Publications
Pearce, M.J., J. Minsteris, J. Ferreyra, S.P. Gygi, and K.H. Darwin. Ubiquitin-like protein involved in the proteasome pathway of Mycobacterium tuberculosis. Science. 2 October 2008 (DOI:10.1126/science.1163885).
Festa, R.A., M.J. Pearce, and K.H. Darwin. 2007. Characterization of the proteasome accessory factor (paf) operon in Mycobacterium tuberculosis. J. Bacteriol. 189:3044-3050.
Pearce, M.J., P. Arora, R.A. Festa, S.M. Butler-Wu, R.S. Gokhale, and K.H. Darwin. 2006. Identification of substrates of the Mycobacterium tuberculosis proteasome. EMBO J. 25:5423-5432.
Butler, S.M., R.A. Festa, M.J. Pearce, and K.H. Darwin. 2006. Self-compartmentalized Bacterial Proteases and Pathogenesis. Mol. Microbiol. 60:553-562.
Darwin KH, Nathan CF.(2005)"Role for nucleotide excision repair in virulence of Mycobacterium tuberculosis". Infect Immun. 2005 Aug;73(8):4581-7.
Hisert KB, MacCoss M, Shiloh MU, Darwin KH, Singh S, Jones RA, Ehrt S, Zhang Z, Gaffney BL, Gandotra S, Holden DW, Murray D, Nathan C.(2005) "A glutamate-alanine-leucine (EAL) domain protein of Salmonella controls bacterial survival in mice, antioxidant defence and killing of macrophages: role of cyclic diGMP". Mol Microbiol. Jun; 56(5):1234-45.
Darwin KH, Lin G, Chen Z, Li H, Nathan CF (2005) "Characterization of a Mycobacterium tuberculosis proteasomal ATPase homologue" Mol Microbiol. 2005 Jan; 55(2):561-71.
Darwin, K. H., S. Ehrt, J.-C. Gutierrez-Ramos, N. Weich, and C. F. Nathan. 2003. The proteasome of Mycobacterium tuberculosis is required for resistance to nitric oxide. Science. 302: 1963-1966.
Darwin, K. H. and V. L. Miller. 2001. Type III secretion chaperone-dependent regulation: activation of virulence genes by SicA and InvF in Salmonella typhimurium . EMBO J . 20: 1850-1862.
Darwin, K. H., L. S. Robinson, and V. L. Miller. 2001. SigE is a chaperone for the Salmonella enterica Serovar typhimurium invasion protein SigD. J. Bacteriol. 183: 1452-1454.
Darwin, K. H. and V. L. Miller. 2000. The putative invasion protein chaperone SicA acts together with InvF to activate the expression of Salmonella typhimurium virulence genes. Mol. Microbiol. 35: 949-959.
Darwin, K. H. and V. L. Miller. 1999. InvF is required for the expression of genes encoding proteins secreted by the SPI1 type III secretion apparatus in Salmonella typhimurium . J. Bacteriol . 181:4949-4954.
Darwin, K. H. and V. L. Miller. 1999. Molecular basis of the interaction of Salmonella with the intestinal mucosa. Clin. Microbiol. Rev . 12:405-428.
Hong*, K. H. and V. L. Miller. 1998. Identification of a novel Salmonella invasion locus homologous to Shigella sp. ipgDE . J. Bacteriol . 180:1793-1802.
McEwen, J. E., K. H. Hong*, S. Park, and G. T. Preciado. 1993. Sequence and chromosomal localization of two PET genes required for cytochrome c oxidase assembly in Saccharomyces cerevisiae . Curr. Genet . 23:9-14.
*indicates maiden name