Selected Recent Publications
Peters W, Scott HM, Chambers HF, Flynn JL, Charo IF, and Ernst JD (2001) Chemokine receptor 2 serves an early and essential role in cellular immunity to Mycobacterium tuberculosis. Proc Natl Acad Sci 98: 7958-7963
Sonda S, Ting L-M, Novak S, Kim K, Maher JJ, Farese R.V. Jr. and Ernst JD (2001) Cholesterol esterification by host and parasite is essential for optimal replication of Toxoplasma gondii. J Biol Chem 276: 34434-34440
Kincaid EZ and Ernst JD: Mycobacterium tuberculosis exerts gene-selective inhibition of transcriptional responses to IFNgamma without inhibiting STAT1 function. (2003) J Immunol 171:2042-2049
Nagabhushanam V, Ting L-M, Escaron CJ, Solache A, Zhang Y, and Ernst JD (2003) Innate inhibition of adaptive immunity: M. tuberculosis-induced IL-6 inhibits macrophage responses to IFNgamma J Immunol 171: 4750-4757
Fortune SM, Solache A, Jaeger A, Hill PJ, Belisle JT, Bloom BR, Rubin EJ, and Ernst JD (2004) M. tuberculosis inhibits macrophage responses to IFN-g through MyD88-dependent and MyD88-independent mechanisms. J Immunol, 172: 6272-6280
Peters W, Cyster J, Mack, M, Schlondorff D, Wolf A, Ernst JD, and Charo IF (2004) Chemokine receptor 2-dependent trafficking of F4/80dim macrophages and CD11cdim/intermediate dendritic cells is crucial for T cell recruitment to lungs infected with Mycobacterium tuberculosis. J Immunol 172: 7647-7653
Banaiee N, Kincaid EZ, Buchwald U, Jacobs WR Jr, and Ernst, JD (2006) Potent inhibition of responses to IFNgamma by Mycobacterium tuberculosis requires Toll-like Receptor 2 but not mature bacterial lipoproteins. In Press.