 4E-BP1 is released from eIF4E allowing the recruitment of eIF4G and eIF4F complex assembly.