Publications
KSHV transformation and pathogenesis
Friedman-Kien, A.E., B.R. Saltzman, Y. Cao, M. Nestor, M. Mirabile, J.J. Li. (1990) "Kaposi's sarcoma in HIV-negative homosexual men." The Lancet, 335:168-69.
Cao Y, A.E. Friedman-Kien, M. Mirabile, X.L. Li, M. Alam, D. Dieterich, D.D. Ho. (1990) "HIV-1 neutralizing antibodies in urine from seropositive individuals." J Acq Imm Def Synd, 3(3):193-99.
Friedman-Kien, A.E., R. Ostreicher, B.R. Saltzman. (1990) "Clinical manifestations of classical, endemic African, and epidemic AIDS-associated Kaposi's sarcoma." J Am Acad Dermatol (supplement), 6:1250-53.
Li, J.J., A.E. Friedman-Kien, Y.Q. Huang, M. Mirabile, Y. Cao. (1990) "HIV-1 DNA proviral sequences in fresh urine pellets from HIV-1 seropositive persons." The Lancet, 335:1590-91.
Krigel, R.L., A.E. Friedman-Kien. (1990) "Epidemic Kaposi's sarcoma." Seminars in Oncology, 17(3):350-60.
Friedman-Kien, A.E., A. Buchbinder. (1991) "Clinical aspects of epidemic Kaposi's sarcoma." Cancer Surveys: Cancer, HIV and AIDS, 10:39-52.
Orlow, S.J., A.E. Friedman-Kien. (1991) "Cutaneous manifestations of AIDS." Dermatology Today and Tomorrow, July:4-7.
Peterman, T.A., H.W. Jaffe, A.E. Friedman-Kien, R.A. Weiss. (1991) "The etiology of Kaposi's sarcoma." Cancer Surveys, 10:23-37.
Buchbinder A, A.E. Friedman-Kien. (1991) "Clinical aspects of epidemic Kaposi's sarcoma." Cancer Surveys, 10:39-52.
Friedman-Kien, A.E., Y.Q. Huang, J.J. Li, M.G. Rush, B.J. Poiesz, A. Nicolaides, M. Jacobson, W.G. Zhang, E. Coutavas, M.A. Abbott. (1992) "HPV-16-related DNA sequences in Kaposi's sarcoma." Lancet, 339:515-518.
Nickoloff, B.J., Y.Q. Huang, J.J. Li, A.E. Friedman-Kien. (1992) "Immunohistochemical detection of papilloma virus antigens in Kaposi's sarcoma." Lancet, 339:548-549.
Li, J.J., Y.Q. Huang, B.J. Poiesz, A.E. Friedman-Kien. (1992) "Detection of human immunodeficiency virus type 1 (HIV-1) in urine cell pellets from HIV-1 seropositive individuals." J Clin Microbio, 30(5):1051-1055.
Huang, Y.Q., J.J. Li, A. Nicolaides, W.G. Zhang, A.E. Friedman-Kien. (1992) "Detection of FGF6 expression in Kaposi's sarcoma lesions." Lancet, 339.
Huang, Y.Q., A. Buchbinder, J.J. Li, A. Nicolaides, W.G. Zhang, A.E. Friedman-Kien. (1992) "The absence of Tat sequences in tissues of HIV-1 negative patients with epidemic Kaposi's sarcoma." AIDS, 6:1139-42.
Huang, Y.Q., J.J. Li, D. Moscatelli, C. Basilico, A. Nicolaides, W.G. Zhang, B.J. Poiesz, A.E. Friedman-Kien. (1993) "Expression of int-2 oncogene in Kaposi's sarcoma lesions." J Clin Invest, 91:1191-1197.
Huang, Y.Q., J.J. Li, S.W. Kim, A. Nicolaides, W.G. Zhang, J. Le, B.J. Poiesz, A.E. Friedman-Kien. (1993) "HIV-1 infection and modulation of cytokine and growth factor expression in Kaposi's sarcoma-derived cells in vitro." AIDS, 7:317-22.
Huang, Y.Q., J.J. Li, A. Nicolaides, W.G. Zhang, A.E. Friedman-Kien. (1993) "Increased expression of fibroblast growth factors and their receptors by protamine and suramin on Kaposi's sarcoma-derived cells." Anticancer Res, 13:887-890.
Huang, Y.Q., A.E. Friedman-Kien, J.J. Li, B.J. Nickoloff. (1993) "Cultured Kaposi's sarcoma cell lines express factor XIIIa, CD14, and VCAM-1, but not factor VIII or ELAM-1." Arch Derm, 129:1291-1296.
Li, J.J., Y.Q. Huang, D. Moscatelli, A. Nicolaides, W.G. Zhang, A.E. Friedman-Kien. (1993) "Expression of fibroblast growth factors and their receptors in acquired immunodeficiency syndrome-associated Kaposi's sarcoma tissue and derived cells." Cancer, 72:2253-59.
Kostolansky, F., J.J. Li, A.E. Friedman-Kien. (1993) "Patterns of multiple-drug hypersensitivities in HIV-infected patients." AIDS, 7(11):1531-32.
Balfour Jr., H.H., C. Benson, J. Braun, B. Cassens, A. Erice, A.E. Friedman-Kien, T. Klein, B. Polsky, S. Safrin. (1994) "Management of acyclovir-resistant herpes simplex and varicella-zoster virus infections." J Acquired Immune Deficiency Syndromes, 7:254-260.
Nicolaides, A., Y.Q. Huang, J.J. Li, W.G. Zhang, A.E. Friedman-Kien. (1994) "Gene amplification and multiple mutations of the K-ras oncogene in Kaposi's sarcoma." Anticancer Res, 14:921-926.
Huang, Y.Q., B. Raphael, A. Buchbinder, J.J. Li, W.G. Zhang, A.E. Friedman-Kien. (1994) "Rearrangement and expression of MDM2 oncogene in chronic lymphocytic leukemia." Amer J of Hematol, 47:139-41.
Wernz, J.C., B. Taubes, A. Frazein, C. Wasserheit, A. Friedberg, A.E. Friedman-Kien. (1994) "Epidemic Kaposi's sarcoma (EKS) response to Dox-SL after initial response and then progression on Daunoxome." In: Proceedings of the second international congress on drug therapy in HIV infection Glasgow, Scotland.
Huang, Y.Q., J.J. Li, M. Kaplan, B.J. Poiesz, W.C. Zhang, D. Feiner, E. Katabira, A.E. Friedman-Kien. (1995) "Human herpesvirus-like nucleic acid in various forms of Kaposi's sarcoma." Lancet, 345:759-761.
A.E. Friedman-Kien. (1995) "Management of condylomata acuminata with Alferon N injection, interferon alfa-n3 (human leukocyte derived)." Am J Obstet Gynecol, 172(2, part 2):1359-1368.
Drotman, D.P., T.A. Peterman, A.E. Friedman-Kien. (1995) "Kaposi's sarcoma: how can epidemiology help find the cause?" In: Dudlick B., ed. Dermatologic Clinics. Philadelphia, W.B. Saunders, 13(3):575-581.
Li, J.J., Y.Q. Huang, C.J. Cockerell, W.G. Zhang, A. Nicolaides, A.E. Friedman-Kien. (1997) "Expression and mutation of the tumor suppressor gene p53 in AIDS-associated Kaposi's sarcoma." Am J Dermapathol, 19(4):373-378.
Huang, Y.Q., J.J. Li, D. Moscatelli, W.G. Zhang, A. Nicolaides, A.E. Friedman-Kien. () "NIH3T3 cells transformed by FGF3 induced mouse tumors resemble Kaposi's sarcoma." J Clin Invest 1993; 91:1191-7.
Huang, Y.Q., J.J. Li, B.J. Poiesz, M.H. Kaplan, A.E. Friedman-Kien. (1997) "Detection of Herpesvirus-like DNA sequences in matched speicmes of semen and blood from patients with AIDS-related Kaposi's sarcoma by polymerase chain reaction in situ hybridization." Am J Pathol, 150:147-153.
Li, J.J., Y.Q. Huang, C.J. Cockerell, A.E. Friedman-Kien. (1996) "Localization of human herpes-like virus type 8 in vascular endothelial cells and perivascular spindle-shaped cells of Kaposi's sarcoma lesions by in situ hybridization." Amer J Pathol, 148:1741-1748.
Huang, Y.Q., J.J. Li, W.G. Zhang, D. Feiner, A.E. Friedman-Kien. (1996) "Transcription of human herpesvirus-like agent (HHV-8) in Kaposi's sarcoma." J Clin Invest, 97(12):2803-2806.
Chatlynne, L.G., W. Lapps, M. Handy, Y.Q. Huang, R. Masood, A.S. Hamilton, J.W. Said, H.P. Koeffler, M.H. Kaplan, A.E. Friedman-Kien. (1998) "Gill PS, Whitman JE, Ablashi DV. Detection of titration of human herpesvirus-8-specific antibodies in sera from blood donors, acquired immunodeficiency syndrome patients, and Kaposi's sarcoma patients using a whole virus enzyme-linked immunosorbent assay." Blood, 92(1):53-58.
Cockerell, C.J., and A.E. Friedman-Kien. (1999) "Cutaneous Manifestations of HIV Infection. Chapter in: Textbook of AIDS Medicine, 2nd Ed., Thomas C. Merigan, Jr., MD, John G. Bartlett, MD, Dani Bolognesi, PhD, Eds., William & Wilkins, Publisher. pp.499-520.
Neipel, F., J.C. Albrecht, A. Ensser, Y.Q. Huang, J.J. Li, A.E. Friedman-Kien, B. Fleckenstein. (1997) "Human herpesvirus 8 encodes a homolog of interleukin-6." J Virology, 71(1):839-842.
Cerimele, F., F. Currelli, S. Ely, A.E. Friedman-Kien, E.Cesarman, and O. Flore. (2001) "Kaposi's sarcoma-associated herpesvirus can productively infect primary human keratinocytes and alter their growth properties." J Virology, 2435-2443.